TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Leg fat-free mass (left)
:
←
→
chr1:15,752,716-16,844,848
Best TWAS P=5.12e-08 · Best GWAS P=4.98e-07 conditioned to 0.666
15.8M
16M
16.2M
16.4M
16.6M
16.8M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Nerve Tibial
EPHA2
0.19
0.13
enet
29
0.14
6.7e-10
5
-5.5
5.1e-08
-0.89
0.01
0.99
TRUE
2
GTEx
Thyroid
EPHA2
0.10
0.05
lasso
9
0.06
1.7e-05
5
-5.2
2.4e-07
-0.83
0.01
0.98
FALSE