TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Leg fat mass (left)
:
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chr8:22,687,572-24,094,711
Best TWAS P=8.16e-10 · Best GWAS P=7.57e-11 conditioned to 0.0163
22.8M
23M
23.2M
23.4M
23.6M
23.8M
24M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
SLC25A37
0.13
0.05
lasso
5
0.04
3.0e-04
-6.5
6.1
8.2e-10
-0.86
0.00
1.00
TRUE
3
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
LOXL2
0.16
0.03
lasso
4
0.05
1.2e-03
-4.8
5.5
5.0e-08
-0.59
0.01
0.77
FALSE
2
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
SLC25A37
0.11
0.09
lasso
5
0.09
7.8e-10
-4.9
-5.4
6.3e-08
0.59
0.92
0.08
FALSE