[Hub]/) : Traits : Leg fat mass (left) :

chr10:20,372,032-23,424,277

Best TWAS P=1.12e-20 · Best GWAS P=1.7e-22 conditioned to 0.0226

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex LOC100499489 0.06 0.00 bslmm 297 0.02 1.2e-03 0.89 -5.4 8.5e-08 -0.49 0.02 0.75 FALSE
2 CommonMind Brain Pre-frontal Cortex NEBL 0.07 0.01 blup 662 0.03 9.7e-05 -5.07 -6.4 1.7e-10 -0.03 0.76 0.01 TRUE
3 GTEx Artery Tibial CASC10 0.05 0.06 lasso 4 0.02 1.3e-02 3.90 6.1 1.1e-09 0.52 0.29 0.40 FALSE
4 GTEx Skin Sun Exposed Lower leg MLLT10 0.06 0.02 lasso 4 0.03 8.0e-04 9.09 -9.3 1.1e-20 -0.94 0.01 0.99 TRUE
5 GTEx Skin Sun Exposed Lower leg CASC10 0.08 0.02 lasso 5 0.01 6.1e-02 7.52 8.5 2.0e-17 0.90 0.10 0.79 FALSE
6 GTEx Spleen MLLT10 0.16 0.02 lasso 7 0.02 1.0e-01 7.52 -8.6 9.3e-18 -0.92 0.02 0.66 FALSE