Best TWAS P=3.79e-14 · Best GWAS P=1.77e-17 conditioned to 4.29e-10
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | FNDC3B | 0.07 | 0.06 | enet | 8 | 0.05 | 3.2e-07 | -8.0 | 7.6 | 3.8e-14 | 0.04 | 0.15 | 0.84 | TRUE |
2 | YFS | Blood | TNFSF10 | 0.09 | 0.04 | bslmm | 462 | 0.08 | 1.6e-24 | 6.0 | 6.5 | 9.6e-11 | 0.38 | 1.00 | 0.00 | TRUE |
3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | FNDC3B | 0.07 | 0.02 | enet | 6 | 0.02 | 3.9e-03 | 5.5 | -5.9 | 3.4e-09 | -0.83 | 0.01 | 0.98 | FALSE |