Best TWAS P=2.25e-09 · Best GWAS P=7.95e-13 conditioned to 0.000901
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ADARB1 | 0.12 | 0.03 | blup | 656 | 0.03 | 0.00036 | -4.7 | -6.0 | 2.2e-09 | 0.51 | 0.30 | 0.66 | TRUE |
| 2 | GTEx | Muscle Skeletal | PTTG1IP | 0.07 | 0.01 | enet | 6 | 0.00 | 0.09740 | -6.3 | 5.3 | 1.3e-07 | -0.71 | 0.01 | 0.88 | FALSE |
| 3 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | C21orf122 | 0.20 | 0.04 | lasso | 6 | 0.08 | 0.00026 | 5.5 | -5.2 | 2.0e-07 | 0.57 | 0.00 | 0.97 | TRUE |