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Traits
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Traits
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Leg fat-free mass (left)
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chr3:171,064,766-172,924,003
Best TWAS P=2.46e-14 · Best GWAS P=2.56e-17 conditioned to 5.27e-10
171M
171.5M
172M
172.5M
173M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
FNDC3B
0.07
0.06
enet
8
0.05
3.2e-07
-8.0
7.6
2.5e-14
0.04
0.09
0.91
TRUE
2
YFS
Blood
TNFSF10
0.09
0.04
bslmm
462
0.08
1.6e-24
5.9
6.4
1.3e-10
0.38
1.00
0.00
TRUE
3
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
FNDC3B
0.07
0.02
enet
6
0.02
3.9e-03
5.5
-5.9
4.3e-09
-0.83
0.01
0.98
FALSE