Hub : Genes

IFT57

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1500	0.0340	6.7e-12	0.134	0.105	0.120	0.122	0.128	5.1e-16	1e-12	2.3e-14	1.3e-14	2.6e-15
2	GTEx	Adrenal Gland	0.2132	0.0732	7.8e-04	0.104	NA	0.085	NA	0.112	1.5e-04	NA	5.7e-04	NA	8.2e-05
3	GTEx	Brain Cortex	0.2170	0.0790	3.7e-03	0.031	NA	0.126	NA	0.132	4.8e-02	NA	2.4e-04	NA	1.7e-04
4	GTEx	Cells Transformed fibroblasts	0.1200	0.0460	2.9e-03	0.031	NA	0.035	NA	0.030	2.1e-03	NA	1.1e-03	NA	2.4e-03
5	GTEx	Colon Transverse	0.1430	0.0470	8.0e-05	0.108	NA	0.157	NA	0.155	8.0e-06	NA	6.1e-08	NA	7.7e-08
6	GTEx	Lung	0.1251	0.0412	1.4e-04	0.020	NA	0.033	NA	0.028	1.0e-02	NA	1.5e-03	NA	3.1e-03
7	GTEx	Pancreas	0.2390	0.0740	1.5e-04	0.100	NA	0.119	NA	0.111	5.5e-05	NA	1.0e-05	NA	2.2e-05
8	GTEx	Skin Not Sun Exposed Suprapubic	0.1800	0.0670	1.9e-03	-0.005	NA	0.007	NA	-0.005	7.8e-01	NA	1.3e-01	NA	7.6e-01
9	GTEx	Skin Sun Exposed Lower leg	0.1050	0.0400	8.0e-04	0.088	NA	0.058	NA	0.060	9.5e-08	NA	1.5e-05	NA	9.8e-06
10	NTR	Blood	0.0249	0.0088	1.6e-04	0.000	0.009	0.006	0.009	0.002	2.2e-01	4e-04	3.2e-03	5.4e-04	7.1e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Bipolar Disorder (2018)	3.8	6.0	14.2	-2.6	-2.4	-0.4	-0.3	-2.4	-1.0	-2.9	-2.4	-3.8	-3.5
Bipolar Disorder or Schizophrenia	4.1	9.9	21.7	-3.9	-3.6	-1.5	-0.8	-1.8	1.1	-4.6	-2.6	-3.7	-4.7
Depressed Affect (Nagel 2018)	2.0	4.3	12.3	2.0	1.7	-0.8	-3.5	-0.3	-2.4	3.0	0.2	-1.6	2.3
Depression (Nagel 2018)	1.1	1.6	6.7	0.4	0.0	-0.7	-2.6	-1.5	-1.4	0.6	-0.4	-1.9	-0.8
Intelligence (Savage-Jansen 2018)	1.8	5.4	22.4	0.1	-0.2	1.9	-1.9	4.7	0.5	0.2	-3.4	-1.9	3.0
Neuroticism (Nagel 2018)	1.5	3.4	9.5	1.6	1.3	-1.2	-3.1	0.5	-1.9	2.7	-0.5	-1.6	2.2
Schizophrenia (2018)	2.5	5.2	12.6	-2.9	-2.7	-1.7	-0.8	-0.4	2.2	-3.5	-1.5	-1.7	-3.1
Schizophrenia vs Biploar Disorder	1.6	2.1	8.0	-1.1	-1.6	-1.4	-1.2	1.5	2.8	-1.2	-0.7	1.3	-0.7
Worry (Nagel 2018)	0.8	1.7	4.6	1.6	1.4	-0.4	-1.7	0.5	-0.9	1.9	-0.4	-0.5	2.1
Alzheimer’s Disease (in mother)	0.8	1.0	5.4	-0.2	-0.3	0.5	-0.4	2.3	1.5	-1.1	-0.3	-0.5	0.5
Alzheimer’s Disease (in father)	0.9	1.0	2.7	0.9	0.9	0.4	1.1	-1.6	-1.4	0.4	1.3	0.1	-0.7
Alzheimer’s Disease (including proxy)	0.2	0.3	0.8	0.8	0.7	-0.1	0.1	0.2	-0.5	-0.0	0.9	0.3	0.3
Crohns Disease (2017)	0.5	1.2	5.1	0.2	0.4	1.3	-0.0	-1.6	-2.2	0.6	-1.3	-0.1	0.4
Irritable Bowel Disease (IBD)	0.4	1.1	2.9	0.6	0.8	1.0	0.5	-1.7	-1.4	0.6	-0.2	1.5	0.9
Ulcerative Colitis (UC)	0.6	1.1	3.1	1.1	1.2	0.3	0.2	-1.5	-0.8	0.8	0.8	1.8	1.1
Major Depression (MDD)	1.3	1.6	6.0	-1.5	-1.4	-0.6	-1.0	0.3	0.9	-0.8	-0.2	-2.4	-1.7
Reaction Time	2.4	4.5	20.5	0.4	0.5	0.7	-1.0	3.4	2.2	0.3	-2.4	-4.5	0.1
Verbal and Numeric Reasoning (VNR)	1.8	4.4	18.1	0.5	0.0	1.4	-2.6	4.3	0.1	0.6	-1.8	-2.4	2.8
Breast Cancer	0.2	0.5	1.8	-0.0	-0.1	-0.4	1.4	-1.0	-0.4	-0.7	-0.6	1.0	0.5
Ovarian Cancer	0.6	0.8	4.2	-0.0	0.2	0.4	0.9	2.0	0.0	0.7	1.1	-1.0	0.3
Prostate Cancer	0.5	0.6	3.2	-0.0	0.3	-0.3	1.4	-0.1	-1.8	0.6	-0.6	-0.1	-0.6
Age at First Birth	1.0	1.4	4.2	-2.1	-1.5	-1.0	0.4	1.0	-0.2	-1.5	-1.2	-0.9	-1.2
Bipolar Disorder (2011)	1.8	1.7	5.1	-0.4	-0.3	2.2	-1.2	-1.0	-0.5	0.1	-1.9	-2.2	-0.9
Body Mass Index (BMI) (2010)	1.1	1.5	5.9	1.2	1.1	0.0	-1.9	-2.4	-0.5	1.0	-0.3	-0.8	-0.8
Coronary Artery Disease (CAD)	0.9	1.0	4.6	-0.2	-0.5	-1.0	-1.4	-2.1	-0.7	0.1	0.9	-0.9	-0.8
Crohns Disease (2012)	0.5	0.8	2.3	0.6	0.8	1.4	-0.1	-0.8	-1.5	0.5	-1.4	-0.4	0.4
Mean Putamen Volume	1.3	1.4	4.0	1.4	1.2	2.0	0.1	0.9	0.3	1.2	-0.2	0.9	1.9
Fasting Glucose	0.6	0.8	3.6	-0.4	-0.0	0.3	-0.3	-0.1	-0.9	-0.5	-1.4	-1.9	-0.8
HbA1C	0.5	0.6	1.7	1.0	0.5	1.3	0.3	-1.1	-0.4	0.5	-0.1	-0.3	1.1
HDL Cholesterol	1.1	1.8	4.2	-2.0	-1.7	-1.8	0.6	1.4	1.1	-1.7	-0.7	0.9	-0.3
LDL Cholesterol	0.6	1.0	4.1	1.0	0.8	0.2	-0.4	-2.0	-0.2	0.8	1.5	1.1	-0.4
Lupus	0.3	0.4	2.6	0.2	0.3	0.5	0.6	1.6	0.3	-0.1	-0.0	-0.6	-0.3
Neuroticism (2016)	1.0	1.4	4.8	0.9	0.9	1.4	-0.3	1.7	0.2	1.2	0.8	0.5	2.2
Primary Biliary Cirrhosis	0.5	0.7	3.9	0.5	0.5	-0.2	0.5	-2.0	-0.0	0.2	1.3	0.2	-0.7
Rheumatoid Arthritis	0.4	0.6	2.1	0.4	0.1	-0.6	-0.1	1.4	-0.2	0.8	0.5	1.1	1.2
Schizophrenia (2014)	2.9	6.3	12.7	-3.3	-3.1	-1.6	-1.5	0.1	2.1	-3.6	-2.8	-2.0	-3.1
Triglycerides	0.5	0.9	2.8	1.1	1.1	1.7	-0.1	-0.5	0.0	0.7	0.8	-1.4	-0.2
Type 2 Diabetes (T2D) (2012)	0.6	0.7	1.5	-0.5	-0.6	0.2	0.3	-1.2	0.9	-0.6	-1.2	-0.8	-1.0
Ulcerative Colitis	0.3	0.4	1.4	0.7	0.7	0.4	-0.2	-0.5	-0.5	0.6	0.1	1.0	1.2
Blood Eosinophil Count	0.3	2.4	5.8	-0.5	-0.8	1.1	-1.8	-2.4	-1.3	-0.9	-2.2	-1.9	-1.4
Blood Platelet Count	0.7	8.1	30.6	-1.3	-1.7	4.8	-1.5	2.6	2.6	-2.0	-5.5	-1.4	0.8
Blood Red Count	0.1	1.0	2.2	1.1	0.9	1.2	-0.2	-0.6	-1.5	1.1	1.4	-0.4	0.7
Blood White Count	0.3	2.0	12.0	-0.2	-0.6	3.5	0.2	-0.9	0.1	-0.7	-2.2	-1.1	-0.5
Heel T-Score	0.2	1.5	6.4	0.7	0.9	2.5	1.1	0.4	-1.0	1.3	0.9	-1.3	0.7
BMI	2.7	15.5	39.3	4.7	4.5	-1.2	-3.1	-6.3	-4.5	4.4	3.2	-2.8	-1.8
Height	0.1	2.2	6.8	-0.5	-0.7	2.5	-1.5	1.2	0.2	-1.4	1.2	-2.6	-0.2
Waist Hip Ratio (WHR)	0.3	1.4	4.1	-0.4	-0.4	2.0	0.2	-0.3	1.9	-1.9	0.9	-1.4	-0.2
Systolic Blood Pressure	0.3	1.4	4.7	-0.6	-0.7	1.1	1.8	1.7	2.2	-1.0	-0.6	0.1	0.5
Smoking Status	2.0	4.9	19.7	-1.2	-0.9	-1.1	1.3	-4.4	-0.8	-2.5	1.2	0.5	-3.9
Allergy or Eczema	1.4	3.6	15.6	-0.8	-0.9	-0.3	-3.3	2.4	0.6	-0.7	-1.5	-3.9	-0.2
Cardiovascular Disease	0.6	1.8	4.8	2.2	2.2	-0.7	-0.6	-0.5	-0.7	1.9	0.5	-1.0	1.5
Hypothyroidism (self reported)	1.3	3.1	9.4	1.4	1.1	-0.2	0.5	-0.2	0.4	1.3	3.1	2.5	3.1
Respiratory disease	0.3	0.7	3.3	0.3	-0.3	-0.4	-1.8	-1.3	-0.2	-0.2	-1.2	-0.4	-0.0
Type 2 Diabetes (T2D) (2018)	1.2	2.3	3.5	1.7	1.9	-0.3	-1.3	-1.6	-1.8	1.2	1.8	-1.8	-1.1
Lung FEV1/FVC ratio	0.3	1.4	7.3	0.0	0.1	-0.0	0.1	-2.7	-2.3	0.4	-0.9	0.9	0.2
Lung FVC	0.5	2.7	8.5	-1.7	-1.4	-0.6	0.5	0.2	1.7	-2.4	2.9	-0.4	-2.1
Neuroticism	1.1	2.7	5.7	1.7	1.7	-1.3	-1.9	-0.0	-2.3	2.4	0.2	-1.2	1.9
Chronotype (morning person)	1.5	3.4	9.5	1.6	1.3	2.0	0.5	-0.5	-0.9	2.2	-2.4	2.1	3.1
Hair Pigment	0.1	2.0	9.6	-0.9	-1.1	0.3	0.9	2.2	3.1	-1.2	-0.0	-0.3	1.1
Tanning	0.1	1.2	7.1	-0.2	-0.5	-0.9	0.0	-2.7	-1.5	-0.2	0.6	1.2	-0.1
Hand grip strength (left)	1.3	3.3	8.1	-1.6	-1.7	0.1	-0.1	-1.7	1.7	-2.6	2.8	0.9	-2.6
Number of treatments/medications taken	1.5	2.6	7.0	2.2	1.9	1.1	-0.4	-2.7	-1.4	1.9	1.5	0.6	1.0
Average weekly spirits intake	0.3	0.4	1.2	0.9	0.8	-0.3	-0.4	-0.8	-0.3	0.5	1.1	0.3	-0.3
Sensitivity / hurt feelings	1.3	2.2	5.0	1.6	1.2	0.3	-2.2	0.3	-1.7	2.2	-0.4	-0.8	2.2
Frequency of depressed mood in last 2 weeks	1.1	1.6	4.8	0.9	0.9	-0.1	-1.0	-2.0	-2.2	1.1	1.1	-0.9	-1.0
Hearing difficulty/problems: Yes	0.2	0.3	1.9	-0.1	0.1	0.2	-0.4	0.5	-0.7	0.2	0.1	-1.4	-0.1
Relative age of first facial hair	1.9	3.9	7.9	-2.8	-2.6	-2.0	0.7	1.4	2.5	-2.8	-1.4	0.9	-1.2
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	3.4	-1.4	-1.8	-0.8	-0.2	-0.9	0.7	-1.5	-0.3	0.4	-0.6
Ever used hormone-replacement therapy (HRT)	0.3	0.4	2.0	0.0	0.3	-0.1	1.4	0.7	0.8	-0.3	0.1	-0.5	0.2
Ever had hysterectomy (womb removed)	0.7	0.8	4.0	-0.4	0.0	-0.3	2.0	-0.4	0.5	-0.6	1.2	0.4	-1.3
Systolic blood pressure, automated reading	0.5	1.3	3.5	1.5	1.0	1.9	-0.9	0.8	1.0	1.0	-0.6	-0.9	1.4
Eye problems/disorders: Diabetes related eye disease	1.5	1.7	3.6	-1.1	-0.6	-1.8	1.5	-0.3	-1.1	-1.6	-1.2	-1.0	-1.9
Angina	1.3	1.7	5.2	1.9	1.7	0.8	-0.4	-2.3	-1.1	1.0	1.2	0.2	-0.6
Medication for hormone replacement therapy	0.6	0.6	2.2	-0.2	-0.2	0.4	0.1	0.8	1.3	-0.3	-1.5	-0.7	1.0
Vitamin and mineral supplements	1.2	1.7	4.8	0.6	0.8	0.5	-1.4	1.9	-0.1	0.6	-2.2	-1.8	1.4
Supplements: Zinc	0.5	0.5	1.9	-0.4	-0.4	1.0	-0.1	-1.4	0.7	-0.9	0.3	0.0	-0.8
Medication: Co-codamol	1.0	1.1	3.6	1.1	1.1	0.2	0.5	-1.2	0.0	1.2	1.9	1.4	0.1
Medication: Metformin	0.8	1.2	3.5	0.8	1.0	-0.7	0.1	-1.9	-1.8	1.0	1.0	-0.7	-0.5
Diabetes (father)	0.9	1.1	4.2	0.8	0.4	-0.5	-2.1	-1.7	-0.7	1.3	-0.6	-0.6	0.7
Diabetes (mother)	1.0	1.2	4.3	1.3	1.2	-0.2	-2.1	-1.1	-0.9	1.2	0.5	-1.0	0.0
Severe depression (siblings)	0.7	0.8	4.2	0.5	0.2	0.3	-2.1	-0.3	-0.3	0.6	-0.9	-0.9	0.9
Pack years adult smoking proportion	2.8	4.2	14.6	-0.9	-1.0	-0.9	0.9	-3.5	1.2	-1.3	2.5	3.8	-1.7
Impedance of leg (right)	1.7	8.1	14.5	-3.6	-3.6	1.3	2.0	3.7	3.8	-3.8	-2.4	1.1	0.4
Leg fat-free mass (left)	1.7	9.2	19.7	3.5	3.4	-0.7	-2.0	-4.0	-4.4	3.7	3.0	-2.0	-1.1
Trunk fat percentage	2.0	7.9	17.6	3.2	3.1	0.1	-2.4	-3.1	-4.1	3.0	0.1	-4.2	-1.1
Hand grip strength (right)	1.6	4.5	11.2	-2.4	-2.2	-1.0	-0.5	-0.9	2.4	-3.2	2.2	-0.2	-3.3
Townsend deprivation index at recruitment	1.6	2.2	8.9	-1.5	-1.1	-0.8	0.7	-1.1	0.6	-2.0	-1.7	-0.4	-3.0
Current tobacco smoking	2.4	4.0	11.4	-1.6	-1.2	-1.8	1.2	-3.0	0.5	-2.8	1.0	1.3	-3.4
Average weekly fortified wine intake	1.7	2.0	7.0	-0.9	-0.8	0.7	-0.6	1.8	0.0	-0.7	-2.6	-2.5	-0.1
Maternal smoking around birth	0.6	0.9	2.6	1.4	1.2	0.2	-1.6	-0.8	-0.4	1.4	0.5	-0.2	0.6
Fed-up feelings	0.9	1.6	4.6	1.6	1.4	-0.3	-1.5	-1.0	-1.4	2.1	0.1	-0.1	1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	4.3	0.2	0.1	-1.1	-0.8	-2.1	-0.6	0.5	0.1	0.4	-0.4
Relative age voice broke	1.3	2.0	6.8	-1.1	-1.2	-0.7	-0.3	2.0	2.6	-1.8	-0.4	1.4	-0.4
Taking other prescription medications	0.8	1.3	5.7	1.0	0.9	0.2	0.2	-2.4	-1.8	1.1	0.6	0.5	0.3
Age when periods started (menarche)	0.5	1.3	4.5	-0.7	-0.3	-0.1	2.1	-0.5	0.1	-0.8	1.7	1.7	-1.1
Bilateral oophorectomy (both ovaries removed)	1.6	1.9	3.7	-1.9	-1.7	-1.2	0.8	1.7	1.8	-1.6	-1.0	-0.6	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	6.6	0.3	0.8	-0.1	0.4	0.2	-1.4	1.3	0.2	-2.6	-0.8
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.1	-0.4	-0.4	-0.2	0.5	1.0	0.5	0.2	-0.7	-1.1	-0.2
Qualifications: CSEs or equivalent	1.4	1.8	8.4	1.1	0.5	0.4	-0.9	-2.9	0.0	1.5	1.0	1.9	-0.5
Serious illness, injury or assault to yourself	0.3	0.4	1.4	0.2	0.5	-0.4	0.3	-0.3	-0.4	0.4	-0.4	-1.2	-1.1
High blood pressure	0.7	2.0	5.0	2.2	2.2	0.3	-0.6	-0.0	-0.7	1.7	1.0	-0.6	2.1
Hayfever, allergic rhinitis or eczema	1.5	3.3	12.7	-1.0	-0.9	-0.6	-2.8	2.3	0.4	-0.5	-2.1	-3.6	0.2
Multivitamins +/- minerals	1.2	1.5	5.9	-0.8	-1.1	-0.9	0.5	-2.1	0.1	-0.9	2.4	0.5	-1.2
Stomach or abdominal pain in last month	0.2	0.3	1.3	0.4	0.5	0.0	1.2	-0.6	-0.8	-0.2	0.2	-0.3	-0.4
Supplements: Glucosamine	2.3	3.0	8.5	0.7	0.9	-1.4	2.2	-2.0	-1.0	0.8	2.9	2.0	-1.7
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	2.9	1.3	1.2	1.3	-0.7	-0.3	-0.8	1.2	-0.6	-1.7	1.1
Medication: Atenolol	1.7	2.1	5.9	2.3	2.4	1.5	0.7	-1.8	-1.7	1.1	0.3	-0.1	0.6
Medication: Levothyroxine sodium	1.7	2.9	8.9	1.4	1.2	0.8	1.6	-1.1	-0.0	1.2	3.0	2.9	1.5
Sitting height	0.1	0.8	2.6	0.0	-0.0	1.6	-0.7	-1.1	-0.8	0.0	0.2	-1.6	-0.7
Chronic bronchitis/emphysema (father)	0.9	1.1	2.5	-1.0	-1.3	-1.4	-0.6	-0.5	0.8	-1.1	-1.0	-1.6	-0.4
High blood pressure (mother)	1.0	1.4	5.5	1.1	1.1	1.0	0.5	-0.4	-1.2	1.3	-2.3	0.1	1.1
Body mass index (BMI)	3.4	14.5	28.5	5.0	5.1	-0.4	-1.5	-5.0	-5.3	5.0	2.2	-2.7	-0.9
Impedance of leg (left)	1.5	7.0	14.8	-3.3	-3.3	1.5	1.4	3.4	3.4	-3.9	-2.3	0.6	0.3
Leg predicted mass (left)	1.7	9.2	19.9	3.5	3.5	-0.6	-1.9	-4.0	-4.5	3.7	2.9	-2.1	-1.1
Trunk fat mass	2.4	10.4	21.3	3.8	3.6	0.2	-2.7	-3.9	-4.6	3.5	1.1	-4.2	-1.3
Waist circumference	3.3	12.0	23.9	4.8	4.9	0.5	-1.7	-4.0	-4.4	4.3	1.9	-3.5	-0.4
Number of incorrect matches in round	0.6	1.0	3.6	-0.9	-0.8	0.1	0.9	-1.0	0.7	-1.9	1.1	0.2	-1.3
Past tobacco smoking	1.1	2.1	11.0	1.0	0.7	0.7	-0.4	1.8	0.4	1.0	-1.0	1.6	3.3
Alcohol usually taken with meals	0.3	0.5	1.9	-0.5	-0.1	-0.4	0.6	1.4	-1.1	0.5	0.6	-0.3	-0.5
Nervous feelings	0.2	0.4	1.4	0.2	-0.2	-0.2	-1.2	0.6	0.1	0.1	-1.0	-0.0	0.8
Frequency of tenseness / restlessness in last 2 weeks	1.0	1.5	3.8	1.7	1.7	-0.4	-0.5	-0.8	-1.9	1.6	1.2	-0.2	0.7
Hearing difficulty/problems with background noise	0.4	0.6	3.1	-0.5	-0.3	-0.1	-0.1	1.8	-0.3	-0.6	-0.2	-1.3	0.1
Hair/balding pattern: Pattern 2	0.5	0.7	2.6	0.7	0.7	1.6	-0.1	-0.5	-0.7	1.2	0.1	-0.4	0.6
Had menopause	0.5	0.6	2.3	0.2	0.4	0.2	0.8	1.5	1.1	0.6	0.4	-0.2	0.9
Had other major operations	2.5	3.0	8.5	2.2	2.3	0.2	0.3	0.0	-2.8	2.9	0.0	-0.3	1.8
Forced vital capacity (FVC)	0.6	2.4	6.2	-2.1	-2.0	-0.6	-1.0	0.9	1.8	-2.5	0.8	-1.0	-1.5
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	4.3	-0.0	0.4	-0.1	0.6	-0.1	-1.0	0.9	0.3	-2.1	-0.6
Ever unenthusiastic/disinterested for a whole week	0.6	0.8	3.2	-0.2	0.1	-1.1	-0.6	0.3	-0.2	0.4	1.8	-0.8	-1.3
Qualifications: None of the above	2.4	5.1	28.3	0.3	0.2	-1.0	1.6	-5.3	-0.4	-0.6	2.5	3.2	-1.3
Financial difficulties in last 2 years	0.5	0.6	1.9	0.8	0.8	1.1	0.8	-1.4	-0.9	0.3	-0.5	0.2	-0.1
Mouth/teeth dental problems	0.8	1.3	3.8	-1.4	-1.1	0.6	1.1	2.0	1.4	-1.3	0.9	0.4	-0.0
Heart attack	0.6	0.7	3.2	0.3	0.1	0.6	-1.1	-1.8	-1.2	-0.6	0.2	-0.7	-0.2
Allergy	0.7	1.5	6.5	0.2	0.3	0.5	2.5	-1.1	0.5	-0.0	1.1	2.4	-0.5
Pain all over the body in last month	0.5	0.5	2.0	0.3	0.2	-1.4	-0.6	-1.2	-0.7	0.6	-0.5	-0.0	0.3
Diabetes (self-reported)	0.7	1.1	2.0	0.7	0.7	-0.4	-1.3	-1.2	-1.4	-0.0	1.3	-1.3	-1.3
Hayfever/allergic rhinitis (self-reported)	1.6	2.1	12.7	-0.5	-0.7	-0.5	-1.0	1.6	0.2	-0.5	-3.6	-0.8	1.5
Medication: Ramipril	0.9	1.2	6.0	0.8	1.0	0.2	1.2	-0.8	-1.1	0.6	2.5	-0.5	-0.5
Medication: Simvastatin	0.6	0.9	2.8	0.4	0.6	-1.0	0.9	-1.7	-1.5	0.8	0.4	-0.1	-0.9
Fluid intelligence score	2.4	4.9	22.0	-1.0	-1.4	-0.3	-2.0	4.7	1.3	-1.1	-2.8	-2.0	2.3
Illnesses of siblings	1.3	1.8	4.4	-1.7	-1.6	-0.7	-0.0	0.2	0.4	-1.9	2.1	1.4	-1.3
Neuroticism score	1.5	3.2	7.6	2.2	2.0	-0.5	-1.7	-0.9	-2.8	2.8	0.7	-0.3	1.8
Weight	2.6	12.6	27.0	4.4	4.3	-0.1	-2.2	-4.6	-5.2	4.2	2.4	-3.1	-1.1
Impedance of arm (right)	1.1	5.2	13.9	-3.0	-3.0	0.7	0.1	3.0	1.7	-2.5	-3.7	-1.3	-0.0
Arm fat percentage (right)	3.2	12.6	27.4	4.4	4.5	0.1	-1.8	-4.4	-5.2	4.3	1.4	-3.8	-1.1
Trunk fat-free mass	0.9	5.4	12.5	2.6	2.6	0.2	-1.0	-3.2	-3.0	2.4	3.5	-0.7	-1.1
Hip circumference	3.0	12.8	29.0	5.0	5.1	0.1	-1.6	-3.4	-4.9	5.4	1.4	-2.7	-0.4
Time employed in main current job	0.8	0.9	8.1	-0.1	-0.0	0.1	-0.8	0.5	0.0	-0.4	0.4	-2.8	-0.3
Alcohol intake versus 10 years previously	1.1	1.7	4.8	2.0	1.6	0.9	-2.2	-1.0	-0.5	1.2	0.6	-1.2	0.8
Father’s age at death	1.2	1.6	3.4	-1.6	-1.5	-0.9	0.1	0.5	1.0	-1.7	-1.8	-0.9	-1.4
Worrier / anxious feelings	0.8	1.6	4.8	1.6	1.7	-0.4	0.8	0.5	-1.2	2.2	-0.0	0.1	1.7
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	2.8	1.4	0.7	0.0	-1.6	-1.7	-1.1	1.1	0.5	-0.5	0.7
Falls in the last year	0.7	1.0	4.2	-0.3	-0.4	-0.9	1.3	-1.4	0.1	-0.5	1.0	2.0	0.2
Hair/balding pattern: Pattern 3	0.4	0.5	1.1	-0.3	-0.3	-0.5	-0.8	0.8	1.1	-0.9	0.7	-1.1	0.1
Number of live births	0.6	0.9	3.4	0.1	0.2	-0.6	1.8	-1.1	-0.9	0.2	-1.5	-0.4	-0.7
Forced expiratory volume in 1-second (FEV1)	0.5	1.6	4.2	-1.9	-1.8	-0.6	-0.8	0.1	0.8	-2.0	0.9	-0.9	-1.4
Pulse rate	0.4	0.7	3.3	-0.6	-0.8	-1.8	0.1	0.9	0.2	-1.3	-0.3	-0.3	0.1
Happiness	1.8	2.2	8.1	-1.7	-1.4	-2.8	1.4	0.3	1.1	-1.6	0.3	0.5	-1.6
Noisy workplace	1.2	1.5	4.9	0.1	0.1	-0.9	-0.1	-2.2	-1.1	-0.3	2.0	0.7	-1.8
Qualifications: A levels/AS levels or equivalent	2.1	4.8	23.6	-1.5	-1.6	0.9	-0.5	4.9	1.8	-1.0	-2.4	-2.6	1.1
Serious illness, injury or assault of a close relative in last 2 years	1.6	1.8	4.7	1.8	1.7	0.1	-0.5	-1.8	-2.2	1.6	1.1	0.2	0.2
Mouth/teeth dental problems: Dentures	0.7	1.1	5.5	-0.1	-0.1	-0.8	0.5	-2.3	-1.7	0.1	-0.8	0.3	-1.0
Asthma	0.5	1.0	4.2	-0.3	-0.7	-1.2	-1.1	-2.1	-0.9	-0.4	-1.0	-0.1	-1.0
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.2	-0.7	-0.7	-1.1	1.1	-0.2	-0.8	-0.2	0.4	0.4	0.6
Medication: Cholesterol lowering	0.6	1.0	3.9	1.1	0.9	0.0	-2.0	-0.7	-1.0	1.4	-0.3	-0.5	0.4
Depression (self-reported)	0.5	0.6	1.8	-0.1	-0.2	-0.8	-1.4	0.3	-0.9	0.8	-0.3	-1.3	0.5
Medication: Lansoprazole	1.4	1.7	6.0	1.7	1.5	0.4	-0.3	0.2	-0.6	1.5	2.4	0.9	1.4
Prospective memory result	0.5	0.7	2.3	1.5	1.2	0.7	0.1	0.3	0.3	0.3	1.5	-0.3	0.0
Lung cancer (father)	0.4	0.5	1.2	-0.7	-0.5	0.2	0.3	-0.9	0.5	-0.8	-1.1	-1.0	0.5
Illnesses of mother	1.2	1.5	4.2	-1.5	-1.3	-0.5	1.0	1.8	2.0	-1.1	1.0	0.1	-0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	3.3	-1.6	-1.6	-0.3	-1.3	-0.3	0.4	-1.8	1.0	-1.1	-1.7
Pulse wave Arterial Stiffness index	0.8	1.0	4.7	0.4	0.2	-0.5	-1.2	-1.3	-1.1	0.1	2.2	0.1	-0.4
Impedance of arm (left)	1.5	6.8	14.0	-3.4	-3.4	0.4	0.2	3.7	2.5	-3.1	-3.7	-1.2	-0.1
Arm fat mass (right)	3.4	14.0	31.7	4.6	4.7	0.0	-1.8	-4.9	-5.6	4.5	2.1	-3.3	-1.2
Trunk predicted mass	0.9	5.1	11.8	2.5	2.6	0.2	-1.0	-3.1	-3.0	2.4	3.4	-0.8	-1.1
Standing height	0.1	1.1	2.8	-1.0	-1.3	0.8	-1.7	0.7	-0.2	-1.2	0.6	-1.4	-0.8
Length of working week for main job	0.9	0.9	5.1	-0.4	-0.7	0.5	-2.2	-1.1	0.1	-1.0	0.6	-0.8	-0.6
Exposure to tobacco smoke at home	0.7	0.8	2.4	-1.1	-1.1	0.0	0.6	-0.6	0.1	-1.1	-1.6	1.0	0.4
Breastfed as a baby	1.7	2.2	8.9	-0.3	-0.2	2.3	-1.7	1.3	0.1	-0.2	-1.7	-3.0	0.5
Tense / ‘highly strung’	0.3	0.5	2.9	0.5	0.3	-0.7	-1.7	0.5	0.0	0.0	0.6	-0.7	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.3	5.7	0.6	0.7	-0.9	-2.4	-0.8	-0.6	0.7	-0.5	-1.8	-0.6
Hair/balding pattern: Pattern 4	1.3	3.2	23.7	0.4	0.3	0.9	1.1	-1.2	-0.2	0.0	4.9	1.9	0.2
Birth weight of first child	1.0	1.8	5.0	-0.9	-1.0	-0.9	-1.6	-0.7	0.9	-1.2	-0.3	-2.2	-2.2
Peak expiratory flow (PEF)	0.3	0.7	1.7	-0.9	-0.8	0.2	-0.2	-1.0	0.2	-0.8	1.2	-0.7	-1.3
Pulse wave reflection index	0.7	0.9	2.4	1.0	1.1	1.6	-0.7	0.2	-0.5	1.2	1.1	-0.9	-0.0
Ever highly irritable/argumentative for 2 days	1.6	1.9	8.6	1.9	1.7	-0.7	-0.6	0.3	-1.3	2.9	0.4	0.5	0.9
Loud music exposure frequency	2.0	2.2	5.8	-1.9	-1.9	-2.4	-0.0	-1.4	-0.6	-1.1	0.5	-0.0	-2.2
Qualifications: O levels/GCSEs or equivalent	2.8	4.5	24.7	-0.3	-0.3	0.7	-1.5	5.0	1.5	0.0	-2.3	-2.8	1.2
Mouth/teeth dental problems: Bleeding gums	3.3	4.2	9.5	3.1	2.9	1.6	-2.4	-0.5	-1.6	2.7	-0.7	-1.1	2.1
Blood clot in the leg (DVT)	0.4	0.5	2.2	0.3	0.1	1.2	-1.0	0.2	-0.4	-0.2	-0.1	-0.6	1.5
Medication: Paracetamol	0.8	1.3	2.7	1.6	1.3	0.4	-0.9	-1.5	-0.7	1.2	1.5	0.2	1.2
Headache pain in last month	1.9	3.2	8.6	2.9	2.9	1.4	0.4	-1.2	-1.0	2.7	1.6	1.0	0.6
Medication for cholesterol, blood pressure or diabetes	0.6	1.1	2.5	-1.6	-1.5	-0.0	1.0	0.7	0.6	-1.6	-1.0	0.1	-0.8
Glaucoma (self-reported)	0.7	0.8	4.0	-0.3	-0.2	-2.0	0.1	-0.9	-1.0	-0.2	0.2	0.7	-1.2
Gout (self-reported)	2.1	2.9	8.2	2.9	2.9	1.2	-0.3	-0.5	-1.5	2.5	0.5	-0.5	1.6
Hypothyroidism/myxoedema (self-reported)	1.7	3.3	9.8	1.5	1.2	0.6	0.6	-0.9	0.4	1.4	3.1	3.0	2.6
Medication: Amlodipine	0.2	0.3	1.8	0.5	0.6	0.1	-0.1	-1.3	0.1	-0.2	0.5	-0.6	-0.1
Medication: Ventolin 100micrograms inhaler	0.4	0.6	1.6	-0.5	-0.8	-1.1	-0.5	-1.3	-0.6	-0.5	-0.6	-0.2	-0.9
Birth weight	0.7	1.6	9.2	0.4	0.2	0.6	-0.5	-1.0	1.0	-0.3	3.0	1.7	-1.0
Chronic bronchitis/emphysema (mother)	1.0	1.2	3.7	1.3	1.2	0.5	0.3	-1.9	-1.4	1.2	0.9	0.6	0.4
High blood pressure (siblings)	2.6	3.7	8.4	2.7	2.6	1.5	-0.6	0.5	-1.1	2.9	-2.2	-1.5	1.7
Forced vital capacity (FVC), Best measure	0.6	2.2	6.0	-1.9	-1.8	-0.4	-1.2	0.5	1.3	-2.4	1.2	-1.2	-1.8
Body fat percentage	2.4	9.4	19.8	3.7	3.7	0.1	-1.9	-3.7	-4.5	3.4	0.8	-3.9	-1.2
Leg fat percentage (right)	2.1	7.8	18.2	3.6	3.6	-0.0	-0.5	-4.3	-3.9	3.4	1.6	-1.9	-1.1
Arm fat-free mass (right)	1.2	6.3	13.2	2.9	2.8	-0.4	-1.4	-3.5	-3.2	2.6	3.6	-0.9	-1.0
Exposure to tobacco smoke outside home	0.9	1.2	3.1	1.6	1.3	-0.9	-1.5	0.4	0.3	1.8	0.5	-0.3	1.2
Comparative body size at age 10	0.6	1.5	6.5	-0.3	-0.1	-0.9	1.0	-2.0	-2.5	1.0	1.1	0.8	-0.2
Number of full brothers	0.2	0.3	0.7	0.3	0.1	0.8	-0.2	-0.1	0.7	0.2	-0.9	0.6	0.8
Worry too long after embarrassment	0.7	1.2	3.2	-1.4	-1.4	-1.0	-0.9	1.2	-0.1	-0.8	-1.8	-0.1	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.8	0.4	0.5	-0.9	-0.2	-0.8	-1.4	0.7	-0.2	0.5	0.7
Wheeze or whistling in the chest in last year	1.5	2.7	15.2	0.1	-0.2	-0.9	-1.1	-3.9	-1.7	-0.4	2.0	1.2	-1.1
Number of children fathered	1.4	1.5	3.3	1.6	1.2	0.7	-1.8	-0.4	-1.8	1.8	0.1	0.1	0.9
Reason for reducing amount of alcohol drunk: Health precaution	1.8	2.1	5.1	-1.2	-1.1	-0.9	-0.4	2.0	2.3	-1.5	-1.1	-2.1	0.1
Age at first live birth	1.3	2.3	10.1	-1.0	-0.9	0.7	-1.8	3.2	0.3	-1.2	-1.5	-1.9	0.0
Pulse wave peak to peak time	0.9	1.0	4.4	-0.7	-0.5	0.5	1.3	1.4	1.0	-0.4	-2.1	-0.1	0.1
Health satisfaction	0.7	0.9	2.7	-0.5	-0.3	-0.9	1.2	-1.7	-0.3	-0.5	0.6	0.8	-1.4
Shortness of breath walking on level ground	0.7	0.9	2.3	-0.2	-0.3	-1.5	-0.1	-1.4	-1.5	0.1	1.4	0.2	-0.4
Qualifications: College or University degree	2.2	6.9	34.1	-2.1	-2.2	1.1	-1.3	5.8	2.1	-1.7	-3.1	-1.7	1.6
Eye problems/disorders: None of the above	0.5	0.5	0.9	0.7	0.9	0.3	-0.6	-0.7	-0.9	0.7	0.9	-1.0	-0.1
Mouth/teeth dental problems: Loose teeth	0.7	0.9	2.5	0.8	1.0	-0.4	-0.6	-0.6	-1.1	0.4	-1.5	-1.6	-0.3
Emphysema/chronic bronchitis	0.9	1.1	3.9	0.9	0.4	0.4	-0.7	-2.0	-1.3	0.9	1.0	1.2	0.5
Medication for pain relief, constipation, heartburn	0.9	1.6	7.8	-1.2	-0.9	-0.0	0.3	2.8	1.6	-0.8	-1.2	-0.6	-1.0
Neck or shoulder pain in last month	1.5	2.2	5.7	1.7	1.4	1.1	-0.0	-0.0	0.2	2.0	2.4	1.2	2.1
Medication: Blood pressure	0.5	0.9	1.6	1.3	1.1	-0.1	-1.1	-1.2	-0.4	1.0	1.3	0.2	0.6
Angina (self-reported)	1.2	1.6	5.7	1.7	1.5	0.5	-0.4	-2.4	-1.1	0.8	1.4	0.5	-0.8
Migraine (self-reported)	0.4	0.5	1.9	0.2	0.2	-1.4	-0.6	-0.0	-0.8	1.1	-0.4	-0.5	-0.0
Medication: Ibuprofen	0.4	0.5	1.6	0.6	0.6	0.3	1.1	0.2	-0.5	0.9	0.7	0.1	1.3
Medication: Allopurinol	0.8	1.0	2.7	1.2	1.3	0.2	-0.6	-1.3	-1.6	0.9	-0.2	-1.0	0.2
Medication: Omeprazole	1.6	1.9	3.9	1.8	1.9	0.9	0.4	-1.0	-1.6	1.9	2.0	0.3	0.2
Medication: Seretide 50 evohaler	0.8	0.9	2.9	-0.2	-0.4	-0.5	-0.7	-1.7	-0.4	-0.8	1.3	-0.2	-1.7
Mean time to correctly identify matches	2.7	5.1	20.4	0.3	0.4	1.2	-0.3	4.2	2.2	0.1	-2.3	-4.5	0.8
Heart disease (mother)	0.9	1.1	5.1	-0.1	-0.4	-0.6	-0.8	-2.2	-0.0	-0.6	1.5	1.2	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	2.0	-0.3	-0.4	-0.1	-1.4	0.2	1.3	-0.9	-0.3	-0.8	-0.5
Whole body fat mass	2.8	11.7	25.4	4.2	4.1	-0.0	-2.4	-4.3	-5.0	3.9	1.6	-3.8	-1.2
Leg fat mass (right)	3.1	12.0	25.4	4.3	4.3	-0.1	-1.8	-5.0	-4.9	4.1	2.1	-2.8	-1.0
Arm predicted mass (right)	1.3	6.6	13.6	2.9	2.8	-0.1	-1.4	-3.7	-3.4	2.5	3.6	-1.3	-1.0
Pulse rate, automated reading	0.3	1.1	4.5	1.0	0.7	-0.6	-0.4	2.1	0.2	1.1	-0.3	-0.8	1.5
Alcohol intake frequency.	0.3	0.8	2.9	0.2	-0.2	-1.4	0.4	-0.9	0.6	-0.5	1.0	1.7	-0.4
Comparative height size at age 10	0.4	2.1	7.4	-1.0	-1.2	-0.7	-1.6	-0.6	-1.7	-1.1	-1.1	-2.7	-1.2
Number of full sisters	2.0	2.4	11.2	-1.0	-1.3	-0.4	-1.4	0.7	1.5	-1.2	-3.4	-1.0	-1.7
Suffer from ‘nerves’	0.3	0.5	1.9	0.2	0.2	-1.4	0.4	0.4	-0.7	0.7	0.2	0.5	1.0
Overall health rating	1.1	2.4	12.9	0.8	0.7	-0.7	0.8	-3.6	-1.1	0.9	2.1	1.5	-0.9
Chest pain or discomfort	0.4	0.6	2.7	0.2	-0.2	-0.8	-1.1	-1.6	-1.1	0.3	0.3	0.3	0.5
Had major operations	0.6	0.7	2.2	0.5	0.4	0.6	-0.4	-1.3	-1.1	0.9	-0.4	-1.5	-0.2
Age at last live birth	0.5	0.7	3.0	-0.3	-0.2	0.2	-0.6	1.4	-0.6	-0.5	-0.5	-1.7	-0.5
Family relationship satisfaction	1.0	1.3	3.4	-1.1	-0.6	-0.8	1.7	0.8	1.2	-1.3	0.7	-0.0	-1.8
Leg pain on walking	0.4	0.5	2.2	0.6	0.6	-0.6	0.3	-0.3	0.9	-0.0	0.9	0.3	-1.5
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	2.3	0.5	0.5	-0.5	0.7	-0.1	-1.5	0.7	-0.1	-1.1	-0.0
Commuting to job workplace: Car/motor vehicle	1.7	1.9	5.1	1.8	1.3	0.9	-1.4	-1.2	-1.2	2.3	1.5	-0.1	1.3
Illness, injury, bereavement, stress in last 2 years	1.5	1.8	5.3	-1.8	-1.6	-0.1	-0.3	2.3	1.3	-1.8	-0.8	-0.7	-0.9
Medication: Aspirin	0.9	1.2	5.0	-1.0	-1.2	-0.5	0.3	-2.2	0.1	-1.8	0.0	-0.4	-1.0
Supplements: Vitamin C	1.0	1.2	4.4	-0.4	-0.3	-0.3	1.1	-1.2	0.3	-0.6	0.1	2.1	-2.1
Knee pain experienced in last month	1.9	2.9	6.7	2.2	1.8	-0.2	-1.3	-1.5	-1.1	2.6	2.0	1.5	1.8
Hypertension (Self-reported)	0.6	1.6	4.0	2.0	2.0	-0.1	-0.4	0.4	-0.5	1.5	1.1	-0.3	2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	1.2	0.1	-0.2	-0.1	-0.9	-1.1	-0.1	-0.3	0.9	0.1	-0.0
Illnesses of father: Heart disease	1.5	2.1	4.7	2.1	1.8	1.3	-1.5	-0.2	-1.3	2.2	0.2	-1.0	1.3
Illnesses of siblings: Diabetes	0.5	0.6	1.9	0.6	0.6	-0.6	0.1	-1.2	0.3	1.0	-1.4	-0.1	0.2
Smoking status: Previous	0.9	1.4	4.6	-0.1	-0.1	-0.5	-0.3	-2.2	-1.6	0.2	1.5	-0.7	-1.9
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	1.1	-0.2	-0.4	-0.0	-1.0	-0.5	-0.4	-0.4	-0.3	0.3	0.2
Whole body fat-free mass	1.3	7.2	13.5	3.1	3.1	-0.1	-1.5	-3.6	-3.7	3.1	3.4	-1.5	-1.1
Leg fat-free mass (right)	1.7	9.3	20.5	3.5	3.5	-0.7	-2.2	-4.0	-4.5	3.5	2.9	-2.2	-1.2
Arm fat percentage (left)	2.9	11.4	24.9	4.2	4.3	-0.2	-1.7	-4.1	-5.0	4.1	1.3	-3.7	-1.3
Average weekly red wine intake	1.2	1.8	9.4	-0.9	-0.6	0.2	-1.6	1.4	0.6	-0.5	-1.5	-3.1	-0.2
Handedness (chirality/laterality): Left-handed	0.7	0.9	2.3	1.2	1.3	1.5	-0.2	-0.2	-1.0	1.0	0.4	0.5	1.1
Mood swings	0.7	1.3	3.3	1.1	1.0	-1.1	-1.8	-0.4	-1.2	1.7	0.9	-0.2	-0.1
Loneliness, isolation	0.9	1.2	3.9	1.0	0.9	-0.9	-0.9	-0.4	-1.6	2.0	0.1	0.6	1.4
Long-standing illness, disability or infirmity	0.4	0.6	1.8	0.9	0.7	-0.9	-0.8	-0.8	-1.3	1.0	-0.1	-0.4	0.2
Ever had bowel cancer screening	0.6	0.7	2.5	0.4	0.1	0.7	-1.4	0.7	0.8	0.6	-0.6	-0.8	1.6
Diabetes diagnosed by doctor	1.1	1.8	4.0	0.6	0.6	-1.4	-1.5	-2.0	-2.0	0.2	1.2	-1.5	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.6	3.5	1.3	1.3	1.9	0.6	-1.8	-1.3	1.6	0.3	0.9	-0.1
Friendships satisfaction	1.2	1.5	3.4	-1.5	-1.1	-1.9	1.2	1.2	1.1	-1.1	-1.2	0.3	-1.0
Qualifications: nursing, teaching	1.4	2.2	11.8	-1.1	-1.1	-0.0	-0.4	3.4	1.6	-1.0	-0.9	-1.8	0.1
Commuting to job workplace: Walk	1.9	2.1	4.5	-1.8	-1.9	-0.6	0.3	1.5	1.8	-1.4	-2.1	0.6	-0.9
Eye problems/disorders: Cataract	1.3	1.5	7.2	0.0	-0.5	0.8	-1.0	2.1	0.9	0.5	-0.9	0.1	2.7
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	2.5	-0.3	-0.4	-1.6	-0.2	1.4	0.3	0.1	-0.2	-1.3	-0.2
Medication for cholesterol	0.4	0.5	3.6	0.5	0.2	0.7	-1.9	0.2	0.3	0.5	0.7	0.5	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.4	1.6	6.6	0.2	0.3	-1.3	0.9	-2.6	-1.5	0.1	1.8	1.0	-0.5
Back pain experienced in last month	2.2	3.2	10.8	1.7	1.5	-0.9	0.3	-2.3	-0.0	1.7	3.3	2.7	0.5
Mineral and other dietary supplements	0.9	1.2	4.5	-0.0	0.1	0.6	-0.7	1.6	-0.6	0.0	-2.1	-1.3	1.2
Breast cancer (self-reported)	0.7	0.8	3.9	-0.1	0.3	0.9	2.0	0.3	1.3	-0.3	1.1	-0.4	-0.6
Asthma (self-reported)	0.5	1.0	3.6	-0.4	-0.7	-1.1	-1.2	-1.9	-0.6	-0.5	-1.0	-0.2	-1.0
Osteoporosis (self-reported)	0.2	0.3	1.1	0.2	0.5	0.3	1.0	-0.6	-0.7	0.3	-0.5	0.2	0.0
Osteoarthritis (self-reported)	0.9	1.2	2.0	1.4	1.2	-1.4	-0.9	-1.1	-0.9	1.3	1.4	0.7	0.1
Medication: Aspirin	0.8	1.0	5.2	-0.6	-0.6	0.1	0.1	-2.3	-0.3	-1.3	-0.4	-1.1	-1.1
Medication: Gliclazide	0.5	0.5	1.7	0.8	0.8	-0.7	-0.9	-0.3	-1.3	1.0	0.1	0.3	0.1
Illnesses of father: None of the above (group 1)	1.4	1.7	4.8	-1.5	-1.2	0.3	2.2	2.1	0.8	-1.7	-0.1	0.5	-0.9
Smoking status: Current	1.9	3.1	8.7	-1.5	-1.1	-1.5	1.2	-2.5	0.8	-2.7	0.4	1.0	-3.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	2.0	-0.5	-0.5	0.3	-0.2	-0.7	0.3	-0.7	1.4	-0.6	-0.1
Whole body water mass	1.3	7.3	14.3	3.1	3.1	-0.1	-1.5	-3.5	-3.8	3.1	3.4	-1.6	-1.0
Leg predicted mass (right)	1.7	8.9	20.3	3.4	3.4	-0.7	-2.1	-3.9	-4.5	3.5	2.8	-2.2	-1.2
Arm fat mass (left)	3.2	13.1	27.7	4.6	4.7	0.0	-1.8	-4.5	-5.3	4.5	1.9	-3.4	-1.2
Number of self-reported non-cancer illnesses	1.3	2.2	5.0	2.2	2.2	0.6	0.1	-1.3	-1.2	2.2	0.9	0.8	1.6
Average weekly champagne plus white wine intake	1.1	1.6	4.3	-2.0	-2.1	-0.6	-0.4	0.6	1.3	-1.6	0.4	0.9	-1.1
Miserableness	1.4	2.5	8.1	1.7	1.5	-0.0	-2.8	-0.9	-1.5	2.4	1.3	-0.3	1.2
Guilty feelings	0.5	0.8	2.3	0.9	1.0	-0.5	0.6	-1.0	-1.2	1.5	0.5	0.6	0.1
Wears glasses or contact lenses	1.1	1.2	4.2	1.3	1.1	0.3	-0.2	2.0	0.6	1.4	-0.3	0.3	1.7
Ever taken oral contraceptive pill	1.8	2.1	6.8	0.4	0.2	1.5	0.6	0.9	2.4	0.4	1.1	2.6	1.7
Hearing aid user	0.3	0.4	2.0	-0.3	0.0	-1.4	0.1	0.3	0.2	0.4	-0.6	-0.8	0.6
Mother’s age at death	0.7	0.9	3.3	-0.4	-0.5	0.2	-0.5	0.4	-1.8	-0.3	-1.8	-1.1	0.6
Financial situation satisfaction	1.0	1.2	4.3	0.1	0.5	-0.2	2.1	-0.6	0.8	-0.5	1.7	0.4	-1.9
Tinnitus: Yes, now most or all of the time	0.5	0.6	3.2	0.3	0.3	0.7	0.6	-0.7	-0.1	-0.4	1.8	0.9	-0.5
Commuting to job workplace: Public transport	3.6	4.3	9.2	-2.4	-2.3	-1.3	0.1	3.0	2.5	-2.8	-1.8	-1.4	-1.5
Eye problems/disorders: Glaucoma	0.4	0.5	1.4	-0.1	-0.3	-0.9	-0.5	0.4	0.2	-0.5	0.0	1.2	-1.2
Medication: Blood pressure	0.2	0.4	2.9	-0.2	0.0	-0.5	1.7	0.2	-0.9	-0.5	0.2	0.3	0.1
Pain type(s) experienced in last month: Hip pain	1.3	1.6	5.5	1.0	0.8	-0.6	0.3	-0.6	-0.5	1.4	1.1	2.4	2.2
Supplements: Fish oil (including cod liver oil)	0.3	0.4	1.2	0.4	0.2	-0.1	-0.0	-0.6	1.1	0.3	1.1	0.8	0.3
High cholesterol (Self-reported)	0.3	0.4	2.2	0.1	0.3	-1.5	-0.2	-0.9	-0.3	0.3	1.0	-0.1	-0.3
Medication: Bendroflumethiazide	0.2	0.4	1.2	0.4	0.1	-1.1	-0.8	0.2	-0.6	1.1	-0.4	-0.1	-0.1
Medication: Paracetamol	1.8	2.7	7.6	2.4	2.2	1.4	-0.3	-0.6	-0.7	1.9	2.8	-0.0	1.7
Medication: Lisinopril	0.3	0.4	1.1	-1.0	-0.8	-0.7	-0.3	0.5	0.0	-1.1	-0.4	-0.6	-0.2
Medication: Atorvastatin	1.0	1.2	5.2	0.9	0.9	-0.5	-1.2	-0.8	-2.3	1.1	0.7	-0.8	0.4
Illnesses of father: High blood pressure	0.6	0.8	3.2	-0.3	-0.4	-1.1	-1.5	-0.4	0.2	0.2	-1.8	-0.3	0.4
Alcohol drinker status: Never	0.8	1.0	3.8	-0.5	-0.8	-0.7	0.3	0.6	2.0	-0.6	0.1	1.8	0.5
Ever smoked	2.2	3.8	17.7	-2.0	-1.6	-1.3	0.3	-1.3	-0.0	-2.0	0.3	-2.5	-4.2
Basal metabolic rate	1.6	8.8	17.8	3.5	3.5	-0.1	-1.7	-4.0	-4.2	3.4	3.4	-1.8	-1.2
Leg fat percentage (left)	2.5	9.2	20.0	3.9	4.0	-0.0	-0.9	-4.5	-4.2	3.6	1.7	-2.2	-1.1
Arm fat-free mass (left)	1.5	7.8	14.9	3.3	3.3	0.2	-1.3	-3.7	-3.9	3.0	3.7	-1.3	-0.8
Number of operations (self-reported)	1.1	1.6	3.7	1.7	1.7	-0.1	-0.7	-1.4	-1.7	1.9	0.9	-0.1	0.5
Average weekly beer plus cider intake	0.4	0.6	3.7	-0.1	-0.1	-1.9	-0.1	0.3	0.9	0.0	0.8	0.9	0.3
Irritability	2.4	4.1	7.6	2.7	2.7	-0.8	-2.5	0.5	-1.4	2.3	1.4	-2.8	1.6
Risk taking	0.9	1.3	5.0	-0.8	-0.5	-2.2	-0.6	-1.6	-0.8	-1.0	1.4	-0.4	-0.7
Ever had prostate specific antigen (PSA) test	1.1	1.3	3.9	-1.6	-1.4	-0.5	0.4	-0.2	0.4	-1.8	0.4	0.3	-2.0
Fractured/broken bones in last 5 years	1.1	1.4	3.4	-1.0	-1.2	-0.5	-0.2	1.8	0.8	-1.0	-1.8	-1.8	-0.2
Age started oral contraceptive pill	2.5	3.1	16.1	-1.2	-0.7	-0.1	0.9	4.0	1.4	-0.6	-1.4	-2.7	-0.6
Diastolic blood pressure, automated reading	3.1	9.7	26.4	5.1	4.5	3.2	-2.2	0.8	-0.7	4.4	0.4	-0.6	3.9
Ever depressed for a whole week	0.3	0.4	1.0	0.3	0.8	-0.8	-0.0	0.6	0.2	0.9	1.0	-0.3	-0.5
Unable to work because of sickness or disability	0.9	1.2	4.6	-0.9	-1.0	-2.1	-0.4	-2.1	-0.3	-0.5	0.3	0.1	-0.6
Commuting to job workplace: Cycle	1.0	1.2	3.6	-1.6	-1.4	0.0	0.6	-0.8	0.3	-1.9	-0.6	0.4	-1.7
Myopia	1.2	1.8	5.6	0.4	0.5	0.3	-1.5	1.9	1.3	0.7	-1.5	-2.4	1.5
Vascular/heart problems diagnosed by doctor	0.9	2.4	6.7	-2.6	-2.5	-0.6	0.7	0.6	1.1	-1.8	-1.1	0.3	-2.0
Cholesterol lowering medication	1.2	1.7	4.9	0.1	0.5	-0.9	2.0	-2.2	-1.8	0.2	1.2	0.2	-1.5
Medication: Omeprazole (e.g. Zanprol)	2.4	2.9	6.5	2.5	2.5	1.4	-0.3	-1.1	-1.5	2.3	2.1	-0.2	0.9
Pain experienced in last month	2.8	4.7	11.1	-3.2	-3.1	0.4	-0.0	2.3	1.3	-3.3	-2.7	-1.3	-0.8
Supplements: Calcium	0.7	0.8	2.7	-0.5	-1.1	-0.0	-1.6	-0.3	1.2	-1.0	0.0	1.1	0.2
Basal cell carcinoma (self-reported)	0.5	0.6	2.7	-0.2	-0.1	-0.3	0.9	-1.6	-0.8	0.2	-0.7	-0.9	-0.1
Heart attack/myocardial infarction (self-reported)	0.8	1.1	4.6	0.5	0.3	0.8	-1.3	-2.1	-1.5	-0.3	0.3	-0.8	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	2.2	0.3	0.0	1.1	-1.4	0.3	-0.1	-0.3	-0.3	-0.8	1.5
Heart disease (siblings)	0.5	0.6	1.8	0.1	0.1	-0.7	1.3	-1.2	-1.3	0.1	-0.6	-0.6	0.3
Alcohol drinker status: Previous	0.6	0.7	3.4	-0.5	-0.5	-1.9	0.7	-0.3	1.0	-0.6	-0.2	1.0	-0.6
Pack years of smoking	2.3	3.3	13.2	-0.1	-0.3	-0.4	0.7	-3.2	0.7	-0.5	2.7	3.6	-1.1
Impedance of whole body	1.8	9.3	16.7	-4.0	-4.0	0.8	0.9	4.1	3.5	-4.1	-3.7	-0.7	0.1
Leg fat mass (left)	3.3	12.8	25.4	4.5	4.6	-0.0	-2.0	-5.0	-5.0	4.2	2.1	-2.9	-0.9
Arm predicted mass (left)	1.5	7.8	13.6	3.5	3.4	0.2	-1.3	-3.7	-3.6	3.2	3.6	-1.2	-0.7