Best TWAS P=1.14e-10 · Best GWAS P=5.85e-13 conditioned to 0.000173
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | TEX15 | 0.05 | 0.03 | enet | 9 | 0.02 | 6.8e-04 | 5.4 | 6.4 | 1.1e-10 | 0.70 | 0.09 | 0.88 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | TEX15 | 0.05 | 0.04 | lasso | 4 | 0.04 | 2.7e-06 | 5.6 | 5.3 | 1.4e-07 | 0.66 | 0.56 | 0.43 | FALSE |