TWAS hub - MYH15

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Lung Squamous Cell Carcinoma	0.0406	0.0223	7.2e-03	0.002	0.016	0.000	NA	0.013	1.8e-01	5.9e-03	3.2e-01	NA	1.1e-02
2	TCGA	Pheochromocytoma and Paraganglioma	0.1110	0.0550	4.9e-03	0.006	0.022	0.023	NA	-0.004	1.8e-01	4.5e-02	4.2e-02	NA	4.9e-01
3	TCGA	Prostate Adenocarcinoma	0.1111	0.0415	3.3e-09	0.071	0.091	0.090	NA	0.084	7.3e-08	9.7e-10	1.1e-09	NA	3.8e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Ever taken oral contraceptive pill	5.4	6.0	8.9	-2.5	-1.6	-3.0
Reaction Time	4.3	8.2	13.4	1.7	3.7	2.9
Qualifications: CSEs or equivalent	3.8	5.0	13.7	-3.7	-1.0	0.5
Arm fat percentage (right)	3.8	15.1	29.7	0.3	3.9	5.4
Arm fat percentage (left)	3.5	14.0	26.2	0.6	3.9	5.1
Age started oral contraceptive pill	3.5	4.4	9.5	3.1	1.9	0.5
Major Depression (MDD)	3.3	4.0	4.7	1.9	2.2	1.9
Trunk fat mass	3.3	14.3	25.9	0.1	4.1	5.1
Trunk fat percentage	3.2	12.8	24.4	0.7	3.7	4.9
Time employed in main current job	3.2	3.7	4.9	2.0	2.2	1.5
Falls in the last year	3.1	4.3	6.0	-1.5	-2.1	-2.4
Body fat percentage	3.1	12.3	23.9	0.6	3.6	4.9
Mean time to correctly identify matches	3.1	5.9	7.1	2.4	2.7	2.2
Arm fat mass (right)	3.0	12.3	22.8	-0.4	3.7	4.8
BMI	2.9	17.0	28.1	-2.7	4.0	5.3
Whole body fat mass	2.9	12.1	21.7	0.0	3.8	4.7
Arm fat mass (left)	2.9	11.8	20.8	-0.4	3.8	4.6
Waist circumference	2.8	10.3	19.2	-0.5	3.4	4.4
Alcohol intake versus 10 years previously	2.8	4.2	6.4	-2.5	1.4	2.0
Seen doctor (GP) for nerves, anxiety, tension or depression	2.8	4.2	9.7	-0.5	3.1	1.6
Number of full brothers	2.7	3.4	9.1	-3.0	-0.4	1.0
Ever smoked	2.7	4.8	6.0	2.4	2.3	1.8
Leg fat mass (left)	2.6	10.3	18.9	-0.6	3.4	4.3
Diabetes (mother)	2.5	3.2	4.7	-1.4	2.2	1.7
Diabetes (self-reported)	2.5	3.9	6.0	-0.9	2.5	2.2
Type 2 Diabetes (T2D) (2018)	2.4	4.5	7.2	-0.7	2.7	2.4
Pack years adult smoking proportion	2.4	3.6	5.9	-2.4	-1.8	-1.3
Heel bone mineral density (BMD) T-score, automated (left)	2.4	5.6	6.9	2.6	2.0	2.4
Body mass index (BMI)	2.4	10.0	17.0	-1.1	3.4	4.1
Hip circumference	2.4	10.4	17.3	-0.8	3.7	4.2
Birth weight of first child	2.4	4.4	7.0	-0.1	2.6	2.5
Leg fat mass (right)	2.4	9.4	17.1	-0.7	3.3	4.1
Pain type(s) experienced in last month: Hip pain	2.4	3.0	6.0	-0.6	-2.4	-1.7
Diabetes diagnosed by doctor	2.3	3.8	5.4	-1.0	2.2	2.3
Medication: Levothyroxine sodium	2.1	3.5	4.8	2.2	-1.5	-1.8
Ever unenthusiastic/disinterested for a whole week	2.1	2.6	3.8	1.9	1.8	0.8
Hayfever/allergic rhinitis (self-reported)	2.1	2.8	5.9	-2.4	0.4	-1.5
Commuting to job workplace: Walk	2.1	2.2	4.0	2.0	0.5	-1.6
Leg fat percentage (left)	2.1	7.5	16.2	-0.3	2.5	4.0
Ever depressed for a whole week	2.1	2.6	4.0	1.7	2.0	0.9
Myopia	2.1	3.0	8.8	-0.4	3.0	-0.5
Bipolar Disorder (2011)	2.0	2.0	3.9	-0.9	2.0	1.1
Allergy or Eczema	2.0	5.2	8.0	0.7	2.6	2.8
Eye problems/disorders: Diabetes related eye disease	2.0	2.1	6.1	2.5	0.5	0.3
Weight	2.0	10.0	17.6	-0.8	3.4	4.2
Alcohol drinker status: Never	2.0	2.4	4.0	0.8	-2.0	-1.6
Irritability	2.0	3.4	7.3	-0.8	2.7	1.4
Hypothyroidism (self reported)	1.9	4.4	8.7	1.4	-1.5	-3.0
Chronotype (morning person)	1.8	4.1	7.7	-1.4	-2.8	-1.6
Hayfever, allergic rhinitis or eczema	1.8	3.9	6.7	0.3	2.6	2.2
Qualifications: None of the above	1.8	3.9	6.7	-2.6	-2.2	-0.0
Breastfed as a baby	1.8	2.3	3.7	1.4	1.9	1.1
Qualifications: O levels/GCSEs or equivalent	1.8	2.9	4.7	2.2	1.9	0.7
Type 2 Diabetes (T2D) (2012)	1.7	2.0	3.5	-1.9	1.5	0.4
Bilateral oophorectomy (both ovaries removed)	1.7	1.9	5.7	0.2	2.4	0.2
Back pain experienced in last month	1.7	2.5	6.0	-2.4	-1.3	-0.1
Pack years of smoking	1.7	2.5	3.4	-1.8	-1.8	-1.0
Past tobacco smoking	1.6	2.9	4.4	-1.7	-2.1	-1.2
Leg fat percentage (right)	1.6	5.6	12.4	-0.3	2.1	3.5
Eye problems/disorders: None of the above	1.6	1.9	4.2	-0.8	2.0	0.9
Average weekly red wine intake	1.6	2.3	6.0	0.7	2.5	0.6
LDL Cholesterol	1.5	2.4	5.4	-2.3	0.7	1.2
Multivitamins +/- minerals	1.5	1.9	5.0	-2.2	0.1	0.8
Had other major operations	1.5	1.8	4.9	2.2	0.8	-0.3
Serious illness, injury or assault of a close relative in last 2 years	1.5	1.7	3.1	-1.3	1.8	0.6
Lung cancer (father)	1.5	1.8	4.1	-2.0	0.8	0.7
Hypothyroidism/myxoedema (self-reported)	1.5	3.0	5.1	1.2	-1.5	-2.3
Illness, injury, bereavement, stress in last 2 years	1.5	1.9	5.0	2.2	-0.7	0.4
Leg fat-free mass (right)	1.5	8.0	10.9	-1.7	3.2	3.3
Medication: Atorvastatin	1.5	1.9	3.7	1.1	0.9	1.9
Illnesses of father: High blood pressure	1.5	1.9	5.4	-2.3	-0.5	-0.2
Bipolar Disorder or Schizophrenia	1.4	3.5	8.6	0.1	2.9	1.4
Leg fat-free mass (left)	1.4	7.5	10.1	-1.8	3.1	3.2
Average weekly fortified wine intake	1.4	1.6	4.9	0.0	2.2	0.0
Leg predicted mass (left)	1.4	7.5	10.1	-1.7	3.1	3.2
Emphysema/chronic bronchitis	1.4	1.6	4.3	0.6	-2.1	-0.3
Leg predicted mass (right)	1.4	7.6	10.2	-1.6	3.2	3.2
Bipolar Disorder (2018)	1.3	2.1	3.1	-0.4	1.7	1.8
Depression (Nagel 2018)	1.3	1.9	5.0	0.3	0.9	2.2
Qualifications: A levels/AS levels or equivalent	1.3	3.0	7.0	2.6	1.4	0.1
Mouth/teeth dental problems: Loose teeth	1.3	1.5	2.7	1.0	1.6	0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.3	1.6	1.8	-1.3	1.1	1.3
Heart attack/myocardial infarction (self-reported)	1.3	1.7	3.3	-1.3	0.3	1.8
Body Mass Index (BMI) (2010)	1.2	1.6	2.2	-1.3	1.0	1.5
Mean Putamen Volume	1.2	1.3	3.5	0.0	-1.9	-0.8
Primary Biliary Cirrhosis	1.2	1.7	4.0	-2.0	-0.0	1.0
Impedance of leg (right)	1.2	5.8	6.9	2.4	-2.6	-2.2
Heart attack	1.2	1.5	2.6	-1.4	0.1	1.6
Angina (self-reported)	1.2	1.6	3.1	-1.8	0.1	1.2
Supplements: Fish oil (including cod liver oil)	1.2	1.6	4.4	-2.1	0.1	-0.6
Ulcerative Colitis (UC)	1.1	2.1	3.4	-1.9	-0.0	-1.7
Fasting Glucose	1.1	1.3	3.8	-0.2	0.5	1.9
Relative age of first facial hair	1.1	2.2	3.9	-1.6	-0.1	-2.0
Angina	1.1	1.5	3.4	-1.8	0.3	1.0
Medication: Co-codamol	1.1	1.3	2.5	-1.6	0.9	-0.8
Medication: Metformin	1.1	1.5	2.2	-1.2	1.5	0.9
Townsend deprivation index at recruitment	1.1	1.6	4.5	0.4	2.1	-0.4
Exposure to tobacco smoke at home	1.1	1.2	1.9	-1.2	-1.4	-0.5
Pulse wave reflection index	1.1	1.4	2.1	1.1	1.4	0.9
Exposure to tobacco smoke outside home	1.1	1.5	2.9	-1.7	1.2	0.5
Commuting to job workplace: Car/motor vehicle	1.1	1.3	2.7	0.3	-1.0	1.6
Medication: Gliclazide	1.1	1.2	2.0	0.4	1.4	1.2
Basal metabolic rate	1.1	6.3	8.5	-1.8	2.7	2.9
Risk taking	1.1	1.6	3.5	-1.1	-0.4	-1.9
Diastolic blood pressure, automated reading	1.1	3.4	4.5	-1.3	2.1	2.0
Schizophrenia (2018)	1.0	2.0	5.6	0.6	2.4	0.3
Sensitivity / hurt feelings	1.0	1.8	2.7	-1.2	1.0	1.6
Frequency of depressed mood in last 2 weeks	1.0	1.3	3.9	-0.1	0.3	2.0
Ever used hormone-replacement therapy (HRT)	1.0	1.3	1.8	0.9	1.1	-1.3
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.3	2.9	1.6	1.2	1.7
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	2.8	-1.0	1.7	-0.3
Medication: Seretide 50 evohaler	1.0	1.1	1.7	0.7	1.1	1.3
Leg pain on walking	1.0	1.2	3.2	-0.5	0.3	1.8
Number of operations (self-reported)	1.0	1.4	3.8	-0.0	1.9	-0.7
Medication for hormone replacement therapy	0.9	1.0	2.3	-1.5	0.8	-0.1
Diabetes (father)	0.9	1.1	1.6	-0.8	1.2	1.1
Impedance of leg (left)	0.9	4.2	5.8	2.4	-2.2	-1.4
Alcohol usually taken with meals	0.9	1.4	3.5	1.9	0.2	-0.9
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.2	2.9	-0.8	-1.7	-0.3
Impedance of arm (left)	0.9	4.0	11.9	3.5	-0.3	-0.0
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.1	2.7	-0.6	1.6	0.4
Age at last live birth	0.9	1.4	1.8	1.3	0.9	1.3
Smoking status: Previous	0.9	1.3	2.1	1.0	1.4	0.9
Whole body fat-free mass	0.9	5.0	5.9	-1.9	2.4	2.3
Illnesses of father: None of the above (group 1)	0.9	1.2	3.1	1.7	0.4	-0.5
Whole body water mass	0.9	5.1	6.1	-1.9	2.5	2.4
Impedance of whole body	0.9	4.5	11.1	3.3	-1.4	-0.6
Schizophrenia (2014)	0.8	1.8	4.7	0.7	2.2	0.6
Lung FEV1/FVC ratio	0.8	4.1	10.2	-3.2	-0.2	-1.4
Vitamin and mineral supplements	0.8	1.0	2.2	1.5	0.7	0.6
Severe depression (siblings)	0.8	0.9	2.3	-0.2	1.5	0.7
Serious illness, injury or assault to yourself	0.8	1.0	2.5	-0.5	1.6	0.4
Supplements: Glucosamine	0.8	1.0	2.9	-1.7	-0.3	-0.4
Diverticular disease/diverticulitis (self-reported)	0.8	1.0	1.7	-0.3	1.3	1.1
Qualifications: nursing, teaching	0.8	1.3	2.2	1.5	0.7	1.1
Eye problems/disorders: Cataract	0.8	0.9	1.4	-0.4	-1.2	-1.1
Number of self-reported non-cancer illnesses	0.8	1.4	2.4	-1.3	-0.1	-1.5
Arm fat-free mass (left)	0.8	4.2	5.6	-1.7	2.1	2.4
Arm predicted mass (left)	0.8	4.2	4.8	-2.0	2.0	2.2
Lupus	0.7	1.0	2.5	1.6	0.7	-0.2
Number of treatments/medications taken	0.7	1.2	3.5	-1.9	0.3	-0.5
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	2.2	-0.5	-0.6	-1.5
Systolic blood pressure, automated reading	0.7	2.1	3.1	-0.9	1.5	1.8
Maternal smoking around birth	0.7	1.0	2.8	-1.7	0.3	0.4
Had menopause	0.7	0.9	2.0	1.4	0.2	-0.8
Allergy	0.7	1.6	3.5	-0.2	-1.1	-1.9
Fluid intelligence score	0.7	1.4	2.7	1.6	-0.1	-1.2
Illnesses of siblings	0.7	1.0	1.8	0.9	-0.6	-1.4
Medication: Cholesterol lowering	0.7	1.0	1.3	-1.2	1.0	0.9
Length of working week for main job	0.7	0.8	1.5	-0.6	1.2	0.7
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	2.6	1.6	-0.8	0.1
Age at first live birth	0.7	1.2	2.6	1.6	0.6	0.8
Medication: Blood pressure	0.7	1.3	3.6	-1.9	0.5	-0.3
Arm predicted mass (right)	0.7	3.6	4.1	-1.7	1.9	2.0
Knee pain experienced in last month	0.7	1.1	1.8	-1.3	1.2	-0.5
Breast cancer (self-reported)	0.7	0.8	2.3	1.5	0.2	0.2
Osteoarthritis (self-reported)	0.7	0.9	1.4	-1.1	1.2	0.1
Tinnitus: Yes, now most or all of the time	0.7	0.8	1.6	-1.3	0.9	-0.2
Age at First Birth	0.6	0.8	2.1	1.5	0.5	0.1
HDL Cholesterol	0.6	0.9	2.3	0.2	-0.7	-1.5
Triglycerides	0.6	1.0	2.1	-0.3	1.4	1.0
Ulcerative Colitis	0.6	0.8	1.7	-1.3	0.0	-0.9
Hand grip strength (right)	0.6	1.5	2.3	-1.4	0.6	1.5
Medication: Simvastatin	0.6	0.9	2.5	-1.6	0.2	-0.2
Trunk fat-free mass	0.6	3.2	4.3	-2.1	1.8	1.5
Depression (self-reported)	0.6	0.8	1.5	0.4	1.2	0.8
Medication: Lansoprazole	0.6	0.7	1.2	0.3	-1.1	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	3.0	-1.1	1.2	1.7
Trunk predicted mass	0.6	3.2	4.1	-2.0	1.8	1.5
Hair/balding pattern: Pattern 4	0.6	1.5	2.6	-0.5	-1.2	-1.6
High blood pressure (siblings)	0.6	0.9	2.2	-0.1	0.7	1.5
Arm fat-free mass (right)	0.6	3.3	3.6	-1.9	1.8	1.7
Supplements: Vitamin C	0.6	0.7	1.3	0.2	-0.8	-1.1
Friendships satisfaction	0.6	0.7	1.3	1.1	-0.5	-0.8
Osteoporosis (self-reported)	0.6	0.7	1.5	0.4	0.6	-1.2
Average weekly champagne plus white wine intake	0.6	0.8	1.0	0.5	-1.0	-1.0
Wears glasses or contact lenses	0.6	0.7	0.8	0.7	-0.9	-0.8
Medication: Paracetamol	0.6	0.9	2.0	0.2	0.9	-1.4
Pain experienced in last month	0.6	0.9	2.0	1.4	-0.9	-0.3
Alzheimer’s Disease (in father)	0.5	0.6	1.5	0.2	0.5	1.2
Verbal and Numeric Reasoning (VNR)	0.5	1.2	3.3	1.8	0.0	-0.6
Breast Cancer	0.5	1.2	2.9	0.6	-1.7	-0.6
Prostate Cancer	0.5	0.7	1.1	1.1	-0.1	-1.0
Coronary Artery Disease (CAD)	0.5	0.6	1.8	0.2	-0.1	1.3
Neuroticism (2016)	0.5	0.7	1.0	1.0	-0.5	-1.0
Age when periods started (menarche)	0.5	1.3	2.7	-0.2	-1.6	-1.0
Tinnitus: Yes, but not now, but have in the past	0.5	0.6	1.4	1.2	-0.6	-0.3
Medication: Atenolol	0.5	0.6	1.2	-0.8	-1.1	-0.1
Chronic bronchitis/emphysema (father)	0.5	0.6	1.5	-0.1	0.5	1.2
Financial difficulties in last 2 years	0.5	0.7	1.5	-1.2	-0.8	-0.2
Impedance of arm (right)	0.5	2.4	6.9	2.6	-0.3	0.5
Noisy workplace	0.5	0.6	1.3	-0.4	-0.6	1.1
Tense / ‘highly strung’	0.5	0.8	1.6	0.7	1.3	0.5
Comparative body size at age 10	0.5	1.4	3.0	-0.5	-1.7	-0.9
Migraine (self-reported)	0.5	0.7	1.6	-1.3	0.6	-0.3
Medication: Ibuprofen	0.5	0.6	1.2	-1.1	-0.8	-0.3
Alcohol intake frequency.	0.5	1.3	2.0	-1.4	-1.3	-0.3
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.7	1.3	1.1	0.2	-0.8
Medication: Aspirin	0.5	0.6	0.9	-0.1	1.0	0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.1	2.0	-1.1	-0.3	1.4
Commuting to job workplace: Public transport	0.5	0.6	1.5	-0.1	1.2	0.5
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.1	0.7	-1.0	-0.2
Neuroticism (Nagel 2018)	0.4	0.8	1.3	0.8	1.2	0.8
Irritable Bowel Disease (IBD)	0.4	0.9	1.6	-0.7	-0.7	-1.3
Hand grip strength (left)	0.4	1.0	2.6	-1.6	-0.1	0.5
Hearing difficulty/problems: Yes	0.4	0.7	1.4	0.3	1.2	0.7
Fed-up feelings	0.4	0.7	1.7	-1.3	0.6	0.2
Mouth/teeth dental problems	0.4	0.5	1.4	1.2	0.0	-0.5
Prospective memory result	0.4	0.5	1.0	-0.6	0.2	1.0
Pulse wave Arterial Stiffness index	0.4	0.4	1.2	0.1	1.1	0.3
Peak expiratory flow (PEF)	0.4	0.9	2.3	-0.5	0.4	1.5
Medication: Paracetamol	0.4	0.7	1.9	0.0	0.4	-1.4
Glaucoma (self-reported)	0.4	0.5	1.3	0.3	-1.2	0.3
Medication: Amlodipine	0.4	0.6	0.8	-0.9	0.5	0.7
Medication: Ventolin 100micrograms inhaler	0.4	0.5	0.7	-0.3	0.8	0.8
Forced vital capacity (FVC), Best measure	0.4	1.3	2.7	-0.5	1.0	1.6
Number of children fathered	0.4	0.4	0.9	0.3	0.5	1.0
Pulse wave peak to peak time	0.4	0.4	1.2	0.2	-1.1	-0.3
Medication: Omeprazole	0.4	0.5	1.0	-0.7	0.3	1.0
Had major operations	0.4	0.4	1.3	0.1	1.1	0.1
Ever had bowel cancer screening	0.4	0.4	1.0	-0.5	0.0	-1.0
Miserableness	0.4	0.6	1.0	-0.7	0.7	1.0
Medication: Blood pressure	0.4	0.7	1.6	0.6	-1.3	-0.1
Medication: Bendroflumethiazide	0.4	0.6	1.0	-0.8	0.3	1.0
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	0.7	-0.4	0.8	0.7
Supplements: Calcium	0.4	0.4	1.1	-0.4	0.0	-1.1
Depressed Affect (Nagel 2018)	0.3	0.7	1.1	0.2	1.1	0.9
Intelligence (Savage-Jansen 2018)	0.3	0.8	1.1	1.1	-0.5	-1.0
Crohns Disease (2017)	0.3	0.7	1.7	1.3	-0.6	-0.3
Ovarian Cancer	0.3	0.4	0.6	0.6	0.8	0.2
Waist Hip Ratio (WHR)	0.3	1.3	2.4	1.1	-0.7	1.6
Respiratory disease	0.3	0.6	1.7	-0.4	-0.3	1.3
Supplements: Zinc	0.3	0.3	0.4	-0.4	0.6	0.6
Stomach or abdominal pain in last month	0.3	0.4	0.8	0.9	-0.4	0.3
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	1.1	0.6	1.0	0.0
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.3	-0.3	-0.1	1.1
Illnesses of mother	0.3	0.4	1.0	1.0	-0.1	0.4
Gout (self-reported)	0.3	0.4	0.6	-0.4	0.8	-0.5
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.1	-1.1	0.1	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	0.5	0.7	-0.5	-0.6
Wheeze or whistling in the chest in last year	0.3	0.6	0.9	-0.9	-0.1	0.9
Qualifications: College or University degree	0.3	1.1	1.6	1.3	0.6	-1.1
Medication: Allopurinol	0.3	0.4	0.8	0.0	0.9	0.7
Heart disease (mother)	0.3	0.4	0.7	-0.8	0.2	-0.6
Pulse rate, automated reading	0.3	1.1	2.3	-0.6	1.5	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	1.7	-1.3	0.1	0.5
Handedness (chirality/laterality): Left-handed	0.3	0.3	0.7	-0.2	-0.9	0.5
Mood swings	0.3	0.5	0.7	-0.4	0.8	0.8
Loneliness, isolation	0.3	0.4	0.9	0.5	0.0	-0.9
Mineral and other dietary supplements	0.3	0.3	0.7	0.9	0.4	0.4
Asthma (self-reported)	0.3	0.5	1.6	0.3	-0.1	1.2
Hearing aid user	0.3	0.4	0.6	0.8	-0.3	-0.7
Medication: Lisinopril	0.3	0.4	0.7	0.9	-0.4	0.5
Commuting to job workplace: Cycle	0.3	0.3	0.9	-0.9	0.3	0.1
Crohns Disease (2012)	0.2	0.3	0.4	0.6	-0.6	0.0
Rheumatoid Arthritis	0.2	0.3	0.6	-0.1	-0.8	-0.4
Blood Eosinophil Count	0.2	1.9	5.5	0.2	-0.3	2.3
Height	0.2	2.9	4.0	2.0	1.7	1.4
Cardiovascular Disease	0.2	0.6	1.0	-1.0	0.9	0.1
Neuroticism	0.2	0.4	0.9	0.5	1.0	0.4
Tanning	0.2	2.0	4.7	-0.7	-0.8	-2.2
Sitting height	0.2	1.2	1.8	-0.3	1.3	1.3
Nervous feelings	0.2	0.3	0.6	0.2	-0.6	-0.8
Hearing difficulty/problems with background noise	0.2	0.3	0.9	1.0	0.0	0.2
Hair/balding pattern: Pattern 2	0.2	0.2	0.5	0.7	0.1	0.4
Forced vital capacity (FVC)	0.2	0.6	1.3	-0.3	0.7	1.1
Number of live births	0.2	0.3	0.5	0.5	-0.7	0.0
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	1.1	-0.9	0.7	1.0
Mouth/teeth dental problems: Dentures	0.2	0.4	0.9	-0.4	-1.0	-0.3
Asthma	0.2	0.4	1.0	0.4	-0.1	1.0
Loud music exposure frequency	0.2	0.2	0.3	0.2	0.6	0.5
Blood clot in the leg (DVT)	0.2	0.2	0.5	-0.1	-0.4	-0.7
Headache pain in last month	0.2	0.3	0.5	-0.7	0.2	0.6
Shortness of breath walking on level ground	0.2	0.2	0.4	-0.0	-0.5	0.6
Neck or shoulder pain in last month	0.2	0.2	0.6	-0.0	-0.8	-0.2
Comparative height size at age 10	0.2	1.2	1.9	1.4	1.0	0.9
Suffer from ‘nerves’	0.2	0.4	1.1	0.2	0.2	-1.0
Overall health rating	0.2	0.4	1.0	-1.0	-0.3	-0.1
Chest pain or discomfort	0.2	0.3	0.7	-0.8	-0.5	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.3	-0.5	-0.6	0.0
Long-standing illness, disability or infirmity	0.2	0.3	0.7	-0.2	0.9	-0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.3	0.7	0.3	-0.8	-0.1
Medication for cholesterol	0.2	0.3	0.8	0.3	0.9	-0.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	0.8	0.3	-0.9	0.2
Guilty feelings	0.2	0.3	0.6	0.7	-0.4	0.4
Mother’s age at death	0.2	0.2	0.7	0.8	0.1	0.2
High cholesterol (Self-reported)	0.2	0.4	0.7	-0.7	0.0	0.8
Fractured/broken bones in last 5 years	0.2	0.3	0.8	0.9	0.0	-0.4
Unable to work because of sickness or disability	0.2	0.3	0.6	-0.8	0.2	0.4
Basal cell carcinoma (self-reported)	0.2	0.3	0.7	-0.8	0.1	0.4
Alcohol drinker status: Previous	0.2	0.2	0.6	-0.1	-0.4	-0.7
Schizophrenia vs Biploar Disorder	0.1	0.1	0.2	-0.0	-0.5	-0.2
Worry (Nagel 2018)	0.1	0.2	0.4	0.5	0.7	-0.1
Alzheimer’s Disease (in mother)	0.1	0.1	0.4	0.0	0.2	-0.6
HbA1C	0.1	0.2	0.3	-0.2	0.4	-0.6
Blood Red Count	0.1	0.8	1.1	-1.0	-1.0	0.7
Blood White Count	0.1	0.8	1.9	-1.4	-0.1	0.7
Heel T-Score	0.1	0.7	1.4	0.3	1.2	0.7
Systolic Blood Pressure	0.1	0.6	0.8	-0.6	0.9	0.7
Lung FVC	0.1	0.6	1.2	-0.2	0.7	1.1
Hair Pigment	0.1	1.8	3.6	-1.9	-1.0	-0.9
Average weekly spirits intake	0.1	0.1	0.3	0.6	0.3	-0.0
Ever had hysterectomy (womb removed)	0.1	0.1	0.2	-0.3	0.1	0.4
Current tobacco smoking	0.1	0.1	0.3	-0.1	-0.1	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.2	-0.4	-0.4	-0.0
Relative age voice broke	0.1	0.1	0.3	-0.3	-0.2	-0.5
High blood pressure (mother)	0.1	0.2	0.3	-0.3	-0.5	-0.5
Number of incorrect matches in round	0.1	0.2	0.5	-0.7	0.1	0.4
Pain all over the body in last month	0.1	0.1	0.1	-0.4	0.1	-0.2
Medication: Ramipril	0.1	0.2	0.4	0.4	0.6	0.1
Neuroticism score	0.1	0.3	0.5	-0.7	0.5	0.2
Father’s age at death	0.1	0.2	0.4	-0.6	0.3	0.1
Worrier / anxious feelings	0.1	0.2	0.5	-0.3	-0.7	-0.2
Hair/balding pattern: Pattern 3	0.1	0.2	0.4	-0.3	0.3	0.6
Pulse rate	0.1	0.2	0.3	0.6	-0.5	0.3
Ever highly irritable/argumentative for 2 days	0.1	0.2	0.3	0.4	-0.1	0.6
Birth weight	0.1	0.1	0.2	0.4	0.4	0.0
Health satisfaction	0.1	0.1	0.3	0.0	-0.3	-0.6
Medication for pain relief, constipation, heartburn	0.1	0.2	0.3	0.3	0.4	0.5
Number of full sisters	0.1	0.1	0.2	-0.4	-0.3	0.4
Family relationship satisfaction	0.1	0.1	0.2	-0.1	0.5	-0.0
Illnesses of father: Heart disease	0.1	0.1	0.2	-0.3	0.4	-0.1
Illnesses of siblings: Diabetes	0.1	0.2	0.4	-0.6	-0.3	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.2	0.3	-0.4	0.5
Smoking status: Current	0.1	0.1	0.3	-0.0	0.0	-0.5
Eye problems/disorders: Glaucoma	0.1	0.2	0.4	0.6	-0.4	0.1
Vascular/heart problems diagnosed by doctor	0.1	0.3	0.6	0.7	-0.5	0.1
Cholesterol lowering medication	0.1	0.1	0.3	0.1	-0.3	0.6
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.2	-0.3	-0.1	-0.4
Heart disease (siblings)	0.1	0.1	0.2	0.4	-0.5	-0.0
Alzheimer’s Disease (including proxy)	0.0	0.0	0.1	0.0	-0.0	-0.3
Blood Platelet Count	0.0	0.4	1.2	0.1	-0.0	1.1
Smoking Status	0.0	0.1	0.2	0.3	0.3	0.4
Taking other prescription medications	0.0	0.1	0.1	0.0	0.3	-0.3
High blood pressure	0.0	0.1	0.3	0.1	0.5	-0.0
Happiness	0.0	0.1	0.1	0.3	-0.3	-0.1
Standing height	0.0	0.4	0.5	0.7	0.5	0.7
Worry too long after embarrassment	0.0	0.1	0.1	0.3	0.0	0.2
Medication: Aspirin	0.0	0.1	0.1	-0.3	0.3	0.0
Hypertension (Self-reported)	0.0	0.1	0.2	0.2	0.5	-0.3
Financial situation satisfaction	0.0	0.0	0.1	-0.3	-0.2	-0.1
Average weekly beer plus cider intake	0.0	0.0	0.1	0.0	-0.2	-0.2

Hub : Genes

MYH15

Models

Trait associations