Best TWAS P=7.43e-08 · Best GWAS P=1.11e-06 conditioned to 0.024
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | ACO2 | 0.06 | 0.02 | enet | 15 | 0.06 | 1.2e-05 | 4.4 | 5.1 | 3.0e-07 | -0.60 | 0.06 | 0.90 | FALSE |
| 2 | GTEx | Breast Mammary Tissue (Male) | CYP2D7P1 | 0.32 | 0.00 | lasso | 8 | 0.02 | 9.7e-02 | 3.5 | -5.4 | 7.4e-08 | 0.29 | 0.01 | 0.02 | TRUE |
| 3 | GTEx | Nerve Tibial | ACO2 | 0.06 | 0.05 | lasso | 5 | 0.04 | 8.5e-04 | 4.6 | 5.2 | 1.5e-07 | -0.48 | 0.05 | 0.92 | TRUE |