Best TWAS P=8.33e-10 · Best GWAS P=3.92e-11 conditioned to 0.00623
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | ZMIZ2 | 0.12 | 0.09 | lasso | 4 | 0.06 | 2.3e-05 | -5.4 | -5.8 | 6.1e-09 | 0.68 | 0.03 | 0.96 | FALSE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | PPIA | 0.05 | 0.02 | enet | 5 | 0.03 | 7.7e-05 | -6.6 | -6.1 | 8.3e-10 | 0.82 | 0.00 | 0.95 | TRUE |