Best TWAS P=1.87e-08 · Best GWAS P=2.14e-10 conditioned to 1.59e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | NFATC3 | 0.04 | 0.01 | lasso | 4 | 0.01 | 4.1e-02 | 5.3 | -5.6 | 1.9e-08 | -0.32 | 0.23 | 0.29 | TRUE |
| 2 | GTEx | Thyroid | PLA2G15 | 0.06 | 0.04 | enet | 5 | 0.04 | 5.7e-04 | 5.7 | 5.5 | 4.6e-08 | 0.38 | 0.21 | 0.72 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | NFATC3 | 0.11 | 0.04 | enet | 4 | 0.04 | 2.8e-05 | 5.4 | -5.3 | 1.5e-07 | -0.36 | 0.00 | 0.99 | FALSE |