[Hub]/) : Traits : Leg fat mass (left) :

chr8:22,687,572-24,094,711

Best TWAS P=8.16e-10 · Best GWAS P=7.57e-11 conditioned to 0.0163

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts SLC25A37 0.13 0.05 lasso 5 0.04 3.0e-04 -6.5 6.1 8.2e-10 -0.86 0.00 1.00 TRUE
2 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SLC25A37 0.11 0.09 lasso 5 0.09 7.8e-10 -4.9 -5.4 6.3e-08 0.59 0.92 0.08 FALSE
3 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma LOXL2 0.16 0.03 lasso 4 0.05 1.2e-03 -4.8 5.5 5.0e-08 -0.59 0.01 0.77 FALSE