[Hub]/) : Traits : Leg fat mass (left) :

chr17:41,555,474-42,998,534

Best TWAS P=5.16e-10 · Best GWAS P=6.09e-10 conditioned to 0.147

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum ASB16-AS1 0.14 0.12 lasso 5 0.10 9.8e-06 5.4 -5.5 4.5e-08 -0.88 0.12 0.87 FALSE
2 GTEx Breast Mammary Tissue (Female) ASB16-AS1 0.08 0.04 lasso 2 0.06 7.9e-03 5.4 -5.4 5.7e-08 -0.87 0.06 0.51 FALSE
3 GTEx Cells Transformed fibroblasts ASB16 0.14 0.14 lasso 3 0.12 2.0e-09 5.5 -5.5 3.0e-08 -0.82 0.09 0.91 FALSE
4 GTEx Cells Transformed fibroblasts ASB16-AS1 0.17 0.17 lasso 4 0.16 2.3e-12 5.5 -5.3 1.0e-07 -0.77 0.09 0.91 FALSE
5 GTEx Esophagus Mucosa ASB16 0.10 0.10 lasso 4 0.08 8.2e-06 5.5 -5.5 3.3e-08 -0.82 0.10 0.89 FALSE
6 GTEx Heart Left Ventricle RP5-882C2.2 0.14 0.08 lasso 5 0.10 8.1e-06 5.2 -5.4 6.5e-08 -0.78 0.08 0.90 FALSE
7 GTEx Nerve Tibial ASB16 0.12 0.07 lasso 5 0.07 7.5e-06 5.5 -5.5 4.5e-08 -0.85 0.09 0.91 FALSE
8 GTEx Nerve Tibial ASB16-AS1 0.17 0.15 lasso 5 0.16 1.4e-11 5.5 -5.2 2.2e-07 -0.79 0.10 0.90 FALSE
9 GTEx Skin Sun Exposed Lower leg ASB16-AS1 0.13 0.09 lasso 5 0.07 2.7e-06 5.2 -5.2 2.3e-07 -0.80 0.13 0.87 FALSE
10 GTEx Testis ASB16-AS1 0.35 0.25 lasso 5 0.23 1.0e-10 5.5 -5.6 2.1e-08 -0.82 0.08 0.92 FALSE
11 GTEx Thyroid RP5-882C2.2 0.10 0.07 lasso 3 0.07 2.9e-06 5.5 -5.4 5.4e-08 -0.80 0.04 0.94 FALSE
12 GTEx Thyroid ASB16-AS1 0.14 0.06 lasso 2 0.04 5.4e-04 5.5 -5.6 2.8e-08 -0.82 0.09 0.84 FALSE
13 GTEx Whole Blood ASB16-AS1 0.14 0.05 lasso 6 0.04 3.1e-04 5.5 -5.6 2.2e-08 -0.83 0.11 0.89 FALSE
14 The Cancer Genome Atlas Bladder Urothelial Carcinoma C17orf65 0.03 0.00 blup 37 0.01 2.3e-02 5.5 -6.2 5.2e-10 -0.89 0.03 0.78 TRUE
15 The Cancer Genome Atlas Colon Adenocarcinoma ASB16 0.05 0.06 blup 40 0.05 4.6e-04 5.3 -5.6 2.8e-08 -0.85 0.07 0.81 FALSE
16 The Cancer Genome Atlas Colon Adenocarcinoma C17orf65 0.05 0.06 blup 38 0.05 4.2e-04 4.2 -5.7 1.4e-08 -0.86 0.08 0.80 FALSE
17 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ASB16 0.02 0.02 blup 39 0.02 3.8e-03 5.9 -6.1 8.7e-10 -0.86 0.02 0.46 FALSE
18 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C17orf65 0.03 0.01 lasso 10 0.02 3.6e-03 5.8 -5.9 3.6e-09 -0.81 0.03 0.87 FALSE
19 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ASB16 0.02 0.03 blup 40 0.03 1.3e-04 5.2 -5.8 5.4e-09 -0.89 0.10 0.88 FALSE
20 The Cancer Genome Atlas Brain Lower Grade Glioma ASB16 0.03 0.03 lasso 3 0.03 3.2e-04 5.4 -5.4 7.4e-08 -0.88 0.08 0.85 FALSE
21 The Cancer Genome Atlas Brain Lower Grade Glioma C17orf65 0.04 0.04 blup 37 0.03 1.4e-04 5.5 -5.4 8.7e-08 -0.83 0.10 0.88 FALSE
22 The Cancer Genome Atlas Lung Squamous Cell Carcinoma ASB16 0.04 0.04 lasso 4 0.03 1.8e-04 5.9 -5.9 4.0e-09 -0.87 0.03 0.95 FALSE
23 The Cancer Genome Atlas Lung Squamous Cell Carcinoma C17orf65 0.07 0.05 lasso 6 0.05 3.1e-06 5.5 -5.2 2.1e-07 -0.73 0.06 0.94 FALSE
24 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma C17orf65 0.04 0.03 blup 39 0.03 2.7e-03 5.9 -5.4 7.8e-08 -0.87 0.02 0.81 FALSE
25 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma C17orf65 0.09 0.09 enet 8 0.08 2.9e-04 5.3 -5.7 1.2e-08 -0.88 0.04 0.90 FALSE
26 The Cancer Genome Atlas Testicular Germ Cell Tumors C17orf65 0.07 0.02 blup 38 0.04 1.1e-02 5.4 -6.0 1.4e-09 -0.89 0.02 0.32 FALSE
27 The Cancer Genome Atlas Thyroid Carcinoma C17orf65 0.03 0.03 lasso 7 0.03 3.8e-04 5.5 -5.8 7.8e-09 -0.86 0.04 0.88 FALSE