Best TWAS P=4.23e-08 · Best GWAS P=5.91e-07 conditioned to 0.23
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Gastroesophageal Junction | RABEP1 | 0.19 | -0.01 | lasso | 13 | 0.00 | 4.2e-01 | 4.1 | -5.2 | 1.5e-07 | -0.82 | 0.03 | 0.68 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | RPAIN | 0.06 | 0.06 | lasso | 3 | 0.06 | 3.1e-08 | 5.0 | -5.2 | 2.1e-07 | -0.98 | 0.00 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Glioblastoma Multiforme | RABEP1 | 0.23 | 0.13 | blup | 79 | 0.15 | 3.4e-05 | 4.2 | -5.5 | 4.2e-08 | -0.77 | 0.04 | 0.77 | TRUE |