[Hub]/) : Traits : Arm fat percentage (right) :

chr17:39,993,748-41,538,783

Best TWAS P=2.9e-11 · Best GWAS P=1.14e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous TUBG2 0.21 0.18 enet 17 0.26 2.1e-21 -4.0 -5.4 6.6e-08 -0.75 0.92 0.08 FALSE
2 GTEx Artery Tibial HSD17B1 0.12 0.07 lasso 9 0.07 4.4e-06 -5.0 -5.2 1.7e-07 -0.60 0.30 0.69 FALSE
3 GTEx Artery Tibial RP11-400F19.6 0.07 0.01 lasso 5 0.01 3.0e-02 6.8 -6.6 3.0e-11 -0.97 0.00 0.99 FALSE
4 GTEx Brain Caudate basal ganglia TUBG2 0.39 0.24 enet 45 0.25 7.7e-08 -5.0 -6.0 1.9e-09 -0.67 0.12 0.87 FALSE
5 GTEx Cells Transformed fibroblasts TUBG2 0.16 0.18 lasso 4 0.17 6.5e-13 -5.0 -5.2 2.0e-07 -0.66 0.99 0.01 FALSE
6 GTEx Cells Transformed fibroblasts CNTNAP1 0.07 0.08 lasso 5 0.06 1.9e-05 5.0 5.3 1.4e-07 0.73 0.12 0.73 FALSE
7 GTEx Cells Transformed fibroblasts CTD-3193K9.3 0.07 0.08 lasso 3 0.07 1.2e-05 5.0 5.1 2.8e-07 0.71 0.18 0.74 FALSE
8 GTEx Esophagus Mucosa TUBG2 0.09 0.09 lasso 4 0.11 5.5e-08 -5.0 -6.4 1.6e-10 -0.84 0.02 0.98 FALSE
9 GTEx Esophagus Muscularis TUBG2 0.14 0.16 enet 17 0.06 2.1e-04 -5.0 -5.2 1.8e-07 -0.66 0.96 0.04 FALSE
10 GTEx Esophagus Muscularis NAGLU 0.29 0.09 lasso 5 0.07 6.2e-05 5.5 -5.5 4.1e-08 -0.82 0.28 0.62 FALSE
11 GTEx Esophagus Muscularis RP11-400F19.8 0.17 0.05 lasso 4 0.02 3.9e-02 5.5 -5.8 8.6e-09 -0.70 0.04 0.43 FALSE
12 GTEx Lung TUBG2 0.08 0.02 enet 8 0.04 7.8e-04 -5.0 -5.3 9.5e-08 -0.74 0.08 0.76 FALSE
13 GTEx Muscle Skeletal TUBG2 0.12 0.09 lasso 8 0.10 1.1e-09 5.7 -5.4 8.2e-08 -0.91 0.00 1.00 FALSE
14 GTEx Nerve Tibial RP11-400F19.8 0.10 0.03 lasso 3 0.02 8.2e-03 5.5 -5.3 1.4e-07 -0.83 0.14 0.25 FALSE
15 GTEx Pancreas CNTNAP1 0.13 0.09 lasso 7 0.09 9.1e-05 5.3 5.7 9.4e-09 0.82 0.16 0.60 FALSE
16 GTEx Pancreas FAM134C 0.08 0.04 enet 9 0.03 2.0e-02 4.1 5.2 2.3e-07 0.80 0.10 0.62 FALSE
17 GTEx Pancreas CTD-3193K9.3 0.12 0.07 lasso 5 0.07 5.7e-04 5.3 5.7 1.1e-08 0.83 0.13 0.50 FALSE
18 GTEx Skin Not Sun Exposed Suprapubic TUBG2 0.15 0.13 lasso 5 0.12 4.0e-07 6.8 -6.7 2.9e-11 -0.99 0.00 1.00 TRUE
19 GTEx Skin Sun Exposed Lower leg TUBG2 0.14 0.10 enet 25 0.12 4.9e-10 -4.9 -5.9 4.3e-09 -0.83 0.01 0.99 FALSE
20 GTEx Stomach HSD17B1P1 0.10 0.04 lasso 3 0.04 6.9e-03 5.0 -5.9 2.8e-09 -0.76 0.09 0.38 FALSE
21 GTEx Thyroid HSD17B1P1 0.04 0.00 enet 9 0.00 2.2e-01 -5.0 -6.0 1.8e-09 -0.74 0.06 0.75 FALSE
22 METSIM Adipose TUBG2 0.08 0.09 lasso 6 0.09 5.2e-13 4.1 -5.2 2.0e-07 -0.79 0.97 0.03 FALSE
23 The Cancer Genome Atlas Breast Invasive Carcinoma TUBG2 0.02 0.01 lasso 2 0.01 1.7e-02 5.7 -5.7 1.3e-08 -0.86 0.00 0.80 FALSE
24 The Cancer Genome Atlas Brain Lower Grade Glioma HSD17B1 0.30 0.05 enet 14 0.06 2.8e-07 -4.2 -5.6 2.4e-08 -0.71 0.44 0.53 FALSE
25 The Cancer Genome Atlas Lung Adenocarcinoma TUBG2 0.07 0.01 enet 7 0.02 2.2e-03 5.7 -5.6 1.7e-08 -0.80 0.00 0.89 FALSE
26 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PSMC3IP 0.02 0.02 blup 33 0.02 9.8e-04 -5.0 -6.0 1.9e-09 -0.78 0.03 0.76 FALSE
27 The Cancer Genome Atlas Prostate Adenocarcinoma TUBG2 0.04 0.02 blup 29 0.02 1.5e-03 -4.9 -5.6 2.4e-08 -0.70 0.02 0.69 FALSE
28 The Cancer Genome Atlas Thyroid Carcinoma HSD17B1 0.05 0.07 blup 29 0.07 2.3e-07 -4.0 -5.5 3.7e-08 -0.76 0.66 0.33 FALSE
29 The Cancer Genome Atlas Thyroid Carcinoma TUBG2 0.20 0.13 blup 29 0.17 1.7e-16 5.7 -5.7 1.3e-08 -0.84 0.00 1.00 FALSE