[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr7:91,046,993-93,160,671

Best TWAS P=2.73e-50 · Best GWAS P=2.6e-46 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
28	GTEx	Testis	CDK6	0.10	0.10	lasso	3	0.09	8.0e-05	14.29	-14.9	2.7e-50	-0.96	0.00	0.99	TRUE
22	GTEx	Pituitary	KRIT1	0.21	-0.01	enet	14	0.20	1.1e-05	-0.12	-5.7	9.9e-09	-0.05	0.29	0.06	TRUE
1	CommonMind	Brain Pre-frontal Cortex	CDK6	0.12	0.10	lasso	2	0.10	1.9e-12	13.95	14.0	2.9e-44	0.89	0.03	0.97	FALSE
16	GTEx	Esophagus Muscularis	FAM133B	0.07	0.01	enet	2	0.01	1.2e-01	-9.74	-9.7	2.0e-22	-0.55	0.08	0.27	FALSE
12	GTEx	Cells Transformed fibroblasts	GATAD1	0.23	0.20	lasso	4	0.22	1.4e-16	6.97	-9.3	1.8e-20	-0.69	0.92	0.08	FALSE
34	YFS	Blood	GATAD1	0.01	0.01	blup	297	0.01	5.1e-04	6.97	-8.8	8.8e-19	-0.53	0.74	0.09	FALSE
10	GTEx	Brain Caudate basal ganglia	GATAD1	0.21	0.09	lasso	4	0.08	2.3e-03	5.69	-8.1	6.6e-16	-0.56	0.05	0.51	FALSE
4	GTEx	Adrenal Gland	GATAD1	0.40	0.22	lasso	7	0.25	2.0e-09	6.97	-7.9	2.6e-15	-0.57	0.61	0.16	FALSE
13	GTEx	Colon Transverse	GATAD1	0.13	0.00	enet	16	0.05	3.0e-03	6.97	-7.8	4.8e-15	-0.52	0.17	0.30	FALSE
24	GTEx	Skin Sun Exposed Lower leg	PEX1	0.18	0.06	enet	41	0.03	1.5e-03	-7.90	-7.7	1.5e-14	-0.44	0.21	0.14	FALSE
7	GTEx	Artery Coronary	GATAD1	0.12	0.15	lasso	3	0.12	8.0e-05	7.05	-7.3	3.7e-13	-0.54	0.17	0.28	FALSE
14	GTEx	Esophagus Mucosa	GATAD1	0.16	0.05	enet	16	0.08	7.3e-06	6.97	-7.2	6.5e-13	-0.46	0.68	0.21	FALSE
23	GTEx	Skin Not Sun Exposed Suprapubic	GATAD1	0.22	0.27	lasso	4	0.26	1.1e-14	6.97	-7.1	1.2e-12	-0.53	1.00	0.00	FALSE
26	GTEx	Spleen	PEX1	0.18	0.00	enet	38	0.05	2.4e-02	3.58	-7.0	3.2e-12	-0.38	0.08	0.13	FALSE
17	GTEx	Lung	GATAD1	0.15	0.12	lasso	2	0.11	1.1e-08	6.97	-6.9	4.4e-12	-0.53	0.99	0.00	FALSE
32	ROSMAP	Brain Pre-frontal Cortex	GATAD1	0.17	0.15	lasso	4	0.16	6.0e-20	6.92	-6.9	5.2e-12	-0.51	1.00	0.00	FALSE
6	GTEx	Artery Aorta	GATAD1	0.09	0.08	enet	4	0.07	7.4e-05	6.97	-6.9	6.6e-12	-0.49	0.49	0.11	FALSE
27	GTEx	Stomach	GATAD1	0.30	0.13	lasso	5	0.15	8.6e-08	6.97	-6.9	6.6e-12	-0.52	0.97	0.00	FALSE
3	GTEx	Adipose Visceral Omentum	GATAD1	0.12	0.08	lasso	5	0.06	7.5e-04	6.97	-6.8	9.3e-12	-0.51	0.80	0.08	FALSE
25	GTEx	Skin Sun Exposed Lower leg	GATAD1	0.30	0.10	enet	14	0.16	7.0e-13	6.97	-6.8	1.2e-11	-0.44	1.00	0.00	FALSE
31	ROSMAP	Brain Pre-frontal Cortex	KRIT1	0.04	0.03	bslmm	311	0.01	9.0e-03	3.58	6.8	1.5e-11	0.51	0.74	0.06	FALSE
19	GTEx	Muscle Skeletal	GATAD1	0.05	0.00	enet	13	0.01	2.4e-02	3.22	-6.7	2.6e-11	-0.44	0.46	0.07	FALSE
11	GTEx	Breast Mammary Tissue (Female)	AC007566.10	0.04	-0.01	lasso	2	0.01	2.0e-01	1.02	-6.7	2.9e-11	-0.32	0.03	0.16	FALSE
29	GTEx	Thyroid	GATAD1	0.18	0.06	lasso	4	0.06	3.3e-05	6.97	-6.7	2.9e-11	-0.48	0.96	0.02	FALSE
5	GTEx	Artery Aorta	KRIT1	0.15	0.00	enet	24	0.03	1.3e-02	0.12	-6.6	3.5e-11	-0.27	0.12	0.05	FALSE
8	GTEx	Artery Tibial	GATAD1	0.14	0.04	enet	17	0.04	4.1e-04	6.97	-6.6	5.3e-11	-0.45	0.69	0.12	FALSE
36	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GATAD1	0.04	0.04	lasso	2	0.03	2.8e-04	6.70	-6.5	1.1e-10	-0.47	0.14	0.21	FALSE
18	GTEx	Muscle Skeletal	PEX1	0.06	0.03	lasso	5	0.02	2.7e-03	5.97	6.4	1.5e-10	0.42	0.41	0.34	FALSE
35	The Cancer Genome Atlas	Breast Invasive Carcinoma	GATAD1	0.06	0.04	lasso	6	0.04	2.2e-09	6.70	-6.3	2.4e-10	-0.40	0.58	0.42	FALSE
21	GTEx	Pancreas	GATAD1	0.12	0.13	lasso	2	0.14	2.0e-06	6.97	-6.0	1.8e-09	-0.49	0.09	0.73	FALSE
15	GTEx	Esophagus Muscularis	GATAD1	0.18	0.10	enet	33	0.13	1.6e-08	6.97	-5.6	1.9e-08	-0.38	0.97	0.00	FALSE
37	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C7orf64	0.06	0.02	blup	36	0.02	6.0e-02	6.04	5.5	3.8e-08	0.42	0.04	0.05	FALSE
33	YFS	Blood	CYP51A1	0.03	0.06	blup	288	0.05	1.2e-16	3.92	-5.4	6.1e-08	-0.32	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	KRIT1	0.04	0.01	blup	318	0.02	1.2e-03	4.03	-5.3	1.2e-07	-0.20	0.60	0.02	FALSE
20	GTEx	Nerve Tibial	GATAD1	0.30	0.19	lasso	5	0.23	1.8e-16	6.97	-5.2	2.3e-07	-0.44	1.00	0.00	FALSE
9	GTEx	Artery Tibial	AC007566.10	0.13	0.04	lasso	5	0.00	3.1e-01	4.42	-5.2	2.4e-07	-0.10	0.08	0.04	FALSE
30	METSIM	Adipose	GATAD1	0.10	0.05	lasso	7	0.06	9.4e-10	3.22	-5.1	2.9e-07	-0.40	1.00	0.00	FALSE