Best TWAS P=1.13e-08 · Best GWAS P=5.67e-08 conditioned to 0.0269
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Breast Mammary Tissue | BCS1L | 0.05 | 0.03 | enet | 7 | 0.03 | 0.00681 | -4.1 | -5.4 | 8.1e-08 | -0.66 | 0.10 | 0.62 | FALSE |
2 | The Cancer Genome Atlas | Lung Adenocarcinoma | SLC11A1 | 0.03 | 0.03 | blup | 51 | 0.03 | 0.00014 | 4.7 | 5.7 | 1.1e-08 | 0.66 | 0.04 | 0.72 | TRUE |