Best TWAS P=1.06e-08 · Best GWAS P=2.1e-09 conditioned to 0.0197
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Thyroid | DHRS7B | 0.17 | 0.02 | enet | 22 | 0.11 | 1.2e-08 | -4.7 | -5.2 | 2.6e-07 | 0.26 | 0.60 | 0.30 | FALSE |
| 2 | GTEx | Thyroid | KCNJ12 | 0.36 | 0.23 | lasso | 5 | 0.25 | 2.9e-19 | -4.5 | -5.7 | 1.1e-08 | 0.81 | 0.57 | 0.42 | TRUE |