[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr9:97,520,168-101,477,500

Best TWAS P=7.25e-16 · Best GWAS P=6.11e-19 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Artery Tibial	RP11-435O5.5	0.09	0.04	lasso	2	0.02	7.3e-03	8.25	-8.1	7.3e-16	-0.95	0.02	0.93	TRUE
22	The Cancer Genome Atlas	Stomach Adenocarcinoma	CDC14B	0.08	0.02	blup	41	0.04	1.0e-03	5.26	-7.1	1.3e-12	-0.08	0.03	0.54	TRUE
11	YFS	Blood	ANP32B	0.03	0.02	lasso	9	0.02	1.9e-08	-4.96	5.6	1.7e-08	0.00	0.00	0.99	TRUE
10	NTR	Blood	PTCH1	0.04	0.02	blup	433	0.02	4.1e-08	6.19	5.6	1.9e-08	0.09	0.07	0.92	TRUE
7	GTEx	Spleen	PTCH1	0.33	0.08	lasso	8	0.18	1.9e-05	-0.56	5.2	2.0e-07	0.28	0.11	0.44	TRUE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	PTCH1	0.02	0.01	blup	54	0.02	1.1e-03	7.03	-7.0	2.0e-12	-0.86	0.02	0.69	FALSE
13	YFS	Blood	PTCH1	0.09	0.05	lasso	8	0.05	1.2e-15	6.17	6.7	1.6e-11	0.42	0.13	0.87	FALSE
16	The Cancer Genome Atlas	Glioblastoma Multiforme	HABP4	0.08	0.06	blup	44	0.05	1.6e-02	5.87	-6.6	3.7e-11	-0.06	0.03	0.49	FALSE
17	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	HABP4	0.02	0.02	blup	44	0.02	7.1e-03	6.19	6.6	4.5e-11	0.04	0.04	0.55	FALSE
18	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CDC14B	0.03	0.02	blup	42	0.02	2.1e-03	6.19	-6.5	7.1e-11	-0.04	0.06	0.39	FALSE
14	The Cancer Genome Atlas	Breast Invasive Carcinoma	CDC14B	0.02	0.01	lasso	1	0.01	3.0e-03	6.47	-6.5	9.9e-11	-0.04	0.04	0.36	FALSE
8	GTEx	Testis	HABP4	0.19	0.22	lasso	9	0.21	1.1e-09	6.35	6.3	2.3e-10	0.04	0.14	0.86	FALSE
23	The Cancer Genome Atlas	Thyroid Carcinoma	CDC14B	0.05	0.07	blup	42	0.08	4.8e-08	6.26	-6.3	3.6e-10	-0.03	0.14	0.86	FALSE
9	GTEx	Thyroid	CDC14B	0.15	0.10	lasso	5	0.08	5.3e-07	5.98	-6.1	8.0e-10	-0.04	0.33	0.66	FALSE
12	YFS	Blood	HABP4	0.08	0.09	enet	24	0.11	5.9e-34	6.70	-5.9	2.8e-09	-0.09	0.02	0.98	FALSE
20	The Cancer Genome Atlas	Brain Lower Grade Glioma	HABP4	0.05	0.08	lasso	5	0.08	6.9e-09	5.79	-5.9	2.8e-09	-0.05	0.28	0.72	FALSE
6	GTEx	Nerve Tibial	ZNF367	0.10	0.05	lasso	3	0.02	7.9e-03	6.50	5.8	8.7e-09	0.04	0.08	0.89	FALSE
5	GTEx	Liver	PTCH1	0.25	0.06	enet	11	0.03	4.9e-02	8.60	5.7	1.3e-08	0.26	0.04	0.76	FALSE
15	The Cancer Genome Atlas	Glioblastoma Multiforme	CDC14B	0.16	0.17	blup	41	0.19	2.6e-06	6.19	-5.5	3.1e-08	-0.01	0.09	0.85	FALSE
1	CommonMind	Brain Pre-frontal Cortex	LOC441454	0.05	0.01	lasso	3	0.02	1.5e-03	5.26	5.5	3.3e-08	0.04	0.05	0.46	FALSE
4	GTEx	Cells EBV-transformed lymphocytes	AAED1	0.17	0.02	lasso	3	0.04	2.4e-02	6.19	5.4	5.2e-08	0.02	0.06	0.35	FALSE
19	The Cancer Genome Atlas	Brain Lower Grade Glioma	CDC14B	0.05	0.06	lasso	5	0.06	6.5e-07	6.15	-5.4	5.8e-08	-0.04	0.21	0.79	FALSE
3	GTEx	Breast Mammary Tissue	CDC14B	0.16	0.02	enet	21	0.02	3.7e-02	6.21	-5.3	1.0e-07	-0.02	0.14	0.71	FALSE