[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr3:153,142,317-154,733,231

Best TWAS P=1.03e-12 · Best GWAS P=9.17e-12 conditioned to 0.0326

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Ovary	ARHGEF26	0.14	0.03	enet	15	0.06	1.4e-02	6.7	7.1	1.0e-12	-0.76	0.04	0.70	TRUE
5	GTEx	Pancreas	ARHGEF26	0.26	0.26	lasso	5	0.28	3.2e-12	-6.0	7.0	1.8e-12	-0.73	0.26	0.74	FALSE
12	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SGEF	0.04	0.04	enet	12	0.04	1.1e-05	-5.9	6.9	6.4e-12	-0.77	0.08	0.89	FALSE
6	GTEx	Skin Not Sun Exposed Suprapubic	ARHGEF26	0.13	0.11	lasso	4	0.07	6.8e-05	-6.0	6.7	2.6e-11	-0.70	0.22	0.77	FALSE
1	CommonMind	Brain Pre-frontal Cortex	DHX36	0.05	0.06	blup	357	0.05	1.3e-06	-6.1	-6.4	1.8e-10	0.66	0.31	0.69	FALSE
9	GTEx	Thyroid	ARHGEF26	0.09	0.07	enet	17	0.08	1.9e-06	-6.2	6.3	3.1e-10	-0.62	0.24	0.74	FALSE
2	GTEx	Adipose Subcutaneous	ARHGEF26	0.10	0.06	enet	8	0.07	2.2e-06	-6.2	6.3	3.9e-10	-0.61	0.24	0.76	FALSE
11	METSIM	Adipose	ARHGEF26	0.07	0.08	lasso	6	0.07	3.5e-11	-6.1	6.2	4.5e-10	-0.55	0.31	0.69	FALSE
7	GTEx	Skin Sun Exposed Lower leg	ARHGEF26	0.10	0.08	enet	12	0.11	2.9e-09	-6.1	5.9	3.0e-09	-0.50	0.34	0.66	FALSE
3	GTEx	Artery Tibial	ARHGEF26	0.11	0.12	enet	12	0.12	5.9e-10	-6.1	5.7	1.1e-08	-0.54	0.32	0.68	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	DHX36	0.11	0.09	enet	11	0.10	6.4e-12	-5.4	-5.7	1.4e-08	0.48	0.90	0.10	FALSE
10	GTEx	Thyroid	DHX36	0.06	0.01	lasso	4	0.02	1.7e-02	-5.6	-5.4	7.7e-08	0.49	0.23	0.40	FALSE
8	GTEx	Spleen	DHX36	0.39	0.09	enet	21	0.34	2.1e-09	-3.4	-5.3	1.1e-07	0.66	0.35	0.60	FALSE
14	The Cancer Genome Atlas	Thyroid Carcinoma	DHX36	0.16	0.17	blup	50	0.19	7.7e-18	-3.4	-5.2	2.5e-07	0.57	0.99	0.01	FALSE