TWAS
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Traits
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Traits
:
Leg fat-free mass (left)
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chr4:110,042,428-111,439,602
Best TWAS P=5.75e-08 · Best GWAS P=3.86e-08 conditioned to 1
110M
110.2M
110.4M
110.6M
110.8M
111M
111.2M
111.4M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
GAR1
0.04
0.06
lasso
2
0.06
8.1e-07
5.5
5.4
5.7e-08
0.99
0.00
1.00
TRUE
4
The Cancer Genome Atlas
Pheochromocytoma and Paraganglioma
GAR1
0.10
0.09
lasso
2
0.07
6.8e-04
5.5
-5.4
7.2e-08
-0.99
0.00
0.95
FALSE
1
GTEx
Brain Frontal Cortex BA9
GAR1
0.22
0.08
lasso
3
0.04
2.9e-02
5.2
-5.4
8.6e-08
-0.94
0.01
0.84
FALSE
2
ROSMAP
Brain Pre-frontal Cortex
GAR1
0.18
0.24
enet
17
0.24
2.2e-30
5.5
-5.2
1.5e-07
-0.98
0.00
1.00
FALSE