Best TWAS P=1.29e-11 · Best GWAS P=5.07e-11 conditioned to 0.175
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FARP1 | 0.10 | 0.05 | enet | 5 | 0.05 | 1.4e-06 | -6.3 | 6.2 | 5.7e-10 | -0.94 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Adipose Subcutaneous | STK24 | 0.18 | 0.06 | lasso | 8 | 0.08 | 2.4e-07 | -5.0 | -5.9 | 4.2e-09 | 0.75 | 0.04 | 0.96 | FALSE |
| 3 | GTEx | Artery Tibial | STK24 | 0.12 | 0.10 | lasso | 3 | 0.08 | 8.4e-07 | -6.2 | -6.0 | 1.5e-09 | 0.85 | 0.04 | 0.96 | FALSE |
| 4 | GTEx | Esophagus Mucosa | FARP1-AS1 | 0.11 | 0.03 | lasso | 2 | 0.04 | 1.7e-03 | -6.3 | -6.4 | 1.7e-10 | 0.99 | 0.01 | 0.98 | FALSE |
| 5 | NTR | Blood | FARP1 | 0.02 | 0.01 | lasso | 3 | 0.01 | 4.3e-04 | -6.3 | -6.8 | 1.3e-11 | 0.87 | 0.02 | 0.98 | TRUE |
| 6 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | STK24 | 0.04 | 0.03 | lasso | 6 | 0.04 | 5.3e-05 | 5.5 | 5.3 | 9.0e-08 | -0.48 | 0.68 | 0.14 | FALSE |