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Leg fat-free mass (left)
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chr18:56,399,379-58,729,694
Best TWAS P=3.19e-35 · Best GWAS P=1.83e-122 conditioned to 2.32e-83
56.5M
57M
57.5M
58M
58.5M
0
20
40
60
80
100
120
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
MC4R
0.10
0.02
blup
455
0.04
6.7e-06
17.9
-12.4
3.2e-35
-0.59
0.22
0.66
TRUE
2
METSIM
Adipose
CCBE1
0.07
0.00
blup
788
0.03
1.2e-05
1.6
-5.4
5.9e-08
-0.22
0.47
0.02
TRUE