[Hub]/) : Traits : Leg predicted mass (left) : ← →

chr11:46,499,874-48,285,906

Best TWAS P=1.64e-12 · Best GWAS P=7.39e-13 conditioned to 0.00255

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta MADD 0.09 0.03 enet 22 0.04 1.9e-03 -7.2 7.1 1.6e-12 -0.72 0.01 0.93 TRUE
2 GTEx Artery Aorta PACSIN3 0.10 0.04 lasso 4 0.03 1.1e-02 4.2 5.6 2.7e-08 -0.27 0.36 0.06 FALSE
3 GTEx Artery Tibial MADD 0.09 0.00 enet 13 0.02 1.1e-02 -2.8 5.6 2.3e-08 -0.63 0.17 0.64 FALSE
4 GTEx Esophagus Mucosa MADD 0.27 0.04 enet 18 0.12 4.1e-08 -3.2 5.7 9.7e-09 -0.54 0.15 0.46 FALSE
5 GTEx Esophagus Muscularis MADD 0.13 0.07 enet 8 0.11 2.0e-07 -3.3 5.7 1.2e-08 -0.62 0.45 0.40 FALSE
6 GTEx Prostate PSMC3 0.21 0.10 lasso 6 0.20 7.9e-06 4.9 -5.1 2.8e-07 0.12 0.14 0.13 FALSE
7 NTR Blood MADD 0.01 0.01 enet 8 0.01 4.7e-03 5.2 6.7 1.7e-11 -0.40 0.16 0.10 FALSE
8 ROSMAP Brain Pre-frontal Cortex MADD 0.33 0.16 enet 23 0.23 1.9e-29 -3.3 5.3 9.3e-08 -0.46 1.00 0.00 FALSE
9 ROSMAP Brain Pre-frontal Cortex CELF1 0.03 0.01 bslmm 289 0.01 2.9e-02 5.1 5.6 1.7e-08 -0.39 0.16 0.13 FALSE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma MADD 0.16 0.05 blup 64 0.08 2.2e-09 4.9 5.5 4.5e-08 -0.31 0.01 0.99 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma MADD 0.15 0.04 enet 10 0.06 4.5e-07 -3.3 5.3 9.2e-08 -0.36 0.13 0.21 FALSE