[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr3:55,969,663-58,283,722

Best TWAS P=2.14e-11 · Best GWAS P=5.42e-11 conditioned to 0.0123

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	The Cancer Genome Atlas	Lung Adenocarcinoma	CCDC66	0.05	0.06	blup	56	0.05	9.7e-07	-6.1	-6.7	2.1e-11	0.73	0.00	0.99	TRUE
2	GTEx	Adrenal Gland	RP11-755B10.4	0.11	0.06	lasso	11	0.04	1.4e-02	5.4	-5.4	7.3e-08	-0.01	0.03	0.90	TRUE
6	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CCDC66	0.05	0.05	blup	56	0.06	1.0e-07	-6.0	-6.7	2.7e-11	0.79	0.01	0.99	FALSE
4	GTEx	Cells Transformed fibroblasts	FAM208A	0.10	0.00	lasso	4	0.00	1.3e-01	-6.1	5.7	9.0e-09	-0.82	0.04	0.89	FALSE
7	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C3orf63	0.03	0.01	enet	4	0.01	1.3e-02	-6.0	5.6	2.0e-08	-0.89	0.01	0.85	FALSE
5	The Cancer Genome Atlas	Breast Invasive Carcinoma	CCDC66	0.09	0.03	lasso	8	0.05	4.2e-11	-3.8	-5.4	5.4e-08	0.54	0.43	0.57	FALSE
10	The Cancer Genome Atlas	Stomach Adenocarcinoma	CCDC66	0.05	0.01	blup	57	0.02	8.4e-03	-3.8	-5.4	6.0e-08	0.55	0.10	0.35	FALSE
9	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CCDC66	0.03	0.03	blup	56	0.03	9.6e-05	-4.6	-5.3	9.2e-08	0.51	0.36	0.22	FALSE
1	GTEx	Adipose Subcutaneous	FAM208A	0.12	0.09	enet	11	0.12	1.1e-09	-3.7	5.3	1.1e-07	-0.82	0.06	0.94	FALSE
3	GTEx	Artery Tibial	RP11-755B10.4	0.11	0.06	enet	13	0.04	2.1e-04	5.3	-5.2	1.8e-07	-0.06	0.02	0.97	FALSE