Best TWAS P=5.04e-08 · Best GWAS P=3.3e-10 conditioned to 0.613
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Lung | IFT57 | 0.13 | 0.02 | enet | 33 | 0.03 | 1.4e-03 | -1.9 | -5.2 | 1.6e-07 | -0.34 | 0.36 | 0.16 | TRUE |
2 | GTEx | Skin Sun Exposed Lower leg | DZIP3 | 0.07 | 0.07 | lasso | 4 | 0.07 | 2.7e-06 | 5.1 | 5.3 | 1.3e-07 | 0.71 | 0.37 | 0.55 | FALSE |
3 | GTEx | Whole Blood | DZIP3 | 0.06 | 0.05 | lasso | 3 | 0.07 | 7.9e-07 | 5.1 | 5.4 | 7.9e-08 | 0.78 | 0.53 | 0.47 | FALSE |
4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | MYH15 | 0.11 | 0.07 | blup | 108 | 0.09 | 9.7e-10 | 6.2 | 5.4 | 5.0e-08 | 0.87 | 0.01 | 0.99 | TRUE |