[Hub]/) : Traits : Arm fat percentage (right) :

chr22:37,528,576-39,663,066

Best TWAS P=1.52e-13 · Best GWAS P=1.38e-11 conditioned to 0.0486

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous BAIAP2L2 0.11 0.03 lasso 5 0.04 1.8e-04 5.3 -6.2 4.9e-10 -0.71 0.02 0.90 FALSE
2 GTEx Adipose Subcutaneous TMEM184B 0.08 0.08 lasso 4 0.07 1.0e-06 4.4 -5.2 2.1e-07 -0.59 0.82 0.14 FALSE
3 GTEx Artery Aorta C22orf23 0.10 0.01 enet 24 0.02 1.6e-02 3.1 5.8 6.6e-09 0.34 0.26 0.08 FALSE
4 GTEx Artery Aorta PLA2G6 0.10 0.02 enet 9 0.02 4.5e-02 4.2 6.8 1.1e-11 0.68 0.09 0.53 FALSE
5 GTEx Artery Aorta TMEM184B 0.17 0.07 enet 34 0.03 1.2e-02 5.9 -6.6 3.3e-11 -0.68 0.06 0.73 FALSE
6 GTEx Artery Aorta AL021977.1 0.13 0.00 enet 17 0.01 8.7e-02 6.4 -7.4 1.5e-13 -0.73 0.04 0.71 TRUE
7 GTEx Brain Cortex TMEM184B 0.29 0.12 lasso 7 0.09 1.6e-03 5.9 -6.3 3.7e-10 -0.91 0.01 0.88 FALSE
8 GTEx Cells EBV-transformed lymphocytes PLA2G6 0.28 0.17 enet 13 0.18 1.3e-06 -5.6 6.0 2.2e-09 0.69 0.31 0.51 FALSE
9 GTEx Cells Transformed fibroblasts ANKRD54 0.11 0.09 lasso 4 0.09 5.3e-07 -5.5 -5.8 8.7e-09 -0.19 0.76 0.09 FALSE
10 GTEx Cells Transformed fibroblasts PLA2G6 0.23 0.09 lasso 9 0.10 9.9e-08 5.3 6.0 2.4e-09 0.81 0.64 0.36 FALSE
11 GTEx Esophagus Gastroesophageal Junction PLA2G6 0.28 0.24 lasso 5 0.23 1.1e-08 -5.6 6.0 2.5e-09 0.64 0.66 0.23 FALSE
12 GTEx Esophagus Mucosa PLA2G6 0.22 0.02 lasso 6 0.04 1.9e-03 5.3 6.0 2.1e-09 0.77 0.10 0.88 FALSE
13 GTEx Esophagus Muscularis PLA2G6 0.12 0.00 enet 18 0.01 1.4e-01 5.3 5.8 8.8e-09 0.62 0.09 0.27 FALSE
14 GTEx Esophagus Muscularis TMEM184B 0.11 0.01 enet 10 0.06 2.7e-04 3.0 -5.4 5.1e-08 -0.60 0.27 0.19 FALSE
15 GTEx Muscle Skeletal ANKRD54 0.15 0.02 enet 21 0.04 1.1e-04 -5.5 -5.4 7.8e-08 -0.15 0.83 0.06 FALSE
16 GTEx Muscle Skeletal DMC1 0.13 0.01 enet 17 0.04 3.3e-05 5.3 5.6 1.6e-08 0.59 0.05 0.73 FALSE
17 GTEx Nerve Tibial PLA2G6 0.34 0.08 lasso 8 0.11 2.9e-08 -5.6 6.0 2.2e-09 0.72 0.68 0.32 FALSE
18 GTEx Nerve Tibial MAFF 0.14 0.06 lasso 3 0.05 1.2e-04 6.7 -6.5 6.1e-11 -0.98 0.01 0.99 FALSE
19 GTEx Nerve Tibial AL021977.1 0.16 0.05 lasso 3 0.07 9.3e-06 4.3 -5.2 2.1e-07 -0.62 0.44 0.53 FALSE
20 GTEx Skin Sun Exposed Lower leg ANKRD54 0.07 0.04 enet 17 0.04 1.6e-04 -5.5 -5.5 4.6e-08 -0.22 0.45 0.09 FALSE
21 GTEx Skin Sun Exposed Lower leg BAIAP2L2 0.09 0.09 lasso 4 0.09 5.5e-08 5.1 -5.4 6.1e-08 -0.74 0.36 0.64 FALSE
22 GTEx Thyroid PLA2G6 0.34 0.20 lasso 5 0.18 4.5e-14 -5.6 5.9 2.7e-09 0.67 0.83 0.17 FALSE
23 GTEx Thyroid TMEM184B 0.19 0.16 lasso 7 0.18 1.0e-13 4.4 -5.7 1.3e-08 -0.67 0.99 0.01 FALSE
24 GTEx Thyroid AL021977.1 0.20 0.11 lasso 6 0.12 2.7e-09 4.3 -5.8 6.7e-09 -0.66 0.96 0.04 FALSE
25 ROSMAP Brain Pre-frontal Cortex ANKRD54 0.03 0.00 blup 397 0.01 2.2e-02 2.2 -5.5 3.0e-08 -0.28 0.18 0.06 FALSE
26 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ANKRD54 0.20 0.06 lasso 1 0.06 3.0e-07 -5.5 -5.5 3.8e-08 -0.17 0.00 1.00 FALSE
27 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PLA2G6 0.05 0.01 blup 76 0.01 7.7e-02 6.8 6.8 1.3e-11 0.83 0.01 0.85 FALSE
28 The Cancer Genome Atlas Thyroid Carcinoma PLA2G6 0.03 0.02 lasso 2 0.03 6.5e-04 5.8 5.9 4.9e-09 0.81 0.08 0.27 FALSE