[Hub]/) : Traits : Leg predicted mass (left) :

chr11:64,407,419-66,333,072

Best TWAS P=4.85e-09 · Best GWAS P=3.7e-09 conditioned to 0.000308

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FIBP 0.08 0.11 enet 20 0.12 8.1e-14 3.7 5.2 2.2e-07 -0.47 0.98 0.01 FALSE
2 GTEx Adrenal Gland CTSW 0.13 0.08 lasso 12 0.06 3.0e-03 5.1 -5.1 2.9e-07 0.26 0.26 0.29 FALSE
3 GTEx Brain Cerebellar Hemisphere EFEMP2 0.35 0.15 enet 5 0.09 2.2e-03 5.4 5.7 9.8e-09 -0.33 0.05 0.87 FALSE
4 GTEx Brain Cerebellum EFEMP2 0.45 0.40 enet 8 0.39 1.6e-12 5.1 5.4 5.1e-08 -0.31 0.07 0.93 FALSE
5 GTEx Cells Transformed fibroblasts EFEMP2 0.06 0.06 lasso 3 0.07 7.8e-06 5.5 5.7 1.4e-08 -0.27 0.07 0.92 FALSE
6 GTEx Colon Transverse DPF2 0.19 0.01 lasso 4 0.05 1.6e-03 3.3 5.4 5.9e-08 -0.07 0.08 0.11 TRUE
7 The Cancer Genome Atlas Breast Invasive Carcinoma EFEMP2 0.04 0.02 lasso 5 0.02 1.4e-05 5.6 5.5 4.1e-08 -0.35 0.02 0.97 FALSE
8 The Cancer Genome Atlas Glioblastoma Multiforme CTSW 0.16 0.18 enet 16 0.19 2.3e-06 5.1 -5.9 4.8e-09 0.37 0.08 0.83 TRUE
9 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DKFZp761E198 0.07 0.02 blup 39 0.03 5.9e-04 -4.7 -5.5 4.8e-08 0.55 0.02 0.62 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DPF2 0.07 0.04 blup 28 0.04 2.9e-05 -5.0 5.1 3.0e-07 -0.12 0.00 0.97 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma DPF2 0.03 0.02 blup 28 0.02 1.2e-03 -5.0 5.3 1.5e-07 -0.12 0.00 0.90 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma EFEMP2 0.01 0.00 blup 45 0.01 3.0e-02 2.5 5.2 2.3e-07 -0.37 0.03 0.20 FALSE
13 The Cancer Genome Atlas Lung Adenocarcinoma FIBP 0.02 0.01 blup 45 0.02 1.3e-03 3.9 5.3 1.2e-07 -0.43 0.06 0.48 FALSE
14 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CAPN1 0.03 0.02 blup 39 0.02 2.1e-03 -4.8 -5.2 2.5e-07 0.18 0.00 0.92 FALSE
15 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma POLA2 0.12 0.03 enet 9 0.05 2.5e-04 -5.0 5.2 1.9e-07 -0.16 0.01 0.67 FALSE
16 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CTSW 0.16 0.10 enet 24 0.15 1.9e-06 3.7 -5.1 2.9e-07 0.31 0.52 0.27 FALSE
17 The Cancer Genome Atlas Soft Tissue Sarcoma SNX32 0.08 0.08 lasso 2 0.10 1.5e-06 5.5 5.3 9.3e-08 -0.29 0.05 0.94 FALSE