Best TWAS P=2.5e-08 · Best GWAS P=1.78e-06 conditioned to 0.355
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Liver | SYPL2 | 0.34 | 0.27 | lasso | 5 | 0.30 | 4.6e-09 | 4.5 | 5.3 | 1.4e-07 | 0.88 | 0.04 | 0.94 | FALSE |
2 | GTEx | Liver | ATXN7L2 | 0.39 | 0.04 | lasso | 12 | 0.21 | 1.3e-06 | 4.7 | 5.6 | 2.5e-08 | 0.75 | 0.04 | 0.84 | TRUE |