[Hub]/) : Traits : Leg predicted mass (left) : ← →

chr3:153,142,317-154,733,231

Best TWAS P=2.86e-12 · Best GWAS P=1.87e-11 conditioned to 0.0315

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DHX36 0.05 0.06 blup 357 0.05 1.3e-06 -6.1 -6.3 3.2e-10 0.66 0.22 0.78 FALSE
2 GTEx Adipose Subcutaneous ARHGEF26 0.10 0.06 enet 8 0.07 2.2e-06 -6.1 6.2 6.0e-10 -0.61 0.17 0.83 FALSE
3 GTEx Artery Tibial ARHGEF26 0.11 0.12 enet 12 0.12 5.9e-10 -6.1 5.6 1.7e-08 -0.54 0.23 0.77 FALSE
4 GTEx Ovary ARHGEF26 0.14 0.03 enet 15 0.06 1.4e-02 6.5 7.0 2.9e-12 -0.76 0.04 0.68 TRUE
5 GTEx Pancreas ARHGEF26 0.26 0.26 lasso 5 0.28 3.2e-12 -6.0 7.0 3.1e-12 -0.73 0.18 0.82 FALSE
6 GTEx Skin Not Sun Exposed Suprapubic ARHGEF26 0.13 0.11 lasso 4 0.07 6.8e-05 -6.0 6.6 4.3e-11 -0.70 0.17 0.82 FALSE
7 GTEx Skin Sun Exposed Lower leg ARHGEF26 0.10 0.08 enet 12 0.11 2.9e-09 -6.1 5.9 4.1e-09 -0.50 0.24 0.76 FALSE
8 GTEx Spleen DHX36 0.39 0.09 enet 21 0.34 2.1e-09 -3.2 -5.2 2.2e-07 0.66 0.38 0.58 FALSE
9 GTEx Thyroid ARHGEF26 0.09 0.07 enet 17 0.08 1.9e-06 -6.1 6.2 5.6e-10 -0.62 0.19 0.80 FALSE
10 GTEx Thyroid DHX36 0.06 0.01 lasso 4 0.02 1.7e-02 -5.5 -5.3 1.4e-07 0.49 0.23 0.41 FALSE
11 METSIM Adipose ARHGEF26 0.07 0.08 lasso 6 0.07 3.5e-11 -6.1 6.2 6.8e-10 -0.55 0.22 0.78 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SGEF 0.04 0.04 enet 12 0.04 1.1e-05 -5.9 6.8 1.2e-11 -0.77 0.07 0.90 FALSE
13 The Cancer Genome Atlas Brain Lower Grade Glioma DHX36 0.11 0.09 enet 11 0.10 6.4e-12 -5.3 -5.6 2.5e-08 0.48 0.86 0.14 FALSE