Best TWAS P=2.85e-11 · Best GWAS P=2.88e-15 conditioned to 0.0355
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Female) | HOTAIRM1 | 0.26 | 0.02 | lasso | 4 | 0.04 | 1.8e-02 | 3.9 | 6.0 | 2.1e-09 | 0.58 | 0.06 | 0.68 | FALSE |
| 2 | GTEx | Lung | HOTAIRM1 | 0.25 | 0.18 | lasso | 7 | 0.14 | 4.3e-11 | 3.9 | 5.2 | 1.7e-07 | 0.42 | 0.99 | 0.01 | FALSE |
| 3 | GTEx | Stomach | HOTAIRM1 | 0.14 | 0.12 | lasso | 5 | 0.15 | 8.8e-08 | 6.0 | 6.6 | 3.7e-11 | 0.43 | 0.12 | 0.81 | FALSE |
| 4 | YFS | Blood | HOXA9 | 0.06 | 0.05 | lasso | 6 | 0.06 | 2.0e-19 | 7.8 | -6.5 | 7.0e-11 | -0.47 | 0.01 | 0.99 | FALSE |
| 5 | The Cancer Genome Atlas | Breast Invasive Carcinoma | HOXA10 | 0.02 | 0.01 | blup | 53 | 0.01 | 9.0e-03 | 6.7 | -5.6 | 2.6e-08 | -0.68 | 0.03 | 0.26 | TRUE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | HOXA9 | 0.04 | 0.04 | lasso | 2 | 0.04 | 1.4e-04 | 6.4 | -6.7 | 2.8e-11 | -0.43 | 0.02 | 0.95 | TRUE |