[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr11:71,619,100-73,149,098

Best TWAS P=1.58e-10 · Best GWAS P=4.96e-11 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	GTEx	Pituitary	RP11-169D4.2	0.19	0.20	lasso	2	0.16	7.3e-05	6.1	6.4	1.6e-10	0.98	0.00	0.97	TRUE
11	The Cancer Genome Atlas	Breast Invasive Carcinoma	PDE2A	0.02	0.02	lasso	2	0.02	2.0e-04	6.1	-6.1	9.6e-10	-0.94	0.02	0.91	FALSE
4	GTEx	Pituitary	PDE2A	0.25	0.19	lasso	5	0.17	4.1e-05	6.1	6.1	1.0e-09	0.94	0.00	0.96	FALSE
8	GTEx	Skin Not Sun Exposed Suprapubic	ARAP1-AS1	0.14	0.13	lasso	4	0.07	9.1e-05	5.7	5.8	8.2e-09	0.59	0.15	0.84	FALSE
6	GTEx	Skin Not Sun Exposed Suprapubic	ARAP1	0.24	0.20	lasso	4	0.16	3.6e-09	5.7	5.6	2.2e-08	0.55	0.16	0.84	FALSE
1	GTEx	Esophagus Mucosa	ARAP1	0.27	0.25	lasso	5	0.26	2.6e-17	5.7	5.5	3.0e-08	0.54	0.16	0.84	FALSE
2	GTEx	Esophagus Mucosa	ARAP1-AS2	0.12	0.08	lasso	6	0.08	3.1e-06	5.7	5.5	4.4e-08	0.53	0.14	0.75	FALSE
7	GTEx	Skin Not Sun Exposed Suprapubic	ARAP1-AS2	0.20	0.08	lasso	5	0.05	1.5e-03	4.0	5.5	4.4e-08	0.58	0.14	0.78	FALSE
9	GTEx	Skin Sun Exposed Lower leg	ARAP1	0.21	0.13	lasso	7	0.13	1.2e-10	5.7	5.3	9.2e-08	0.52	0.17	0.83	FALSE
10	GTEx	Skin Sun Exposed Lower leg	ARAP1-AS1	0.18	0.07	lasso	7	0.06	1.0e-05	5.7	5.3	1.1e-07	0.52	0.19	0.78	FALSE
3	GTEx	Esophagus Mucosa	ARAP1-AS1	0.15	0.12	enet	7	0.13	4.1e-09	5.7	5.3	1.2e-07	0.53	0.21	0.79	FALSE