[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr3:55,969,663-58,283,722

Best TWAS P=2.14e-11 · Best GWAS P=5.42e-11 conditioned to 0.0123

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous FAM208A 0.12 0.09 enet 11 0.12 1.1e-09 -3.7 5.3 1.1e-07 -0.82 0.06 0.94 FALSE
2 GTEx Adrenal Gland RP11-755B10.4 0.11 0.06 lasso 11 0.04 1.4e-02 5.4 -5.4 7.3e-08 -0.01 0.03 0.90 TRUE
3 GTEx Artery Tibial RP11-755B10.4 0.11 0.06 enet 13 0.04 2.1e-04 5.3 -5.2 1.8e-07 -0.06 0.02 0.97 FALSE
4 GTEx Cells Transformed fibroblasts FAM208A 0.10 0.00 lasso 4 0.00 1.3e-01 -6.1 5.7 9.0e-09 -0.82 0.04 0.89 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma CCDC66 0.09 0.03 lasso 8 0.05 4.2e-11 -3.8 -5.4 5.4e-08 0.54 0.43 0.57 FALSE
6 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CCDC66 0.05 0.05 blup 56 0.06 1.0e-07 -6.0 -6.7 2.7e-11 0.79 0.01 0.99 FALSE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C3orf63 0.03 0.01 enet 4 0.01 1.3e-02 -6.0 5.6 2.0e-08 -0.89 0.01 0.85 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma CCDC66 0.05 0.06 blup 56 0.05 9.7e-07 -6.1 -6.7 2.1e-11 0.73 0.00 0.99 TRUE
9 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CCDC66 0.03 0.03 blup 56 0.03 9.6e-05 -4.6 -5.3 9.2e-08 0.51 0.36 0.22 FALSE
10 The Cancer Genome Atlas Stomach Adenocarcinoma CCDC66 0.05 0.01 blup 57 0.02 8.4e-03 -3.8 -5.4 6.0e-08 0.55 0.10 0.35 FALSE