[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr5:125,679,739-128,220,643

Best TWAS P=5.83e-41 · Best GWAS P=6.64e-40 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	FLJ33630	0.06	0.07	lasso	6	0.07	8.6e-09	-3.17	-6.4	1.2e-10	-0.52	0.62	0.38	FALSE
2	GTEx	Adipose Subcutaneous	CTC-228N24.3	0.24	0.15	enet	16	0.20	3.4e-16	13.20	-12.5	8.0e-36	-0.97	0.00	1.00	FALSE
3	GTEx	Adipose Visceral Omentum	CTC-228N24.3	0.24	0.16	enet	19	0.16	1.8e-08	13.20	-11.5	1.5e-30	-0.80	0.00	1.00	FALSE
4	GTEx	Adrenal Gland	CTC-228N24.3	0.34	0.10	lasso	9	0.09	4.2e-04	9.96	-11.2	4.6e-29	-0.88	0.03	0.96	FALSE
5	GTEx	Artery Aorta	CTC-228N24.3	0.20	0.04	lasso	8	0.07	7.4e-05	5.67	-11.9	7.8e-33	-0.91	0.11	0.86	FALSE
6	GTEx	Artery Coronary	CTC-228N24.3	0.31	0.10	lasso	3	0.10	2.9e-04	12.60	-12.6	3.3e-36	-0.86	0.01	0.90	FALSE
7	GTEx	Artery Tibial	CTC-228N24.3	0.20	0.16	lasso	7	0.14	3.0e-11	13.20	-13.4	5.8e-41	-0.99	0.00	1.00	TRUE
8	GTEx	Brain Caudate basal ganglia	PRRC1	0.39	0.00	enet	5	0.06	7.1e-03	5.30	-5.2	2.5e-07	-0.19	0.07	0.05	FALSE
9	GTEx	Brain Cerebellar Hemisphere	SLC12A2	0.45	-0.01	enet	20	0.01	2.1e-01	9.82	-7.6	2.7e-14	-0.46	0.04	0.33	FALSE
10	GTEx	Brain Cerebellar Hemisphere	CTC-228N24.3	0.25	0.00	lasso	6	0.05	2.2e-02	0.29	-6.0	2.1e-09	-0.49	0.03	0.62	FALSE
11	GTEx	Brain Cerebellum	C5orf63	0.20	0.07	lasso	3	0.05	1.7e-02	4.75	-5.4	7.3e-08	0.04	0.05	0.80	TRUE
12	GTEx	Brain Cerebellum	CTC-228N24.3	0.31	0.04	lasso	5	0.12	2.9e-04	13.20	-11.0	3.4e-28	-0.84	0.01	0.97	FALSE
13	GTEx	Cells EBV-transformed lymphocytes	CTC-228N24.3	0.24	-0.01	enet	26	0.04	2.2e-02	8.41	-8.5	1.7e-17	-0.57	0.03	0.70	FALSE
14	GTEx	Cells Transformed fibroblasts	CTC-228N24.3	0.24	0.16	enet	26	0.16	8.6e-12	13.20	-12.5	1.1e-35	-0.89	0.00	1.00	FALSE
15	GTEx	Colon Sigmoid	CTC-228N24.3	0.20	0.22	enet	11	0.23	1.1e-08	12.60	-12.4	3.5e-35	-0.92	0.01	0.99	FALSE
16	GTEx	Esophagus Gastroesophageal Junction	CTC-228N24.3	0.20	0.04	enet	22	0.13	2.1e-05	-3.18	-7.0	1.8e-12	-0.51	0.05	0.68	FALSE
17	GTEx	Esophagus Mucosa	CTC-228N24.3	0.18	0.14	enet	11	0.14	9.8e-10	13.20	-13.0	1.8e-38	-0.93	0.00	1.00	FALSE
18	GTEx	Esophagus Muscularis	CTC-228N24.3	0.24	0.08	enet	29	0.14	1.4e-08	12.60	-9.9	4.6e-23	-0.75	0.01	0.99	FALSE
19	GTEx	Heart Atrial Appendage	CTC-228N24.3	0.22	0.07	lasso	5	0.07	4.1e-04	12.50	-10.7	8.5e-27	-0.87	0.00	0.99	FALSE
20	GTEx	Heart Left Ventricle	CTC-228N24.3	0.24	0.15	lasso	7	0.19	1.9e-10	11.90	-10.8	3.1e-27	-0.84	0.01	0.99	FALSE
21	GTEx	Lung	CTC-228N24.3	0.18	0.14	enet	16	0.14	3.2e-11	13.20	-11.7	9.9e-32	-0.95	0.00	1.00	FALSE
22	GTEx	Muscle Skeletal	CTC-228N24.3	0.25	0.20	lasso	5	0.21	1.6e-20	13.20	-12.2	4.6e-34	-0.95	0.00	1.00	FALSE
23	GTEx	Nerve Tibial	CTC-228N24.3	0.32	0.18	lasso	10	0.16	1.6e-11	12.60	-12.7	7.1e-37	-0.96	0.01	0.99	FALSE
24	GTEx	Pancreas	CTC-228N24.3	0.14	0.19	lasso	2	0.17	1.1e-07	13.20	-13.2	6.7e-40	-1.00	0.00	1.00	FALSE
25	GTEx	Skin Not Sun Exposed Suprapubic	CTC-228N24.3	0.29	0.21	lasso	7	0.22	1.7e-12	13.20	-13.1	3.4e-39	-0.97	0.00	1.00	FALSE
26	GTEx	Skin Sun Exposed Lower leg	CTC-228N24.3	0.29	0.17	enet	12	0.22	4.3e-18	12.50	-12.5	4.7e-36	-0.90	0.00	1.00	FALSE
27	GTEx	Spleen	CTC-228N24.3	0.26	0.03	enet	15	0.05	1.8e-02	5.67	-10.3	1.1e-24	-0.66	0.04	0.56	FALSE
28	GTEx	Stomach	SLC12A2	0.23	0.17	enet	19	0.17	1.6e-08	7.99	-8.4	3.8e-17	-0.45	0.80	0.16	FALSE
29	GTEx	Stomach	CTC-228N24.3	0.17	0.04	lasso	6	0.08	1.5e-04	11.90	-12.0	2.7e-33	-0.81	0.02	0.95	FALSE
30	GTEx	Testis	CTC-228N24.3	0.30	0.16	lasso	6	0.14	1.1e-06	13.20	-11.8	3.4e-32	-0.93	0.00	1.00	FALSE
31	GTEx	Thyroid	CTC-228N24.3	0.31	0.15	enet	32	0.18	4.6e-14	13.20	-10.6	5.1e-26	-0.78	0.00	1.00	FALSE
32	METSIM	Adipose	CTC-228N24.3	0.17	0.19	lasso	6	0.18	1.9e-26	13.20	-13.1	1.8e-39	-1.00	0.00	1.00	FALSE
33	ROSMAP	Brain Pre-frontal Cortex	CTC-228N24.3	0.15	0.09	lasso	3	0.12	8.0e-15	13.20	-11.4	6.2e-30	-0.88	0.00	1.00	FALSE
34	The Cancer Genome Atlas	Breast Invasive Carcinoma	FLJ33630	0.05	0.04	enet	14	0.03	2.1e-07	13.20	-12.4	4.8e-35	-0.88	0.00	1.00	FALSE
35	The Cancer Genome Atlas	Glioblastoma Multiforme	FLJ33630	0.38	0.20	lasso	5	0.17	6.5e-06	13.20	-13.1	1.7e-39	-0.99	0.00	1.00	FALSE
36	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FLJ33630	0.10	0.07	lasso	3	0.08	7.0e-09	12.60	-12.4	1.6e-35	-0.95	0.00	1.00	FALSE
37	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	FLJ33630	0.10	0.06	enet	18	0.08	2.0e-09	13.20	-10.1	7.2e-24	-0.79	0.00	1.00	FALSE
38	The Cancer Genome Atlas	Brain Lower Grade Glioma	FBN2	0.12	0.02	enet	17	0.05	1.7e-06	9.00	-7.0	1.8e-12	-0.53	0.04	0.93	FALSE
39	The Cancer Genome Atlas	Brain Lower Grade Glioma	FLJ33630	0.19	0.16	enet	4	0.16	1.2e-17	13.20	-13.1	2.7e-39	-1.00	0.00	1.00	FALSE
40	The Cancer Genome Atlas	Lung Adenocarcinoma	FLJ33630	0.07	0.05	lasso	1	0.04	1.3e-05	12.60	-12.6	3.9e-36	-0.96	0.01	0.99	FALSE
41	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	FLJ33630	0.09	0.08	lasso	4	0.09	4.9e-10	13.20	-13.2	1.3e-39	-1.00	0.00	1.00	FALSE
42	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	FLJ33630	0.08	0.03	lasso	2	0.04	5.7e-03	12.60	-12.8	2.4e-37	-0.90	0.01	0.89	FALSE
43	The Cancer Genome Atlas	Prostate Adenocarcinoma	FLJ33630	0.08	0.05	blup	70	0.04	4.4e-05	12.60	-12.5	4.7e-36	-0.86	0.00	1.00	FALSE
44	The Cancer Genome Atlas	Prostate Adenocarcinoma	SLC12A2	0.04	0.02	enet	17	0.02	3.3e-03	12.60	7.7	1.6e-14	0.69	0.01	0.86	FALSE
45	The Cancer Genome Atlas	Stomach Adenocarcinoma	FLJ33630	0.07	0.02	blup	70	0.02	1.5e-02	7.59	-8.9	8.2e-19	-0.48	0.12	0.14	FALSE
46	The Cancer Genome Atlas	Testicular Germ Cell Tumors	FLJ33630	0.26	0.14	lasso	3	0.13	2.2e-05	13.20	-13.3	4.4e-40	-0.99	0.00	1.00	FALSE
47	The Cancer Genome Atlas	Thyroid Carcinoma	FLJ33630	0.10	0.10	lasso	2	0.09	5.3e-09	13.20	-13.2	1.3e-39	-1.00	0.00	1.00	FALSE