Hub : Genes

KRIT1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0390	0.0220	0.00061	0.010	0.021	0.019	0.021	0.005	1.8e-02	0.00120	2.0e-03	0.0012	6.3e-02
2	GTEx	Artery Aorta	0.1520	0.0610	0.00016	0.003	NA	0.026	NA	0.006	2.1e-01	NA	1.3e-02	NA	1.4e-01
3	GTEx	Brain Cerebellum	0.1810	0.0890	0.00880	0.058	NA	0.055	NA	0.065	8.5e-03	NA	1.0e-02	NA	5.6e-03
4	GTEx	Colon Transverse	0.3220	0.1130	0.00100	-0.003	NA	-0.006	NA	-0.001	4.9e-01	NA	9.0e-01	NA	3.7e-01
5	GTEx	Esophagus Mucosa	0.0920	0.0460	0.00430	0.021	NA	0.000	NA	0.014	1.5e-02	NA	2.9e-01	NA	3.7e-02
6	GTEx	Nerve Tibial	0.1023	0.0542	0.00790	0.025	NA	0.019	NA	0.031	6.2e-03	NA	1.7e-02	NA	2.7e-03
7	GTEx	Pituitary	0.2100	0.0850	0.00110	-0.011	NA	0.198	NA	0.162	7.5e-01	NA	1.1e-05	NA	7.2e-05
8	METSIM	Adipose	0.0562	0.0419	0.00150	0.015	0.016	0.021	0.014	0.022	2.4e-03	0.00150	3.4e-04	0.0026	2.2e-04
9	ROSMAP	Brain Pre-frontal Cortex	0.0371	0.0190	0.00028	0.032	0.011	0.009	0.012	0.002	5.5e-05	0.01100	2.2e-02	0.0090	1.9e-01
10	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1790	0.0980	0.00360	0.010	0.060	0.067	NA	0.028	8.0e-02	0.00025	1.1e-04	NA	9.4e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Bipolar Disorder (2018)	0.7	1.0	2.9	1.3	1.1	-0.3	1.1	-0.6	-0.1	0.9	1.7	-1.2	0.7
Bipolar Disorder or Schizophrenia	0.4	1.1	2.9	-0.7	0.3	-1.7	-0.3	-1.4	-1.7	-0.5	0.8	-0.8	1.1
Depressed Affect (Nagel 2018)	0.4	0.8	2.0	1.3	1.0	0.8	0.3	0.7	1.1	1.4	-0.5	0.2	1.0
Depression (Nagel 2018)	0.8	1.3	3.9	0.5	0.4	-1.6	0.7	-2.0	-1.5	-0.2	-0.0	-1.4	-1.0
Intelligence (Savage-Jansen 2018)	0.1	0.4	0.7	-0.3	-0.7	0.6	-0.6	0.2	0.6	0.8	-0.8	0.6	0.8
Neuroticism (Nagel 2018)	0.2	0.4	1.8	0.1	-0.2	-0.2	-1.4	-0.3	-0.1	0.4	-1.1	0.4	-0.1
Schizophrenia (2018)	0.9	1.8	4.5	-1.9	-0.6	-1.9	-1.3	-1.3	-2.1	-1.4	-0.2	-0.1	0.8
Schizophrenia vs Biploar Disorder	2.3	3.0	7.4	-2.7	-1.3	-1.6	-2.7	-1.0	-1.3	-0.8	-1.4	1.5	-1.9
Worry (Nagel 2018)	0.2	0.4	1.2	-0.1	-0.7	-0.6	-1.0	-0.6	-0.5	0.6	-0.3	-0.3	-1.1
Alzheimer’s Disease (in mother)	4.0	4.7	7.9	2.8	2.0	2.2	2.3	2.7	2.1	1.9	1.9	-0.1	2.6
Alzheimer’s Disease (in father)	0.9	1.0	4.6	0.6	0.9	0.1	0.9	0.2	0.0	-1.1	2.1	-1.2	-0.6
Alzheimer’s Disease (including proxy)	5.0	7.2	12.9	3.6	3.4	2.7	2.7	3.0	2.7	1.5	3.0	-0.8	2.1
Crohns Disease (2017)	0.9	2.0	5.8	0.4	-0.6	-1.6	0.8	-1.6	-1.5	-0.9	2.2	-2.4	0.2
Irritable Bowel Disease (IBD)	0.7	1.6	4.2	2.1	1.4	0.8	1.4	1.0	0.9	0.8	1.9	-1.2	0.1
Ulcerative Colitis (UC)	0.8	1.5	3.4	1.6	1.9	1.4	0.6	1.7	1.4	1.0	0.5	0.2	-0.5
Major Depression (MDD)	1.2	1.4	5.0	0.9	0.7	-1.3	1.6	-1.3	-1.3	-0.7	0.1	-2.2	-0.1
Reaction Time	0.8	1.6	5.9	-1.6	-0.5	0.1	-1.6	0.5	0.1	0.2	-2.4	1.9	-0.9
Verbal and Numeric Reasoning (VNR)	0.2	0.5	1.0	-0.2	-0.1	0.9	-1.0	0.6	0.9	0.1	-0.8	0.7	0.9
Breast Cancer	6.5	15.6	39.3	6.3	4.7	2.5	5.2	2.9	1.9	3.3	2.2	-4.3	3.7
Ovarian Cancer	0.9	1.2	3.3	-0.2	-0.1	-1.2	-1.8	-0.6	-1.3	0.6	-1.8	-1.0	-0.2
Prostate Cancer	0.9	1.3	4.9	-0.9	-0.3	0.2	-1.6	0.7	0.3	-0.8	-2.2	1.7	-0.5
Age at First Birth	0.7	1.0	2.4	-1.6	-1.5	-0.7	-0.2	-0.5	-0.9	-0.7	-0.9	1.1	-0.9
Bipolar Disorder (2011)	0.1	0.1	0.7	-0.2	-0.3	-0.1	0.0	-0.4	-0.1	-0.5	0.9	-0.2	-0.1
Body Mass Index (BMI) (2010)	0.5	0.7	1.8	0.4	-0.1	1.4	-0.4	1.3	1.3	-0.1	-0.3	0.7	0.8
Coronary Artery Disease (CAD)	0.2	0.3	1.0	-0.6	0.5	-0.0	-1.0	0.3	-0.3	0.2	-0.4	0.3	-0.8
Crohns Disease (2012)	1.3	2.0	7.8	0.4	-0.7	-1.7	0.9	-1.7	-2.0	-1.0	0.0	-2.8	-0.4
Mean Putamen Volume	1.7	1.9	7.3	-1.6	-0.4	0.7	-2.0	0.6	0.2	0.5	-2.0	2.7	-0.0
Fasting Glucose	0.6	0.7	2.4	-0.3	-1.6	0.1	-0.2	-0.3	0.0	0.8	1.0	-0.2	1.6
HbA1C	0.5	0.5	1.4	0.2	0.4	1.0	0.7	0.5	1.2	0.8	0.6	-0.1	0.7
HDL Cholesterol	1.1	1.9	4.1	-1.3	-1.2	-1.9	-0.5	-2.0	-1.7	-1.7	0.0	-0.4	1.0
LDL Cholesterol	1.5	2.3	15.4	1.7	3.9	0.7	0.7	0.7	0.8	1.3	0.0	-1.0	0.6
Lupus	0.6	1.0	3.6	1.9	1.2	0.5	1.4	0.8	0.5	0.6	0.7	-0.6	-0.7
Neuroticism (2016)	1.7	2.5	11.0	1.8	0.6	-1.4	1.2	-1.2	-1.2	-2.0	0.0	-3.3	-0.1
Primary Biliary Cirrhosis	0.5	0.8	4.7	-0.5	-0.4	-0.6	-0.9	-0.6	-0.5	-2.2	-0.8	0.2	-0.1
Rheumatoid Arthritis	1.3	1.8	6.4	0.2	-0.2	1.7	0.9	1.5	1.6	0.9	1.4	2.5	0.8
Schizophrenia (2014)	0.5	1.1	3.0	-1.7	-0.4	-1.3	-1.5	-1.0	-1.3	-0.5	-0.1	0.7	0.3
Triglycerides	1.5	2.5	5.2	1.7	2.3	2.0	0.0	2.0	2.2	1.6	0.0	0.2	-0.8
Type 2 Diabetes (T2D) (2012)	0.8	0.9	2.7	-0.2	-0.6	1.4	-0.0	1.6	1.0	0.5	0.9	1.4	-0.5
Ulcerative Colitis	0.8	1.1	3.4	1.7	0.5	0.8	1.9	0.9	0.7	1.2	0.4	-0.8	-0.6
Blood Eosinophil Count	3.4	26.3	110.2	-7.8	-10.5	-3.9	-4.1	-4.3	-3.4	-2.5	0.0	4.7	-1.2
Blood Platelet Count	0.9	10.4	35.4	4.2	6.0	0.3	3.1	0.4	-0.1	1.7	2.6	-5.5	0.4
Blood Red Count	1.8	17.5	54.3	5.6	4.8	-0.3	7.0	-0.1	-0.2	3.6	2.0	-7.4	0.8
Blood White Count	1.1	8.5	51.8	0.8	-7.2	-1.1	3.1	-1.8	-0.6	0.9	2.5	-1.0	3.2
Heel T-Score	2.9	23.0	74.1	7.1	8.6	1.0	3.9	1.2	1.3	4.5	1.6	-7.8	1.4
BMI	0.1	0.8	3.2	-0.9	0.0	-0.9	0.1	-0.6	-0.9	-1.4	1.8	-0.3	0.2
Height	4.0	78.0	295.8	-10.6	-16.1	1.6	-2.6	1.1	1.6	-9.8	-1.5	17.2	0.8
Waist Hip Ratio (WHR)	0.5	2.2	3.8	-1.1	-0.0	-1.8	-1.7	-1.7	-1.9	-2.0	0.9	-1.8	-0.8
Systolic Blood Pressure	2.8	13.8	52.9	4.6	6.2	-2.3	2.9	-1.4	-2.0	1.7	-0.0	-7.3	-1.8
Smoking Status	0.8	2.0	6.4	0.5	0.5	1.7	0.1	1.7	1.8	1.6	0.8	2.5	0.7
Allergy or Eczema	0.6	1.6	4.6	-0.2	-1.1	-1.4	0.7	-1.2	-1.5	-1.4	2.1	-1.4	0.2
Cardiovascular Disease	1.2	4.1	18.1	1.7	4.2	-1.3	0.4	-0.8	-1.2	1.8	-0.0	-3.6	-0.5
Hypothyroidism (self reported)	0.4	1.0	4.1	-0.9	-0.9	-0.0	-0.1	-0.4	0.0	0.2	1.5	1.4	-2.0
Respiratory disease	0.3	0.7	3.5	-0.3	0.4	-0.8	1.1	-0.4	-0.8	-0.9	1.9	-0.0	0.1
Type 2 Diabetes (T2D) (2018)	1.9	3.6	8.1	2.3	2.9	0.9	2.3	1.2	0.7	1.3	2.8	-2.3	0.2
Lung FEV1/FVC ratio	0.2	0.9	3.6	0.5	0.8	0.3	0.3	0.8	-0.0	0.9	-1.6	-0.8	-1.9
Lung FVC	1.4	6.9	17.8	4.2	3.8	1.8	3.4	1.9	1.5	2.6	1.8	-2.4	0.7
Neuroticism	0.1	0.4	0.8	0.0	-0.6	-0.9	-0.9	-0.5	-0.7	0.8	-0.2	-0.4	-0.3
Chronotype (morning person)	1.7	4.0	9.6	2.3	1.9	0.3	3.1	0.2	0.5	0.8	3.0	-2.8	1.9
Hair Pigment	0.2	5.5	15.5	1.8	-0.2	-2.0	3.5	-2.4	-1.8	-1.2	1.9	-3.9	2.5
Tanning	0.1	1.2	7.5	1.2	0.3	0.8	0.5	0.4	0.7	0.7	2.7	-0.9	-0.1
Hand grip strength (left)	0.2	0.4	1.6	-0.0	-0.2	0.5	-0.4	0.4	0.6	-1.2	0.4	1.2	0.0
Number of treatments/medications taken	0.8	1.5	4.8	1.8	2.2	0.5	1.0	0.5	0.7	0.4	1.7	-1.3	0.5
Average weekly spirits intake	0.4	0.4	2.5	0.3	0.6	-0.1	0.9	-0.3	0.1	0.6	1.6	-0.4	-0.4
Sensitivity / hurt feelings	0.5	0.9	3.2	0.3	-0.1	-1.4	-0.6	-1.3	-1.1	-0.4	-0.8	-1.8	-0.2
Frequency of depressed mood in last 2 weeks	1.3	1.8	4.2	0.1	0.5	-2.1	1.3	-1.8	-1.9	-1.4	0.6	-1.3	-0.7
Hearing difficulty/problems: Yes	0.6	0.9	3.0	-1.1	-1.7	-0.7	-0.4	-0.6	-0.4	-0.4	-1.4	1.1	0.1
Relative age of first facial hair	0.5	1.1	3.2	-0.9	-1.3	0.8	-1.8	0.6	0.8	-0.6	-0.4	1.8	0.8
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	4.1	1.1	0.4	-0.0	2.0	-0.1	0.3	-0.3	0.5	-0.7	-0.7
Ever used hormone-replacement therapy (HRT)	2.4	3.0	10.9	2.0	0.4	-0.5	3.3	-0.3	-0.3	0.0	2.4	-2.7	1.5
Ever had hysterectomy (womb removed)	1.3	1.4	8.6	0.9	0.5	-0.8	1.4	-1.2	-0.7	0.1	-0.3	-2.9	-0.3
Systolic blood pressure, automated reading	3.6	10.6	42.8	3.2	5.1	-2.6	2.8	-1.9	-2.2	0.8	1.1	-6.5	-1.5
Eye problems/disorders: Diabetes related eye disease	1.1	1.3	3.9	2.0	1.2	0.7	1.2	0.6	0.9	1.1	0.9	-1.4	-0.4
Angina	0.8	1.1	3.2	1.3	0.0	-0.7	1.0	-0.2	-0.6	1.2	0.7	-1.6	1.8
Medication for hormone replacement therapy	4.8	5.4	15.8	2.9	2.0	1.6	4.0	2.3	1.5	1.6	3.5	-0.9	0.2
Vitamin and mineral supplements	0.5	0.7	2.5	-1.2	-0.5	-0.3	-1.3	-0.2	-0.0	-0.2	-1.6	0.1	-0.6
Supplements: Zinc	1.1	1.2	4.4	1.3	0.5	-0.7	2.1	-0.6	-0.9	0.8	0.8	-1.6	-0.4
Medication: Co-codamol	0.4	0.5	1.4	0.5	0.1	-0.5	0.8	-0.7	-0.5	0.5	1.2	-0.7	-0.7
Medication: Metformin	2.7	3.8	9.0	2.8	2.5	0.9	3.0	1.1	0.8	1.0	2.1	-2.3	1.0
Diabetes (father)	0.8	0.9	2.7	0.1	0.5	-0.4	0.2	0.3	-0.7	1.4	-1.6	-1.0	-1.6
Diabetes (mother)	0.8	1.1	3.9	1.0	0.5	0.6	0.5	0.3	0.8	1.3	0.9	-1.3	2.0
Severe depression (siblings)	0.7	0.8	3.7	0.9	0.5	0.6	1.3	0.3	0.4	0.3	1.9	-0.7	0.1
Pack years adult smoking proportion	0.3	0.5	2.0	-0.1	-0.4	-0.4	-0.7	-0.5	-0.4	-0.9	-0.7	0.3	-1.4
Impedance of leg (right)	0.2	1.2	3.6	1.3	1.9	-0.3	0.2	-0.4	-0.4	1.5	-0.6	-1.8	-0.5
Leg fat-free mass (left)	2.9	15.6	45.6	-5.3	-6.6	-0.3	-2.1	-0.5	-0.1	-5.7	0.7	6.8	0.4
Trunk fat percentage	0.4	1.7	5.6	-1.0	-2.1	-1.3	0.4	-1.4	-1.2	-2.4	0.6	-0.6	-0.0
Hand grip strength (right)	0.2	0.5	3.1	-0.3	-0.8	0.1	0.1	0.1	0.2	-1.8	0.2	1.1	-0.0
Townsend deprivation index at recruitment	0.5	0.7	1.9	-0.8	-0.9	-0.8	0.0	0.0	-0.6	-0.0	1.0	1.1	-1.4
Current tobacco smoking	0.4	0.6	1.6	0.5	0.0	0.8	0.6	0.7	1.0	1.2	0.7	1.1	-0.2
Average weekly fortified wine intake	0.5	0.6	1.3	0.6	0.4	1.0	1.1	0.9	0.8	-0.8	-0.0	0.7	0.4
Maternal smoking around birth	0.7	1.1	2.6	-1.4	-1.6	-1.4	-0.0	-1.0	-1.3	-1.2	0.5	0.0	0.0
Fed-up feelings	0.5	0.8	1.8	0.7	0.9	1.2	-0.7	0.9	1.2	0.4	-0.2	1.3	0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	2.0	-0.7	0.6	-0.8	-0.1	-1.1	-0.8	-0.9	0.5	0.5	-1.4
Relative age voice broke	0.5	0.8	2.2	-0.7	-1.3	-0.1	-1.2	-0.2	-0.1	-0.9	-0.2	1.1	1.5
Taking other prescription medications	1.5	2.3	8.2	-0.8	0.1	-1.2	0.6	-1.8	-1.0	-2.5	2.9	-0.6	1.3
Age when periods started (menarche)	0.2	0.5	2.0	-0.9	-0.5	-0.1	-0.5	-0.1	0.0	-0.4	-1.4	1.2	0.1
Bilateral oophorectomy (both ovaries removed)	3.1	3.6	16.4	2.8	0.7	-0.7	2.8	-0.8	-0.6	0.8	0.8	-4.1	0.7
Heel bone mineral density (BMD) T-score, automated (left)	1.3	2.9	11.6	2.7	2.2	-0.5	0.1	-0.3	-0.2	1.4	1.5	-3.4	-0.7
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	2.7	-1.3	-1.2	-0.7	0.1	-1.0	-0.5	-0.5	1.6	0.2	-0.6
Qualifications: CSEs or equivalent	1.9	2.5	4.9	-2.1	-1.6	-2.2	0.4	-2.0	-2.0	-1.7	1.2	0.1	-0.7
Serious illness, injury or assault to yourself	1.1	1.3	5.2	1.4	0.4	0.3	2.1	-0.1	0.4	-0.6	0.6	-2.3	0.3
High blood pressure	1.1	3.2	13.3	1.7	3.6	-0.7	1.6	-0.4	-0.4	1.0	-0.2	-3.2	-1.1
Hayfever, allergic rhinitis or eczema	0.4	0.9	3.4	-0.4	-1.1	-1.1	-0.2	-0.5	-1.3	-1.8	1.1	-0.5	0.1
Multivitamins +/- minerals	0.9	1.1	2.7	1.6	1.4	0.7	1.4	0.5	0.7	0.8	1.3	-0.2	0.9
Stomach or abdominal pain in last month	1.6	2.0	5.3	0.6	0.9	-1.8	1.3	-1.2	-2.0	-0.6	-1.4	-2.3	-0.9
Supplements: Glucosamine	0.4	0.5	2.2	1.1	0.8	0.0	1.5	-0.2	0.1	0.4	0.7	-0.3	-0.6
Diverticular disease/diverticulitis (self-reported)	0.7	0.9	2.7	1.4	1.1	0.2	1.5	0.1	0.2	-0.6	0.3	-1.6	0.2
Medication: Atenolol	0.1	0.1	0.6	0.3	0.2	-0.5	0.1	-0.8	-0.3	0.1	0.0	-0.5	-0.1
Medication: Levothyroxine sodium	1.6	2.8	7.7	-2.8	-2.0	-1.4	-1.8	-1.5	-1.1	-1.1	0.4	1.3	-1.9
Sitting height	2.5	17.7	72.8	-4.9	-7.2	1.5	-1.1	1.0	1.5	-4.7	-0.6	8.5	0.4
Chronic bronchitis/emphysema (father)	0.5	0.6	1.9	-0.7	-1.4	-0.7	-0.2	-1.1	-0.6	-0.0	0.5	0.1	-1.3
High blood pressure (mother)	0.5	0.6	1.8	-0.4	-0.0	-1.2	0.0	-1.1	-1.2	-0.6	0.3	-1.3	-0.0
Body mass index (BMI)	0.2	0.7	2.7	-0.8	-0.6	-0.6	-0.4	-0.8	-0.5	-1.3	1.6	-0.2	0.4
Impedance of leg (left)	0.4	1.7	5.5	1.8	2.0	-0.3	1.0	-0.4	-0.5	1.6	-0.5	-2.4	-0.4
Leg predicted mass (left)	3.0	15.9	45.7	-5.4	-6.7	-0.4	-2.1	-0.6	-0.1	-5.8	0.7	6.8	0.5
Trunk fat mass	0.9	4.1	14.4	-2.4	-3.8	-0.9	-0.2	-1.1	-0.8	-3.6	0.7	1.9	0.2
Waist circumference	0.7	2.7	7.8	-2.1	-2.6	-0.9	-0.8	-1.0	-0.7	-2.8	1.5	1.4	0.4
Number of incorrect matches in round	1.0	1.7	5.7	1.8	0.3	0.3	1.8	0.4	0.8	2.4	1.5	-1.2	-0.1
Past tobacco smoking	0.5	0.9	3.5	0.7	0.9	-0.8	0.9	-0.5	-1.0	0.6	-1.0	-1.9	-0.2
Alcohol usually taken with meals	1.3	2.1	8.7	0.6	0.6	-1.2	1.9	-1.7	-1.2	-0.6	0.5	-3.0	1.3
Nervous feelings	0.4	0.8	4.8	-0.7	-0.7	-0.6	-2.2	-0.5	-0.6	-0.2	-0.7	0.1	-0.9
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.6	0.4	-0.0	-0.7	0.2	-0.7	-0.8	-0.3	0.2	-0.3	-0.8
Hearing difficulty/problems with background noise	0.6	1.0	4.1	-0.8	-2.0	0.5	-0.1	0.9	0.8	0.4	-0.4	1.6	0.9
Hair/balding pattern: Pattern 2	1.5	1.9	8.4	-1.1	-0.5	-1.0	-1.7	-1.2	-1.2	-1.1	-0.8	0.2	-2.9
Had menopause	0.6	0.7	2.7	1.1	0.5	0.8	0.3	0.5	1.1	1.7	0.2	-0.7	0.5
Had other major operations	1.1	1.3	5.1	0.2	0.2	-1.1	1.1	-1.1	-1.2	-0.7	0.2	-2.3	1.5
Forced vital capacity (FVC)	0.4	1.7	4.3	0.3	-1.5	1.1	2.1	1.0	1.0	-1.1	1.0	2.0	0.9
Heel bone mineral density (BMD) T-score, automated (right)	1.6	3.7	17.9	2.7	2.4	-1.0	0.7	-0.6	-0.8	1.2	1.2	-4.2	-1.0
Ever unenthusiastic/disinterested for a whole week	3.4	4.2	14.0	2.7	1.3	0.7	3.3	0.7	0.7	1.0	3.7	-2.1	-1.0
Qualifications: None of the above	0.9	2.0	6.0	2.4	0.8	1.4	2.1	1.1	1.7	1.1	0.3	-0.4	1.2
Financial difficulties in last 2 years	3.9	5.3	13.5	3.2	3.7	1.5	3.4	1.5	1.5	0.8	2.4	-1.3	1.6
Mouth/teeth dental problems	0.9	1.4	11.6	0.6	0.2	-0.1	1.0	0.0	-0.2	0.3	0.1	-0.8	3.4
Heart attack	0.9	1.1	2.6	-0.3	0.4	-1.1	0.6	-1.1	-1.3	-1.6	0.4	-0.9	-1.6
Allergy	0.4	0.9	3.2	0.1	0.9	0.8	-0.9	0.2	1.0	1.8	-1.6	0.3	-0.5
Pain all over the body in last month	0.8	0.8	1.9	0.6	0.5	1.4	-0.1	1.3	1.4	0.7	-1.0	1.0	0.2
Diabetes (self-reported)	2.2	3.4	8.0	2.7	1.7	0.5	2.5	0.4	0.5	1.2	2.6	-2.8	0.5
Hayfever/allergic rhinitis (self-reported)	0.8	1.0	2.7	0.9	0.4	-0.5	0.9	-0.6	-0.4	-1.7	1.6	-1.4	0.5
Medication: Ramipril	0.3	0.4	1.0	-0.4	0.1	-0.5	0.5	-0.7	-0.7	-0.5	-0.8	-1.0	0.4
Medication: Simvastatin	0.3	0.5	2.8	0.9	0.6	-0.4	0.2	-0.3	-0.3	-0.5	0.1	-1.7	-0.4
Fluid intelligence score	0.5	1.0	2.6	-0.2	0.7	1.1	-1.6	0.7	1.1	-0.6	-1.3	1.3	0.8
Illnesses of siblings	1.3	1.8	5.4	-2.1	-2.2	-0.1	-0.8	0.1	-0.2	-1.5	-0.7	2.3	-0.3
Neuroticism score	0.2	0.4	0.9	0.4	-0.6	-0.9	-0.5	-1.0	-0.7	-0.1	0.7	-0.9	-0.2
Weight	1.8	8.6	27.2	-3.8	-5.2	-0.4	-1.0	-0.7	-0.2	-4.5	1.4	4.5	0.5
Impedance of arm (right)	0.1	0.4	2.3	0.6	0.1	0.1	0.4	0.1	-0.3	0.7	-1.5	-0.7	-0.4
Arm fat percentage (right)	0.3	1.2	3.1	-1.1	-1.1	-1.3	-0.2	-1.3	-1.3	-1.8	1.0	-0.8	0.4
Trunk fat-free mass	3.8	22.0	79.7	-6.2	-7.7	0.2	-2.6	-0.1	0.5	-5.8	0.7	8.9	1.0
Hip circumference	1.0	4.5	17.3	-2.6	-4.2	-0.1	-0.3	-0.4	0.1	-2.8	1.1	3.4	0.5
Time employed in main current job	0.6	0.7	1.3	0.2	0.6	1.1	-0.7	1.0	1.1	0.8	-0.3	1.1	-0.4
Alcohol intake versus 10 years previously	2.7	4.0	11.5	2.7	1.3	0.8	3.4	0.9	0.6	1.1	3.4	-1.7	1.5
Father’s age at death	0.4	0.6	1.8	1.4	0.6	0.2	1.2	0.3	0.5	0.1	1.0	-0.6	0.7
Worrier / anxious feelings	0.3	0.6	3.5	0.6	0.6	-0.4	-0.2	-0.3	-0.3	0.0	-0.3	-1.0	-1.9
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	4.0	-0.2	-0.8	-0.9	0.4	-1.6	-1.0	-2.0	-0.7	-0.6	0.2
Falls in the last year	0.9	1.2	5.8	0.8	-0.3	0.8	1.4	0.8	0.6	1.2	2.4	-0.5	0.5
Hair/balding pattern: Pattern 3	0.4	0.5	2.0	-0.7	-1.0	-0.3	-0.2	-1.2	-0.1	-0.0	1.4	-0.2	0.6
Number of live births	0.5	0.7	2.2	0.8	1.2	-0.1	0.9	0.7	0.2	1.5	-0.1	-1.1	0.7
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	3.2	0.3	-0.6	0.7	1.8	0.9	0.5	-0.7	0.5	1.1	0.0
Pulse rate	1.2	2.0	3.3	0.5	1.6	1.8	-0.1	1.6	1.8	1.4	1.8	1.0	1.2
Happiness	1.1	1.4	3.7	1.4	1.9	0.3	1.6	-0.0	0.2	1.8	1.1	-0.9	-0.3
Noisy workplace	1.2	1.4	3.5	0.6	-1.1	-1.3	1.9	-1.0	-1.3	-0.3	1.6	-1.5	-0.3
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.0	0.2	0.4	-0.5	0.0	-0.8	-0.8	-1.0	-0.6	-0.6	-0.7
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.2	4.1	2.0	1.6	1.0	1.1	1.1	0.7	1.0	-0.3	-0.8	0.1
Mouth/teeth dental problems: Dentures	1.7	2.8	5.8	2.4	1.6	1.8	1.9	1.5	2.0	1.1	2.0	-0.5	0.7
Asthma	0.7	1.4	6.1	0.6	0.7	0.4	2.0	0.8	0.2	-0.6	2.5	0.1	1.4
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.2	2.6	-1.5	-1.6	-1.3	-0.4	-1.4	-1.2	-0.1	-0.3	0.9	-0.8
Medication: Cholesterol lowering	0.5	0.8	2.6	1.6	1.4	-0.2	0.9	-0.3	-0.1	-0.4	0.6	-1.4	0.3
Depression (self-reported)	0.3	0.4	1.2	0.3	0.0	-0.4	0.0	-0.7	-0.7	-1.1	0.5	-0.9	-0.2
Medication: Lansoprazole	4.3	4.9	16.6	2.9	0.9	-0.2	3.7	-0.5	-0.1	0.4	1.8	-4.1	2.4
Prospective memory result	0.2	0.3	0.8	-0.1	-0.7	-0.1	-0.9	-0.4	-0.0	0.7	0.3	-0.4	-0.9
Lung cancer (father)	0.6	0.7	4.0	-0.7	-0.7	0.1	-1.0	0.3	0.0	-0.3	-0.3	2.0	-1.1
Illnesses of mother	0.3	0.4	1.3	-0.3	-0.1	0.3	-0.8	-0.2	0.3	-0.5	-0.4	1.1	-0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.8	2.1	0.6	-0.6	1.0	1.1	1.4	0.6	-0.7	0.3	1.4	0.4
Pulse wave Arterial Stiffness index	0.4	0.5	1.3	-0.7	-0.8	-0.2	0.4	-0.2	-0.2	-1.1	0.2	0.9	-1.0
Impedance of arm (left)	0.2	0.8	3.8	1.0	0.3	-0.4	0.7	-0.2	-0.7	0.5	-1.2	-1.9	-0.5
Arm fat mass (right)	0.8	3.2	9.5	-2.4	-3.0	-1.0	-0.7	-1.1	-0.9	-3.1	1.2	1.6	0.5
Trunk predicted mass	3.8	21.8	79.0	-6.2	-7.6	0.2	-2.6	-0.1	0.4	-5.8	0.7	8.9	1.0
Standing height	3.3	32.9	114.5	-6.8	-10.5	0.6	-1.5	0.2	0.7	-7.4	-0.2	10.7	0.5
Length of working week for main job	2.5	2.7	7.3	2.6	2.7	1.3	2.1	1.0	1.3	1.2	0.7	-1.6	-0.0
Exposure to tobacco smoke at home	0.6	0.6	2.3	0.4	0.7	0.8	-0.3	1.0	0.7	0.8	1.5	0.6	0.6
Breastfed as a baby	0.5	0.6	1.6	-0.2	-0.7	-1.0	0.6	-1.3	-0.9	-0.7	-0.6	-0.5	-0.4
Tense / ‘highly strung’	1.0	1.6	4.3	0.6	-2.0	-1.1	0.5	-1.2	-0.8	-0.6	1.9	-2.1	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	3.5	0.1	-0.8	-1.2	0.8	-1.4	-1.3	-0.8	1.0	-1.9	0.8
Hair/balding pattern: Pattern 4	0.5	1.2	2.8	1.6	1.6	0.3	1.2	0.7	0.6	1.0	0.3	-1.7	0.3
Birth weight of first child	0.5	0.8	3.0	-1.0	-0.3	0.3	-1.7	-0.1	0.6	-1.3	0.1	1.3	-0.5
Peak expiratory flow (PEF)	0.7	1.5	4.1	-0.1	-0.8	-1.6	2.0	-1.4	-1.5	-1.2	0.6	-1.4	-0.2
Pulse wave reflection index	0.9	1.1	3.0	-0.5	-1.1	-1.1	0.4	-1.3	-1.0	-1.1	-1.1	-0.4	-1.7
Ever highly irritable/argumentative for 2 days	1.6	1.9	9.7	1.8	0.0	1.0	1.0	0.6	0.9	1.6	3.1	-0.8	0.1
Loud music exposure frequency	2.0	2.2	4.8	-2.2	-1.8	-1.9	-0.8	-1.9	-1.8	-1.4	1.0	0.6	-0.2
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	4.0	-1.8	-0.6	-0.3	-2.0	-0.4	-0.5	-0.8	0.2	1.4	-0.4
Mouth/teeth dental problems: Bleeding gums	5.9	7.6	20.2	-3.3	-3.3	-2.1	-3.2	-2.1	-2.1	-2.1	-1.8	1.7	-4.5
Blood clot in the leg (DVT)	0.2	0.2	1.3	-0.3	-1.1	0.0	0.0	-0.0	0.3	0.5	-0.6	0.5	-0.3
Medication: Paracetamol	0.8	1.3	4.2	2.1	0.6	1.1	2.0	0.8	1.2	0.3	0.9	-0.1	0.2
Headache pain in last month	1.5	2.6	7.2	-1.5	-2.7	-1.8	-1.1	-2.4	-1.6	-1.3	0.9	-0.4	-1.4
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	4.0	-1.1	-2.0	0.0	-0.2	0.1	0.0	-0.5	0.4	1.1	-0.0
Glaucoma (self-reported)	1.2	1.5	3.8	-1.3	-1.3	-1.6	-0.7	-1.9	-1.5	-1.0	-0.8	-0.7	-0.3
Gout (self-reported)	0.6	0.8	2.0	-0.8	-0.9	-0.4	-1.4	-0.4	-0.4	-0.4	-0.7	1.3	-1.3
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	3.1	-1.4	-1.0	0.0	-0.8	-0.4	0.2	0.1	1.5	1.7	-1.7
Medication: Amlodipine	1.1	1.5	6.3	1.0	2.5	0.1	-0.7	0.4	0.3	1.7	-1.8	-0.6	-0.7
Medication: Ventolin 100micrograms inhaler	0.7	0.9	7.5	-0.8	0.4	-0.0	0.1	-0.3	0.1	-0.6	2.7	0.1	0.2
Birth weight	0.4	0.8	4.5	0.3	-1.2	-0.1	1.1	-0.2	-0.1	-2.1	0.4	0.3	0.3
Chronic bronchitis/emphysema (mother)	0.9	1.0	4.9	0.6	0.5	0.3	1.2	0.6	0.4	2.2	1.5	-0.5	0.4
High blood pressure (siblings)	0.6	0.8	2.8	1.4	1.2	-0.1	0.2	-0.3	-0.0	1.1	0.6	-1.7	0.4
Forced vital capacity (FVC), Best measure	0.4	1.5	4.8	0.1	-1.8	0.8	1.3	1.0	0.6	-1.5	0.5	2.2	1.0
Body fat percentage	0.3	1.0	2.8	-0.6	-1.1	-1.1	0.4	-1.2	-1.0	-1.7	1.1	-1.0	0.1
Leg fat percentage (right)	0.2	0.6	2.5	-0.2	0.4	-0.7	-0.0	-0.9	-0.6	-0.5	1.6	-1.2	0.2
Arm fat-free mass (right)	2.6	13.3	43.3	-4.7	-6.2	-0.1	-1.6	-0.4	0.3	-5.0	0.9	6.6	1.0
Exposure to tobacco smoke outside home	1.9	2.6	7.4	-0.5	-0.5	2.0	-1.7	1.8	2.2	1.6	-0.0	2.7	-0.1
Comparative body size at age 10	1.7	4.8	11.1	-3.2	-1.1	-1.7	-3.3	-1.7	-1.8	-3.0	-2.2	1.2	-0.8
Number of full brothers	0.5	0.6	1.9	-0.6	-0.1	-0.5	-1.4	-0.4	-0.5	-0.4	-1.2	0.8	-0.9
Worry too long after embarrassment	1.6	2.6	5.1	-1.6	-1.3	-1.8	-1.6	-1.7	-1.8	-2.2	-1.5	0.1	-1.9
Seen a psychiatrist for nerves, anxiety, tension or depression	2.2	2.9	9.5	3.1	1.8	1.0	2.4	0.7	0.9	1.5	1.2	-2.0	0.8
Wheeze or whistling in the chest in last year	0.9	1.6	8.2	-0.9	-0.5	-1.0	-0.1	-1.4	-0.6	-1.1	2.9	-0.7	-1.2
Number of children fathered	1.3	1.5	5.2	0.6	0.8	-0.9	0.6	-1.5	-0.8	-1.3	0.4	-1.5	-2.3
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.2	3.7	-0.8	0.3	1.0	-1.4	0.6	1.2	1.6	-0.2	1.9	-0.0
Age at first live birth	0.8	1.4	4.6	-1.8	-0.4	-0.3	-2.1	-0.6	-0.7	-0.6	-0.9	1.9	-0.9
Pulse wave peak to peak time	0.2	0.2	0.9	0.3	0.2	0.3	-0.6	0.2	0.3	0.8	-0.2	-0.1	1.0
Health satisfaction	0.4	0.5	2.5	0.1	0.7	0.1	0.3	-0.1	0.4	0.4	1.2	-0.6	1.6
Shortness of breath walking on level ground	0.2	0.2	0.9	-0.8	-0.3	0.3	0.1	0.3	0.6	0.2	1.0	0.5	0.1
Qualifications: College or University degree	0.8	2.6	5.1	-1.3	-0.6	-1.7	-0.7	-1.6	-1.9	-2.2	-2.2	-0.6	-2.0
Eye problems/disorders: None of the above	1.3	1.5	2.9	1.5	1.7	1.6	0.6	1.6	1.3	0.8	1.6	0.4	-0.2
Mouth/teeth dental problems: Loose teeth	0.2	0.3	2.3	0.4	0.3	0.1	-0.2	-0.0	0.3	0.3	-0.3	0.2	-1.5
Emphysema/chronic bronchitis	0.1	0.1	0.2	-0.1	-0.3	-0.1	0.4	-0.2	0.2	-0.4	-0.1	0.3	0.1
Medication for pain relief, constipation, heartburn	0.2	0.4	1.0	-0.9	-0.2	-0.2	-0.7	-0.4	-0.3	-0.2	-1.0	0.2	0.9
Neck or shoulder pain in last month	1.4	2.0	4.5	-1.2	-1.3	-2.1	0.4	-1.8	-2.1	-1.4	0.5	-0.7	-1.3
Medication: Blood pressure	0.6	1.1	5.3	0.9	2.3	0.6	-0.0	0.6	0.7	1.1	-1.5	-0.1	0.3
Angina (self-reported)	1.0	1.4	4.0	1.3	-0.1	-1.0	1.3	-0.6	-0.9	0.9	1.0	-2.0	1.5
Migraine (self-reported)	0.6	0.8	3.4	-0.8	-0.7	-0.9	0.6	-1.1	-0.6	-0.3	-1.8	0.1	-0.6
Medication: Ibuprofen	0.6	0.7	1.5	-1.0	-1.1	-1.0	-0.2	-1.2	-0.9	-0.2	0.3	0.6	-0.8
Medication: Allopurinol	0.3	0.4	1.4	-0.2	-0.4	-0.3	-0.9	-0.5	-0.2	-0.3	-0.8	0.8	-1.2
Medication: Omeprazole	1.6	1.9	5.8	-0.9	1.3	-1.5	-2.4	-1.4	-1.2	-1.0	0.2	-0.9	-1.9
Medication: Seretide 50 evohaler	1.9	2.2	7.1	2.4	1.0	0.8	2.7	0.3	0.9	-0.0	2.0	-1.7	0.6
Mean time to correctly identify matches	0.7	1.4	6.9	-1.5	-0.6	-0.2	-1.1	0.3	-0.2	0.5	-2.6	1.2	-1.1
Heart disease (mother)	0.6	0.8	3.8	0.0	-1.3	0.3	-0.8	0.3	-0.0	-0.0	-1.9	0.6	-1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	3.0	1.1	1.4	0.5	1.7	0.2	0.5	-0.2	1.3	-1.0	0.7
Whole body fat mass	0.8	3.5	11.2	-2.5	-3.4	-1.1	-0.4	-1.2	-0.9	-3.3	1.1	1.6	0.3
Leg fat mass (right)	0.6	2.2	6.7	-2.0	-2.1	-0.8	-0.6	-1.0	-0.7	-2.6	1.5	1.3	0.3
Arm predicted mass (right)	2.7	13.9	49.0	-4.7	-6.2	0.2	-1.8	-0.1	0.5	-5.0	0.5	7.0	0.8
Pulse rate, automated reading	0.5	1.8	7.0	-2.6	-0.7	-1.2	-2.0	-1.2	-1.1	-1.2	0.3	0.5	-0.5
Alcohol intake frequency.	0.9	2.0	8.2	1.7	0.8	-0.2	2.9	0.1	-0.0	-0.1	2.0	-1.6	1.1
Comparative height size at age 10	2.9	16.0	62.9	-4.6	-7.9	-0.6	-0.7	-0.6	-0.3	-5.3	1.0	6.6	-1.6
Number of full sisters	0.6	0.8	3.0	0.5	1.5	0.4	0.6	0.4	0.4	0.3	1.0	-0.4	1.7
Suffer from ‘nerves’	0.2	0.4	1.6	0.0	0.2	-0.1	-1.3	-0.1	-0.2	-0.5	0.9	0.9	-0.4
Overall health rating	0.5	1.0	3.2	1.8	1.3	-0.0	1.3	-0.1	0.3	-0.4	1.1	-1.4	-0.1
Chest pain or discomfort	0.8	1.2	4.4	-0.5	-1.5	-0.8	0.2	-1.0	-0.5	-1.3	2.1	-1.0	-0.6
Had major operations	1.2	1.4	5.4	1.1	0.3	-0.6	2.3	0.6	-0.9	-0.7	-1.0	-2.0	0.4
Age at last live birth	0.7	1.1	2.6	-1.5	-0.1	-1.3	-1.4	-1.2	-1.6	-0.5	-0.7	0.3	-0.2
Family relationship satisfaction	0.2	0.3	1.1	0.0	1.0	-0.4	-0.8	-0.4	-0.5	0.7	-0.0	-0.2	-0.2
Leg pain on walking	1.2	1.4	3.2	1.3	-0.1	1.3	1.3	1.0	1.3	1.6	1.8	0.3	0.8
Qualifications: NVQ or HND or HNC or equivalent	1.6	1.9	4.6	-2.1	-1.8	-1.6	-1.9	-1.4	-1.6	-0.1	0.5	0.1	-0.2
Commuting to job workplace: Car/motor vehicle	0.8	0.9	2.3	0.7	-0.4	-0.1	1.2	0.3	-0.2	1.5	1.5	-1.1	-0.9
Illness, injury, bereavement, stress in last 2 years	2.1	2.5	6.9	-2.6	-2.0	-1.4	-2.5	-1.5	-1.2	-0.7	-1.0	0.5	-0.8
Medication: Aspirin	0.8	1.0	3.5	1.9	1.0	0.6	0.3	1.0	0.8	0.8	0.7	-1.6	-0.0
Supplements: Vitamin C	1.7	2.0	6.1	0.4	-0.5	-1.6	1.9	-1.4	-1.4	-0.6	2.5	-1.5	1.2
Knee pain experienced in last month	1.6	2.4	6.9	-0.4	-2.3	-1.5	0.6	-2.6	-1.3	-0.4	1.3	-2.1	0.9
Hypertension (Self-reported)	1.3	3.6	12.8	1.4	3.4	-1.4	1.4	-1.0	-1.1	0.6	-0.6	-3.6	-1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.9	3.7	0.4	1.2	-0.6	0.4	-0.6	-0.4	-0.5	1.9	-1.4	-0.3
Illnesses of father: Heart disease	0.4	0.6	1.1	-0.6	1.0	-0.7	-1.0	-0.9	-0.6	0.5	-0.6	-0.4	1.0
Illnesses of siblings: Diabetes	2.8	3.4	8.7	2.3	2.1	0.1	2.4	-0.3	0.2	1.6	2.5	-2.9	1.0
Smoking status: Previous	0.4	0.5	2.0	0.1	0.1	0.9	-0.1	0.5	1.1	0.1	1.4	0.7	0.7
Forced expiratory volume in 1-second (FEV1), predicted	3.0	6.2	17.1	-3.7	-4.1	-1.0	-1.8	-1.1	-0.8	-3.4	-0.6	3.7	0.1
Whole body fat-free mass	3.5	19.9	65.0	-5.9	-7.5	-0.1	-2.2	-0.4	0.1	-6.1	0.7	8.1	0.8
Leg fat-free mass (right)	2.8	15.0	44.4	-5.1	-6.6	-0.2	-1.7	-0.4	0.0	-5.7	0.6	6.7	0.6
Arm fat percentage (left)	0.3	1.0	2.4	-0.8	-0.8	-1.2	-0.2	-1.2	-1.1	-1.6	1.0	-1.1	0.5
Average weekly red wine intake	0.3	0.4	2.6	0.3	1.6	0.2	0.0	0.3	-0.1	-0.3	-0.7	-0.6	-0.3
Handedness (chirality/laterality): Left-handed	0.2	0.3	1.1	-0.6	-0.3	0.1	-1.0	-0.3	-0.1	0.4	-0.1	0.2	1.0
Mood swings	0.1	0.2	0.6	0.1	0.3	-0.6	-0.3	-0.7	-0.3	-0.2	0.6	-0.8	0.4
Loneliness, isolation	1.6	2.2	7.7	2.0	1.6	0.3	2.1	0.9	0.6	0.3	1.3	-0.6	2.8
Long-standing illness, disability or infirmity	0.6	0.9	3.1	0.5	0.4	-0.4	1.4	-0.6	-0.2	-1.3	1.8	-0.7	0.6
Ever had bowel cancer screening	0.7	0.9	2.5	-0.2	-1.6	-1.1	-0.4	-1.5	-0.7	-0.8	-0.3	-0.9	-0.7
Diabetes diagnosed by doctor	2.4	4.0	8.9	3.0	2.4	1.2	2.6	1.4	1.0	1.5	2.4	-2.3	0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	2.9	0.0	-0.3	0.6	1.7	1.1	0.3	0.3	1.1	-0.1	-0.0
Friendships satisfaction	0.2	0.2	0.9	0.1	0.8	0.1	0.1	-0.1	-0.1	0.2	-0.4	0.1	1.0
Qualifications: nursing, teaching	0.1	0.2	0.6	-0.3	-0.0	0.4	0.3	0.3	0.4	0.8	0.1	0.5	-0.2
Commuting to job workplace: Walk	0.6	0.6	1.6	0.6	0.3	0.9	-0.4	0.8	0.9	0.2	-1.2	1.0	0.6
Eye problems/disorders: Cataract	0.2	0.2	0.7	0.0	-0.1	-0.2	0.2	-0.2	-0.2	0.4	-0.7	-0.6	0.8
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	7.3	-0.3	0.6	-0.7	-0.9	-0.1	-1.0	-0.0	0.1	-0.8	-2.7
Medication for cholesterol	1.8	2.7	13.1	-1.7	-1.6	1.3	-1.6	1.0	1.1	0.3	-1.2	3.6	0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.0	3.0	-1.7	-1.2	-0.2	-0.6	0.1	-0.3	-1.5	0.2	1.6	0.6
Back pain experienced in last month	0.9	1.3	5.7	0.3	-0.1	-1.0	1.3	-1.2	-0.9	-1.0	2.4	-0.9	-0.3
Mineral and other dietary supplements	0.2	0.2	0.6	-0.3	-0.6	0.6	-0.6	0.8	0.4	0.1	-0.1	0.3	0.5
Breast cancer (self-reported)	6.0	7.2	11.5	-3.4	-3.4	-2.6	-3.1	-2.7	-2.6	-3.2	-0.7	-0.2	-2.7
Asthma (self-reported)	0.8	1.6	6.4	0.6	0.8	0.7	1.9	1.0	0.5	-0.7	2.5	0.2	1.7
Osteoporosis (self-reported)	0.4	0.6	1.4	0.4	0.6	-0.8	-0.2	-0.7	-0.6	-1.1	-0.5	-0.8	-1.2
Osteoarthritis (self-reported)	0.5	0.6	1.6	0.7	1.2	0.4	0.8	0.2	0.7	0.8	0.3	-0.8	1.3
Medication: Aspirin	0.9	1.2	4.0	2.0	1.0	0.6	0.4	1.0	0.8	0.9	1.0	-1.8	0.2
Medication: Gliclazide	0.9	1.1	4.8	1.0	2.2	-0.4	0.6	0.4	-0.4	1.0	0.4	-1.0	-1.4
Illnesses of father: None of the above (group 1)	0.5	0.6	1.5	0.1	-1.2	0.5	1.2	0.9	0.3	-0.9	-0.0	1.0	0.3
Smoking status: Current	0.3	0.4	1.9	0.1	-0.4	0.5	-0.1	0.4	0.7	0.8	0.3	1.4	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.3	2.8	6.1	2.4	2.5	1.8	0.7	2.5	1.7	1.5	-0.3	-0.2	0.8
Whole body water mass	3.4	19.3	64.5	-5.8	-7.4	0.0	-2.3	-0.3	0.3	-5.8	0.6	8.0	0.7
Leg predicted mass (right)	2.8	15.2	45.0	-5.1	-6.7	-0.3	-1.7	-0.5	-0.1	-5.7	0.6	6.6	0.5
Arm fat mass (left)	0.7	2.8	8.8	-2.3	-3.0	-0.9	-0.7	-1.0	-0.8	-2.8	1.2	1.4	0.6
Number of self-reported non-cancer illnesses	1.2	2.2	5.0	0.6	1.2	-1.7	2.1	-1.7	-1.4	-0.8	1.3	-2.2	0.1
Average weekly champagne plus white wine intake	0.9	1.2	3.9	-2.0	-1.4	-1.1	-1.4	-0.8	-0.9	-0.6	-1.2	0.3	0.2
Miserableness	0.2	0.4	1.4	-0.4	-0.1	-0.6	-1.2	-0.8	-0.6	-0.4	-0.8	0.2	-0.1
Guilty feelings	2.4	3.6	10.6	-2.6	-1.5	-1.1	-3.3	-1.1	-0.8	-1.3	-2.1	2.2	-1.7
Wears glasses or contact lenses	1.3	1.5	4.3	-0.7	-0.1	1.2	-1.0	1.2	1.1	0.8	-1.6	2.1	1.3
Ever taken oral contraceptive pill	3.8	4.2	9.7	2.5	1.5	0.4	3.1	0.1	0.4	1.7	2.8	-2.7	2.2
Hearing aid user	0.8	0.9	1.9	0.4	1.3	0.7	1.1	1.4	0.6	1.1	-1.3	0.3	0.4
Mother’s age at death	0.2	0.2	1.1	0.0	-1.1	0.3	-0.4	-0.1	0.1	-0.4	-0.2	0.2	0.6
Financial situation satisfaction	0.9	1.2	3.6	1.2	1.9	0.4	1.6	0.5	0.4	1.7	0.7	-0.2	0.3
Tinnitus: Yes, now most or all of the time	2.1	2.4	8.2	2.1	0.4	1.1	1.4	0.3	1.0	1.9	2.9	-1.3	1.3
Commuting to job workplace: Public transport	1.8	2.1	3.9	0.5	1.2	2.0	-0.4	2.0	1.9	-0.3	-1.9	1.8	1.1
Eye problems/disorders: Glaucoma	1.9	2.3	6.1	-1.0	-1.6	-1.9	0.1	-2.5	-1.6	-0.4	-0.7	-2.4	0.8
Medication: Blood pressure	1.6	3.1	12.0	0.0	1.0	-2.5	0.3	-2.2	-2.0	-0.7	-0.2	-3.5	-1.6
Pain type(s) experienced in last month: Hip pain	2.4	3.1	9.4	2.3	1.9	-0.1	2.7	-0.2	-0.1	0.8	3.1	-2.0	0.3
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.3	1.1	0.9	0.2	0.8	-0.2	0.4	0.8	1.1	-0.4	-0.7
High cholesterol (Self-reported)	1.0	1.8	6.3	1.9	2.5	0.4	0.1	0.2	0.7	1.4	1.2	-1.6	0.9
Medication: Bendroflumethiazide	0.5	0.8	3.0	1.1	1.7	0.5	0.6	0.8	0.5	0.9	-0.4	-1.0	0.2
Medication: Paracetamol	1.2	1.9	6.1	2.5	1.1	0.9	2.0	0.7	1.2	0.5	2.0	-0.8	0.6
Medication: Lisinopril	0.3	0.4	1.2	-0.2	0.9	-0.6	-1.1	-0.8	-0.4	-0.3	0.1	-0.8	-0.5
Medication: Atorvastatin	0.5	0.6	2.3	0.8	1.5	0.1	-0.7	0.0	0.2	0.7	0.0	-1.2	-0.6
Illnesses of father: High blood pressure	1.0	1.3	3.1	-0.5	0.9	-1.8	-0.9	-1.8	-1.4	0.3	-0.7	-1.2	1.0
Alcohol drinker status: Never	1.2	1.4	4.1	-1.3	-0.8	-1.4	-0.7	-1.4	-1.4	-2.0	-1.2	0.2	-0.3
Ever smoked	0.7	1.2	4.2	-1.1	-1.4	0.1	-0.8	-0.1	0.3	-1.1	2.0	1.6	-0.6
Basal metabolic rate	3.1	17.4	53.1	-5.5	-7.1	-0.2	-2.0	-0.5	0.0	-5.8	0.9	7.3	0.7
Leg fat percentage (left)	0.2	0.6	2.8	-0.0	0.4	-0.6	0.3	-0.8	-0.6	-0.5	1.7	-1.3	0.2
Arm fat-free mass (left)	2.9	14.8	48.2	-5.2	-6.5	-0.2	-1.8	-0.5	0.1	-5.2	0.7	6.9	0.6
Number of operations (self-reported)	2.7	4.0	15.3	0.8	-0.7	-2.4	2.5	-1.6	-2.3	-1.7	-0.5	-3.9	0.7
Average weekly beer plus cider intake	0.6	0.8	2.1	0.5	0.4	1.1	-0.5	1.3	1.0	1.0	0.6	1.4	-0.5
Irritability	0.6	1.1	4.4	0.2	-1.2	-0.6	-0.9	-1.1	-0.6	-1.1	2.1	0.2	0.9
Risk taking	4.4	6.5	13.8	-0.6	-1.7	-2.7	3.1	-2.8	-2.9	-2.0	3.7	-3.2	0.6
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.0	-0.4	0.1	-0.4	-0.4	-0.4	-0.6	-0.7	0.4	-0.5	1.0
Fractured/broken bones in last 5 years	0.9	1.2	3.9	-1.0	-1.2	-0.5	-0.4	-0.5	-0.6	-1.1	0.8	1.6	-2.0
Age started oral contraceptive pill	0.7	0.9	2.4	1.1	0.3	1.1	0.7	1.1	1.0	1.6	-1.1	-0.0	0.1
Diastolic blood pressure, automated reading	1.1	3.4	10.2	-1.2	-0.2	-3.2	-0.0	-2.7	-2.8	-1.3	-0.9	-1.8	-1.1
Ever depressed for a whole week	2.3	2.9	10.1	2.4	0.9	-0.4	3.2	-0.1	-0.5	0.8	2.2	-2.5	0.2
Unable to work because of sickness or disability	0.9	1.1	2.5	1.3	1.0	1.6	0.1	0.9	1.6	0.9	0.5	1.0	0.9
Commuting to job workplace: Cycle	0.5	0.6	1.6	1.2	0.8	1.0	0.2	1.3	0.9	0.2	-0.2	-0.1	0.5
Myopia	1.6	2.3	6.6	1.6	0.6	2.3	0.9	2.6	2.1	1.1	-0.4	1.3	0.1
Vascular/heart problems diagnosed by doctor	1.0	2.7	10.7	-1.4	-2.8	1.1	-1.4	0.8	0.7	-0.6	0.2	3.3	1.4
Cholesterol lowering medication	0.8	1.2	5.7	0.7	0.9	-0.5	-0.4	-0.6	-0.3	1.2	1.4	-2.4	-0.9
Medication: Omeprazole (e.g. Zanprol)	1.7	2.0	3.9	-0.8	0.8	-1.9	-2.0	-1.9	-1.6	-1.3	0.4	-1.5	-1.2
Pain experienced in last month	1.3	2.2	5.2	0.3	1.8	1.7	-0.8	2.3	1.6	1.3	-1.9	1.4	0.9
Supplements: Calcium	0.7	0.8	2.9	0.7	0.7	1.1	-0.1	0.8	0.8	-0.8	1.7	0.9	-0.2
Basal cell carcinoma (self-reported)	1.9	2.3	7.6	-1.1	-2.2	-0.5	-1.6	-0.5	-0.6	-0.8	-2.8	1.5	-1.8
Heart attack/myocardial infarction (self-reported)	0.8	1.0	3.3	-0.4	0.3	-1.0	0.3	-1.2	-1.3	-1.8	0.0	-0.8	-1.3
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.9	0.3	-0.8	0.5	0.3	0.4	0.8	1.0	-0.4	0.2	-0.2
Heart disease (siblings)	0.6	0.8	2.7	0.2	0.6	-0.7	0.3	-1.6	-0.7	-0.9	0.7	-1.4	0.2
Alcohol drinker status: Previous	3.8	4.3	9.5	2.0	2.1	1.2	2.8	1.7	1.5	1.7	3.1	-0.9	2.8
Pack years of smoking	0.4	0.5	3.0	0.1	-0.4	-0.5	-0.6	-0.6	-0.3	-0.7	-0.8	0.1	-1.7
Impedance of whole body	0.3	1.6	6.5	1.7	1.1	-0.4	1.1	-0.3	-0.6	1.1	-1.3	-2.5	-0.5
Leg fat mass (left)	0.5	2.1	6.9	-1.8	-2.1	-0.6	-0.4	-0.8	-0.5	-2.6	1.6	1.3	0.5
Arm predicted mass (left)	2.9	14.6	47.7	-5.1	-6.5	-0.1	-1.7	-0.5	0.2	-5.1	0.7	6.9	0.8