TWAS hub - DZIP3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0510	0.0200	1.5e-03	0.009	0.029	0.017	0.028	0.019	2.6e-02	1.6e-04	3.4e-03	1.9e-04	1.9e-03
2	GTEx	Adipose Subcutaneous	0.0660	0.0270	2.1e-03	0.015	NA	0.012	NA	0.019	2.0e-02	NA	3.3e-02	NA	9.7e-03
3	GTEx	Skin Sun Exposed Lower leg	0.0690	0.0280	1.5e-03	0.074	NA	0.053	NA	0.068	1.0e-06	NA	3.2e-05	NA	2.6e-06
4	GTEx	Whole Blood	0.0650	0.0250	5.8e-04	0.052	NA	0.060	NA	0.067	1.4e-05	NA	3.1e-06	NA	7.9e-07
5	METSIM	Adipose	0.0804	0.0245	1.8e-08	0.082	0.064	0.076	0.072	0.080	2.8e-12	7.4e-10	1.9e-11	5.6e-11	5.9e-12
6	NTR	Blood	0.0411	0.0130	8.4e-08	0.035	0.024	0.041	0.034	0.040	1.6e-11	1.8e-08	2.8e-13	3.1e-11	5.9e-13
7	YFS	Blood	0.0323	0.0117	1.8e-05	0.021	0.017	0.007	0.016	0.015	1.7e-07	2.7e-06	1.7e-03	3.1e-06	8.9e-06
8	TCGA	Brain Lower Grade Glioma	0.0300	0.0183	6.0e-03	-0.001	0.012	-0.002	NA	-0.001	4.8e-01	1.5e-02	5.7e-01	NA	4.0e-01
9	TCGA	Lung Adenocarcinoma	0.0425	0.0224	9.8e-04	0.038	0.026	0.031	NA	0.031	2.6e-05	4.7e-04	1.4e-04	NA	1.2e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Arm fat percentage (right)	3.7	14.6	28.8	-1.2	2.7	5.3	5.4	4.3	3.8	1.5	2.9	4.8
Arm fat mass (right)	3.2	13.2	25.9	-1.6	2.4	4.9	5.1	4.1	3.8	1.0	2.5	4.6
Arm fat percentage (left)	3.2	12.6	26.7	-1.2	2.6	5.2	5.1	3.9	3.3	1.1	2.5	4.4
Type 2 Diabetes (T2D) (2018)	3.1	5.7	11.8	0.1	2.0	3.4	3.3	2.4	1.9	0.9	2.3	3.1
Waist circumference	3.1	11.2	20.8	-1.8	2.6	4.4	4.6	3.8	3.8	1.0	2.0	4.1
Ever smoked	3.1	5.5	9.7	-1.2	0.1	2.6	3.0	3.1	2.4	1.8	2.0	3.1
BMI	3.0	17.3	36.0	-0.5	2.8	6.0	6.0	4.5	4.7	1.2	1.9	5.4
Diabetes (self-reported)	3.0	4.7	9.2	0.4	2.1	3.0	2.9	2.3	2.4	0.6	1.2	2.7
Hip circumference	3.0	13.1	26.6	-1.3	3.3	5.1	5.2	4.0	3.2	0.9	2.7	4.4
Diabetes diagnosed by doctor	2.9	4.7	8.2	0.5	1.8	2.9	2.9	2.4	2.5	1.1	1.1	2.8
Arm fat mass (left)	2.9	11.9	23.9	-1.7	2.5	4.9	4.9	3.8	3.4	0.7	2.4	4.3
Trunk fat mass	2.8	12.0	25.4	-1.5	2.1	5.0	5.0	3.8	3.2	1.2	2.3	4.3
Seen doctor (GP) for nerves, anxiety, tension or depression	2.8	4.2	7.0	1.3	0.5	2.4	2.5	2.0	2.1	2.6	1.3	2.6
Commuting to job workplace: Car/motor vehicle	2.7	3.1	5.7	0.0	0.7	1.0	1.7	2.4	2.2	1.9	2.0	2.3
Osteoporosis (self-reported)	2.7	3.3	5.9	-1.4	-2.4	-1.2	-1.6	-2.1	-1.9	-2.1	-1.2	-2.0
Leg fat mass (left)	2.7	10.5	21.1	-1.4	1.8	4.5	4.6	3.7	3.5	1.0	2.0	4.1
Sensitivity / hurt feelings	2.6	4.5	10.2	1.0	1.3	1.5	2.1	2.5	2.3	3.2	1.8	2.5
Whole body fat mass	2.6	10.9	22.7	-1.5	2.0	4.8	4.7	3.6	3.2	1.0	2.2	4.1
Body fat percentage	2.5	9.9	21.9	-1.1	2.1	4.7	4.5	3.4	2.9	1.0	2.2	3.8
Ever taken oral contraceptive pill	2.5	2.8	5.9	-0.2	-1.0	-2.4	-2.3	-2.4	-1.9	-0.5	-0.4	-1.9
LDL Cholesterol	2.4	3.7	11.1	0.3	3.3	1.8	2.1	1.9	1.4	-0.7	2.1	2.1
Body mass index (BMI)	2.4	10.2	20.8	-1.4	2.3	4.5	4.6	3.5	3.4	0.5	1.9	4.0
Leg fat mass (right)	2.4	9.3	19.2	-1.5	1.7	4.4	4.3	3.4	3.2	0.8	1.9	3.8
Trunk fat percentage	2.3	9.3	21.8	-1.0	2.1	4.7	4.5	3.3	2.7	1.1	1.9	3.7
Weight	2.3	11.2	22.1	-2.0	2.3	4.5	4.7	3.8	3.4	0.8	2.3	4.2
Leg pain on walking	2.3	2.9	8.2	0.7	1.2	2.9	2.5	1.3	1.0	-0.2	1.8	1.9
Supplements: Vitamin C	2.3	2.7	12.0	-0.8	-0.9	-0.1	-0.8	-2.0	-1.9	-3.5	-0.8	-1.5
Heart attack	2.2	2.8	6.0	2.4	1.6	1.3	1.4	1.7	2.2	1.6	0.3	1.8
Medication: Gliclazide	2.2	2.5	5.8	0.7	0.8	2.4	2.2	1.8	1.5	1.1	0.8	1.9
Leg fat percentage (left)	2.2	8.0	17.4	-1.3	1.9	4.2	4.0	3.0	2.7	0.5	2.2	3.4
Heart attack/myocardial infarction (self-reported)	2.1	2.7	5.6	2.4	1.6	1.5	1.5	1.6	2.0	1.4	0.2	1.7
Past tobacco smoking	2.0	3.6	6.2	1.3	0.3	-2.1	-2.4	-2.4	-2.1	-1.2	-1.7	-2.5
Major Depression (MDD)	1.9	2.3	3.3	1.0	1.5	1.1	1.4	1.6	1.8	1.8	1.6	1.7
Hypothyroidism (self reported)	1.9	4.3	13.5	-0.1	-3.7	-3.2	-2.3	-0.5	-1.2	2.1	1.2	-1.4
Frequency of depressed mood in last 2 weeks	1.9	2.7	4.8	-1.1	0.8	1.9	2.1	1.9	1.8	-0.2	1.7	2.2
Falls in the last year	1.9	2.5	4.8	0.1	-1.3	-2.0	-2.2	-1.7	-1.3	-1.6	-1.0	-2.0
Smoking status: Previous	1.9	2.8	5.0	-0.3	0.3	1.7	2.0	2.2	1.8	1.3	1.9	2.1
Mood swings	1.9	3.5	5.3	0.7	2.2	1.8	2.1	2.3	1.9	1.5	1.6	2.3
Fractured/broken bones in last 5 years	1.9	2.5	6.0	-2.5	-1.1	-1.2	-1.6	-1.7	-1.9	-1.4	-0.7	-1.5
Allergy or Eczema	1.8	4.9	9.7	0.4	2.3	2.7	2.6	2.0	2.0	3.1	0.7	2.4
Relative age of first facial hair	1.8	3.6	7.3	-0.2	-2.2	-1.5	-2.0	-2.7	-2.2	-1.2	-1.4	-2.4
Allergy	1.8	4.1	9.6	-0.6	-2.6	-1.8	-1.9	-1.9	-2.2	-3.1	-0.7	-2.0
Hayfever/allergic rhinitis (self-reported)	1.8	2.4	6.9	-1.1	0.4	-1.8	-1.7	-1.8	-0.5	-0.6	-2.6	-1.6
Age at last live birth	1.8	2.6	5.3	-0.6	1.4	1.5	1.8	2.3	1.7	0.9	1.5	2.1
Leg fat-free mass (right)	1.8	9.5	18.0	-1.5	2.3	3.8	4.2	3.6	3.4	0.7	1.9	4.1
Ever had stillbirth, spontaneous miscarriage or termination	1.8	1.9	4.0	0.6	1.1	0.5	1.2	2.0	1.8	0.8	1.5	1.8
Commuting to job workplace: Walk	1.8	2.0	3.9	0.2	-1.3	-1.0	-1.6	-1.8	-2.0	-0.7	-1.1	-1.9
Supplements: Calcium	1.8	1.9	3.5	-0.5	-1.7	-0.7	-1.3	-1.6	-1.2	-1.3	-1.9	-1.8
Reaction Time	1.7	3.2	5.9	-0.6	1.1	2.4	2.3	1.9	1.4	2.4	1.3	2.0
Heel bone mineral density (BMD) T-score, automated (left)	1.7	3.9	6.5	-0.0	1.4	2.5	2.5	2.5	1.2	1.8	2.0	2.4
Supplements: Glucosamine	1.7	2.3	12.2	-1.4	0.0	-0.3	-0.5	-1.0	-1.8	-3.5	0.6	-1.0
Medication: Simvastatin	1.7	2.5	13.2	-1.2	-0.2	-0.6	-1.1	-1.5	-0.9	-3.6	-0.9	-1.4
Leg predicted mass (right)	1.7	8.9	16.8	-1.5	2.3	3.7	4.1	3.5	3.3	0.7	1.9	3.9
Leg fat-free mass (left)	1.6	8.3	16.2	-1.5	1.9	3.7	4.0	3.3	3.1	0.7	1.8	3.8
Hayfever, allergic rhinitis or eczema	1.6	3.5	9.2	0.6	2.0	2.2	2.1	1.4	1.6	3.0	0.2	1.9
Leg predicted mass (left)	1.6	8.2	16.1	-1.5	1.9	3.6	4.0	3.3	3.1	0.7	1.9	3.8
Supplements: Fish oil (including cod liver oil)	1.6	2.1	4.5	-0.7	-1.8	-0.5	-1.1	-1.6	-1.8	-2.1	-0.7	-1.8
Body Mass Index (BMI) (2010)	1.5	2.1	3.9	-1.3	0.5	1.8	2.0	1.6	1.7	-0.8	0.7	1.8
Leg fat percentage (right)	1.5	5.5	13.2	-1.3	1.3	3.6	3.4	2.4	2.1	0.3	1.9	2.8
Mouth/teeth dental problems: Loose teeth	1.5	1.8	3.3	-0.6	0.1	1.4	1.6	1.6	1.5	1.6	1.0	1.8
Qualifications: NVQ or HND or HNC or equivalent	1.5	1.8	5.3	-2.3	-0.2	-1.4	-1.4	-1.4	-1.0	-1.5	-0.3	-1.3
Basal metabolic rate	1.5	8.3	15.4	-2.0	1.9	3.5	3.9	3.3	3.0	0.5	2.2	3.7
Risk taking	1.5	2.2	5.7	-0.8	-1.5	-1.7	-1.7	-1.2	0.2	-1.3	-2.4	-1.4
Respiratory disease	1.4	3.0	7.4	1.3	1.5	1.5	1.6	1.5	2.7	2.3	0.4	1.7
Headache pain in last month	1.4	2.4	3.7	-0.7	1.7	1.4	1.7	1.9	1.8	-0.2	1.7	1.8
Asthma (self-reported)	1.4	2.7	6.8	1.0	2.2	1.4	1.6	1.4	2.6	1.6	0.6	1.6
Fasting Glucose	1.3	1.5	3.9	-0.4	0.9	1.3	1.4	1.3	2.0	1.2	0.3	1.5
Diabetes (mother)	1.3	1.7	6.9	0.8	-0.6	2.6	2.0	0.9	0.9	0.3	-0.4	1.2
Impedance of leg (right)	1.3	6.2	10.9	0.8	-2.3	-2.9	-3.3	-3.0	-3.0	0.2	-1.4	-3.2
Hair/balding pattern: Pattern 2	1.3	1.7	3.5	0.3	0.4	1.1	1.3	1.8	1.7	1.9	0.6	1.4
Alcohol intake versus 10 years previously	1.3	1.9	4.5	0.5	2.1	1.9	1.7	0.8	1.7	0.1	0.0	1.5
High blood pressure (siblings)	1.3	1.9	7.0	-0.8	2.6	1.1	1.2	1.5	0.7	0.3	1.4	1.3
Neck or shoulder pain in last month	1.3	1.8	4.5	1.7	-0.2	-0.4	0.3	1.6	1.4	1.8	2.1	1.1
Arm fat-free mass (left)	1.3	6.8	12.0	-1.8	1.6	3.1	3.5	3.1	2.7	0.6	2.2	3.4
Bipolar Disorder (2011)	1.2	1.2	3.1	-0.1	1.8	1.0	1.0	0.5	1.4	-1.2	-1.1	0.9
Frequency of tiredness / lethargy in last 2 weeks	1.2	1.9	5.4	0.9	0.8	0.8	1.2	1.6	2.3	1.6	0.7	1.6
Hair/balding pattern: Pattern 4	1.2	3.0	7.3	-0.4	-1.3	-1.9	-1.8	-1.8	-1.8	-2.7	-0.2	-2.0
Medication: Seretide 50 evohaler	1.2	1.3	2.7	-0.8	0.5	1.6	1.6	0.9	1.1	-0.4	1.4	1.3
Whole body fat-free mass	1.2	6.7	12.0	-2.0	1.6	3.0	3.5	3.0	2.7	0.4	2.1	3.4
Eye problems/disorders: Cataract	1.2	1.4	4.1	-0.2	-1.3	-2.0	-1.7	-1.1	-0.7	0.6	-0.3	-1.1
Arm predicted mass (left)	1.2	5.9	10.8	-1.9	1.3	2.9	3.3	2.9	2.6	0.4	1.9	3.2
Alzheimer’s Disease (in father)	1.1	1.2	4.4	2.1	-0.3	1.1	1.0	1.2	1.1	0.0	0.2	1.0
Asthma	1.1	2.2	5.4	1.0	2.2	1.2	1.3	1.2	2.3	1.3	0.5	1.5
Hypothyroidism/myxoedema (self-reported)	1.1	2.1	8.2	0.3	-2.9	-2.1	-1.6	-0.1	-0.8	1.4	0.6	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.4	2.6	-0.6	0.5	1.5	1.6	1.3	1.3	0.6	0.9	1.6
Mineral and other dietary supplements	1.1	1.4	5.3	1.2	0.7	0.3	0.6	0.9	1.6	2.3	-0.6	1.1
Whole body water mass	1.1	6.6	11.7	-2.0	1.7	3.0	3.4	3.0	2.7	0.4	2.1	3.4
Diastolic blood pressure, automated reading	1.1	3.3	7.1	0.8	1.3	2.7	2.6	1.6	1.9	1.9	-0.4	2.0
Unable to work because of sickness or disability	1.1	1.4	3.2	1.6	-0.6	1.2	1.0	0.9	1.8	1.5	-0.5	0.8
Depression (Nagel 2018)	1.0	1.5	3.6	0.0	0.8	1.3	1.6	1.4	1.9	0.3	0.4	1.7
Ulcerative Colitis (UC)	1.0	1.9	3.4	0.5	-1.4	-1.9	-1.7	-1.5	-0.7	-0.8	-1.4	-1.7
HDL Cholesterol	1.0	1.6	3.7	-0.1	-1.6	-1.1	-1.5	-1.2	-0.9	0.0	-1.9	-1.6
Neuroticism	1.0	2.3	7.7	0.8	1.0	0.1	0.9	1.8	1.7	2.8	1.3	1.7
Ever used hormone-replacement therapy (HRT)	1.0	1.2	2.2	0.0	-0.9	-0.8	-1.2	-1.5	-1.4	-0.9	-1.1	-1.4
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.2	2.4	-0.8	-0.0	1.5	1.5	1.1	1.5	-0.0	-0.0	1.4
Prospective memory result	1.0	1.2	3.8	-1.2	0.3	1.4	0.9	0.6	-0.6	-0.9	1.9	0.9
Tense / ‘highly strung’	1.0	1.7	5.4	0.3	-0.6	0.7	1.1	1.4	1.2	2.3	1.5	1.4
Arm predicted mass (right)	1.0	5.1	9.4	-1.5	1.5	2.8	3.1	2.7	2.5	0.4	1.5	3.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.1	3.9	1.3	0.4	0.3	0.8	1.5	2.0	0.4	0.4	1.1
Medication: Atorvastatin	1.0	1.2	3.2	1.2	1.3	1.8	1.4	0.8	0.4	1.0	0.1	1.0
Bipolar Disorder (2018)	0.9	1.3	3.7	0.7	1.3	0.9	1.0	0.6	1.9	-0.6	-1.7	0.9
Medication: Metformin	0.9	1.2	2.4	0.4	1.3	1.5	1.4	1.1	1.1	0.4	0.4	1.4
Taking other prescription medications	0.9	1.3	6.0	1.1	0.0	-0.1	0.4	1.2	2.4	1.4	0.4	1.1
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	4.4	1.5	-0.3	-0.1	0.2	0.5	0.9	2.1	0.7	0.6
Neuroticism score	0.9	1.8	4.1	0.5	0.7	0.3	1.0	1.8	1.8	2.0	0.8	1.7
Depression (self-reported)	0.9	1.0	5.6	0.2	-0.2	0.8	0.7	0.9	0.9	2.4	0.5	0.8
Peak expiratory flow (PEF)	0.9	2.2	4.5	0.9	0.7	1.7	1.8	1.5	2.1	1.4	0.6	1.8
Ever highly irritable/argumentative for 2 days	0.9	1.1	2.2	-0.1	0.3	0.9	1.2	1.2	0.7	1.3	1.5	1.4
Arm fat-free mass (right)	0.9	4.4	8.3	-1.7	1.4	2.6	2.9	2.4	2.2	0.2	1.4	2.7
Number of children fathered	0.9	1.0	2.3	0.3	-0.1	1.1	1.2	1.2	0.4	0.7	1.5	1.4
Medication: Paracetamol	0.9	1.5	5.5	-1.7	0.8	-0.7	-0.8	-0.7	-1.0	-2.3	-0.4	-1.2
Commuting to job workplace: Cycle	0.9	1.1	4.1	2.0	-0.8	0.5	0.5	0.2	0.6	1.6	-1.2	0.2
Neuroticism (Nagel 2018)	0.8	1.9	10.0	0.3	0.7	0.2	0.7	1.3	1.3	3.2	0.8	1.2
Prostate Cancer	0.8	1.1	1.7	-1.0	-0.9	-1.3	-1.2	-0.6	-1.2	-1.3	0.7	-1.1
Qualifications: CSEs or equivalent	0.8	1.0	3.9	-1.5	0.5	0.8	0.9	0.4	0.1	-2.0	1.0	0.6
Medication: Levothyroxine sodium	0.8	1.4	4.0	-0.1	-2.0	-1.5	-0.8	0.8	-0.4	1.8	1.4	-0.0
Trunk fat-free mass	0.8	4.5	7.5	-2.3	1.1	2.2	2.7	2.4	2.1	0.0	2.1	2.7
Medication: Lansoprazole	0.8	0.9	1.7	-1.3	0.2	-1.2	-1.0	-0.8	-0.9	-0.4	1.2	-0.6
Trunk predicted mass	0.8	4.5	7.5	-2.3	1.1	2.2	2.7	2.4	2.1	0.1	2.0	2.7
Birth weight of first child	0.8	1.5	3.3	-0.3	-0.2	1.8	1.8	1.2	0.3	0.0	1.7	1.5
Medication: Paracetamol	0.8	1.3	4.5	-0.3	0.3	-0.7	-1.0	-1.2	-0.7	-2.1	-1.3	-1.6
Angina (self-reported)	0.8	1.0	1.6	0.0	0.9	1.3	1.1	0.8	0.7	-1.2	1.2	1.1
Mean time to correctly identify matches	0.8	1.6	3.2	-1.6	0.7	1.1	1.1	1.2	0.4	1.8	1.7	1.1
Ever had bowel cancer screening	0.8	0.9	1.6	-1.0	-1.3	-1.2	-1.3	-0.9	-0.8	-0.1	0.0	-1.0
Medication: Aspirin	0.8	1.0	4.5	2.1	0.8	0.4	0.6	0.9	1.4	0.4	-0.1	0.8
Wears glasses or contact lenses	0.8	0.9	4.4	-0.0	-0.0	-1.2	-0.9	-0.1	-1.1	0.6	2.1	-0.4
Tinnitus: Yes, now most or all of the time	0.8	1.0	5.0	0.3	2.2	0.7	0.7	0.5	0.2	-1.0	1.0	0.7
Alcohol drinker status: Never	0.8	1.0	4.0	0.4	-0.8	-2.0	-1.6	-0.5	-0.3	0.1	-0.0	-1.1
Schizophrenia vs Biploar Disorder	0.7	0.9	4.3	-1.2	-0.5	0.8	0.6	0.1	-0.9	0.4	2.1	0.4
Coronary Artery Disease (CAD)	0.7	0.8	2.0	1.4	0.5	0.7	1.1	0.8	1.3	0.3	0.6	0.7
Neuroticism (2016)	0.7	1.1	4.8	0.3	-1.4	-0.7	-0.6	0.2	-0.7	2.2	1.3	-0.2
Type 2 Diabetes (T2D) (2012)	0.7	0.8	3.5	0.2	-1.0	0.6	0.3	-0.2	1.3	-0.8	-1.9	0.2
Blood Eosinophil Count	0.7	5.4	11.2	2.3	2.9	1.9	2.4	2.6	3.3	1.4	0.0	2.5
Other serious medical condition/disability diagnosed by doctor	0.7	1.0	2.2	0.4	-1.1	-1.5	-1.4	-0.9	-0.1	0.5	-0.7	-1.2
Supplements: Zinc	0.7	0.7	2.0	1.0	-1.1	1.1	0.7	0.0	0.8	0.2	-1.4	0.4
Medication: Co-codamol	0.7	0.9	3.1	-1.0	-0.3	0.1	-0.3	-0.9	-1.2	-1.8	1.0	-0.6
Pack years adult smoking proportion	0.7	1.0	5.5	-0.4	-0.6	-0.5	-0.7	-0.9	-0.6	-2.4	-0.6	-0.8
Fed-up feelings	0.7	1.3	3.0	-0.5	0.9	0.6	1.1	1.4	1.7	1.1	0.1	1.5
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.5	2.6	0.4	1.1	1.4	1.6	1.6	1.1	1.2	0.7	1.5
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	1.9	0.2	-0.4	1.2	1.1	0.7	-0.3	1.4	1.4	1.0
Fluid intelligence score	0.7	1.4	3.7	0.0	1.0	-1.9	-1.6	-0.9	-1.1	1.3	-0.2	-1.3
Time employed in main current job	0.7	0.8	2.4	1.5	0.8	0.8	0.8	1.0	0.5	0.4	0.8	0.7
Hair/balding pattern: Pattern 3	0.7	1.0	3.8	1.2	0.5	0.2	0.4	0.8	1.0	2.0	0.6	1.0
Length of working week for main job	0.7	0.7	1.5	1.0	1.0	0.8	0.8	0.5	0.9	1.2	0.4	1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	3.2	0.3	-1.8	0.6	0.1	-0.6	-0.8	1.2	-0.9	-0.5
Age at first live birth	0.7	1.2	3.4	-1.0	1.4	0.8	1.0	1.2	0.4	0.8	1.8	1.0
Chest pain or discomfort	0.7	1.0	4.3	0.1	1.1	-0.0	0.4	1.3	2.1	0.8	0.3	1.0
Average weekly red wine intake	0.7	1.1	3.6	0.8	-0.1	0.5	0.9	1.1	1.4	1.9	0.4	1.1
Handedness (chirality/laterality): Left-handed	0.7	0.8	3.1	1.0	0.6	-0.0	0.4	1.4	1.8	0.2	0.4	0.9
Miserableness	0.7	1.3	2.1	1.1	1.4	1.0	1.2	0.9	1.4	1.4	-0.3	1.0
Guilty feelings	0.7	1.0	3.0	0.2	-0.1	0.3	0.8	1.7	1.6	0.9	0.8	1.2
Hearing aid user	0.7	0.7	2.2	0.3	-1.1	-1.4	-0.9	-0.2	0.2	1.5	-0.2	-0.6
Basal cell carcinoma (self-reported)	0.7	0.8	4.5	0.1	0.8	-0.6	-0.2	-0.1	1.3	-0.1	-2.1	-0.2
Depressed Affect (Nagel 2018)	0.6	1.3	5.1	0.2	1.0	0.4	0.7	1.4	1.3	2.3	0.1	1.2
Irritable Bowel Disease (IBD)	0.6	1.3	3.9	1.2	-0.6	-2.0	-1.7	-1.1	-0.1	-0.2	-0.5	-1.4
Primary Biliary Cirrhosis	0.6	0.9	2.2	1.1	1.1	0.8	0.7	0.4	1.2	0.0	-1.5	0.5
Smoking Status	0.6	1.5	3.4	-1.4	-0.9	1.1	1.3	1.6	1.8	-0.2	0.2	1.5
Ever had hysterectomy (womb removed)	0.6	0.7	1.9	0.1	-1.1	0.3	-0.4	-0.9	-1.2	-1.4	0.4	-0.5
Angina	0.6	0.8	2.8	-0.1	0.8	1.1	0.8	0.5	0.4	-1.7	0.9	0.7
Medication for hormone replacement therapy	0.6	0.6	2.1	1.3	-0.4	0.1	0.0	-0.7	0.1	1.1	-1.5	-0.0
Age when periods started (menarche)	0.6	1.3	3.8	-1.9	-0.3	-1.1	-1.0	-0.7	-0.9	-2.0	0.6	-0.9
Impedance of leg (left)	0.6	2.9	5.4	0.9	-1.4	-2.1	-2.3	-1.8	-2.0	0.7	-0.9	-2.2
Medication: Cholesterol lowering	0.6	0.9	4.2	-0.3	-0.3	0.9	0.1	-1.4	-0.8	-2.0	-0.4	-0.8
Exposure to tobacco smoke at home	0.6	0.7	1.8	1.3	-0.3	-0.7	-0.2	0.4	1.4	1.2	-0.4	0.3
Loud music exposure frequency	0.6	0.6	5.2	2.3	0.3	0.4	0.4	0.1	0.1	0.3	0.2	0.2
Medication: Ventolin 100micrograms inhaler	0.6	0.7	1.4	0.6	0.2	0.9	1.2	0.7	0.6	1.0	0.9	1.1
Worry too long after embarrassment	0.6	1.0	4.0	0.6	0.6	0.4	0.8	1.1	0.7	2.0	1.0	1.1
Wheeze or whistling in the chest in last year	0.6	1.1	3.0	1.2	1.2	1.2	1.1	0.9	1.7	0.1	-0.1	1.1
Health satisfaction	0.6	0.8	2.2	0.2	-1.5	-0.6	-0.5	-0.9	-0.1	-1.0	-1.2	-0.8
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	2.0	1.4	0.7	0.8	1.1	1.0	1.4	1.2	0.3	1.4
Financial situation satisfaction	0.6	0.8	4.9	-1.0	0.1	-0.0	0.0	-0.3	0.1	-2.2	0.9	0.1
Pain type(s) experienced in last month: Hip pain	0.6	0.8	3.5	0.9	-0.4	-1.9	-1.4	-0.1	0.1	-0.2	-0.0	-0.8
Ever had prostate specific antigen (PSA) test	0.6	0.7	3.6	-1.1	0.4	-0.7	-0.5	-0.2	-0.6	-1.9	0.7	-0.2
Ever depressed for a whole week	0.6	0.8	2.6	0.4	-0.6	1.6	1.2	-0.1	-0.7	1.2	-0.3	0.5
Pain experienced in last month	0.6	1.0	3.2	0.3	-0.7	-1.0	-1.1	-0.9	-1.0	0.4	-1.8	-1.2
Impedance of whole body	0.6	2.9	4.5	1.4	-1.5	-1.7	-2.1	-1.9	-2.1	0.8	-1.2	-2.1
Verbal and Numeric Reasoning (VNR)	0.5	1.2	4.8	0.1	1.4	-1.3	-0.7	0.5	-0.5	2.2	1.2	-0.1
Triglycerides	0.5	0.8	2.0	-0.1	1.4	0.6	0.9	0.8	0.6	0.4	1.3	1.0
Ulcerative Colitis	0.5	0.8	1.9	0.9	-0.6	-1.4	-1.1	-0.7	0.1	0.3	-1.0	-1.0
Lung FEV1/FVC ratio	0.5	2.4	5.9	1.2	-2.2	-1.6	-1.5	-1.3	-0.0	-0.7	-2.4	-1.5
Systolic blood pressure, automated reading	0.5	1.4	4.0	1.5	1.0	2.0	1.6	0.7	0.8	0.6	-0.4	0.9
Diabetes (father)	0.5	0.6	1.5	0.6	0.8	1.2	1.1	0.6	0.7	0.5	-0.1	0.9
Townsend deprivation index at recruitment	0.5	0.7	3.1	-0.4	-1.8	0.7	0.1	-0.9	-0.8	-0.7	-0.3	-0.4
Maternal smoking around birth	0.5	0.7	2.0	-1.1	-0.4	0.9	0.9	0.7	1.4	0.3	-0.4	1.0
Medication: Atenolol	0.5	0.7	2.2	0.2	0.8	-0.5	-0.8	-0.7	-0.7	-1.5	-0.7	-0.8
Alcohol usually taken with meals	0.5	0.8	2.8	-1.0	0.6	-0.3	-0.3	-0.2	-1.1	-1.1	1.7	-0.4
Had menopause	0.5	0.6	1.2	-0.3	-0.5	-0.7	-1.0	-0.8	-1.1	-0.5	-0.5	-1.1
Pulse rate	0.5	0.8	1.5	-1.1	1.2	0.3	0.7	1.2	1.1	0.6	0.1	0.8
Lung cancer (father)	0.5	0.6	2.5	1.2	-0.7	0.5	0.4	-0.2	0.8	0.1	-1.6	0.1
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	3.0	-0.2	0.7	0.8	0.8	0.7	0.5	1.7	1.0	0.8
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	2.1	-0.2	-0.6	-0.6	-0.6	-1.1	-0.4	0.5	-1.4	-0.6
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	2.2	0.2	0.8	0.0	0.5	1.5	0.4	1.4	0.6	1.0
Glaucoma (self-reported)	0.5	0.6	1.6	0.3	1.3	0.2	0.5	0.8	0.8	-0.8	1.1	0.7
Emphysema/chronic bronchitis	0.5	0.6	1.6	0.2	1.0	-0.2	0.2	1.2	1.3	0.3	0.4	0.7
Medication: Omeprazole	0.5	0.5	1.7	-0.8	0.4	1.3	0.6	-0.6	-0.5	-1.2	0.2	0.1
Heart disease (mother)	0.5	0.6	3.6	1.9	0.6	0.4	0.2	0.0	0.6	0.5	-0.9	0.3
Pulse rate, automated reading	0.5	1.6	3.4	-0.4	0.8	1.6	1.6	1.2	1.2	1.9	0.0	1.3
Number of full sisters	0.5	0.6	2.0	-1.4	0.4	0.7	0.4	0.1	-0.6	-1.2	-0.6	-0.1
Medication: Aspirin	0.5	0.7	4.0	2.0	0.5	-0.2	-0.0	0.5	1.2	0.1	-0.3	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	0.9	-0.3	-0.7	-0.8	-0.9	-1.0	-0.9	0.2	-0.8	-0.8
Eye problems/disorders: Glaucoma	0.5	0.6	1.7	0.8	1.1	0.4	0.6	0.7	0.4	-0.1	1.3	0.7
Medication: Bendroflumethiazide	0.5	0.8	2.1	0.3	1.1	1.5	1.2	0.7	0.7	-0.2	0.6	1.0
Number of operations (self-reported)	0.5	0.7	1.9	-1.4	-1.1	0.2	-0.3	-0.6	-0.7	-1.4	-0.3	-0.4
Age started oral contraceptive pill	0.5	0.6	2.3	-0.9	0.4	0.6	-0.2	-0.7	-1.5	-0.8	0.1	-0.6
Cholesterol lowering medication	0.5	0.8	2.5	0.2	1.4	-0.0	0.1	0.9	1.1	-1.6	0.1	0.5
Pack years of smoking	0.5	0.7	3.6	-0.2	-0.5	-0.5	-0.6	-0.8	-0.7	-1.9	-0.1	-0.7
Bipolar Disorder or Schizophrenia	0.4	0.9	2.5	0.4	0.8	1.2	1.4	0.7	1.6	0.3	-0.3	1.1
Alzheimer’s Disease (in mother)	0.4	0.4	1.0	-0.4	-1.0	-0.4	-0.5	-0.5	-0.9	-0.3	0.9	-0.6
Mean Putamen Volume	0.4	0.4	1.6	-1.3	-0.6	-0.2	0.2	0.2	-0.2	0.5	1.2	0.4
Schizophrenia (2014)	0.4	1.0	1.9	-0.5	0.6	1.3	1.4	0.8	0.9	0.7	1.1	1.1
Waist Hip Ratio (WHR)	0.4	1.8	5.8	-0.7	0.7	0.1	0.8	1.8	2.4	1.7	0.9	1.4
Systolic Blood Pressure	0.4	2.0	7.8	2.8	1.0	1.4	0.9	-0.7	0.9	1.3	-1.9	-0.1
Severe depression (siblings)	0.4	0.4	1.4	0.6	-0.5	0.9	0.6	-0.0	0.8	0.3	-1.2	0.3
Current tobacco smoking	0.4	0.6	2.0	-1.1	-1.4	0.3	0.1	0.2	0.3	-1.4	-0.4	0.2
Average weekly fortified wine intake	0.4	0.4	1.3	-1.1	0.8	0.9	0.8	0.6	0.2	0.1	0.1	0.5
Number of incorrect matches in round	0.4	0.6	2.8	-1.7	-0.7	0.4	0.4	0.5	0.2	-1.0	0.6	0.3
Hearing difficulty/problems with background noise	0.4	0.7	2.5	-1.5	-0.2	-0.4	-0.3	0.4	-0.8	-0.6	1.6	-0.0
Father’s age at death	0.4	0.5	0.8	-0.8	-0.9	-0.8	-0.8	-0.9	-0.9	-0.3	-0.2	-0.5
Happiness	0.4	0.4	2.5	-0.2	-1.6	0.2	0.2	-0.3	0.1	-0.2	-1.1	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.4	2.5	1.1	0.6	1.4	1.5	1.1	1.2	1.6	0.1	1.5
Pulse wave Arterial Stiffness index	0.4	0.4	0.8	-0.2	-0.1	0.5	0.8	0.9	0.6	0.8	0.8	0.8
Blood clot in the leg (DVT)	0.4	0.5	1.7	-0.5	-0.5	-1.3	-0.9	-0.1	0.3	0.5	-0.8	-0.5
Birth weight	0.4	0.8	2.2	-0.5	-0.3	1.2	0.9	0.5	-0.1	-1.5	1.5	0.5
Chronic bronchitis/emphysema (mother)	0.4	0.4	2.0	-0.2	-0.0	0.1	-0.3	-0.5	-0.1	-1.2	-1.4	-0.4
Forced vital capacity (FVC), Best measure	0.4	1.5	2.5	0.6	1.3	1.5	1.6	1.3	1.1	1.1	0.3	1.6
Number of full brothers	0.4	0.5	2.1	-0.2	0.3	1.5	1.2	0.7	0.3	-0.2	0.1	0.7
Qualifications: College or University degree	0.4	1.2	4.6	0.9	-0.6	-1.4	-1.1	-0.8	-0.2	2.1	-0.9	-0.6
Migraine (self-reported)	0.4	0.5	1.8	-0.7	-0.5	0.2	-0.1	-1.0	-0.5	-0.6	-1.3	-0.6
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	2.7	-0.4	-0.6	-0.4	-0.5	-0.5	-1.6	0.2	-0.0	-0.9
Long-standing illness, disability or infirmity	0.4	0.6	2.1	1.0	0.5	0.6	0.5	0.5	0.9	1.4	-0.2	0.7
Breast cancer (self-reported)	0.4	0.4	1.1	-0.4	-0.4	-0.7	-0.7	-0.3	-0.9	-1.1	0.6	-0.5
Smoking status: Current	0.4	0.6	2.0	-1.3	-1.4	0.4	0.1	0.2	0.5	-1.1	-0.7	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	3.2	1.8	0.9	0.6	0.7	0.8	0.6	0.8	-0.5	0.9
Irritability	0.4	0.7	1.8	-1.0	0.4	1.4	1.2	0.5	0.4	0.7	0.3	1.1
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.4	-0.9	0.0	1.0	0.3	-0.8	-0.6	-1.2	-0.3	-0.1
Intelligence (Savage-Jansen 2018)	0.3	0.9	2.4	-0.4	0.0	-1.5	-1.2	-0.6	-0.8	1.5	0.5	-0.8
Worry (Nagel 2018)	0.3	0.7	5.3	0.1	-0.0	-0.5	0.0	0.4	0.7	2.3	0.3	0.4
Ovarian Cancer	0.3	0.3	1.4	1.1	-0.1	-0.1	-0.0	0.2	0.2	1.2	0.4	0.0
HbA1C	0.3	0.3	1.6	0.1	0.8	-1.2	-0.7	-0.1	-0.2	-0.4	0.1	-0.4
Lupus	0.3	0.5	1.8	-0.5	-0.8	-0.6	-0.4	0.1	-0.8	0.5	1.3	-0.3
Rheumatoid Arthritis	0.3	0.5	1.7	-1.1	-0.5	-0.0	-0.0	-0.1	-1.1	0.0	1.3	-0.0
Cardiovascular Disease	0.3	0.8	1.9	-0.7	1.1	-0.2	-0.6	-1.3	-0.3	-0.9	-1.4	-0.8
Tanning	0.3	3.1	5.6	-1.1	-2.4	-2.4	-2.1	-1.6	-0.9	-1.6	-1.4	-1.7
Vitamin and mineral supplements	0.3	0.5	1.3	0.1	0.7	0.2	0.5	0.8	0.8	1.1	0.6	0.7
Hand grip strength (right)	0.3	0.9	2.8	-0.1	0.6	1.7	1.6	0.8	0.7	0.1	-0.1	1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.3	1.3	-1.2	-1.1	-0.1	0.0	0.0	0.6	-0.5	-0.0	0.2
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	2.2	1.5	-0.4	0.2	-0.1	-0.6	-0.4	0.4	-0.6	-0.2
Stomach or abdominal pain in last month	0.3	0.3	1.4	0.3	-0.9	-0.3	-0.0	0.2	1.2	0.7	0.2	0.4
Chronic bronchitis/emphysema (father)	0.3	0.4	0.9	0.7	-0.1	0.7	0.6	0.4	1.0	0.5	-0.5	0.6
High blood pressure (mother)	0.3	0.4	1.1	0.6	-0.3	-0.8	-0.3	0.4	1.1	0.9	0.2	0.1
Nervous feelings	0.3	0.6	3.5	0.1	-0.0	-0.9	-0.3	0.5	0.8	1.9	0.2	0.4
Qualifications: None of the above	0.3	0.6	2.3	0.4	-1.2	0.2	-0.2	-0.2	-0.1	-1.5	-0.9	-0.5
Illnesses of siblings	0.3	0.4	1.0	0.4	-0.7	-1.0	-0.8	-0.6	-0.7	0.1	0.2	-0.7
Number of live births	0.3	0.5	1.5	-0.2	-1.0	-0.2	-0.6	-0.1	-0.3	-1.2	-0.9	-0.6
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	3.3	1.2	-0.4	0.8	1.0	0.8	0.9	1.8	-0.1	1.0
Noisy workplace	0.3	0.4	1.3	0.4	0.2	1.1	0.8	0.3	0.2	-0.6	0.5	0.5
Mouth/teeth dental problems: Dentures	0.3	0.5	1.8	-1.3	-0.9	-0.5	-0.5	0.1	-0.2	-1.1	-0.3	-0.4
Illnesses of mother	0.3	0.4	2.0	-0.8	0.1	0.3	0.5	0.5	-0.3	0.5	1.4	0.5
Impedance of arm (left)	0.3	1.5	3.2	1.2	-0.9	-1.0	-1.4	-1.4	-1.8	0.6	-0.9	-1.5
Breastfed as a baby	0.3	0.4	1.5	-0.6	-0.0	0.8	0.5	0.2	0.6	1.2	0.0	0.5
Pulse wave reflection index	0.3	0.3	1.2	-0.0	0.3	0.6	0.2	-0.6	-1.1	-0.5	0.7	-0.2
Exposure to tobacco smoke outside home	0.3	0.4	1.3	0.0	1.2	0.5	0.6	0.4	0.8	-0.2	0.7	0.7
Pulse wave peak to peak time	0.3	0.4	0.7	0.0	0.1	-0.5	-0.7	-0.8	-0.5	-0.8	-0.7	-0.7
Shortness of breath walking on level ground	0.3	0.4	0.9	-0.6	0.2	0.6	0.5	0.6	0.8	-1.0	0.4	0.5
Medication for pain relief, constipation, heartburn	0.3	0.5	1.7	-1.3	-0.4	0.1	0.2	-0.2	-1.1	0.3	1.0	0.1
Medication: Allopurinol	0.3	0.4	1.0	-0.2	0.3	0.6	0.7	0.6	1.0	0.6	-0.6	0.6
Family relationship satisfaction	0.3	0.4	1.5	0.3	-1.2	0.5	0.2	-1.0	-0.3	-0.5	-0.1	-0.3
Illnesses of siblings: Diabetes	0.3	0.4	1.8	0.7	-0.6	0.0	-0.2	-0.2	-0.0	-1.3	-0.7	-0.3
Medication for cholesterol	0.3	0.5	2.3	0.1	-0.7	0.7	0.6	0.5	-0.1	0.6	1.5	0.4
Illnesses of father: None of the above (group 1)	0.3	0.4	1.0	-0.1	-0.0	-0.4	-0.4	-0.6	-1.0	0.8	0.9	-0.6
Average weekly champagne plus white wine intake	0.3	0.4	1.7	0.6	0.3	-0.1	0.4	0.7	0.4	0.5	1.3	0.6
Medication: Blood pressure	0.3	0.6	1.3	-0.7	1.1	-0.5	-0.7	-0.8	-0.9	-0.9	-0.2	-0.6
High cholesterol (Self-reported)	0.3	0.6	3.3	0.4	0.6	0.3	-0.2	-0.7	-0.1	-1.8	-0.7	-0.5
Illnesses of father: High blood pressure	0.3	0.4	2.6	-0.3	0.1	-0.0	0.1	0.0	0.8	0.2	-1.6	0.2
Myopia	0.3	0.5	1.7	-1.3	-0.7	0.0	-0.3	-1.0	-0.7	0.3	-0.6	-0.5
Alcohol drinker status: Previous	0.3	0.4	2.4	-0.3	-1.6	0.0	0.0	-0.2	-0.3	-0.2	0.8	-0.2
Schizophrenia (2018)	0.2	0.5	1.0	-0.1	-0.1	0.8	1.0	0.5	0.5	0.8	0.9	0.7
Alzheimer’s Disease (including proxy)	0.2	0.2	0.9	0.4	-1.0	-0.1	-0.3	-0.1	-0.3	-0.6	0.6	-0.3
Crohns Disease (2017)	0.2	0.5	1.1	1.1	0.3	-1.0	-0.7	-0.0	0.9	0.3	0.6	-0.4
Age at First Birth	0.2	0.2	1.7	-0.4	0.5	-0.2	-0.1	0.1	-0.1	-0.2	1.3	0.0
Crohns Disease (2012)	0.2	0.3	1.5	0.4	1.2	-0.4	-0.2	0.1	1.1	0.1	-0.1	-0.1
Blood Platelet Count	0.2	2.0	4.2	-1.4	1.8	0.8	1.1	1.2	0.6	2.1	1.8	1.2
Chronotype (morning person)	0.2	0.6	2.1	-0.3	-0.5	-1.4	-1.2	-0.4	-0.2	0.2	-0.7	-0.6
Hand grip strength (left)	0.2	0.5	0.8	0.0	0.6	0.7	0.9	0.7	0.8	-0.7	0.3	0.9
Eye problems/disorders: Diabetes related eye disease	0.2	0.3	0.5	0.3	0.6	0.6	0.5	0.7	0.5	0.5	-0.0	0.5
Relative age voice broke	0.2	0.3	0.8	0.5	-0.1	0.7	0.5	0.4	-0.0	0.9	0.8	0.4
Serious illness, injury or assault to yourself	0.2	0.2	0.6	-0.2	0.2	0.8	0.4	-0.4	0.3	-0.7	-0.8	0.0
Multivitamins +/- minerals	0.2	0.2	1.0	1.0	-0.5	0.3	0.1	-0.1	0.2	-0.2	-0.8	0.0
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.6	0.1	0.3	0.3	0.4	0.4	0.8	0.7	-0.2	0.5
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.8	0.7	-0.1	0.4	0.5	0.4	0.9	0.7	0.3	0.7
Had other major operations	0.2	0.3	1.0	0.3	-0.9	-0.1	-0.1	0.7	-0.0	1.0	0.1	0.0
Forced vital capacity (FVC)	0.2	0.6	1.4	0.3	0.1	1.0	1.0	0.9	0.5	1.2	0.2	1.1
Financial difficulties in last 2 years	0.2	0.2	0.7	-0.9	-0.8	-0.6	-0.4	0.0	0.3	-0.2	-0.0	-0.0
Mouth/teeth dental problems	0.2	0.3	1.2	0.5	1.0	-0.1	0.2	0.4	0.0	0.2	1.1	0.4
Pain all over the body in last month	0.2	0.3	0.8	0.2	0.7	0.6	0.5	0.2	0.9	0.3	-0.3	0.4
Worrier / anxious feelings	0.2	0.3	1.6	0.3	0.2	-0.8	-0.3	0.4	0.4	1.3	0.1	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	0.6	0.5	0.4	-0.8	-0.3	0.7	0.8	0.4	0.2	0.2
Medication: Amlodipine	0.2	0.3	0.8	-0.4	-0.9	0.6	0.1	-0.5	-0.1	-0.8	-0.6	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.2	0.6	0.2	-0.5	-0.1	0.1	0.7	0.4	0.8	0.4	0.4
Eye problems/disorders: None of the above	0.2	0.3	0.8	-0.3	-0.2	0.9	0.6	-0.4	-0.9	-0.5	-0.2	-0.1
Medication: Blood pressure	0.2	0.3	1.4	1.2	-0.2	0.1	0.0	-0.2	0.9	0.4	-0.5	0.1
Suffer from ‘nerves’	0.2	0.4	1.7	-0.3	-0.2	-0.2	0.2	0.4	0.7	1.3	0.8	0.4
Overall health rating	0.2	0.5	2.4	0.3	-0.3	0.8	0.8	0.5	1.5	0.2	-0.5	0.8
Loneliness, isolation	0.2	0.3	1.0	-1.0	-0.6	-0.7	-0.7	-0.6	-0.2	-0.1	-0.4	-0.5
Friendships satisfaction	0.2	0.2	0.8	0.9	-0.6	-0.2	-0.3	-0.6	-0.5	0.3	0.2	-0.3
Qualifications: nursing, teaching	0.2	0.3	0.9	0.3	-0.9	0.7	0.3	-0.3	-0.4	0.9	-0.1	0.2
Back pain experienced in last month	0.2	0.3	1.7	0.1	1.3	0.1	0.2	0.0	0.6	-0.8	0.5	0.2
Osteoarthritis (self-reported)	0.2	0.3	1.0	-0.0	0.4	1.0	0.8	0.2	0.4	0.2	0.3	0.5
Number of self-reported non-cancer illnesses	0.2	0.3	1.1	-0.2	-0.2	-0.6	-0.8	-0.5	0.4	-0.2	-1.0	-0.7
Mother’s age at death	0.2	0.2	0.6	-0.0	-0.8	-0.5	-0.2	0.5	0.7	0.4	0.3	0.1
Average weekly beer plus cider intake	0.2	0.3	0.7	-0.4	-0.8	-0.3	-0.5	-0.4	-0.2	-0.1	-0.8	-0.6
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.7	-0.3	-0.2	-0.9	-0.5	0.1	0.6	0.8	-0.7	-0.1
Heart disease (siblings)	0.2	0.3	1.2	-0.3	0.2	-0.6	-0.7	-0.5	0.1	0.1	-1.1	-0.6
Breast Cancer	0.1	0.3	1.2	-0.6	0.0	-1.1	-0.7	0.4	0.5	0.4	-0.2	-0.2
Blood Red Count	0.1	0.7	3.8	-0.5	-0.4	-0.3	-0.5	-0.7	-0.1	-0.8	-1.9	-0.8
Blood White Count	0.1	1.0	5.0	-0.4	2.2	0.5	0.7	0.5	1.4	0.4	-0.1	0.8
Heel T-Score	0.1	0.5	1.4	-0.3	0.4	0.3	-0.1	-0.9	-1.2	-0.9	-0.5	-0.7
Lung FVC	0.1	0.7	1.6	-0.8	0.0	1.2	1.0	0.6	-0.3	-0.9	0.9	0.8
Hair Pigment	0.1	1.8	4.2	0.2	-2.1	-1.4	-1.5	-1.6	-0.9	0.5	-1.5	-1.4
Number of treatments/medications taken	0.1	0.2	0.8	0.2	0.6	-0.0	0.0	0.1	0.9	-0.6	-0.4	0.2
Average weekly spirits intake	0.1	0.1	0.4	-0.6	-0.7	0.3	0.1	-0.1	0.2	-0.2	0.1	0.1
Hearing difficulty/problems: Yes	0.1	0.2	0.4	-0.6	-0.2	0.3	0.2	0.1	-0.6	-0.6	0.4	0.0
High blood pressure	0.1	0.3	1.7	0.5	1.3	0.3	0.0	-0.1	0.3	0.4	-0.5	-0.0
Sitting height	0.1	1.0	2.0	-0.9	0.1	1.2	1.4	1.1	1.0	0.8	0.1	1.4
Medication: Ramipril	0.1	0.1	0.7	0.1	-0.9	0.5	0.1	0.0	0.0	-0.2	0.1	-0.0
Impedance of arm (right)	0.1	0.6	1.4	1.0	-0.6	-0.6	-0.8	-0.6	-0.9	1.2	-0.3	-0.7
Qualifications: A levels/AS levels or equivalent	0.1	0.2	1.1	-0.6	0.3	-0.4	-0.1	-0.0	-0.2	1.1	0.7	0.0
Standing height	0.1	0.8	2.2	-1.5	0.1	0.4	0.8	1.0	0.3	0.8	1.3	1.0
Gout (self-reported)	0.1	0.2	0.6	-0.6	0.7	-0.3	0.0	0.3	0.8	0.1	-0.1	0.4
Comparative body size at age 10	0.1	0.3	1.1	0.5	-0.6	-1.1	-0.7	0.1	0.2	0.8	0.4	-0.2
Medication: Ibuprofen	0.1	0.2	0.6	0.2	0.8	-0.6	-0.2	0.4	0.2	0.0	0.4	0.2
Alcohol intake frequency.	0.1	0.3	0.6	0.5	-0.4	-0.5	-0.6	-0.4	-0.5	-0.8	0.6	-0.6
Comparative height size at age 10	0.1	0.4	1.8	-0.7	-0.0	0.0	0.5	1.4	0.7	0.6	-0.2	0.7
Had major operations	0.1	0.2	1.1	-1.0	-0.1	0.2	0.1	-0.2	0.2	-0.5	0.1	0.1
Knee pain experienced in last month	0.1	0.2	0.4	-0.6	0.5	0.7	0.5	-0.1	0.2	-0.7	0.4	0.3
Hypertension (Self-reported)	0.1	0.3	1.8	0.4	1.4	0.0	-0.3	-0.5	-0.1	0.3	-0.2	-0.3
Illnesses of father: Heart disease	0.1	0.2	0.6	-0.8	0.5	-0.0	0.1	0.2	0.5	-0.5	0.4	0.3
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.8	-0.2	-0.9	0.2	0.2	0.3	0.3	0.7	0.4	0.3
Commuting to job workplace: Public transport	0.1	0.2	0.6	-0.8	0.4	0.2	0.2	-0.1	-0.2	-0.6	0.5	-0.0
Medication: Lisinopril	0.1	0.1	0.8	-0.1	0.9	-0.3	0.1	-0.1	0.3	-0.2	0.2	0.1
Vascular/heart problems diagnosed by doctor	0.1	0.3	2.0	-0.2	-1.4	-0.3	-0.1	0.1	-0.6	-0.4	0.3	-0.1
Height	0.0	0.9	5.3	-2.3	0.2	0.2	0.3	0.6	-0.3	0.1	1.6	0.3

Hub : Genes

DZIP3

Models

Trait associations