[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr4:305,291-2,437,290

Best TWAS P=1.07e-11 · Best GWAS P=5.35e-13 conditioned to 0.000174

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
15	NTR	Blood	CRIPAK	0.13	0.09	enet	31	0.15	1.5e-46	-2.93	-6.8	1.1e-11	0.00	1.00	0.00	TRUE
17	NTR	Blood	SLBP	0.04	0.02	lasso	5	0.02	2.8e-08	-5.31	6.1	8.0e-10	0.82	0.03	0.97	TRUE
8	GTEx	Muscle Skeletal	FGFRL1	0.14	0.08	lasso	4	0.06	3.7e-06	-6.67	6.1	1.1e-09	0.01	0.00	1.00	TRUE
16	NTR	Blood	KIAA1530	0.19	0.04	blup	345	0.10	9.1e-32	-3.62	-6.4	2.0e-10	0.08	1.00	0.00	FALSE
7	GTEx	Lung	CRIPAK	0.61	0.22	enet	46	0.41	1.1e-33	-4.12	-6.3	3.8e-10	0.02	1.00	0.00	FALSE
13	METSIM	Adipose	CRIPAK	0.28	0.16	bslmm	335	0.25	2.7e-37	-3.24	-6.2	4.7e-10	-0.01	1.00	0.00	FALSE
10	GTEx	Nerve Tibial	CRIPAK	0.50	0.11	enet	76	0.38	1.1e-28	-3.46	-6.2	7.8e-10	-0.08	1.00	0.00	FALSE
18	NTR	Blood	TACC3	0.05	0.03	lasso	9	0.04	2.7e-13	-5.12	6.1	1.2e-09	0.71	0.50	0.50	FALSE
3	GTEx	Brain Hippocampus	CRIPAK	0.48	0.22	lasso	4	0.23	4.0e-06	-3.46	-5.9	3.9e-09	0.00	0.18	0.14	FALSE
6	GTEx	Colon Transverse	TMEM129	0.23	0.05	lasso	4	0.03	1.8e-02	-5.18	5.8	6.6e-09	0.51	0.09	0.09	FALSE
2	GTEx	Brain Cortex	CRIPAK	0.34	0.10	lasso	6	0.18	9.5e-06	-4.12	-5.8	7.5e-09	0.03	0.19	0.10	FALSE
5	GTEx	Breast Mammary Tissue (Female)	CRIPAK	0.32	0.17	enet	29	0.26	2.7e-08	-3.05	-5.6	1.8e-08	0.01	0.53	0.03	FALSE
14	METSIM	Adipose	UVSSA	0.26	0.04	bslmm	366	0.12	9.0e-18	0.86	-5.5	3.5e-08	0.02	0.98	0.02	FALSE
20	The Cancer Genome Atlas	Breast Invasive Carcinoma	CRIPAK	0.22	0.11	blup	28	0.14	5.6e-28	-3.46	-5.5	3.9e-08	0.01	0.00	0.32	FALSE
19	YFS	Blood	CRIPAK	0.35	0.27	bslmm	301	0.33	6.0e-112	-3.46	-5.4	5.7e-08	-0.03	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CRIPAK	0.31	0.15	enet	34	0.26	1.2e-31	-3.10	-5.3	9.9e-08	0.04	1.00	0.00	FALSE
11	GTEx	Ovary	CRIPAK	0.43	0.27	enet	19	0.32	9.0e-09	-4.12	-5.3	1.0e-07	0.03	0.46	0.06	FALSE
9	GTEx	Muscle Skeletal	CRIPAK	0.25	0.11	enet	32	0.18	7.6e-18	-4.12	-5.3	1.1e-07	0.03	1.00	0.00	FALSE
12	GTEx	Whole Blood	CRIPAK	0.38	0.17	lasso	9	0.28	3.4e-26	-3.46	-5.2	1.5e-07	0.02	1.00	0.00	FALSE
4	GTEx	Brain Putamen basal ganglia	CRIPAK	0.30	0.00	enet	25	0.10	1.9e-03	-3.03	-5.1	2.9e-07	0.11	0.06	0.10	FALSE