Best TWAS P=9.17e-09 · Best GWAS P=1.95e-09 conditioned to 8.24e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | EFCAB5 | 0.11 | 0.18 | blup | 392 | 0.17 | 1.7e-20 | -4.7 | -5.4 | 8.7e-08 | -0.23 | 0.38 | 0.62 | FALSE |
| 2 | GTEx | Brain Cortex | GOSR1 | 0.20 | 0.20 | enet | 7 | 0.18 | 1.4e-05 | 4.6 | 5.2 | 1.6e-07 | 0.16 | 0.33 | 0.60 | FALSE |
| 3 | GTEx | Thyroid | ANKRD13B | 0.23 | 0.12 | lasso | 6 | 0.18 | 2.3e-13 | -3.3 | -5.5 | 4.5e-08 | -0.73 | 0.04 | 0.96 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | CCDC55 | 0.15 | 0.01 | blup | 64 | 0.04 | 1.9e-03 | -5.2 | 5.7 | 9.2e-09 | 0.31 | 0.02 | 0.55 | TRUE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | EFCAB5 | 0.04 | 0.03 | enet | 10 | 0.02 | 6.0e-03 | -4.7 | -5.1 | 2.7e-07 | -0.20 | 0.04 | 0.92 | FALSE |