TWAS hub - C5orf63

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1230	0.0330	4.2e-14	0.116	0.121	0.151	0.129	0.148	5.8e-14	1.8e-14	5.9e-18	1.9e-15	1.4e-17
2	GTEx	Adipose Subcutaneous	0.0990	0.0300	3.3e-08	0.121	NA	0.117	NA	0.117	4.5e-10	NA	8.7e-10	NA	9.2e-10
3	GTEx	Adipose Visceral Omentum	0.1070	0.0450	1.5e-03	0.068	NA	0.013	NA	0.053	2.1e-04	NA	6.6e-02	NA	9.8e-04
4	GTEx	Adrenal Gland	0.2169	0.0759	1.8e-05	0.052	NA	0.107	NA	0.123	6.0e-03	NA	1.1e-04	NA	3.7e-05
5	GTEx	Artery Aorta	0.1940	0.0500	1.2e-12	0.274	NA	0.274	NA	0.071	2.0e-15	NA	2.1e-15	NA	9.4e-05
6	GTEx	Artery Coronary	0.2020	0.0730	2.8e-05	0.137	NA	0.030	NA	0.153	2.4e-05	NA	3.3e-02	NA	7.9e-06
7	GTEx	Artery Tibial	0.2071	0.0426	6.1e-16	0.193	NA	0.221	NA	0.232	4.5e-15	NA	3.1e-17	NA	3.9e-18
8	GTEx	Brain Cerebellar Hemisphere	0.2080	0.0970	3.1e-03	0.050	NA	0.030	NA	0.046	2.1e-02	NA	5.7e-02	NA	2.5e-02
9	GTEx	Brain Cerebellum	0.2040	0.0770	2.4e-04	0.067	NA	0.035	NA	0.046	5.0e-03	NA	3.3e-02	NA	1.7e-02
10	GTEx	Brain Frontal Cortex BA9	0.1089	0.0538	5.5e-03	0.003	NA	-0.001	NA	-0.010	2.6e-01	NA	3.5e-01	NA	7.3e-01
11	GTEx	Cells Transformed fibroblasts	0.1710	0.0500	4.6e-11	0.139	NA	0.142	NA	0.149	1.3e-10	NA	8.9e-11	NA	2.7e-11
12	GTEx	Colon Sigmoid	0.1670	0.0510	6.0e-07	0.230	NA	0.234	NA	0.229	1.2e-08	NA	8.5e-09	NA	1.3e-08
13	GTEx	Esophagus Gastroesophageal Junction	0.2100	0.0660	5.3e-07	0.150	NA	0.145	NA	0.165	4.5e-06	NA	6.7e-06	NA	1.4e-06
14	GTEx	Esophagus Muscularis	0.1570	0.0460	1.3e-09	0.183	NA	0.172	NA	0.185	2.7e-11	NA	1.2e-10	NA	2.1e-11
15	GTEx	Heart Atrial Appendage	0.1130	0.0490	6.1e-04	-0.002	NA	-0.004	NA	-0.006	4.0e-01	NA	5.5e-01	NA	7.2e-01
16	GTEx	Nerve Tibial	0.2113	0.0450	1.7e-16	0.317	NA	0.307	NA	0.315	6.3e-23	NA	3.5e-22	NA	8.9e-23
17	GTEx	Skin Not Sun Exposed Suprapubic	0.1370	0.0550	7.5e-04	0.015	NA	0.008	NA	0.011	4.9e-02	NA	1.1e-01	NA	7.4e-02
18	GTEx	Skin Sun Exposed Lower leg	0.0460	0.0210	2.7e-03	0.058	NA	0.033	NA	0.033	1.3e-05	NA	9.7e-04	NA	8.8e-04
19	GTEx	Spleen	0.3440	0.1080	3.8e-04	-0.008	NA	-0.012	NA	0.000	5.8e-01	NA	9.2e-01	NA	3.1e-01
20	GTEx	Uterus	0.2650	0.1230	5.9e-03	0.118	NA	-0.007	NA	-0.005	2.2e-03	NA	4.7e-01	NA	4.1e-01
21	GTEx	Vagina	0.2760	0.1150	7.5e-03	0.054	NA	-0.008	NA	-0.013	2.3e-02	NA	5.4e-01	NA	8.8e-01
22	ROSMAP	Brain Pre-frontal Cortex	0.0928	0.0243	8.0e-14	0.132	0.125	0.122	0.128	0.125	1.3e-16	8.5e-16	2.1e-15	4.5e-16	9.9e-16

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	22
Lung FEV1/FVC ratio	9.4	47.6	63.2	6.9	7.9	7.6	7.0	7.6	-7.7	7.1	6.4	3.8	6.2	7.9	7.9	7.6	8.0	6.2	7.8	7.0	6.8	5.8	6.8	7.2
Wheeze or whistling in the chest in last year	8.4	15.0	20.0	-4.2	-4.3	-4.0	-3.5	-3.9	3.9	-4.4	-3.9	-2.5	-2.4	-4.0	-4.4	-4.4	-4.2	-4.1	-4.3	-4.1	-4.4	-2.8	-4.5	-4.2
Deep venous thrombosis (DVT) (self-reported)	7.2	9.2	15.3	-2.8	-3.2	-3.2	-3.8	-3.1	3.2	-2.8	-2.8	-2.8	-3.5	-3.1	-3.3	-3.1	-3.2	-3.3	-3.2	-2.7	-2.6	-3.9	-2.8	-2.7
Smoking status: Previous	6.6	9.8	13.0	-2.9	-3.3	-3.4	-2.6	-3.5	3.3	-2.7	-3.5	-3.6	-3.1	-3.3	-3.4	-3.6	-3.3	-3.4	-3.4	-2.2	-2.9	-3.4	-3.4	-2.7
Blood clot in the leg (DVT)	5.6	7.2	12.2	-2.4	-2.9	-2.8	-3.4	-2.7	2.9	-2.3	-2.5	-2.5	-3.0	-2.8	-2.9	-2.7	-2.8	-3.1	-2.9	-2.2	-2.2	-3.5	-2.4	-2.4
Ulcerative Colitis (UC)	5.4	10.2	13.8	-3.5	-3.5	-3.4	-2.8	-3.2	3.4	-3.5	-2.2	-1.7	-3.5	-3.5	-3.5	-3.3	-3.4	-3.4	-3.4	-3.5	-3.3	-2.8	-3.5	-3.7
Asthma	5.4	10.6	21.2	-3.9	-3.5	-3.4	-2.9	-3.2	3.1	-4.1	-3.0	-1.0	-2.3	-3.4	-3.6	-3.3	-3.6	-2.6	-3.7	-4.6	-3.6	-1.7	-3.0	-4.1
Schizophrenia (2018)	5.1	10.5	13.6	3.4	3.7	3.6	2.7	3.4	-3.5	3.5	3.0	2.5	2.6	3.6	3.5	3.4	3.5	3.3	3.6	3.4	3.3	2.6	3.5	3.3
Suffer from ‘nerves’	4.9	7.7	12.6	3.0	3.1	2.8	2.0	3.0	-3.0	3.0	3.2	1.4	2.4	3.1	3.0	3.0	2.9	2.6	3.0	3.0	2.9	1.4	3.0	3.5
Asthma (self-reported)	4.9	9.8	20.1	-3.8	-3.4	-3.3	-2.9	-3.0	2.9	-4.0	-2.8	-0.9	-2.2	-3.2	-3.5	-3.1	-3.4	-2.5	-3.6	-4.5	-3.5	-1.8	-2.9	-4.1
Past tobacco smoking	4.8	8.8	16.0	2.7	3.1	3.1	2.4	3.3	-3.2	2.5	3.3	4.0	3.1	3.1	3.1	3.4	3.0	3.4	3.0	1.9	2.7	3.4	3.2	2.3
Emphysema/chronic bronchitis	4.8	5.4	8.6	-1.9	-2.7	-2.4	-2.3	-2.4	2.7	-2.2	-2.0	-1.8	-1.7	-2.7	-2.7	-2.9	-2.7	-2.1	-2.5	-1.8	-2.5	-2.6	-2.8	-2.0
Illnesses of father: Heart disease	4.7	6.5	10.0	2.7	2.9	2.5	2.5	2.7	-2.8	2.9	2.2	1.2	2.1	3.0	2.5	2.8	2.5	2.2	2.5	2.8	3.0	2.2	2.7	3.2
Schizophrenia (2014)	4.6	10.1	13.4	3.4	3.7	3.6	2.9	3.4	-3.4	3.4	2.8	2.0	2.6	3.5	3.5	3.4	3.6	3.3	3.6	3.3	3.2	2.6	3.2	3.3
Respiratory disease	4.6	10.3	19.9	-3.7	-3.5	-3.2	-2.8	-3.0	3.2	-4.0	-3.0	-1.0	-2.2	-3.4	-3.5	-3.4	-3.5	-3.0	-3.5	-4.1	-3.7	-1.6	-3.2	-4.5
Forced vital capacity (FVC), Best measure	4.6	16.8	22.9	-4.5	-4.6	-4.2	-2.9	-4.6	4.2	-4.4	-4.3	-3.2	-4.1	-4.5	-4.6	-4.1	-4.6	-4.3	-4.8	-4.7	-3.9	-2.3	-3.8	-4.6
Irritable Bowel Disease (IBD)	4.0	9.6	14.4	-3.6	-3.3	-3.6	-2.7	-3.4	3.2	-3.6	-2.4	-1.3	-3.3	-3.2	-3.5	-3.2	-3.4	-2.4	-3.5	-3.8	-3.2	-2.5	-3.1	-3.3
Forced expiratory volume in 1-second (FEV1), predicted	4.0	8.4	13.4	-3.3	-3.1	-2.9	-2.4	-3.1	2.6	-3.3	-3.0	-2.3	-3.0	-2.9	-3.4	-2.8	-3.4	-2.5	-3.5	-3.7	-2.7	-1.8	-2.5	-3.5
Forced vital capacity (FVC)	3.8	14.7	23.9	-4.6	-4.2	-4.1	-2.1	-4.5	3.7	-4.4	-4.0	-2.7	-3.7	-4.1	-4.4	-3.7	-4.2	-3.8	-4.6	-4.9	-3.7	-1.7	-3.3	-4.4
Leg predicted mass (right)	3.8	20.2	31.9	-5.1	-4.6	-4.8	-3.6	-4.5	4.6	-4.8	-4.5	-5.7	-4.5	-4.6	-4.7	-4.6	-4.7	-4.8	-4.6	-4.9	-4.4	-4.1	-4.2	-4.1
Intelligence (Savage-Jansen 2018)	3.7	11.4	17.3	-3.0	-3.8	-3.5	-3.4	-3.5	3.9	-3.2	-4.2	-2.8	-3.5	-3.8	-3.7	-3.6	-3.9	-2.6	-3.7	-3.1	-3.2	-2.8	-3.8	-3.0
Chronic bronchitis/emphysema (father)	3.7	4.3	7.9	-2.0	-2.3	-2.6	-1.4	-2.5	2.1	-1.9	-2.8	-2.2	-2.0	-2.3	-2.5	-2.2	-2.5	-1.6	-2.6	-1.9	-1.6	-1.3	-1.8	-1.6
Leg fat-free mass (right)	3.7	19.8	31.6	-5.0	-4.5	-4.7	-3.6	-4.5	4.5	-4.7	-4.5	-5.6	-4.5	-4.5	-4.6	-4.5	-4.7	-4.8	-4.5	-4.9	-4.3	-4.0	-4.2	-4.0
Medication: Ventolin 100micrograms inhaler	3.6	4.7	7.6	-2.4	-2.4	-2.3	-1.9	-2.4	2.0	-2.7	-2.6	-0.5	-1.5	-2.2	-2.3	-2.3	-2.3	-1.3	-2.5	-2.8	-2.6	-0.8	-2.4	-2.4
Chest pain or discomfort	3.6	5.2	8.9	-2.5	-2.3	-2.4	-2.9	-2.3	2.2	-2.4	-1.2	-1.8	-1.6	-2.2	-2.5	-2.4	-2.5	-2.6	-2.5	-2.2	-2.3	-3.0	-2.2	-2.4
Medication: Co-codamol	3.5	4.0	6.9	-2.0	-2.3	-2.6	-2.1	-2.4	2.1	-2.0	-2.0	-1.1	-1.4	-2.4	-2.4	-2.3	-2.5	-1.6	-2.4	-2.0	-1.8	-1.7	-1.8	-1.5
Bipolar Disorder or Schizophrenia	3.4	8.3	11.3	2.9	3.4	3.3	2.3	3.0	-3.4	3.0	3.0	2.1	2.0	3.3	3.1	3.1	3.2	3.3	3.2	2.9	2.9	2.3	3.0	2.9
Rheumatoid Arthritis	3.4	4.7	7.6	-2.7	-2.2	-2.0	-1.7	-1.7	2.2	-2.5	-2.3	-2.0	-2.3	-2.2	-2.0	-2.1	-1.9	-2.8	-1.9	-2.7	-2.3	-2.0	-2.4	-2.5
Allergy	3.4	7.9	10.6	2.7	3.0	2.7	3.2	2.9	-3.0	2.9	3.2	2.4	2.9	2.9	3.3	3.0	3.2	2.4	3.1	3.0	2.6	2.6	2.6	2.5
Ever had stillbirth, spontaneous miscarriage or termination	3.3	3.6	5.7	-2.1	-2.2	-2.3	-1.2	-2.1	2.1	-2.2	-2.0	-1.3	-1.2	-2.0	-2.2	-2.0	-2.1	-1.2	-2.3	-2.4	-1.9	-1.0	-1.7	-2.2
Ever smoked	3.3	5.9	12.2	-2.2	-2.4	-2.8	-2.0	-2.8	2.5	-1.9	-2.7	-3.5	-2.6	-2.5	-2.6	-2.7	-2.6	-2.8	-2.5	-1.6	-1.9	-2.7	-2.4	-1.6
Leg fat-free mass (left)	3.2	17.1	28.9	-4.7	-4.2	-4.3	-3.4	-4.0	4.2	-4.3	-4.1	-5.4	-4.2	-4.2	-4.2	-4.2	-4.3	-4.6	-4.2	-4.4	-4.0	-4.0	-4.0	-3.8
Leg predicted mass (left)	3.2	17.2	28.6	-4.7	-4.2	-4.4	-3.5	-4.0	4.2	-4.3	-4.0	-5.3	-4.2	-4.2	-4.2	-4.2	-4.3	-4.6	-4.2	-4.4	-4.0	-4.0	-4.0	-3.8
Impedance of leg (right)	3.1	15.0	39.6	3.9	3.8	4.1	3.5	4.2	-4.0	3.5	3.4	6.3	4.3	3.8	4.0	3.9	4.2	4.2	3.9	3.6	3.1	4.7	2.9	2.4
Verbal and Numeric Reasoning (VNR)	2.9	7.0	11.5	-2.4	-3.0	-2.4	-2.7	-2.8	3.0	-2.8	-3.4	-2.1	-2.3	-2.8	-3.0	-2.9	-3.1	-2.1	-3.0	-2.6	-2.7	-1.8	-2.8	-2.7
Ulcerative Colitis	2.7	4.0	8.3	-2.1	-2.1	-1.5	-1.8	-1.6	2.2	-1.9	-1.6	-2.4	-1.9	-2.1	-1.9	-2.1	-1.9	-2.9	-1.8	-1.7	-2.1	-2.0	-2.5	-2.2
Other serious medical condition/disability diagnosed by doctor	2.7	3.5	5.4	-2.1	-2.0	-2.0	-2.1	-1.9	1.9	-2.2	-1.2	-0.9	-1.0	-1.9	-2.0	-2.0	-2.1	-1.5	-2.0	-2.3	-2.0	-2.3	-1.8	-1.8
Impedance of leg (left)	2.7	13.3	39.3	3.7	3.5	3.9	3.5	3.8	-3.7	3.1	2.9	6.3	4.2	3.5	3.6	3.6	3.8	4.3	3.5	3.1	2.9	4.7	2.7	2.2
Mouth/teeth dental problems: Loose teeth	2.7	3.2	6.0	1.5	1.9	1.9	2.3	2.0	-1.8	1.5	2.5	1.8	1.7	1.9	2.0	1.8	2.1	1.6	2.0	1.5	1.3	2.0	1.5	1.4
Arm fat-free mass (right)	2.6	13.1	20.1	-4.4	-3.6	-3.6	-2.4	-3.3	3.5	-4.0	-3.8	-4.5	-3.9	-3.6	-3.5	-3.5	-3.4	-4.4	-3.5	-4.2	-3.9	-2.9	-3.8	-3.8
Qualifications: nursing, teaching	2.6	4.0	6.2	-1.9	-2.4	-2.3	-1.7	-2.3	2.1	-1.8	-2.2	-1.1	-1.3	-2.4	-2.5	-2.2	-2.5	-2.3	-2.5	-1.8	-1.6	-1.1	-2.0	-2.1
Pain experienced in last month	2.6	4.4	7.5	2.6	2.2	2.7	1.8	2.4	-2.0	2.3	1.5	1.4	1.1	2.2	2.6	2.2	2.6	2.1	2.5	2.6	1.8	1.9	1.6	1.8
Shortness of breath walking on level ground	2.5	3.0	5.0	-1.4	-1.8	-2.2	-2.0	-2.2	1.9	-1.2	-1.8	-2.2	-0.9	-1.9	-2.1	-2.0	-2.2	-1.5	-2.0	-1.2	-1.1	-2.0	-1.2	-0.8
Heart disease (siblings)	2.5	3.0	5.6	1.9	1.9	2.1	1.5	2.2	-1.7	2.1	1.6	1.0	1.4	1.8	2.1	1.8	2.1	0.6	2.1	2.4	1.6	0.8	1.4	1.9
Financial difficulties in last 2 years	2.4	3.3	5.9	-1.7	-2.3	-1.6	-0.9	-1.8	2.4	-2.0	-1.8	-1.9	-1.7	-2.3	-1.9	-2.0	-1.9	-1.3	-1.9	-2.1	-2.0	-1.0	-1.7	-2.0
Commuting to job workplace: Walk	2.4	2.6	4.7	-1.8	-1.5	-1.0	-2.1	-1.2	1.9	-2.0	-1.5	-1.4	-1.8	-1.6	-1.1	-1.4	-1.1	-1.5	-1.1	-2.0	-2.1	-1.7	-1.9	-2.2
Exposure to tobacco smoke at home	2.3	2.6	4.4	-1.9	-1.7	-2.1	-1.5	-1.7	1.4	-1.8	-1.1	-1.3	-0.9	-1.6	-1.9	-1.7	-1.9	-1.8	-1.9	-1.8	-1.5	-1.7	-1.5	-1.7
Mean time to correctly identify matches	2.3	4.3	7.4	2.1	2.4	2.5	1.9	2.5	-2.0	2.2	1.8	0.6	0.8	2.4	2.7	2.4	2.7	1.8	2.6	2.1	2.0	1.3	2.0	2.3
Arm predicted mass (right)	2.3	12.0	17.9	-4.2	-3.4	-3.4	-2.2	-3.1	3.4	-3.9	-3.6	-4.2	-3.6	-3.4	-3.3	-3.4	-3.3	-4.2	-3.4	-4.0	-3.7	-2.6	-3.7	-3.6
Whole body fat-free mass	2.3	12.9	21.6	-4.3	-3.6	-3.8	-2.5	-3.5	3.5	-3.9	-3.7	-4.7	-3.5	-3.6	-3.6	-3.5	-3.7	-4.2	-3.6	-4.1	-3.5	-3.0	-3.5	-3.6
Whole body water mass	2.3	13.2	21.6	-4.3	-3.6	-3.8	-2.6	-3.5	3.6	-3.9	-3.7	-4.7	-3.5	-3.6	-3.7	-3.6	-3.7	-4.2	-3.7	-4.1	-3.6	-3.1	-3.5	-3.6
Basal metabolic rate	2.3	12.6	22.3	-4.2	-3.5	-3.7	-2.7	-3.3	3.5	-3.8	-3.7	-4.7	-3.6	-3.5	-3.6	-3.5	-3.6	-4.1	-3.6	-4.0	-3.5	-3.1	-3.4	-3.5
Body Mass Index (BMI) (2010)	2.2	3.0	5.9	1.6	2.1	1.5	1.5	1.4	-2.1	2.1	2.2	0.1	0.8	2.1	1.8	2.0	1.8	1.0	1.7	1.9	2.2	0.5	2.3	2.4
Type 2 Diabetes (T2D) (2012)	2.1	2.4	4.2	1.5	1.6	1.4	2.0	1.3	-1.5	1.8	1.8	0.7	1.4	1.7	1.5	1.7	1.5	1.0	1.4	1.6	1.8	1.3	2.0	1.7
Loud music exposure frequency	2.1	2.3	5.2	-1.5	-1.6	-2.1	-1.0	-2.3	1.3	-1.3	-1.8	-1.7	-1.4	-1.5	-1.9	-1.5	-1.9	-1.4	-2.0	-1.5	-0.9	-1.3	-0.9	-1.0
Alcohol drinker status: Previous	2.1	2.4	4.4	0.5	1.9	1.7	1.6	1.9	-2.1	0.7	2.0	1.4	2.1	1.9	1.9	1.9	1.9	1.3	1.8	0.3	0.9	1.2	1.7	0.8
Schizophrenia vs Biploar Disorder	2.0	2.6	7.9	1.7	1.6	1.2	1.8	1.3	-1.6	1.4	1.4	2.4	2.8	1.4	1.5	1.2	1.3	1.9	1.5	1.6	1.2	1.5	1.4	2.1
Systolic Blood Pressure	2.0	10.0	15.7	3.3	3.8	3.2	1.4	3.3	-4.0	3.3	3.1	2.8	2.1	3.9	3.4	3.8	3.3	3.3	3.2	3.0	3.5	2.1	3.9	3.2
Frequency of tiredness / lethargy in last 2 weeks	2.0	3.2	5.2	-1.6	-2.3	-1.9	-0.7	-2.2	2.1	-1.8	-1.5	-1.6	-1.8	-2.1	-2.2	-2.0	-2.1	-1.7	-2.2	-1.8	-1.6	-1.0	-1.8	-1.7
Ever depressed for a whole week	2.0	2.5	7.3	0.7	1.5	1.3	1.8	1.5	-1.6	0.7	2.3	2.7	2.0	1.5	1.5	1.5	1.6	2.6	1.4	0.4	0.9	1.9	1.6	0.9
Crohns Disease (2017)	1.9	4.2	8.1	-2.4	-2.2	-2.6	-1.6	-2.5	2.0	-2.5	-1.8	-0.0	-2.0	-2.0	-2.5	-2.0	-2.5	-0.5	-2.7	-2.9	-1.9	-1.5	-1.7	-1.9
Reaction Time	1.9	3.6	6.1	2.3	2.1	2.1	1.4	2.0	-1.8	2.4	1.9	0.1	0.4	2.1	2.1	2.2	2.1	1.1	2.0	2.3	2.5	0.9	2.3	2.3
Fluid intelligence score	1.8	3.7	6.8	-2.1	-1.8	-1.6	-2.0	-1.6	1.9	-2.2	-2.6	-2.0	-2.0	-1.8	-1.7	-1.8	-1.8	-1.7	-1.8	-2.3	-2.2	-1.9	-1.9	-2.1
Arm fat-free mass (left)	1.8	8.9	16.0	-3.6	-2.9	-2.9	-1.9	-2.6	2.9	-3.3	-3.2	-4.0	-3.1	-2.8	-2.9	-2.8	-2.9	-3.6	-2.9	-3.5	-3.1	-2.4	-3.0	-3.0
Had menopause	1.7	2.2	5.0	0.8	1.9	1.8	1.2	2.1	-1.6	0.9	1.2	1.6	1.2	1.8	2.2	1.5	2.2	1.3	2.2	1.0	0.5	1.2	0.9	0.9
Pain all over the body in last month	1.7	1.8	4.7	-0.7	-1.8	-1.8	-1.5	-2.2	1.7	-1.0	-0.4	0.1	0.0	-1.8	-1.8	-1.6	-2.0	-0.6	-1.8	-1.0	-0.8	-1.5	-0.9	-0.7
Illnesses of siblings	1.7	2.4	4.7	-1.4	-1.8	-1.9	-1.6	-2.2	1.6	-1.4	-0.5	-1.2	-1.0	-1.7	-2.2	-1.6	-2.1	-1.2	-2.1	-1.7	-1.0	-1.8	-1.1	-1.2
Weight	1.7	8.4	17.8	-3.2	-2.8	-2.7	-2.8	-2.4	2.8	-3.0	-3.0	-4.2	-3.2	-2.7	-2.8	-2.9	-2.8	-3.1	-2.7	-3.0	-3.0	-2.9	-3.0	-2.6
Trunk fat-free mass	1.7	9.6	16.2	-3.8	-3.1	-3.3	-1.9	-3.0	3.0	-3.3	-3.4	-4.0	-2.9	-3.0	-3.1	-2.9	-3.1	-3.8	-3.2	-3.6	-3.0	-2.3	-3.0	-3.4
Headache pain in last month	1.7	2.9	5.6	-1.9	-2.0	-2.2	-1.2	-2.3	1.6	-1.8	-1.2	-0.5	-0.8	-1.9	-2.3	-1.8	-2.3	-1.6	-2.4	-2.1	-1.4	-1.1	-1.4	-1.3
Arm predicted mass (left)	1.7	8.6	16.2	-3.6	-2.8	-2.8	-2.0	-2.5	2.8	-3.2	-3.2	-4.0	-3.1	-2.8	-2.8	-2.8	-2.8	-3.5	-2.8	-3.4	-3.0	-2.4	-3.0	-3.1
Systolic blood pressure, automated reading	1.6	4.5	7.9	2.0	2.7	2.6	0.8	2.8	-2.5	2.1	2.3	1.2	1.3	2.6	2.7	2.5	2.7	1.7	2.7	2.0	1.9	0.6	2.3	1.7
Number of live births	1.6	2.2	4.8	1.3	1.4	1.9	2.2	1.6	-1.0	1.3	1.1	1.1	1.5	1.3	1.9	1.6	2.0	1.5	1.9	1.3	1.0	1.9	1.1	1.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.6	5.1	7.2	-2.5	-2.4	-2.1	-1.0	-2.5	2.2	-2.4	-2.6	-2.4	-2.5	-2.4	-2.5	-2.1	-2.5	-2.6	-2.7	-2.7	-2.0	-0.9	-2.0	-2.7
Trunk predicted mass	1.6	9.4	15.9	-3.8	-3.0	-3.2	-1.9	-2.9	3.0	-3.3	-3.3	-4.0	-2.9	-3.0	-3.0	-2.9	-3.1	-3.8	-3.1	-3.5	-3.0	-2.2	-3.0	-3.4
Medication: Omeprazole	1.6	1.9	6.0	-1.9	-1.1	-1.4	-1.5	-1.2	1.2	-1.4	-1.3	-1.3	-1.4	-1.2	-1.0	-1.1	-1.0	-2.0	-0.9	-1.6	-1.3	-2.4	-1.0	-1.5
Average weekly champagne plus white wine intake	1.6	2.2	4.0	-1.3	-1.8	-1.6	-1.4	-1.7	1.6	-1.4	-0.8	-0.1	-1.1	-1.6	-1.9	-1.6	-1.9	-1.6	-2.0	-1.3	-1.3	-1.2	-1.5	-1.8
Fractured/broken bones in last 5 years	1.6	2.0	4.3	-1.9	-1.4	-1.5	-1.2	-1.3	1.2	-1.7	-1.6	0.2	-1.1	-1.5	-1.3	-1.4	-1.2	-1.6	-1.4	-1.7	-1.7	-0.7	-1.6	-2.1
Medication: Omeprazole (e.g. Zanprol)	1.6	1.9	4.4	-1.9	-1.3	-1.3	-1.3	-1.1	1.3	-1.5	-1.6	-1.2	-1.0	-1.4	-1.1	-1.3	-1.2	-2.1	-1.0	-1.7	-1.5	-1.8	-1.2	-1.6
High blood pressure (mother)	1.5	2.1	5.3	-2.2	-1.3	-1.5	-1.0	-1.2	1.2	-2.1	-0.8	0.3	-1.3	-1.3	-1.4	-1.4	-1.4	-1.5	-1.3	-2.3	-1.9	-1.2	-1.2	-2.0
Number of incorrect matches in round	1.5	2.5	5.5	-1.9	-1.6	-1.3	-1.9	-1.6	1.7	-2.1	-1.6	-0.8	-1.2	-1.6	-1.4	-1.9	-1.4	-1.5	-1.4	-1.8	-2.3	-1.2	-1.9	-1.4
Hair/balding pattern: Pattern 2	1.5	1.9	5.5	1.5	1.4	1.6	0.7	1.2	-1.4	1.6	2.3	1.0	1.7	1.4	1.2	1.5	1.1	0.9	1.3	1.3	1.8	0.4	1.9	1.5
Forced expiratory volume in 1-second (FEV1)	1.5	5.1	10.0	-2.9	-2.4	-2.3	-0.6	-2.6	2.0	-2.7	-2.6	-1.9	-2.2	-2.3	-2.5	-2.0	-2.4	-2.3	-2.7	-3.2	-2.2	-0.4	-2.0	-2.8
Major Depression (MDD)	1.4	1.7	2.8	-1.1	-1.5	-1.5	-1.6	-1.6	1.3	-1.3	-1.1	-0.4	-0.5	-1.5	-1.7	-1.6	-1.6	-0.7	-1.7	-1.2	-1.3	-1.1	-1.5	-1.2
Ever used hormone-replacement therapy (HRT)	1.4	1.7	3.1	1.1	1.7	1.1	0.9	1.3	-1.8	1.4	0.7	0.2	1.1	1.7	1.5	1.5	1.5	1.2	1.5	1.3	1.4	0.9	1.6	1.7
Arm fat mass (right)	1.4	5.8	14.2	-2.4	-2.3	-2.3	-2.9	-1.9	2.4	-2.4	-2.2	-3.8	-2.7	-2.2	-2.4	-2.4	-2.5	-2.3	-2.3	-2.3	-2.3	-3.2	-2.3	-1.7
Arm fat mass (left)	1.4	5.7	14.1	-2.4	-2.3	-2.2	-2.8	-1.9	2.4	-2.3	-2.2	-3.8	-2.7	-2.2	-2.4	-2.4	-2.4	-2.4	-2.2	-2.2	-2.3	-3.1	-2.3	-1.7
LDL Cholesterol	1.3	2.0	4.0	1.4	1.5	1.2	1.1	1.4	-1.8	1.6	2.0	1.1	1.0	1.6	1.2	1.7	1.2	1.0	1.2	1.2	1.9	0.8	1.9	1.9
Heel T-Score	1.3	10.0	18.8	3.7	3.4	3.0	3.1	2.9	-3.2	3.5	2.1	1.7	2.6	3.2	3.4	3.2	3.2	4.3	3.6	3.4	3.2	2.9	3.6	3.8
Diabetes (father)	1.3	1.6	4.1	-0.7	-1.4	-1.7	-2.0	-2.0	1.1	-0.9	-1.1	0.2	0.0	-1.2	-1.9	-1.5	-2.0	-0.4	-1.8	-0.9	-0.6	-0.9	-0.9	-0.4
Multivitamins +/- minerals	1.3	1.6	3.1	-1.6	-1.2	-0.9	-0.6	-1.2	1.0	-1.5	-1.7	-1.8	-1.3	-1.2	-1.4	-1.3	-1.3	-1.4	-1.4	-1.6	-1.3	-1.1	-0.8	-1.2
Pulse wave reflection index	1.3	1.6	2.8	-1.6	-1.3	-1.4	-1.4	-1.5	1.2	-1.6	-0.9	-0.2	-1.3	-1.4	-1.1	-1.2	-1.1	-0.9	-1.4	-1.7	-1.5	-1.4	-1.0	-1.6
Commuting to job workplace: Cycle	1.3	1.5	3.7	-1.1	-1.1	-1.6	-1.9	-1.7	1.1	-0.9	-1.5	-1.6	-1.1	-1.3	-1.1	-1.2	-1.2	-1.0	-1.1	-0.9	-0.9	-1.7	-1.0	-0.6
Impedance of whole body	1.3	6.7	29.8	2.6	2.2	2.5	2.3	2.7	-2.3	1.9	2.1	5.5	3.1	2.2	2.4	2.3	2.5	3.7	2.3	2.0	1.6	3.6	1.6	1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	3.5	-1.6	-0.9	-1.2	-1.0	-0.9	1.0	-1.5	-1.0	-1.2	-1.7	-1.0	-0.9	-0.9	-0.8	-1.2	-0.9	-1.6	-1.4	-1.9	-1.0	-0.9
Supplements: Calcium	1.2	1.3	3.5	-1.2	-1.2	-1.0	-1.1	-0.8	1.1	-1.1	-1.5	-1.9	-1.3	-1.2	-1.3	-1.1	-1.3	-1.2	-1.2	-1.2	-0.8	-1.0	-0.7	-0.9
Trunk fat mass	1.1	4.5	7.2	-2.2	-2.1	-1.9	-2.5	-1.5	2.2	-2.3	-2.3	-2.7	-2.3	-2.0	-2.1	-2.3	-2.1	-1.8	-2.0	-2.2	-2.4	-2.2	-2.5	-1.8
Length of working week for main job	1.1	1.3	3.4	-1.5	-1.1	-1.3	-0.8	-1.3	1.0	-1.6	-1.0	-0.5	-1.1	-1.1	-1.2	-1.0	-1.1	-0.3	-1.2	-1.8	-1.3	-0.5	-1.0	-1.2
Ever highly irritable/argumentative for 2 days	1.1	1.4	2.5	1.2	1.3	1.6	1.5	1.4	-1.3	1.0	0.7	0.2	1.2	1.4	1.4	1.1	1.4	1.1	1.3	1.1	0.7	1.4	0.9	1.0
Exposure to tobacco smoke outside home	1.1	1.5	3.6	-0.5	-1.5	-1.4	-1.7	-1.4	1.4	-0.6	-0.8	-1.0	-0.5	-1.4	-1.7	-1.5	-1.9	-1.4	-1.6	-0.4	-0.5	-1.7	-0.8	-0.3
Medication for pain relief, constipation, heartburn	1.1	1.9	6.9	1.2	1.2	1.4	1.9	1.3	-1.2	0.8	1.0	2.6	1.7	1.1	1.5	1.2	1.6	2.1	1.4	0.9	0.5	1.8	0.6	0.4
Whole body fat mass	1.1	4.5	8.6	-2.2	-2.1	-1.8	-2.6	-1.4	2.1	-2.3	-2.2	-2.9	-2.4	-1.9	-2.0	-2.2	-2.0	-1.9	-1.9	-2.2	-2.4	-2.5	-2.4	-1.8
Friendships satisfaction	1.1	1.4	4.0	-1.5	-1.2	-1.0	-0.9	-1.1	1.4	-1.7	-0.3	-0.1	-0.5	-1.2	-0.9	-1.4	-0.9	-1.0	-0.9	-1.5	-2.0	-0.8	-1.6	-1.3
Medication: Lisinopril	1.1	1.4	3.5	1.2	1.2	1.0	1.0	1.2	-1.2	1.0	0.6	1.3	1.2	1.3	1.2	0.9	0.9	1.6	1.3	1.1	0.8	1.9	1.1	1.6
Birth weight of first child	1.0	1.8	3.4	1.3	1.6	0.7	1.0	1.2	-1.8	1.4	1.2	1.4	1.3	1.5	1.5	1.5	1.5	1.8	1.5	1.3	1.4	0.8	1.4	1.4
High blood pressure (siblings)	1.0	1.4	2.8	1.1	1.3	1.1	1.2	1.3	-1.2	1.1	0.4	1.6	1.1	1.2	1.6	1.2	1.5	1.0	1.5	1.3	0.8	1.7	1.0	0.5
Family relationship satisfaction	1.0	1.3	2.5	0.9	1.1	1.6	1.6	1.3	-0.9	0.9	1.3	1.1	0.6	1.1	1.4	1.2	1.4	0.6	1.4	0.9	0.7	1.5	1.1	0.8
Back pain experienced in last month	1.0	1.4	3.0	-1.7	-1.1	-1.5	-1.2	-1.1	0.9	-1.4	-0.9	-1.2	-1.1	-1.1	-1.3	-1.1	-1.3	-1.3	-1.3	-1.6	-1.2	-0.7	-0.9	-1.1
Number of self-reported non-cancer illnesses	1.0	1.8	7.8	-1.2	-1.1	-1.2	-2.8	-1.1	0.9	-1.1	-1.2	-1.2	-1.3	-1.0	-1.3	-1.2	-1.4	-1.5	-1.2	-1.2	-0.9	-2.3	-0.7	-1.0
Worry (Nagel 2018)	0.9	1.9	4.9	1.6	1.5	1.5	1.3	1.7	-1.1	1.5	2.2	0.3	1.2	1.5	1.4	1.4	1.4	1.0	1.6	1.6	1.4	0.5	1.2	1.5
Age at First Birth	0.9	1.4	3.2	-1.4	-1.3	-0.9	-0.6	-0.8	1.2	-1.7	-0.8	-0.2	-1.2	-1.3	-1.1	-1.2	-1.0	-0.6	-1.1	-1.8	-1.6	-0.8	-1.4	-1.6
Lung FVC	0.9	4.5	7.5	-2.3	-2.3	-2.5	-0.9	-2.7	2.1	-2.3	-2.3	-2.5	-2.2	-2.4	-2.4	-2.1	-2.4	-1.8	-2.5	-2.3	-2.0	-1.2	-1.6	-1.8
Fed-up feelings	0.9	1.6	3.3	-1.1	-1.6	-1.2	-0.9	-1.3	1.4	-1.3	-1.1	-1.8	-1.2	-1.5	-1.5	-1.3	-1.4	-1.0	-1.5	-1.4	-1.2	-0.6	-1.2	-1.4
Relative age voice broke	0.9	1.4	2.8	-1.3	-1.4	-1.3	-0.8	-1.0	1.5	-1.2	-1.0	-0.9	-1.4	-1.4	-1.2	-1.2	-1.2	-1.4	-1.2	-1.2	-1.1	-0.9	-1.1	-1.7
Body mass index (BMI)	0.9	4.0	17.4	-1.8	-1.6	-1.6	-2.5	-1.4	1.7	-1.6	-1.6	-4.2	-2.6	-1.5	-1.8	-1.8	-1.8	-2.3	-1.6	-1.5	-1.6	-3.2	-1.6	-1.0
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	2.3	1.2	1.1	1.2	1.2	1.1	-1.3	1.1	1.3	0.9	1.5	1.2	1.2	1.3	1.2	1.2	1.1	0.9	1.2	1.2	1.4	0.9
Father’s age at death	0.9	1.2	2.4	-1.2	-1.1	-1.1	-1.5	-1.2	1.0	-1.2	-1.0	-0.2	-1.1	-1.2	-1.0	-1.2	-1.0	-0.5	-1.0	-1.2	-1.3	-1.3	-1.4	-1.2
Standing height	0.9	9.0	19.0	-3.8	-3.3	-3.1	-0.8	-2.7	3.1	-3.8	-3.7	-0.8	-1.7	-3.2	-2.9	-2.9	-2.9	-2.6	-3.1	-4.0	-3.6	0.2	-3.6	-4.4
Mouth/teeth dental problems: Bleeding gums	0.9	1.1	2.4	-1.2	-1.1	-1.6	-0.5	-1.4	1.0	-0.9	-1.2	-0.8	-1.4	-1.2	-1.1	-1.0	-1.1	-1.1	-1.2	-1.0	-0.8	-0.7	-0.8	-1.3
Knee pain experienced in last month	0.9	1.4	3.7	-1.9	-1.0	-1.8	-0.6	-1.0	0.8	-1.6	-0.6	-0.6	-0.7	-1.1	-1.1	-1.1	-1.1	-0.7	-1.1	-1.9	-1.4	-0.9	-0.9	-1.6
Mood swings	0.9	1.6	3.5	-1.3	-1.5	-1.2	-0.8	-1.1	1.5	-1.4	-1.0	-1.4	-1.0	-1.5	-1.1	-1.3	-1.0	-1.0	-1.2	-1.4	-1.6	-0.9	-1.5	-1.9
Long-standing illness, disability or infirmity	0.9	1.4	3.1	-1.3	-1.2	-1.4	-1.7	-1.1	0.8	-1.4	-1.1	-0.6	-0.4	-1.1	-1.4	-1.1	-1.4	-1.1	-1.4	-1.5	-1.2	-1.4	-0.9	-1.1
Osteoporosis (self-reported)	0.9	1.1	5.0	-0.6	-0.8	-1.0	-2.2	-1.0	0.7	-0.4	-0.9	-1.7	-0.6	-0.8	-1.1	-0.9	-1.2	-1.5	-1.0	-0.3	-0.3	-1.9	-0.4	-0.3
Depression (Nagel 2018)	0.8	1.2	2.5	1.2	1.1	0.9	1.4	1.2	-1.1	1.1	0.6	0.1	0.8	1.1	1.2	1.4	1.3	1.2	1.0	0.7	1.2	1.4	1.6	0.8
Ovarian Cancer	0.8	1.0	2.7	1.3	0.8	1.1	1.0	1.0	-0.8	1.1	1.0	1.4	1.7	0.8	0.8	1.0	0.8	0.9	0.8	0.9	1.2	1.2	1.0	0.6
Sensitivity / hurt feelings	0.8	1.3	2.4	1.1	1.2	1.4	1.6	1.4	-0.9	1.3	0.9	-0.9	0.2	1.2	1.4	1.5	1.5	0.4	1.4	1.1	1.3	0.9	1.1	1.0
Hearing difficulty/problems: Yes	0.8	1.2	3.5	-1.5	-1.1	-0.6	-0.3	-0.5	1.3	-1.6	-0.3	0.0	-1.1	-1.1	-0.8	-1.1	-0.7	-0.9	-0.8	-1.6	-1.7	-0.5	-1.6	-1.9
Maternal smoking around birth	0.8	1.2	2.7	0.7	1.1	0.7	1.6	1.2	-1.1	0.8	0.6	0.6	1.5	1.1	1.2	1.1	1.3	1.5	1.2	0.8	0.7	1.5	1.0	1.0
Taking other prescription medications	0.8	1.3	3.2	-1.4	-0.8	-0.8	-1.6	-0.7	0.8	-1.3	-1.6	-1.8	-1.1	-0.8	-0.8	-1.0	-1.0	-1.5	-0.8	-1.3	-1.2	-1.5	-0.9	-0.5
Stomach or abdominal pain in last month	0.8	1.0	2.6	-1.0	-1.0	-0.8	-1.6	-0.8	1.0	-0.9	-0.9	-1.0	-0.9	-0.9	-1.0	-0.8	-1.0	-1.2	-0.9	-1.0	-0.7	-1.2	-0.9	-1.2
Mouth/teeth dental problems	0.8	1.3	2.9	1.0	1.2	1.7	1.1	1.1	-1.3	1.0	0.9	1.0	1.2	1.2	1.2	1.4	1.2	0.9	1.2	0.7	1.1	1.5	1.2	0.8
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	3.2	1.5	1.0	0.8	1.0	0.4	-0.9	1.6	0.4	-0.3	0.7	1.0	0.8	1.1	0.7	0.7	0.8	1.4	1.8	0.3	1.4	1.7
Impedance of arm (right)	0.8	3.9	15.8	2.1	1.7	1.7	1.2	1.9	-1.7	1.6	1.3	4.0	2.6	1.7	1.7	1.7	1.7	3.3	1.6	1.6	1.5	2.5	1.6	1.3
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	2.2	-1.1	-1.1	-1.5	-0.9	-1.1	1.0	-0.9	-0.5	0.2	-0.1	-1.0	-1.2	-1.1	-1.2	-1.0	-1.2	-0.8	-0.8	-0.2	-0.6	-1.5
Chronic bronchitis/emphysema (mother)	0.8	0.9	2.2	0.5	1.2	0.6	0.8	0.9	-1.3	0.9	0.5	0.9	1.1	1.2	1.1	1.2	1.1	0.8	1.1	0.6	1.0	0.9	1.5	0.6
Angina (self-reported)	0.8	1.0	3.0	-1.1	-0.6	-1.0	-1.7	-1.0	0.7	-0.7	-0.8	-1.5	-1.3	-0.4	-1.0	-0.7	-1.0	-1.6	-1.0	-0.9	-0.4	-1.7	-0.6	-0.7
Arm fat percentage (left)	0.8	3.3	9.3	-1.4	-1.6	-1.5	-2.9	-1.2	1.8	-1.6	-1.4	-3.0	-2.3	-1.6	-1.7	-1.9	-1.8	-1.4	-1.5	-1.3	-1.7	-3.1	-1.8	-0.9
Guilty feelings	0.8	1.2	2.8	0.5	1.4	1.4	1.5	1.4	-1.1	0.8	0.7	-0.3	0.3	1.4	1.5	1.6	1.7	0.7	1.5	0.3	0.9	0.9	1.4	0.7
Diastolic blood pressure, automated reading	0.8	2.4	5.3	1.2	2.0	1.3	0.5	1.7	-2.3	1.4	1.9	1.2	1.0	2.1	1.6	2.0	1.6	1.7	1.5	1.1	1.8	0.7	2.2	0.7
Cholesterol lowering medication	0.8	1.2	4.2	1.4	1.2	0.9	0.8	0.9	-1.0	1.6	0.6	-0.6	0.7	1.1	1.0	0.8	0.8	0.3	1.3	1.8	1.4	0.1	1.1	2.0
Prostate Cancer	0.7	1.0	1.6	-1.2	-0.9	-1.1	-0.9	-1.0	0.9	-1.1	-0.7	-1.0	-0.9	-0.9	-1.0	-1.1	-1.1	-1.2	-1.0	-1.0	-1.1	-1.3	-0.8	-1.1
Mean Putamen Volume	0.7	0.8	2.9	-0.5	-1.0	-1.4	-0.2	-1.7	0.8	-0.3	-0.2	-0.5	0.1	-1.0	-1.4	-1.0	-1.5	-1.0	-1.3	-0.3	-0.1	-1.0	-0.5	-0.1
Triglycerides	0.7	1.2	3.0	1.4	1.3	1.0	0.6	0.8	-1.5	1.4	1.1	-0.4	0.5	1.3	1.1	1.0	0.9	0.2	1.2	1.6	1.3	-0.1	1.1	1.7
BMI	0.7	3.8	13.2	-1.9	-1.6	-1.6	-2.4	-1.8	1.6	-1.9	-1.5	-3.6	-2.4	-1.6	-1.9	-1.9	-2.0	-2.0	-1.8	-1.9	-1.8	-2.8	-1.5	-0.9
Sitting height	0.7	4.8	8.6	-2.7	-2.2	-2.3	-1.3	-2.1	2.2	-2.8	-2.9	-1.4	-1.8	-2.2	-2.0	-2.2	-2.0	-1.7	-2.1	-2.8	-2.8	-0.6	-2.7	-2.9
Leg fat mass (right)	0.7	2.6	8.6	-1.6	-1.3	-1.1	-2.1	-0.8	1.5	-1.6	-1.7	-2.9	-2.1	-1.3	-1.3	-1.5	-1.3	-1.7	-1.2	-1.4	-1.7	-2.2	-1.7	-1.2
Alcohol intake frequency.	0.7	1.6	3.3	0.4	1.3	1.6	1.6	1.7	-1.4	0.5	1.3	1.7	1.8	1.2	1.6	1.3	1.7	1.0	1.6	0.4	0.4	1.4	0.8	0.4
Eye problems/disorders: Cataract	0.7	0.8	2.3	1.2	0.5	0.1	0.9	0.1	-0.4	1.2	0.5	1.2	1.5	0.5	0.3	0.7	0.2	1.4	0.3	1.0	1.4	0.8	0.8	1.2
Osteoarthritis (self-reported)	0.7	0.9	3.5	-0.6	-0.6	-0.6	-1.7	-0.4	0.5	-0.6	-1.1	-1.9	-0.7	-0.5	-0.8	-0.9	-0.8	-1.3	-0.6	-0.4	-0.8	-1.7	-0.9	-0.3
Medication: Gliclazide	0.7	0.8	2.4	0.4	1.2	1.0	-0.7	1.1	-1.5	0.6	0.1	-0.3	0.3	1.4	0.9	1.0	0.8	0.4	0.9	0.4	0.7	0.1	1.5	1.2
Ever taken oral contraceptive pill	0.7	0.7	2.4	-0.7	-1.1	-0.9	-0.4	-0.9	0.9	-0.9	-0.8	-0.3	-0.1	-1.0	-1.1	-1.0	-1.1	-0.3	-1.1	-0.9	-0.8	0.3	-0.9	-1.5
Leg fat mass (left)	0.7	2.9	9.3	-1.6	-1.5	-1.2	-2.2	-0.9	1.5	-1.7	-1.9	-3.0	-2.2	-1.4	-1.5	-1.6	-1.4	-1.8	-1.4	-1.6	-1.8	-2.2	-1.8	-1.3
Relative age of first facial hair	0.6	1.3	3.9	-1.1	-1.0	-0.7	-1.0	-0.9	1.1	-1.0	-1.5	-2.0	-2.0	-1.0	-1.1	-0.9	-1.1	-1.3	-1.0	-1.2	-0.8	-0.6	-0.7	-1.0
Angina	0.6	0.8	2.2	-1.1	-0.5	-0.8	-1.5	-0.7	0.4	-0.7	-0.7	-1.2	-1.1	-0.3	-0.8	-0.5	-0.8	-1.5	-0.8	-0.9	-0.4	-1.4	-0.5	-0.7
Arm fat percentage (right)	0.6	2.2	7.8	-1.0	-1.2	-1.2	-2.7	-0.9	1.3	-1.1	-1.1	-2.7	-1.9	-1.1	-1.3	-1.4	-1.4	-1.0	-1.2	-1.0	-1.2	-2.8	-1.2	-0.5
Breastfed as a baby	0.6	0.8	2.0	0.6	1.0	1.0	1.4	1.2	-0.9	0.9	0.7	0.6	0.5	0.9	1.2	0.9	1.2	0.2	1.3	0.9	0.6	0.9	0.7	0.5
Number of full brothers	0.6	0.7	2.0	-0.8	-0.9	-0.7	-0.0	-0.8	1.0	-0.7	-1.0	-1.4	-1.4	-0.8	-0.7	-0.7	-0.7	-1.4	-0.7	-0.7	-0.7	-0.5	-0.8	-0.7
Number of children fathered	0.6	0.7	2.3	-0.8	-0.7	-0.4	-0.3	-0.1	1.1	-0.9	-0.6	-1.1	-1.5	-0.8	-0.3	-0.7	-0.3	-1.1	-0.2	-0.8	-1.1	-0.2	-1.1	-1.3
Ever had bowel cancer screening	0.6	0.7	1.8	0.2	1.1	1.2	0.0	1.4	-1.0	0.2	-0.2	-0.2	-0.3	1.2	1.3	1.0	1.3	1.1	1.2	0.2	0.1	0.4	0.6	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	3.0	-0.9	-0.9	-1.7	-0.3	-1.3	0.7	-0.6	-0.9	-0.3	-0.1	-1.0	-1.0	-0.9	-1.0	-0.8	-1.0	-0.6	-0.5	-0.6	-0.8	-0.7
Illnesses of father: None of the above (group 1)	0.6	0.8	2.2	-1.4	-0.9	-0.7	-0.3	-0.8	0.7	-1.4	-0.1	-0.1	-0.7	-0.9	-0.5	-0.8	-0.4	-1.1	-0.6	-1.3	-1.5	-0.8	-1.1	-1.2
Miserableness	0.6	1.0	2.2	-0.9	-1.2	-1.1	-0.5	-1.1	1.4	-0.9	-0.9	-1.5	-1.1	-1.1	-1.0	-0.9	-0.9	-0.8	-1.1	-1.0	-0.9	-1.1	-0.8	-1.2
Medication: Paracetamol	0.6	1.0	4.4	-0.4	-0.9	-1.0	-1.6	-1.2	0.8	-0.3	-0.7	-2.1	-0.7	-0.8	-1.3	-0.8	-1.4	-0.9	-1.2	-0.3	0.0	-1.5	0.0	0.5
Depressed Affect (Nagel 2018)	0.5	1.0	2.0	-0.9	-1.2	-1.1	-0.5	-0.8	1.4	-1.1	-0.5	-1.2	-0.9	-1.3	-0.8	-1.0	-0.7	-0.8	-0.8	-1.1	-1.1	-0.8	-1.1	-1.4
Blood Platelet Count	0.5	6.3	13.6	2.8	2.9	2.3	2.0	2.1	-3.0	2.8	2.1	0.7	2.4	2.8	2.5	2.8	2.3	2.7	2.5	2.6	3.0	1.1	3.1	3.7
Height	0.5	9.4	18.4	-3.8	-3.3	-3.1	-0.6	-2.7	3.0	-3.7	-4.0	-1.2	-1.9	-3.2	-3.2	-3.1	-3.1	-3.2	-3.4	-3.6	-3.5	0.2	-3.8	-4.3
Allergy or Eczema	0.5	1.2	2.5	-0.8	-1.2	-0.7	-1.3	-1.2	1.6	-1.0	-1.0	-0.9	-1.3	-1.2	-1.2	-1.2	-1.2	-0.9	-1.1	-1.0	-0.9	-1.5	-1.2	-0.6
Vitamin and mineral supplements	0.5	0.7	1.6	1.1	0.9	0.7	0.0	1.0	-0.8	1.0	1.3	0.9	0.7	0.8	1.0	1.0	1.1	0.7	1.0	1.1	0.9	0.3	0.7	0.2
Pack years adult smoking proportion	0.5	0.7	2.5	-1.0	-0.8	-0.8	-0.8	-0.7	0.9	-0.7	-0.9	-1.1	-0.5	-0.8	-0.9	-1.0	-1.0	-1.6	-0.7	-0.7	-0.7	-0.9	-0.5	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	2.0	1.1	0.6	0.4	1.3	0.5	-0.8	1.0	0.7	0.1	0.7	0.7	0.6	1.1	0.7	1.4	0.4	0.7	1.3	1.1	1.2	0.7
Waist circumference	0.5	1.8	9.2	-1.2	-1.1	-1.1	-1.7	-0.8	1.1	-1.1	-1.3	-3.0	-1.4	-1.0	-1.2	-1.3	-1.3	-1.5	-1.0	-1.0	-1.1	-2.1	-1.3	-0.5
Hip circumference	0.5	2.3	5.5	-1.6	-1.5	-1.3	-1.3	-0.8	1.7	-1.8	-1.6	-2.4	-1.5	-1.4	-1.5	-1.6	-1.5	-1.3	-1.4	-1.8	-1.8	-1.4	-1.7	-1.4
Time employed in main current job	0.5	0.5	2.5	-0.1	0.7	0.2	0.8	0.5	-0.9	-0.1	0.9	1.6	0.9	0.7	0.5	0.7	0.5	1.2	0.4	-0.4	0.2	1.2	0.7	0.4
Hair/balding pattern: Pattern 3	0.5	0.7	2.2	1.3	0.9	1.0	0.1	1.0	-0.8	1.0	0.3	1.2	0.5	0.8	1.0	0.6	1.0	1.0	1.0	1.5	0.6	0.5	0.3	0.7
Qualifications: A levels/AS levels or equivalent	0.5	1.0	2.1	-0.9	-1.2	-1.1	-1.0	-1.1	0.9	-0.8	-0.9	-0.2	-0.4	-1.1	-1.3	-0.9	-1.4	-1.4	-1.4	-1.1	-0.5	-0.5	-0.7	-1.4
Tense / ‘highly strung’	0.5	0.8	1.7	1.2	0.9	0.9	1.1	0.6	-0.8	1.2	1.0	0.2	1.0	1.0	0.6	0.9	0.7	0.7	0.7	1.2	1.2	0.7	1.1	1.3
Hair/balding pattern: Pattern 4	0.5	1.3	2.1	-1.2	-1.3	-1.4	-0.7	-0.9	1.2	-1.4	-1.4	-1.0	-1.4	-1.2	-1.1	-1.2	-1.0	-0.3	-1.2	-1.3	-1.5	-0.7	-1.4	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	2.2	-0.1	0.7	0.8	1.5	1.1	-0.6	0.1	0.4	0.3	1.0	0.7	1.1	1.0	1.2	0.2	1.0	-0.2	0.0	1.4	0.6	-0.2
Health satisfaction	0.5	0.6	1.7	0.3	0.8	0.8	1.3	1.2	-0.9	0.3	0.6	-0.0	0.8	0.9	0.9	0.9	1.0	0.4	1.0	-0.0	0.4	1.3	0.7	-0.4
Eye problems/disorders: None of the above	0.5	0.6	2.3	-0.9	-0.7	0.3	-0.5	-0.0	0.7	-1.1	-0.1	-0.4	-1.0	-0.6	-0.2	-0.7	-0.1	-1.0	-0.3	-0.8	-1.5	-0.5	-1.3	-1.5
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.3	1.0	0.9	0.8	0.0	0.7	-1.1	1.0	0.8	0.1	0.4	0.9	0.8	0.9	0.7	0.4	0.7	1.1	1.0	-0.0	0.5	1.0
Medication for cholesterol	0.5	0.8	2.7	-0.9	-1.0	-0.7	0.0	-0.8	0.7	-1.1	0.4	1.6	0.4	-1.0	-0.8	-0.9	-0.6	-0.3	-0.9	-1.0	-1.1	0.1	-1.0	-1.4
Smoking status: Current	0.5	0.9	2.1	0.8	0.9	0.5	1.1	1.0	-0.7	1.0	1.5	0.4	1.3	0.9	1.1	0.9	1.0	0.5	1.1	0.9	0.8	0.9	1.0	1.2
Illnesses of father: High blood pressure	0.5	0.6	1.3	-0.6	-0.9	-0.4	-1.1	-0.5	1.0	-0.7	-0.9	-0.4	-0.7	-0.9	-0.8	-0.9	-0.8	-0.5	-0.7	-0.5	-0.8	-0.6	-1.0	-0.9
Age started oral contraceptive pill	0.5	0.6	2.0	0.5	0.7	0.9	1.4	1.0	-0.5	0.6	0.4	0.7	0.5	0.7	0.9	0.6	0.9	0.6	1.1	0.7	0.3	1.3	0.3	0.9
Alzheimer’s Disease (in mother)	0.4	0.5	1.4	-0.8	-0.8	-0.6	0.2	-0.9	0.8	-1.0	-0.5	0.5	-0.1	-0.9	-0.5	-0.7	-0.5	-0.3	-0.7	-1.0	-1.1	0.3	-0.8	-1.2
Crohns Disease (2012)	0.4	0.6	1.7	-1.0	-0.7	-1.3	-0.5	-1.1	0.4	-0.9	-0.6	-0.2	-0.3	-0.6	-0.9	-0.5	-0.9	0.2	-1.1	-1.3	-0.5	-0.7	-0.4	-0.8
Smoking Status	0.4	1.0	3.9	-0.7	-1.1	-1.7	-0.6	-1.3	1.1	-0.4	-0.9	-2.0	-0.4	-1.1	-1.1	-1.1	-1.2	-0.9	-1.1	-0.3	-0.4	-0.9	-0.7	-0.3
Number of treatments/medications taken	0.4	0.7	2.3	-0.8	-0.5	-0.8	-1.5	-0.5	0.7	-0.7	-1.0	-1.1	-0.9	-0.5	-0.7	-0.8	-0.9	-0.9	-0.6	-0.8	-0.7	-1.4	-0.4	0.0
Diabetes (mother)	0.4	0.5	1.2	0.9	0.7	0.9	-0.6	1.0	-0.8	0.7	0.9	1.1	0.3	0.7	0.8	0.7	0.7	0.7	0.8	0.8	0.7	0.2	0.8	0.4
Trunk fat percentage	0.4	1.7	4.4	-1.1	-1.3	-1.0	-2.1	-0.5	1.4	-1.4	-1.3	-1.6	-1.4	-1.2	-1.2	-1.5	-1.2	-0.7	-1.0	-1.2	-1.7	-1.7	-1.7	-0.8
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.4	-0.9	-0.6	-0.5	-0.4	-0.8	0.7	-1.1	-0.4	-0.5	-0.3	-0.5	-0.6	-0.8	-0.5	-0.2	-0.6	-0.9	-1.2	-0.9	-1.2	-0.5
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.0	0.3	0.9	0.6	0.7	0.7	-1.0	0.5	0.4	-0.5	0.0	0.9	0.8	0.7	0.8	0.5	0.8	0.5	0.4	0.8	0.6	0.6
Serious illness, injury or assault to yourself	0.4	0.5	1.5	-1.1	-0.5	-0.6	-1.2	-0.4	0.5	-0.9	-0.6	0.1	-0.3	-0.5	-0.6	-0.5	-0.6	-0.8	-0.6	-1.2	-0.7	-0.9	-0.2	-0.5
Hayfever, allergic rhinitis or eczema	0.4	0.9	1.5	-0.7	-1.0	-0.7	-1.0	-1.2	1.2	-0.8	-1.0	-1.0	-1.1	-1.0	-1.2	-0.9	-1.2	-0.9	-1.1	-1.0	-0.6	-1.0	-0.6	-0.4
Medication: Atenolol	0.4	0.5	2.1	1.1	0.7	0.5	-0.1	0.4	-0.7	1.1	0.2	0.0	0.1	0.7	0.5	0.4	0.4	0.4	0.7	1.2	0.9	0.1	0.4	1.5
Ever unenthusiastic/disinterested for a whole week	0.4	0.4	1.8	-0.6	0.0	0.0	0.6	0.1	-0.1	-0.7	0.8	1.3	1.2	-0.1	0.3	0.1	0.4	1.2	0.2	-0.9	-0.7	0.7	-0.2	-0.9
Alcohol intake versus 10 years previously	0.4	0.7	1.6	-0.9	-0.8	-0.6	-0.8	-0.7	0.7	-0.9	-0.6	-0.3	-1.0	-0.7	-0.8	-0.9	-0.8	-1.3	-0.8	-0.9	-0.9	-0.7	-1.0	-1.0
Pulse rate	0.4	0.6	2.0	0.3	0.8	0.1	1.1	0.8	-1.0	0.4	0.1	1.4	1.1	0.9	0.6	0.8	0.7	1.1	0.6	0.1	0.6	1.1	0.9	0.2
Prospective memory result	0.4	0.5	1.2	0.4	0.7	0.6	0.8	0.6	-0.4	0.8	1.1	0.6	0.4	0.6	0.9	0.7	0.8	0.1	0.9	0.9	0.6	0.4	0.4	0.9
Peak expiratory flow (PEF)	0.4	0.9	2.4	-1.0	-1.1	-1.4	-0.0	-1.4	0.7	-1.0	-1.0	-0.2	-0.2	-1.0	-1.4	-0.8	-1.3	-0.2	-1.5	-1.4	-0.5	0.5	-0.6	-1.1
Medication: Paracetamol	0.4	0.6	3.8	-0.4	-0.6	-0.9	-1.3	-0.9	0.3	-0.1	-0.5	-1.9	-0.1	-0.5	-1.0	-0.4	-1.0	-0.9	-0.9	-0.3	0.3	-1.1	0.3	0.5
Glaucoma (self-reported)	0.4	0.5	0.9	0.7	0.8	0.9	0.1	0.8	-0.7	0.8	0.9	-0.1	0.5	0.7	0.8	0.6	0.7	0.2	0.9	0.8	0.7	0.1	0.7	0.8
Medication: Amlodipine	0.4	0.5	1.0	-0.8	-0.6	-0.6	-1.0	-0.6	0.7	-0.8	-1.0	-0.8	-0.6	-0.6	-0.7	-0.7	-0.7	-0.4	-0.6	-1.0	-0.8	-0.6	-0.6	-0.4
Migraine (self-reported)	0.4	0.4	1.2	-1.0	-0.5	-0.5	-0.4	-0.5	0.4	-1.0	-0.8	-0.5	-0.4	-0.5	-0.6	-0.5	-0.5	-0.9	-0.7	-1.1	-0.9	-0.6	-0.6	-0.7
Diabetes diagnosed by doctor	0.4	0.7	3.9	1.1	0.9	0.7	-0.5	0.6	-1.1	1.1	0.2	-0.3	0.4	1.0	0.4	0.6	0.3	0.2	0.5	1.3	1.1	-0.4	1.0	2.0
Tinnitus: Yes, now most or all of the time	0.4	0.4	1.0	0.6	0.7	1.0	0.5	0.8	-0.5	0.5	1.0	0.6	0.5	0.8	0.7	0.7	0.7	0.8	0.7	0.5	0.5	0.5	0.6	0.7
Medication: Blood pressure	0.4	0.7	2.4	0.9	0.9	1.0	-0.6	0.9	-0.8	0.8	0.1	-1.6	-1.0	1.0	0.7	0.6	0.6	-0.2	0.9	1.0	0.7	-0.8	0.6	1.4
Vascular/heart problems diagnosed by doctor	0.4	1.2	6.7	0.6	0.7	0.6	2.6	0.6	-0.7	0.6	0.7	1.4	1.4	0.5	0.9	0.9	1.0	1.4	0.8	0.5	0.6	2.4	0.6	0.2
Bipolar Disorder (2011)	0.3	0.3	0.9	-0.4	-0.5	-0.5	-0.6	-0.7	0.4	-0.5	0.3	0.3	-0.2	-0.4	-0.6	-0.2	-0.5	0.6	-0.8	-0.7	-0.1	-0.3	-0.2	-1.0
HbA1C	0.3	0.4	1.0	0.7	0.6	0.2	0.6	0.5	-0.4	0.7	0.4	0.8	0.6	0.6	0.7	0.5	0.6	0.4	0.7	0.8	0.6	0.6	0.7	1.0
Average weekly spirits intake	0.3	0.4	1.3	0.4	0.8	0.5	-0.3	0.6	-0.6	0.7	-0.0	-1.1	0.4	0.6	0.7	0.5	0.6	-0.1	0.8	0.9	0.5	-0.7	0.4	0.8
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.0	0.3	-0.4	-0.8	-1.0	-0.9	0.3	0.3	-0.7	-0.3	0.1	-0.3	-0.5	-0.4	-0.7	-0.3	-0.5	0.5	0.4	-0.9	0.2	1.0
Medication: Metformin	0.3	0.5	2.2	0.6	0.9	0.6	-0.4	0.6	-1.2	0.7	-0.2	-0.7	0.3	0.9	0.4	0.5	0.3	-0.1	0.5	0.8	0.7	-0.4	0.8	1.5
Hand grip strength (right)	0.3	0.9	5.1	0.2	0.3	0.1	1.6	0.1	-0.6	-0.1	0.4	2.1	1.0	0.3	0.2	0.7	0.3	2.0	-0.1	-0.6	0.3	2.3	0.4	-0.5
Current tobacco smoking	0.3	0.5	2.0	0.6	0.6	0.2	0.9	0.7	-0.4	0.8	1.4	0.3	1.2	0.6	0.7	0.6	0.6	0.1	0.8	0.8	0.7	0.8	0.8	1.0
Average weekly fortified wine intake	0.3	0.3	0.9	-0.0	0.6	0.5	0.7	0.8	-0.6	0.1	1.0	0.6	0.5	0.6	0.7	0.7	0.6	0.5	0.6	-0.1	0.2	0.8	0.6	0.3
Medication: Levothyroxine sodium	0.3	0.5	3.1	0.1	-0.5	-0.0	-1.8	-0.7	0.5	-0.3	-0.9	-0.5	-0.7	-0.4	-0.7	-0.9	-0.7	0.2	-0.6	0.1	-0.5	-1.4	-0.9	0.7
Qualifications: None of the above	0.3	0.6	2.1	0.7	0.8	0.6	0.6	0.9	-0.4	0.7	1.4	0.8	0.4	0.7	1.1	0.6	1.2	0.7	1.2	1.0	0.3	-0.4	0.3	0.9
Heart attack	0.3	0.4	1.3	-0.1	-0.6	-0.9	-1.1	-0.6	0.8	-0.1	-1.1	-0.3	0.7	-0.6	-0.6	-0.9	-0.7	-0.4	-0.6	0.4	-0.3	-0.6	-1.0	0.1
Medication: Ramipril	0.3	0.4	1.6	-0.3	-0.4	-0.6	-0.9	-0.7	0.4	-0.2	-1.1	-1.3	-0.9	-0.3	-0.7	-0.5	-0.7	-0.8	-0.5	-0.2	-0.1	-0.6	-0.1	-0.2
Falls in the last year	0.3	0.4	2.0	-0.8	-0.5	-0.8	-1.4	-0.5	0.4	-0.9	-0.4	0.0	-0.3	-0.5	-0.5	-0.6	-0.7	0.1	-0.5	-1.0	-0.8	-0.6	-0.5	-0.4
Lung cancer (father)	0.3	0.3	1.3	0.6	0.3	0.5	-0.5	0.5	0.0	0.6	0.1	-1.0	0.2	0.2	0.5	0.0	0.4	-0.4	0.7	1.0	0.1	-0.8	-0.2	1.1
Impedance of arm (left)	0.3	1.4	12.2	1.1	0.5	0.7	0.5	0.9	-0.4	0.5	0.9	3.5	1.7	0.5	0.7	0.5	0.7	2.2	0.7	0.7	0.2	1.6	0.2	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	1.4	-0.4	0.6	0.3	1.1	0.9	-0.7	-0.0	1.0	0.6	1.2	0.5	0.7	0.8	0.8	-0.1	0.6	-0.5	0.2	0.9	0.8	-0.3
Body fat percentage	0.3	1.2	4.2	-0.7	-0.9	-0.5	-2.0	-0.1	1.0	-1.0	-1.0	-1.7	-1.4	-0.8	-0.8	-1.1	-0.8	-0.6	-0.6	-0.7	-1.3	-1.9	-1.4	-0.4
Medication: Allopurinol	0.3	0.4	2.3	-0.4	0.5	0.8	0.9	1.0	-0.4	-0.6	-0.2	0.4	0.4	0.6	0.6	0.2	0.7	0.2	0.6	-0.5	-0.8	1.5	-0.3	-0.5
Medication: Seretide 50 evohaler	0.3	0.4	2.7	-0.5	-0.7	-0.2	-0.0	-0.5	0.6	-0.7	-1.6	-0.6	-0.4	-0.6	-0.6	-0.5	-0.6	-0.4	-0.7	-0.7	-0.6	0.6	-0.4	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	1.1	0.1	0.7	0.7	0.0	0.8	-0.4	0.4	1.1	-0.4	-0.1	0.7	0.8	0.7	0.8	-0.1	0.9	0.2	0.4	-0.4	0.8	0.6
Comparative height size at age 10	0.3	1.4	4.5	-1.4	-1.1	-0.8	0.9	-0.7	1.0	-1.5	-1.9	0.4	-0.2	-1.1	-0.8	-1.0	-0.7	-0.8	-0.8	-1.6	-1.6	1.5	-1.5	-2.1
Medication: Aspirin	0.3	0.3	1.8	0.2	0.2	-0.0	-1.0	-0.1	-0.2	0.4	0.0	-1.2	-0.7	0.4	-0.1	-0.0	-0.2	-0.8	-0.1	0.6	0.4	-1.3	0.2	1.1
Illnesses of siblings: Diabetes	0.3	0.4	2.0	0.4	-0.1	-0.1	0.4	0.1	0.0	0.0	-0.8	1.4	1.0	-0.1	-0.0	-0.4	-0.1	1.3	0.0	0.5	-0.3	1.0	-0.7	0.5
Loneliness, isolation	0.3	0.5	1.8	0.8	0.4	0.5	0.9	0.7	-0.3	0.8	0.8	0.3	1.1	0.4	0.5	0.6	0.5	0.6	0.6	0.7	0.8	1.3	0.5	0.7
Medication: Aspirin	0.3	0.4	1.7	0.4	0.5	0.1	-0.6	0.1	-0.5	0.7	0.5	-0.8	-0.3	0.6	0.1	0.3	-0.0	-0.4	0.1	0.7	0.8	-1.1	0.6	1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	1.7	0.8	0.9	0.8	1.3	0.7	-0.8	1.0	1.0	0.1	0.3	0.8	1.0	1.0	1.1	0.4	1.0	0.9	1.0	0.6	0.9	0.6
Financial situation satisfaction	0.3	0.4	2.0	-0.1	-0.8	-0.2	0.0	-0.4	1.0	-0.3	-0.9	-1.4	-1.0	-0.8	-0.4	-0.7	-0.4	-0.6	-0.3	-0.1	-0.5	-0.4	-0.5	0.1
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.8	-0.6	-0.4	-0.4	-0.7	-0.7	0.3	-0.5	0.1	-1.2	-0.7	-0.3	-0.6	-0.7	-0.8	-0.9	-0.5	-0.4	-0.4	-1.4	-0.3	0.2
Irritability	0.3	0.5	1.6	-0.4	-1.1	-0.2	0.0	-0.5	1.2	-0.8	-0.1	-0.6	-0.6	-0.9	-0.7	-0.9	-0.6	-0.7	-0.7	-0.7	-1.0	-0.5	-1.3	-0.7
Myopia	0.3	0.4	2.5	-0.6	-0.3	0.3	-0.5	0.1	0.1	-0.9	0.0	1.2	0.4	-0.3	-0.2	-0.4	-0.0	0.2	-0.2	-0.8	-1.1	0.5	-0.8	-1.6
Basal cell carcinoma (self-reported)	0.3	0.4	4.5	0.3	-0.3	0.1	-0.2	0.4	0.1	0.0	0.8	2.1	1.1	-0.2	-0.1	-0.2	-0.1	0.8	-0.1	0.1	-0.1	0.6	-0.2	-0.4
Bipolar Disorder (2018)	0.2	0.4	1.3	0.4	0.8	0.8	0.3	0.4	-1.0	0.4	1.1	0.2	-0.1	0.8	0.6	0.7	0.7	1.1	0.5	0.3	0.5	0.5	0.4	0.4
Alzheimer’s Disease (in father)	0.2	0.2	1.4	0.3	0.2	0.4	0.4	0.6	-0.0	0.0	-0.3	0.4	0.2	0.2	0.6	0.1	0.5	0.9	0.6	0.2	-0.3	1.2	0.0	0.7
Breast Cancer	0.2	0.5	1.6	0.9	0.5	0.9	1.0	0.5	-0.1	0.9	0.3	0.3	0.3	0.4	0.7	0.3	0.5	0.2	0.8	1.1	0.5	1.1	0.4	1.3
Neuroticism (2016)	0.2	0.3	0.5	0.1	0.6	0.4	0.6	0.7	-0.7	0.2	-0.1	-0.5	0.5	0.7	0.6	0.7	0.7	0.5	0.5	0.0	0.3	0.4	0.4	0.5
Cardiovascular Disease	0.2	0.7	1.5	0.9	0.9	1.1	-0.7	1.1	-1.0	0.9	0.9	-0.3	-0.1	1.0	0.8	1.0	0.7	0.3	0.9	0.8	1.1	-0.4	1.2	0.8
Hypothyroidism (self reported)	0.2	0.4	2.2	0.6	-0.6	-0.3	-1.5	-0.8	0.4	0.2	-0.8	-0.1	0.3	-0.5	-0.9	-0.9	-0.9	0.4	-0.7	0.7	0.0	-0.5	-0.6	0.4
Type 2 Diabetes (T2D) (2018)	0.2	0.4	2.0	-0.3	-0.3	-0.4	-1.4	-0.5	0.1	-0.2	-0.9	-1.1	-0.8	-0.2	-0.6	-0.5	-0.7	-0.8	-0.5	-0.1	-0.2	-1.1	-0.1	0.6
Hand grip strength (left)	0.2	0.6	2.8	0.3	0.8	0.6	1.4	0.7	-1.0	0.3	0.4	0.7	0.5	0.9	0.7	1.0	0.8	0.8	0.5	-0.1	0.6	1.7	0.7	-0.3
Frequency of depressed mood in last 2 weeks	0.2	0.3	1.1	0.5	0.5	0.4	0.6	0.5	-0.6	0.5	0.3	-0.7	0.3	0.5	0.5	0.7	0.6	0.4	0.4	0.2	0.7	0.3	1.0	0.4
Ever had hysterectomy (womb removed)	0.2	0.3	1.3	-0.5	-0.3	-0.1	0.4	-0.1	0.6	-0.6	-0.9	-1.1	-0.6	-0.3	0.1	-0.2	0.2	0.2	0.1	-0.4	-0.8	-0.5	-0.8	-0.2
Supplements: Zinc	0.2	0.2	0.7	0.4	0.6	0.2	0.3	0.2	-0.8	0.5	0.6	0.4	0.3	0.6	0.4	0.4	0.4	0.5	0.4	0.5	0.4	0.1	0.4	0.7
Severe depression (siblings)	0.2	0.3	1.4	-0.6	-0.2	-0.4	0.3	-0.4	-0.1	-0.7	-0.0	-0.4	-0.2	-0.1	-0.4	0.1	-0.4	1.0	-0.7	-1.2	-0.2	0.9	0.4	-0.3
Age when periods started (menarche)	0.2	0.4	2.8	-0.4	-0.4	-0.4	0.1	-0.1	0.1	-0.8	-0.5	1.7	0.3	-0.3	-0.4	-0.4	-0.3	0.9	-0.4	-0.9	-0.8	1.0	-0.6	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.2	1.0	0.4	0.7	-0.4	0.7	-0.1	0.8	1.1	0.3	-0.0	0.4	0.7	0.5	0.5	0.8	0.8	0.8	0.6	-0.3	0.8	0.9
Qualifications: CSEs or equivalent	0.2	0.3	1.8	-0.1	0.4	0.5	1.2	0.4	-0.5	-0.1	0.2	-0.9	-0.4	0.4	0.5	0.5	0.7	-0.0	0.4	-0.2	-0.1	1.4	0.4	-0.0
High blood pressure	0.2	0.5	3.5	-0.2	-0.3	-0.1	-1.9	-0.1	0.2	-0.3	-0.0	-0.7	-1.0	-0.1	-0.5	-0.4	-0.6	-0.7	-0.3	-0.3	-0.3	-1.9	-0.2	0.0
Supplements: Glucosamine	0.2	0.2	2.6	-0.0	0.2	-0.1	0.0	-0.4	0.0	0.2	-1.1	-1.6	-0.2	-0.0	0.1	-0.2	0.1	-0.1	0.2	0.3	0.0	-0.6	0.0	0.8
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	1.3	0.2	-0.1	0.1	-0.5	0.4	0.2	-0.3	-0.8	1.0	0.9	-0.2	0.2	-0.2	0.2	1.1	0.1	-0.1	-0.7	0.5	-0.5	-0.2
Alcohol usually taken with meals	0.2	0.4	2.2	0.0	-0.2	-0.3	0.8	-0.5	-0.0	-0.0	0.1	1.4	1.5	-0.2	-0.5	0.1	-0.5	0.7	-0.7	-0.3	0.4	1.0	0.2	0.0
Had other major operations	0.2	0.2	1.0	0.3	0.5	-0.1	-0.1	0.1	-0.4	0.6	0.6	-0.7	0.4	0.4	0.3	0.2	0.2	0.4	0.3	0.7	0.5	-1.0	0.2	0.8
Happiness	0.2	0.2	0.7	0.3	0.5	0.9	-0.0	0.8	-0.5	0.2	0.5	0.7	0.8	0.5	0.6	0.4	0.7	0.3	0.7	0.2	0.0	0.4	0.3	0.1
Illnesses of mother	0.2	0.2	1.5	0.3	-0.5	-0.2	0.1	-0.5	0.5	0.2	-0.9	-1.2	-0.3	-0.4	-0.5	-0.4	-0.5	-0.4	-0.5	0.4	0.1	0.1	-0.5	0.4
Qualifications: O levels/GCSEs or equivalent	0.2	0.2	1.9	0.5	0.1	0.2	0.1	0.2	-0.3	0.5	0.6	1.4	0.9	0.2	0.1	0.4	0.0	-0.0	-0.0	0.4	0.7	0.8	0.4	0.0
Gout (self-reported)	0.2	0.3	1.4	-0.8	-0.1	0.1	-0.1	0.4	0.1	-0.8	-0.1	-0.4	-0.3	0.1	-0.1	-0.4	-0.1	-1.0	-0.1	-0.7	-1.0	0.2	-0.7	-1.2
Hypothyroidism/myxoedema (self-reported)	0.2	0.5	3.4	0.4	-0.5	-0.0	-1.8	-0.6	0.4	0.0	-1.1	-0.6	-0.2	-0.4	-0.7	-0.8	-0.8	0.3	-0.7	0.4	-0.1	-0.8	-0.6	0.7
Birth weight	0.2	0.5	1.8	0.3	0.6	-0.3	1.1	-0.2	-1.1	0.5	0.4	0.8	1.0	0.7	0.1	0.8	0.2	1.0	-0.1	0.0	1.0	1.0	1.3	0.0
Worry too long after embarrassment	0.2	0.3	2.6	-0.3	-0.5	-0.5	-0.1	-0.7	0.7	-0.4	-0.6	-1.6	-0.3	-0.5	-0.5	-0.4	-0.5	-0.4	-0.5	-0.4	-0.4	-0.5	-0.4	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.7	-0.2	0.5	0.4	-0.3	0.4	-0.7	-0.3	0.7	-0.5	-0.2	0.6	0.1	0.3	0.2	0.6	0.1	-0.5	-0.1	-0.8	0.4	0.3
Neck or shoulder pain in last month	0.2	0.3	0.9	0.1	0.5	0.5	0.0	0.5	-0.6	0.3	0.3	-0.9	-0.1	0.6	0.5	0.4	0.4	-1.0	0.5	0.3	0.2	-0.4	0.2	0.9
Pulse rate, automated reading	0.2	0.7	1.8	-1.0	-0.9	-1.2	-0.4	-0.7	0.6	-1.1	-0.6	0.5	-0.1	-0.8	-1.0	-0.9	-1.0	-0.2	-1.1	-1.2	-1.0	-0.5	-0.9	-1.4
Number of full sisters	0.2	0.2	0.4	-0.5	-0.5	-0.6	-0.6	-0.3	0.4	-0.6	-0.3	0.4	-0.0	-0.5	-0.5	-0.4	-0.5	0.3	-0.6	-0.6	-0.5	-0.0	-0.6	-0.6
Age at last live birth	0.2	0.2	1.5	-0.4	-0.5	0.1	-0.2	-0.4	0.2	-0.6	-0.4	0.6	-0.2	-0.4	-0.5	-0.3	-0.4	0.2	-0.6	-0.8	-0.4	-0.0	-0.5	-1.2
Commuting to job workplace: Car/motor vehicle	0.2	0.2	1.0	0.5	0.1	0.1	0.3	-0.1	-0.2	0.7	0.2	-1.0	0.2	0.1	-0.1	0.1	-0.0	-0.7	-0.1	0.9	0.7	-0.2	0.2	0.7
Supplements: Vitamin C	0.2	0.2	1.3	-0.0	0.4	0.6	-0.1	0.3	-0.4	-0.2	1.1	0.8	0.3	0.5	0.3	0.2	0.2	0.5	0.3	-0.2	-0.2	0.6	0.2	0.6
Average weekly red wine intake	0.2	0.2	1.4	-0.2	-0.2	-0.3	0.2	-0.6	0.0	-0.2	-1.0	-1.2	-0.1	-0.1	-0.6	0.1	-0.5	-0.0	-0.6	-0.7	0.4	0.5	0.4	0.3
Handedness (chirality/laterality): Left-handed	0.2	0.3	1.1	0.3	0.6	1.1	0.4	0.6	-0.5	0.3	0.6	0.3	0.3	0.7	0.5	0.7	0.6	0.2	0.7	-0.1	0.5	0.3	0.5	0.1
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.7	-0.3	-0.7	-0.3	-0.5	-0.4	0.5	-0.6	-0.7	-0.4	-0.3	-0.6	-0.7	-0.6	-0.7	0.6	-0.8	-0.6	-0.6	-0.4	-0.6	-0.4
Breast cancer (self-reported)	0.2	0.2	1.0	0.5	0.3	0.5	1.0	0.3	-0.3	0.5	0.9	0.2	0.7	0.3	0.5	0.4	0.4	-0.1	0.4	0.5	0.4	0.6	0.2	0.5
Wears glasses or contact lenses	0.2	0.2	1.0	-0.4	-0.2	-0.3	-1.0	-0.3	0.2	-0.6	-0.6	0.6	-0.1	-0.3	-0.1	-0.5	-0.3	0.3	-0.1	-0.4	-0.7	-0.3	-0.4	0.2
High cholesterol (Self-reported)	0.2	0.4	1.8	0.8	0.6	0.3	-0.4	0.5	-0.6	1.1	0.4	-0.0	-0.1	0.5	0.6	0.3	0.5	0.0	0.7	1.4	0.8	-0.3	0.4	0.6
Alcohol drinker status: Never	0.2	0.3	2.2	-0.6	-0.3	-0.2	0.3	-0.4	0.4	-0.4	-0.5	-1.5	-0.6	-0.3	-0.3	-0.4	-0.3	-1.1	-0.2	-0.4	-0.4	-0.5	-0.5	0.1
Number of operations (self-reported)	0.2	0.2	0.5	0.6	0.3	0.2	0.6	0.4	-0.2	0.6	0.3	0.6	0.6	0.2	0.5	0.4	0.4	0.6	0.5	0.7	0.5	0.5	0.4	0.6
Risk taking	0.2	0.2	1.3	0.3	0.3	0.2	1.1	0.1	-0.4	0.5	0.7	0.8	0.4	0.4	0.3	0.6	0.3	-0.2	0.2	0.3	0.7	0.3	0.6	0.3
Unable to work because of sickness or disability	0.2	0.3	0.9	0.2	-0.6	-0.8	-0.6	-0.9	0.5	0.2	-0.6	-0.3	0.4	-0.6	-0.8	-0.4	-0.9	-0.6	-0.8	0.2	0.4	0.3	0.2	0.5
Heart attack/myocardial infarction (self-reported)	0.2	0.2	1.1	0.3	-0.2	-0.5	-0.7	-0.2	0.4	0.3	-0.8	0.1	1.1	-0.2	-0.1	-0.4	-0.2	-0.2	-0.1	0.8	0.1	-0.2	-0.6	0.5
Neuroticism (Nagel 2018)	0.1	0.3	1.1	0.4	0.4	0.6	0.9	0.8	-0.1	0.2	1.0	-0.9	0.1	0.4	0.5	0.5	0.7	0.2	0.6	0.2	0.2	-0.0	0.4	0.2
Coronary Artery Disease (CAD)	0.1	0.1	0.7	-0.4	0.0	0.1	0.2	0.3	0.1	-0.5	-0.5	0.1	-0.9	0.0	0.1	-0.2	0.1	0.2	0.1	-0.4	-0.6	0.4	-0.0	-0.3
Fasting Glucose	0.1	0.1	0.7	0.2	0.2	0.2	0.1	0.2	-0.1	0.0	-0.7	-0.7	-0.8	0.2	0.1	0.1	0.0	0.2	0.2	-0.0	0.0	0.1	0.1	0.3
HDL Cholesterol	0.1	0.1	0.4	-0.4	-0.1	0.1	0.6	0.1	0.4	-0.5	-0.2	0.0	-0.2	-0.1	0.1	0.0	0.2	0.2	0.0	-0.7	-0.4	0.4	0.1	-0.2
Lupus	0.1	0.2	0.8	-0.4	-0.4	-0.7	0.2	-0.5	0.5	-0.4	-0.6	0.1	0.4	-0.5	-0.3	-0.6	-0.4	-0.0	-0.5	-0.1	-0.6	0.1	-0.9	0.1
Primary Biliary Cirrhosis	0.1	0.2	1.4	0.0	-0.3	-0.3	0.5	-0.1	0.1	-0.0	1.2	1.2	0.3	-0.1	-0.3	-0.1	-0.3	-0.2	-0.4	-0.1	0.1	-0.1	-0.1	-0.0
Blood Eosinophil Count	0.1	0.7	2.7	-0.9	-0.9	-0.4	-0.8	-0.7	1.1	-1.0	-0.1	-0.3	-0.6	-0.9	-0.7	-1.0	-0.8	-1.6	-0.5	-0.9	-1.2	-0.5	-1.2	-0.9
Blood Red Count	0.1	1.1	2.6	-1.5	-1.0	-1.1	-0.3	-0.9	0.9	-1.5	-1.6	-0.3	-1.0	-1.1	-0.9	-1.0	-0.9	-0.5	-1.0	-1.5	-1.4	-0.1	-0.9	-1.3
Blood White Count	0.1	0.7	2.5	1.1	0.8	0.8	-0.4	0.7	-0.8	1.0	1.4	0.3	0.7	0.9	0.5	0.6	0.4	0.1	0.7	1.0	1.0	-0.4	1.0	1.6
Neuroticism	0.1	0.2	0.7	0.4	0.3	0.4	0.7	0.5	-0.2	0.3	0.3	-0.8	0.0	0.4	0.3	0.4	0.3	0.6	0.3	0.2	0.3	0.3	0.4	0.3
Chronotype (morning person)	0.1	0.3	1.3	-0.4	-0.4	-0.7	-0.0	-0.9	0.4	-0.3	0.6	-0.7	0.3	-0.4	-0.6	-0.4	-0.7	-0.9	-0.6	-0.4	-0.1	-1.2	0.1	-0.2
Tanning	0.1	1.4	4.1	1.1	1.1	1.3	2.0	1.0	-1.0	1.0	0.7	0.8	1.4	1.0	1.2	1.0	1.3	1.3	1.2	1.0	0.9	1.7	0.9	1.2
Medication for hormone replacement therapy	0.1	0.2	1.3	-0.2	-0.1	-0.3	-0.7	-0.3	0.4	-0.2	-1.1	-0.6	-0.4	-0.1	-0.1	-0.0	-0.2	0.5	-0.2	-0.5	-0.1	0.3	0.1	0.1
Townsend deprivation index at recruitment	0.1	0.2	2.1	-0.2	-0.1	-0.0	-0.4	-0.0	-0.0	-0.5	0.9	1.4	0.3	-0.1	-0.1	-0.3	-0.1	0.6	-0.1	-0.4	-0.6	0.1	-0.4	0.0
Nervous feelings	0.1	0.3	1.7	0.4	0.6	0.6	-0.3	0.5	-0.2	0.4	0.8	-0.5	0.0	0.6	0.4	0.4	0.3	0.3	0.6	0.3	0.5	-0.4	0.4	1.3
Hearing difficulty/problems with background noise	0.1	0.1	0.6	-0.3	-0.2	0.2	0.8	0.1	0.5	-0.4	0.5	-0.5	-0.1	-0.2	0.1	-0.1	0.1	-0.5	0.1	-0.3	-0.6	-0.2	-0.4	-0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	1.0	0.7	0.5	0.5	-0.3	0.6	-0.4	0.6	0.6	-0.6	-0.3	0.5	0.7	0.6	0.5	0.4	0.7	0.5	0.6	-0.2	1.0	0.8
Diabetes (self-reported)	0.1	0.1	0.8	0.0	0.2	-0.1	-0.7	-0.0	-0.5	0.1	-0.4	-0.5	-0.1	0.3	-0.2	0.0	-0.2	-0.2	-0.1	0.1	0.2	-0.7	0.3	0.9
Medication: Simvastatin	0.1	0.2	0.7	0.3	0.2	-0.0	-0.9	0.0	-0.4	0.5	0.5	-0.1	-0.2	0.3	-0.0	-0.0	-0.2	-0.5	0.2	0.7	0.4	-0.9	0.1	0.6
Neuroticism score	0.1	0.2	0.4	0.4	0.3	0.5	0.5	0.6	-0.1	0.3	0.6	-0.6	0.2	0.4	0.5	0.5	0.5	0.4	0.4	0.2	0.2	0.2	0.3	0.2
Worrier / anxious feelings	0.1	0.1	0.5	0.1	0.0	0.3	0.7	0.6	-0.0	-0.0	0.7	-0.1	0.1	0.1	0.2	0.3	0.3	0.1	0.1	-0.2	0.0	0.4	-0.1	-0.6
Noisy workplace	0.1	0.2	0.7	0.3	-0.2	-0.5	0.8	-0.5	0.1	0.2	0.0	0.6	0.4	-0.2	-0.3	-0.1	-0.3	0.8	-0.4	0.3	0.3	0.8	0.3	0.4
Mouth/teeth dental problems: Dentures	0.1	0.2	2.6	-0.1	-0.2	-0.7	-0.7	-0.1	0.2	-0.1	0.2	-0.2	-0.0	-0.2	-0.1	-0.6	-0.2	-0.4	-0.1	0.4	-0.5	-1.6	-0.6	0.4
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.5	-0.2	0.1	0.0	0.3	-0.1	-0.1	-0.0	0.4	-0.7	-0.4	0.2	-0.2	0.2	-0.2	-0.4	-0.2	-0.3	0.3	0.3	0.5	0.2
Medication: Cholesterol lowering	0.1	0.2	2.4	0.0	-0.3	-0.4	-1.5	-0.0	0.1	0.0	-0.6	0.2	-0.2	-0.2	-0.4	-0.3	-0.4	-0.4	-0.3	0.2	-0.1	-0.9	-0.3	-0.5
Depression (self-reported)	0.1	0.1	0.4	-0.5	0.0	0.5	0.2	0.4	0.0	-0.4	0.1	-0.4	-0.1	0.1	0.1	0.1	0.2	-0.3	0.1	-0.6	-0.2	0.2	0.1	-0.3
Medication: Lansoprazole	0.1	0.1	0.7	0.2	-0.0	-0.2	-0.2	-0.2	0.1	0.0	-0.1	-0.8	-0.6	0.0	-0.0	-0.1	-0.2	0.7	-0.1	0.2	-0.0	-0.2	-0.1	0.8
Pulse wave Arterial Stiffness index	0.1	0.1	0.4	-0.3	0.1	-0.5	-0.3	-0.0	-0.4	-0.2	-0.3	0.3	0.2	0.0	0.2	0.3	0.2	0.6	-0.1	-0.4	-0.0	-0.4	0.3	-0.7
Medication for cholesterol, blood pressure or diabetes	0.1	0.1	0.8	0.4	0.2	0.4	0.9	-0.1	0.1	0.3	0.4	-0.3	0.1	0.1	0.3	0.1	0.3	0.2	0.4	0.4	0.2	0.5	-0.0	0.7
Leg fat percentage (right)	0.1	0.4	2.0	0.3	0.2	0.6	-1.3	0.9	-0.0	0.1	0.2	-1.3	-0.8	0.3	0.3	-0.0	0.4	-0.2	0.5	0.3	-0.3	-1.4	-0.4	0.3
Comparative body size at age 10	0.1	0.2	2.3	0.5	-0.1	0.4	0.5	-0.1	0.2	0.2	0.2	-1.5	-0.5	0.1	-0.2	-0.2	-0.2	-0.2	0.0	0.3	0.2	-0.1	0.3	0.4
Age at first live birth	0.1	0.2	0.6	0.5	0.5	0.7	-0.0	0.4	-0.8	0.5	0.5	0.6	0.1	0.7	0.2	0.6	0.3	0.4	0.1	0.3	0.7	-0.0	0.4	0.3
Pulse wave peak to peak time	0.1	0.1	0.6	-0.1	-0.3	0.2	0.2	-0.3	0.6	-0.1	-0.2	-0.5	-0.5	-0.3	-0.4	-0.5	-0.4	-0.7	-0.2	-0.0	-0.2	0.4	-0.5	0.3
Qualifications: College or University degree	0.1	0.4	2.1	0.0	0.2	0.0	1.0	-0.2	-0.5	0.1	0.1	1.4	1.5	0.2	-0.0	0.4	-0.0	0.7	-0.1	-0.3	0.5	1.2	0.5	-0.2
Medication: Ibuprofen	0.1	0.1	0.6	0.1	0.2	0.0	0.1	-0.2	-0.1	0.3	0.8	-0.6	-0.6	0.3	-0.1	0.3	-0.1	-0.1	-0.0	-0.0	0.6	-0.0	0.7	0.6
Heart disease (mother)	0.1	0.1	0.4	-0.3	-0.2	-0.5	-0.5	-0.4	0.2	-0.1	-0.3	-0.5	0.2	-0.4	-0.2	-0.1	-0.3	-0.1	-0.2	-0.3	0.1	-0.7	-0.1	-0.5
Overall health rating	0.1	0.2	0.9	0.1	-0.4	-0.5	-0.5	-0.3	0.4	0.1	-0.2	-1.0	0.1	-0.3	-0.6	-0.6	-0.7	-0.6	-0.4	0.3	0.0	-0.9	-0.2	0.1
Had major operations	0.1	0.1	0.9	-0.1	-0.4	-0.1	0.1	-0.2	0.6	-0.3	0.2	0.9	-0.2	-0.3	-0.1	-0.4	-0.1	-0.3	0.0	-0.2	-0.6	0.1	-0.6	-0.1
Leg pain on walking	0.1	0.2	0.8	0.3	-0.1	-0.6	0.3	-0.3	-0.0	0.3	-0.0	0.6	0.9	-0.1	-0.4	-0.1	-0.5	0.8	-0.4	0.2	0.5	0.5	0.3	0.3
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.8	0.3	0.2	0.3	0.5	0.4	-0.2	0.1	0.2	0.3	0.2	0.3	0.2	0.4	0.2	0.9	0.1	-0.0	0.2	0.7	0.4	0.5
Hypertension (Self-reported)	0.1	0.3	2.5	0.2	0.3	0.4	-1.6	0.4	-0.5	0.2	0.6	-0.2	-0.6	0.5	0.1	0.2	-0.0	-0.4	0.2	0.1	0.3	-1.5	0.5	0.3
Mineral and other dietary supplements	0.1	0.1	1.0	-0.1	-0.4	0.1	-0.3	0.1	0.3	-0.4	-0.0	0.3	-0.0	-0.4	-0.2	-0.2	-0.2	-0.3	-0.3	-0.3	-0.4	0.2	-0.5	-1.0
Hearing aid user	0.1	0.1	1.6	0.0	-0.3	-0.4	-0.4	-0.2	0.2	-0.1	0.2	1.3	0.5	-0.3	-0.3	-0.2	-0.3	0.5	-0.3	-0.1	-0.1	-0.0	-0.2	-0.3
Mother’s age at death	0.1	0.1	0.3	-0.6	0.1	0.2	-0.1	0.4	0.1	-0.4	0.1	0.1	-0.5	0.2	0.3	0.2	0.3	-0.6	0.2	-0.5	-0.4	-0.0	0.1	-0.5
Commuting to job workplace: Public transport	0.1	0.1	0.6	-0.4	-0.1	-0.0	-0.2	0.0	0.1	-0.6	-0.3	0.8	-0.0	-0.0	-0.3	-0.5	-0.3	0.2	-0.2	-0.5	-0.7	0.2	-0.4	-0.6
Eye problems/disorders: Glaucoma	0.1	0.1	0.4	0.3	0.3	0.2	-0.1	0.3	-0.2	0.5	0.6	0.1	0.2	0.2	0.3	0.4	0.2	-0.1	0.4	0.4	0.6	-0.1	0.6	0.4
Medication: Atorvastatin	0.1	0.1	0.4	0.1	-0.2	-0.1	-0.3	0.2	0.4	-0.0	-0.3	-0.6	-0.4	-0.2	0.0	-0.2	0.0	-0.5	0.1	0.2	-0.2	-0.5	-0.3	-0.3
Leg fat percentage (left)	0.1	0.5	2.7	-0.1	-0.2	0.2	-1.5	0.4	0.3	-0.3	-0.3	-1.6	-1.2	-0.1	-0.1	-0.4	-0.1	-0.5	0.0	-0.0	-0.6	-1.6	-0.8	0.1
Average weekly beer plus cider intake	0.1	0.1	1.7	-0.1	-0.1	-0.4	-0.4	-0.3	0.1	0.0	0.8	0.1	-0.2	-0.2	0.0	-0.3	-0.0	-0.2	0.1	0.2	-0.2	-1.3	-0.2	0.3
Ever had prostate specific antigen (PSA) test	0.1	0.2	0.5	-0.6	-0.3	0.0	-0.2	0.1	0.4	-0.5	-0.6	-0.2	-0.2	-0.3	-0.1	-0.3	-0.1	-0.3	-0.2	-0.4	-0.7	-0.4	-0.6	-0.7
Pack years of smoking	0.1	0.2	1.3	-0.5	-0.2	-0.2	-0.3	-0.2	0.4	-0.2	-0.4	-0.6	0.0	-0.3	-0.3	-0.5	-0.4	-1.1	-0.1	-0.2	-0.3	-0.5	-0.0	0.0
Alzheimer’s Disease (including proxy)	0.0	0.1	0.5	-0.2	-0.1	-0.2	0.7	-0.5	0.4	-0.2	-0.2	-0.0	-0.1	-0.2	0.1	0.0	0.0	0.0	0.1	-0.5	-0.1	0.4	-0.1	0.0
Waist Hip Ratio (WHR)	0.0	0.2	0.6	0.5	0.5	-0.0	-0.3	0.0	-0.6	0.7	0.2	-0.4	0.5	0.4	0.1	0.2	0.1	0.1	0.2	0.8	0.7	-0.4	0.2	0.6
Hair Pigment	0.0	0.7	2.8	-0.9	-0.6	-1.3	-1.7	-1.1	-0.0	-0.8	-0.5	-0.3	-0.4	-0.5	-1.2	-0.7	-1.3	-0.6	-1.3	-0.8	-0.4	-0.6	-0.1	-0.7
Medication: Blood pressure	0.0	0.1	0.4	-0.1	0.1	-0.1	-0.6	0.2	-0.4	-0.1	-0.1	0.6	0.1	0.3	-0.1	0.2	-0.1	0.1	-0.2	-0.3	0.2	-0.1	0.6	-0.4
Supplements: Fish oil (including cod liver oil)	0.0	0.1	0.3	0.0	0.2	-0.2	0.4	-0.2	-0.0	0.2	-0.4	0.4	0.2	0.1	0.1	0.0	0.2	0.3	0.2	0.2	0.2	0.6	0.1	0.4
Medication: Bendroflumethiazide	0.0	0.1	0.5	-0.1	0.2	0.1	-0.7	0.2	-0.1	-0.0	-0.5	0.0	-0.3	0.1	0.1	-0.2	-0.0	-0.5	0.3	0.2	-0.3	-0.3	-0.2	0.3

Hub : Genes

C5orf63

Models

Trait associations