[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr10:69,348,758-70,981,217

Best TWAS P=8.66e-12 · Best GWAS P=1.47e-09 conditioned to 0.488

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
21	The Cancer Genome Atlas	Soft Tissue Sarcoma	SLC25A16	0.07	0.03	blup	42	0.02	1.7e-02	-6.0	-6.8	8.7e-12	0.92	0.01	0.93	TRUE
6	GTEx	Heart Atrial Appendage	PBLD	0.08	0.02	lasso	2	0.02	6.1e-02	-6.0	-6.6	5.4e-11	0.86	0.02	0.83	FALSE
14	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	DNA2	0.08	0.09	lasso	1	0.06	7.3e-04	-6.0	6.0	1.7e-09	-1.00	0.00	0.99	FALSE
20	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SLC25A16	0.02	0.02	enet	8	0.02	7.7e-04	-6.0	-5.9	3.6e-09	0.97	0.01	0.91	FALSE
13	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PBLD	0.06	0.07	lasso	2	0.04	2.3e-04	-5.7	-5.7	9.2e-09	0.47	0.00	1.00	FALSE
22	The Cancer Genome Atlas	Testicular Germ Cell Tumors	DNA2	0.14	0.07	blup	43	0.08	8.6e-04	-5.6	-5.5	3.4e-08	0.76	0.03	0.77	FALSE
19	The Cancer Genome Atlas	Brain Lower Grade Glioma	SLC25A16	0.05	0.01	blup	42	0.02	2.9e-03	-5.1	-5.5	4.0e-08	0.76	0.06	0.83	FALSE
17	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	ATOH7	0.08	0.04	enet	19	0.06	3.1e-04	-3.7	5.5	5.0e-08	-0.46	0.04	0.86	FALSE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PBLD	0.10	0.03	lasso	3	0.04	2.2e-05	-5.7	-5.4	6.6e-08	0.46	0.00	1.00	FALSE
8	GTEx	Pancreas	DNA2	0.12	0.06	enet	9	0.08	4.1e-04	-4.2	5.4	8.0e-08	-0.84	0.07	0.87	FALSE
18	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	DNA2	0.05	0.00	blup	43	0.00	3.0e-01	-5.1	5.4	8.0e-08	-0.86	0.01	0.84	FALSE
11	ROSMAP	Brain Pre-frontal Cortex	SLC25A16	0.17	0.11	lasso	6	0.15	2.9e-19	-4.2	-5.4	8.6e-08	0.90	0.13	0.87	FALSE
12	YFS	Blood	SLC25A16	0.09	0.13	lasso	3	0.13	6.8e-39	-5.0	-5.3	9.5e-08	0.89	0.09	0.91	FALSE
2	GTEx	Artery Coronary	DNA2	0.12	0.12	lasso	5	0.12	5.3e-05	-5.0	5.3	1.2e-07	-0.85	0.06	0.85	FALSE
15	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PBLD	0.03	0.03	lasso	9	0.02	1.6e-03	-5.2	-5.2	1.6e-07	0.51	0.02	0.86	FALSE
1	GTEx	Adipose Visceral Omentum	DNA2	0.32	0.18	lasso	9	0.20	1.9e-10	-5.1	5.2	1.7e-07	-0.81	0.60	0.40	FALSE
23	The Cancer Genome Atlas	Thyroid Carcinoma	SLC25A16	0.05	0.05	lasso	3	0.04	3.8e-05	-5.0	-5.2	1.7e-07	0.83	0.06	0.82	FALSE
9	GTEx	Skin Not Sun Exposed Suprapubic	DNA2	0.29	0.16	lasso	14	0.22	2.4e-12	-4.5	5.2	2.0e-07	-0.81	0.60	0.40	FALSE
5	GTEx	Cells Transformed fibroblasts	SLC25A16	0.10	0.02	enet	25	0.01	2.5e-02	-3.5	-5.2	2.1e-07	0.63	0.76	0.12	FALSE
10	ROSMAP	Brain Pre-frontal Cortex	PBLD	0.04	0.01	bslmm	388	0.02	1.3e-03	-3.7	-5.2	2.2e-07	0.64	0.16	0.83	FALSE
7	GTEx	Lung	DNA2	0.22	0.17	enet	12	0.24	3.9e-18	-5.0	5.2	2.3e-07	-0.80	0.61	0.39	FALSE
3	GTEx	Brain Hypothalamus	SLC25A16	0.20	0.19	lasso	5	0.14	3.6e-04	-5.1	-5.2	2.4e-07	0.83	0.10	0.37	FALSE
4	GTEx	Cells EBV-transformed lymphocytes	DNA2	0.32	0.14	lasso	2	0.10	2.9e-04	-5.1	5.1	3.1e-07	-0.84	0.09	0.81	FALSE