[Hub]/) : Traits : Leg fat-free mass (left) :

chr3:195,279,119-196,855,644

Best TWAS P=2.25e-10 · Best GWAS P=4.87e-08 conditioned to 0.288

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial SLC51A 0.28 0.17 lasso 9 0.21 4.3e-16 4.9 -5.3 1.4e-07 -0.86 0.02 0.98 FALSE
2 GTEx Breast Mammary Tissue PCYT1A 0.11 0.03 lasso 3 0.00 3.9e-01 5.5 -5.4 6.9e-08 -0.96 0.01 0.90 FALSE
3 GTEx Breast Mammary Tissue SLC51A 0.28 0.06 lasso 6 0.14 1.3e-07 3.8 -6.3 3.1e-10 -0.58 0.02 0.97 FALSE
4 GTEx Breast Mammary Tissue UBXN7 0.20 0.00 enet 16 0.02 3.5e-02 -4.2 -5.5 3.7e-08 -0.65 0.03 0.86 FALSE
5 GTEx Breast Mammary Tissue (Male) UBXN7 0.22 -0.01 lasso 4 0.01 1.6e-01 -5.3 -5.2 1.9e-07 -0.52 0.02 0.53 FALSE
6 GTEx Cells Transformed fibroblasts SLC51A 0.30 0.22 lasso 4 0.24 5.0e-18 3.8 -5.3 1.3e-07 -0.66 0.58 0.35 FALSE
7 GTEx Heart Atrial Appendage SLC51A 0.27 0.11 lasso 4 0.15 2.9e-07 3.8 -5.4 5.2e-08 -0.70 0.03 0.96 FALSE
8 GTEx Nerve Tibial SLC51A 0.26 0.12 lasso 7 0.22 1.9e-15 3.8 -5.4 7.1e-08 -0.73 0.04 0.95 FALSE
9 GTEx Stomach SLC51A 0.13 0.06 enet 12 0.03 1.9e-02 4.9 -5.6 1.7e-08 -0.86 0.01 0.96 FALSE
10 GTEx Thyroid SLC51A 0.17 0.06 enet 17 0.06 1.9e-05 4.9 -5.2 2.3e-07 -0.78 0.02 0.97 FALSE
11 The Cancer Genome Atlas Soft Tissue Sarcoma PCYT1A 0.12 0.05 blup 68 0.06 2.0e-04 4.9 -6.3 2.2e-10 -0.75 0.01 0.90 TRUE