Best TWAS P=5.13e-08 · Best GWAS P=2.74e-11 conditioned to 4.07e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FAM114A2 | 0.28 | 0.39 | lasso | 9 | 0.41 | 1.8e-53 | -4.8 | 5.2 | 2.5e-07 | 0.27 | 1.00 | 0.00 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | FAM114A2 | 0.05 | 0.06 | lasso | 6 | 0.05 | 6.3e-07 | -5.4 | 5.5 | 5.1e-08 | 0.25 | 0.94 | 0.05 | TRUE |
| 3 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | FAM114A2 | 0.07 | 0.06 | blup | 56 | 0.06 | 1.5e-03 | -4.8 | -5.1 | 2.9e-07 | -0.31 | 0.03 | 0.56 | FALSE |