Best TWAS P=1.08e-10 · Best GWAS P=5.04e-10 conditioned to 0.0587
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | BCL2L13 | 0.19 | 0.09 | lasso | 13 | 0.12 | 5.9e-15 | 6.2 | -6.0 | 2.7e-09 | -0.87 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Artery Tibial | BID | 0.15 | 0.07 | enet | 21 | 0.07 | 6.3e-06 | 5.4 | -5.6 | 2.2e-08 | -0.83 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Brain Caudate basal ganglia | BID | 0.28 | 0.16 | lasso | 10 | 0.15 | 5.6e-05 | 5.4 | -5.3 | 1.5e-07 | -0.88 | 0.02 | 0.95 | FALSE |
| 4 | GTEx | Brain Cortex | BID | 0.25 | 0.19 | lasso | 7 | 0.12 | 3.4e-04 | 5.4 | -5.7 | 1.6e-08 | -0.90 | 0.03 | 0.91 | FALSE |
| 5 | GTEx | Skin Sun Exposed Lower leg | BID | 0.19 | 0.15 | lasso | 5 | 0.15 | 1.4e-12 | 6.2 | -5.3 | 1.1e-07 | -0.97 | 0.00 | 1.00 | FALSE |
| 6 | METSIM | Adipose | ATP6V1E1 | 0.13 | 0.10 | lasso | 7 | 0.10 | 4.1e-14 | 4.2 | -5.2 | 2.1e-07 | -0.79 | 0.20 | 0.80 | FALSE |
| 7 | YFS | Blood | BCL2L13 | 0.08 | 0.07 | bslmm | 544 | 0.10 | 1.6e-30 | 5.4 | 6.5 | 1.1e-10 | 0.78 | 0.02 | 0.98 | TRUE |
| 8 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | BID | 0.16 | -0.01 | blup | 70 | 0.06 | 5.1e-03 | 5.3 | -5.4 | 7.1e-08 | -0.75 | 0.00 | 0.92 | FALSE |