[Hub]/) : Traits : Leg fat-free mass (left) :

chr4:305,291-2,437,290

Best TWAS P=1.07e-11 · Best GWAS P=5.35e-13 conditioned to 0.000174

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CRIPAK 0.31 0.15 enet 34 0.26 1.2e-31 -3.10 -5.3 9.9e-08 0.04 1.00 0.00 FALSE
2 GTEx Brain Cortex CRIPAK 0.34 0.10 lasso 6 0.18 9.5e-06 -4.12 -5.8 7.5e-09 0.03 0.19 0.10 FALSE
3 GTEx Brain Hippocampus CRIPAK 0.48 0.22 lasso 4 0.23 4.0e-06 -3.46 -5.9 3.9e-09 0.00 0.18 0.14 FALSE
4 GTEx Brain Putamen basal ganglia CRIPAK 0.30 0.00 enet 25 0.10 1.9e-03 -3.03 -5.1 2.9e-07 0.11 0.06 0.10 FALSE
5 GTEx Breast Mammary Tissue (Female) CRIPAK 0.32 0.17 enet 29 0.26 2.7e-08 -3.05 -5.6 1.8e-08 0.01 0.53 0.03 FALSE
6 GTEx Colon Transverse TMEM129 0.23 0.05 lasso 4 0.03 1.8e-02 -5.18 5.8 6.6e-09 0.51 0.09 0.09 FALSE
7 GTEx Lung CRIPAK 0.61 0.22 enet 46 0.41 1.1e-33 -4.12 -6.3 3.8e-10 0.02 1.00 0.00 FALSE
8 GTEx Muscle Skeletal FGFRL1 0.14 0.08 lasso 4 0.06 3.7e-06 -6.67 6.1 1.1e-09 0.01 0.00 1.00 TRUE
9 GTEx Muscle Skeletal CRIPAK 0.25 0.11 enet 32 0.18 7.6e-18 -4.12 -5.3 1.1e-07 0.03 1.00 0.00 FALSE
10 GTEx Nerve Tibial CRIPAK 0.50 0.11 enet 76 0.38 1.1e-28 -3.46 -6.2 7.8e-10 -0.08 1.00 0.00 FALSE
11 GTEx Ovary CRIPAK 0.43 0.27 enet 19 0.32 9.0e-09 -4.12 -5.3 1.0e-07 0.03 0.46 0.06 FALSE
12 GTEx Whole Blood CRIPAK 0.38 0.17 lasso 9 0.28 3.4e-26 -3.46 -5.2 1.5e-07 0.02 1.00 0.00 FALSE
13 METSIM Adipose CRIPAK 0.28 0.16 bslmm 335 0.25 2.7e-37 -3.24 -6.2 4.7e-10 -0.01 1.00 0.00 FALSE
14 METSIM Adipose UVSSA 0.26 0.04 bslmm 366 0.12 9.0e-18 0.86 -5.5 3.5e-08 0.02 0.98 0.02 FALSE
15 NTR Blood CRIPAK 0.13 0.09 enet 31 0.15 1.5e-46 -2.93 -6.8 1.1e-11 0.00 1.00 0.00 TRUE
16 NTR Blood KIAA1530 0.19 0.04 blup 345 0.10 9.1e-32 -3.62 -6.4 2.0e-10 0.08 1.00 0.00 FALSE
17 NTR Blood SLBP 0.04 0.02 lasso 5 0.02 2.8e-08 -5.31 6.1 8.0e-10 0.82 0.03 0.97 TRUE
18 NTR Blood TACC3 0.05 0.03 lasso 9 0.04 2.7e-13 -5.12 6.1 1.2e-09 0.71 0.50 0.50 FALSE
19 YFS Blood CRIPAK 0.35 0.27 bslmm 301 0.33 6.0e-112 -3.46 -5.4 5.7e-08 -0.03 1.00 0.00 FALSE
20 The Cancer Genome Atlas Breast Invasive Carcinoma CRIPAK 0.22 0.11 blup 28 0.14 5.6e-28 -3.46 -5.5 3.9e-08 0.01 0.00 0.32 FALSE