TWAS hub - ZMIZ2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cortex	0.4860	0.1280	1.4e-03	0.074	NA	0.024	NA	0.006	4.3e-03	NA	7.1e-02	NA	2.1e-01
2	GTEx	Cells Transformed fibroblasts	0.1230	0.0440	8.4e-04	0.086	NA	0.057	NA	0.061	5.7e-07	NA	4.1e-05	NA	2.3e-05
3	GTEx	Nerve Tibial	0.1225	0.0531	5.2e-03	0.065	NA	0.043	NA	0.059	2.3e-05	NA	5.2e-04	NA	5.1e-05
4	GTEx	Thyroid	0.1120	0.0500	6.2e-03	0.073	NA	0.052	NA	0.049	2.9e-06	NA	7.2e-05	NA	1.2e-04
5	NTR	Blood	0.0849	0.0197	4.8e-14	0.058	0.055	0.060	0.058	0.056	4.6e-18	2.5e-17	1.5e-18	5.0e-18	2.0e-17
6	ROSMAP	Brain Pre-frontal Cortex	0.1026	0.0310	7.8e-06	0.061	0.032	0.072	0.040	0.064	2.3e-08	4.7e-05	1.3e-09	6.1e-06	1.2e-08
7	TCGA	Soft Tissue Sarcoma	0.0520	0.0310	7.2e-03	0.018	0.022	0.001	NA	0.009	2.7e-02	1.7e-02	2.6e-01	NA	8.6e-02
8	TCGA	Thyroid Carcinoma	0.0650	0.0340	7.9e-05	0.027	0.032	0.026	NA	0.026	1.0e-03	3.8e-04	1.4e-03	NA	1.4e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Blood Red Count	9.1	88.2	216.1	7.6	-7.6	9.0	-0.6	-14.7	8.7	4.0	14.2
Noisy workplace	8.6	10.6	17.2	2.0	-3.7	3.2	0.6	-4.1	4.0	3.1	3.6
Blood Platelet Count	8.3	96.0	252.8	5.1	-9.0	9.0	-1.5	-14.4	9.9	4.5	15.9
Intelligence (Savage-Jansen 2018)	6.9	21.1	36.0	-1.4	5.2	-6.0	-2.5	5.5	-5.1	-5.0	-4.0
Qualifications: NVQ or HND or HNC or equivalent	6.6	8.0	17.1	2.4	-3.3	2.1	0.4	-4.1	2.9	1.8	3.8
Fluid intelligence score	5.3	11.0	18.4	-1.9	4.3	-4.3	-1.1	3.8	-3.9	-2.9	-2.9
Mouth/teeth dental problems	5.1	7.9	16.0	-2.4	1.0	-1.9	-2.7	3.1	-4.0	-3.7	-2.5
Verbal and Numeric Reasoning (VNR)	4.9	11.8	20.7	-1.4	4.6	-4.1	-1.6	4.0	-4.1	-3.6	-2.6
Medication for pain relief, constipation, heartburn	4.6	7.8	17.1	-2.1	1.5	-3.7	-1.5	3.2	-4.1	-2.7	-2.3
Mean time to correctly identify matches	4.5	8.5	28.2	0.7	1.1	2.7	5.3	-2.3	3.9	3.2	0.7
Diabetes diagnosed by doctor	4.5	7.4	12.1	2.8	-3.3	3.5	0.0	-2.7	3.2	1.5	2.9
Diabetes (self-reported)	4.4	6.7	12.9	1.9	-3.0	3.5	0.8	-2.2	3.6	2.2	2.4
Alcohol intake frequency.	4.2	9.7	25.4	3.0	-3.2	3.2	-2.5	-3.6	1.7	-0.6	5.0
Body mass index (BMI)	3.9	16.8	45.3	2.1	-6.7	4.1	-2.9	-4.2	3.2	0.4	5.6
Reaction Time	3.8	7.2	25.8	1.2	2.4	1.3	5.1	-1.9	3.5	2.6	0.5
Leg fat percentage (right)	3.7	13.4	41.9	1.9	-6.5	2.9	-2.3	-4.0	2.8	0.4	4.8
Leg fat percentage (left)	3.7	13.3	42.6	1.6	-6.5	3.1	-2.2	-3.9	2.8	0.7	4.8
Medication: Ibuprofen (e.g. Nurofen)	3.6	4.5	7.4	2.5	-0.1	2.1	2.4	-2.7	2.7	1.9	1.3
Exposure to tobacco smoke outside home	3.6	4.8	13.0	1.9	-1.5	2.0	0.3	-3.6	2.2	0.9	3.1
Medication: Metformin	3.4	4.8	10.6	3.3	-2.7	1.5	0.5	-2.6	2.5	1.7	1.5
Age at First Birth	3.3	4.8	11.9	-2.6	1.9	-1.9	1.1	3.1	-1.1	0.2	-3.5
Type 2 Diabetes (T2D) (2018)	3.3	6.2	11.8	2.4	-3.4	2.6	0.8	-2.5	3.1	2.3	2.0
Qualifications: College or University degree	3.3	10.4	21.9	-3.5	3.6	-3.0	0.0	4.7	-3.2	-1.5	-3.7
Illness, injury, bereavement, stress in last 2 years	3.3	4.0	9.4	-1.0	2.0	-1.9	-0.4	2.2	-3.1	-2.1	-2.2
Leg fat mass (left)	3.3	12.7	38.8	1.6	-6.2	2.9	-3.3	-3.4	2.2	-0.3	5.0
Blood White Count	3.2	23.7	54.6	4.5	-5.7	3.6	-1.6	-7.3	3.5	0.9	7.4
Tinnitus: Yes, but not now, but have in the past	3.2	3.5	7.5	1.8	-2.5	2.7	-1.5	-1.3	1.0	-0.3	2.4
Leg fat mass (right)	3.2	12.5	37.6	1.6	-6.1	2.8	-3.3	-3.5	2.2	-0.4	4.9
Type 2 Diabetes (T2D) (2012)	3.1	3.6	9.2	2.0	-1.6	2.4	0.6	-3.0	1.6	0.9	1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	3.1	4.2	9.4	0.9	-2.3	3.1	-0.2	-2.4	2.5	1.2	2.1
Medication: Aspirin	3.1	4.1	8.4	1.1	-2.9	2.5	0.1	-1.5	2.9	1.9	1.8
Ever taken oral contraceptive pill	3.1	3.5	7.9	-1.5	2.2	-2.1	1.5	2.1	-1.3	0.2	-2.8
Risk taking	3.1	4.5	10.5	1.5	-0.7	1.4	2.6	-2.1	3.0	3.2	0.6
Friendships satisfaction	3.0	3.8	13.8	1.0	3.7	-2.1	1.0	1.6	-1.4	-0.6	-2.2
Qualifications: None of the above	2.9	6.2	14.8	2.2	-3.4	3.9	-1.4	-2.2	2.2	-0.1	2.5
Hypothyroidism (self reported)	2.8	6.5	14.2	-3.8	1.0	-3.1	-2.5	3.0	-2.3	-2.4	-0.8
Mouth/teeth dental problems: Mouth ulcers	2.8	4.5	7.7	0.5	-1.4	2.6	1.4	-2.3	2.5	2.8	2.3
Breast Cancer	2.7	6.4	13.8	1.9	-0.1	2.9	2.9	-2.9	3.7	2.8	0.8
Coronary Artery Disease (CAD)	2.7	3.2	5.9	-1.1	1.1	-1.8	-1.3	2.4	-2.1	-1.9	-2.1
Eye problems/disorders: Diabetes related eye disease	2.7	3.0	8.8	-0.3	0.5	0.7	3.0	-0.3	2.8	2.4	-0.8
Medication: Ibuprofen	2.7	3.2	7.3	2.1	0.4	1.3	1.8	-2.7	2.2	1.4	1.5
Medication: Aspirin	2.7	3.6	8.0	0.5	-2.8	2.7	-0.2	-1.1	2.6	1.6	1.7
Medication: Gliclazide	2.7	3.1	8.1	2.8	-1.7	1.2	-2.4	-0.8	0.4	-1.4	1.9
Average weekly fortified wine intake	2.6	3.1	6.0	-1.8	1.4	-1.4	-2.0	1.5	-2.3	-2.5	0.0
Relative age voice broke	2.6	4.0	6.2	-1.1	0.4	-2.3	-2.4	2.2	-2.5	-2.5	-1.5
Qualifications: A levels/AS levels or equivalent	2.6	5.7	11.0	-2.9	3.0	-2.5	0.7	3.3	-1.2	-0.5	-3.0
Arm fat mass (right)	2.6	10.5	33.6	1.4	-5.8	2.2	-4.0	-2.4	1.3	-1.1	4.4
Wheeze or whistling in the chest in last year	2.6	4.7	9.3	2.0	-2.0	2.1	0.7	-3.1	2.6	1.5	2.5
Age at first live birth	2.6	4.7	8.5	-2.9	2.8	-2.2	-1.5	1.9	-2.0	-1.9	-1.6
Nervous feelings	2.5	4.7	10.6	-1.6	2.0	-2.4	-1.6	3.2	-2.0	-1.5	-2.5
Medication: Paracetamol	2.5	4.1	11.5	0.6	0.8	3.4	1.0	-2.3	2.5	2.0	1.9
Age at last live birth	2.5	3.6	7.0	-2.0	2.0	-1.8	-2.4	1.3	-1.7	-2.6	-0.4
Arm fat mass (left)	2.5	10.2	31.8	1.4	-5.6	2.3	-3.8	-2.5	1.3	-1.0	4.4
Arm fat percentage (right)	2.4	9.5	33.9	1.5	-5.8	2.2	-2.9	-2.7	2.0	-0.4	4.0
Medication: Paracetamol	2.4	3.7	10.0	0.3	0.2	3.2	0.4	-2.4	2.2	1.8	2.2
Medication for hormone replacement therapy	2.3	2.6	8.9	0.0	1.0	0.4	3.0	-1.2	2.3	2.0	-0.3
Worry too long after embarrassment	2.3	3.8	7.8	1.8	-0.5	2.3	1.5	-2.1	2.8	2.5	1.3
Arm fat percentage (left)	2.3	9.3	32.9	1.2	-5.7	2.1	-3.1	-2.6	1.6	-0.7	4.0
BMI	2.2	13.0	28.2	1.9	-5.3	3.5	-2.5	-3.8	3.2	0.5	5.3
Body fat percentage	2.2	8.8	32.6	1.4	-5.7	1.9	-2.6	-2.8	1.7	-0.3	3.8
Whole body fat mass	2.2	9.3	29.5	1.0	-5.4	1.8	-3.8	-2.4	1.1	-1.3	4.2
Medication: Co-codamol	2.1	2.4	4.8	0.8	-0.7	1.6	0.6	-2.2	2.2	1.4	1.9
Long-standing illness, disability or infirmity	2.1	3.2	9.6	-0.1	-2.1	3.1	-0.6	-1.7	1.4	-0.4	2.5
Chronic bronchitis/emphysema (father)	2.0	2.4	6.0	1.2	-2.4	0.7	-1.6	-2.0	-0.5	-0.4	2.0
Trunk fat mass	2.0	8.4	26.1	0.9	-5.1	1.5	-3.8	-2.1	0.8	-1.5	4.0
Heel bone mineral density (BMD) T-score, automated (right)	2.0	4.6	9.9	1.6	0.6	0.0	3.1	-3.1	2.3	2.6	1.1
Falls in the last year	2.0	2.7	6.4	2.2	-2.5	2.3	0.2	-1.9	0.4	0.4	0.9
Impedance of arm (left)	2.0	9.2	19.5	-1.9	3.4	-4.4	1.1	3.4	-3.2	-1.1	-3.8
Mouth/teeth dental problems: Bleeding gums	2.0	2.6	5.5	1.4	0.2	1.0	2.3	-1.5	1.9	2.3	0.5
Hypothyroidism/myxoedema (self-reported)	2.0	3.9	8.4	-2.9	0.7	-2.0	-2.5	2.6	-1.4	-2.0	-0.1
Pulse wave peak to peak time	2.0	2.4	5.8	1.3	-2.0	2.4	-0.8	-1.4	0.4	0.3	2.2
Schizophrenia (2014)	1.9	4.1	12.2	1.8	-0.6	1.3	2.8	-1.9	1.9	3.5	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	1.9	4.2	12.7	1.0	-0.3	0.7	2.4	-3.6	2.4	2.2	1.9
Serious illness, injury or assault to yourself	1.9	2.3	7.1	-0.6	-1.9	1.4	1.5	-0.1	1.9	2.7	0.2
Financial difficulties in last 2 years	1.9	2.5	6.3	0.3	-0.1	1.4	2.5	-1.3	2.2	2.3	-0.1
Weight	1.9	9.5	24.6	0.7	-5.0	2.2	-4.4	-1.9	0.8	-1.5	4.5
Pulse wave Arterial Stiffness index	1.9	2.3	6.0	-1.2	1.9	-2.4	0.6	1.5	-0.5	-0.3	-2.1
Suffer from ‘nerves’	1.9	3.0	6.7	-2.4	1.4	-1.8	0.7	2.2	-1.0	0.0	-2.6
Hearing aid user	1.9	2.2	8.1	1.3	-0.8	1.0	-0.9	-1.7	1.4	-0.1	2.9
Alzheimer’s Disease (in father)	1.8	2.0	6.1	0.2	1.6	0.5	2.5	-0.7	1.5	1.9	-0.7
Medication: Simvastatin	1.8	2.7	8.7	1.5	-2.1	2.9	-1.0	-0.6	0.9	-1.0	1.6
Length of working week for main job	1.8	2.0	4.3	0.8	-2.1	1.6	-1.7	-1.6	0.3	-0.9	1.5
Qualifications: O levels/GCSEs or equivalent	1.8	2.8	6.6	-1.9	1.5	-2.6	0.5	1.7	-2.1	-0.5	-1.6
Pain type(s) experienced in last month: Hip pain	1.8	2.3	4.4	0.5	-1.3	2.1	1.5	-1.5	1.7	2.0	0.9
Pack years of smoking	1.8	2.7	9.8	1.8	-3.1	1.9	-1.5	-1.2	0.5	0.2	1.1
Major Depression (MDD)	1.7	2.0	6.9	0.2	2.6	-1.6	0.1	1.9	-0.7	-0.1	-1.6
Trunk fat percentage	1.7	6.9	26.4	1.0	-5.1	1.2	-2.9	-2.1	1.0	-0.9	3.4
Number of incorrect matches in round	1.7	2.8	8.5	-0.1	1.1	0.5	2.9	1.1	1.2	2.3	-2.2
Impedance of arm (right)	1.7	8.0	18.7	-1.9	3.1	-4.3	1.5	3.0	-2.6	-0.5	-3.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.7	3.5	6.6	0.8	-0.1	1.4	1.8	-2.5	2.6	1.8	2.5
Average weekly champagne plus white wine intake	1.7	2.4	6.0	-1.6	1.4	0.1	2.5	1.3	0.7	1.6	-1.9
Irritable Bowel Disease (IBD)	1.6	3.9	11.1	1.0	3.3	-2.3	1.4	1.6	-1.3	-0.5	-2.7
Body Mass Index (BMI) (2010)	1.6	2.2	6.7	-0.5	-2.2	0.8	-2.6	-0.2	-1.2	-1.8	0.4
Pack years adult smoking proportion	1.6	2.5	9.4	1.4	-3.1	1.7	-1.8	-1.0	0.1	-0.0	1.1
Qualifications: CSEs or equivalent	1.6	2.1	7.4	1.2	-2.7	0.6	-0.2	-1.9	1.0	1.1	1.3
Illnesses of siblings	1.6	2.2	4.9	-1.7	2.2	-1.8	0.6	1.1	-0.8	0.5	-2.1
Ever highly irritable/argumentative for 2 days	1.6	2.0	5.9	0.9	-1.7	1.4	-1.9	-0.3	0.6	-0.4	2.4
Comparative height size at age 10	1.6	8.6	14.4	-2.4	1.4	-3.6	-2.8	3.4	-3.8	-3.7	-1.2
Impedance of whole body	1.6	8.3	18.8	-1.7	3.3	-4.3	2.1	2.6	-2.7	-0.2	-3.9
Schizophrenia (2018)	1.5	3.2	7.7	2.3	-1.1	1.1	2.4	-1.7	1.1	2.8	-0.5
Ulcerative Colitis (UC)	1.5	2.8	5.9	1.1	2.3	-2.4	0.1	1.6	-1.7	-1.1	-2.0
Ovarian Cancer	1.5	2.0	4.6	0.3	-0.8	1.5	2.0	-0.8	2.0	2.1	-0.1
Relative age of first facial hair	1.5	3.0	6.8	-1.1	0.5	-1.1	-1.6	2.2	-2.6	-2.2	-1.6
Leg fat-free mass (left)	1.5	7.9	25.3	0.7	-3.2	1.9	-5.0	-1.0	0.1	-2.3	4.1
Townsend deprivation index at recruitment	1.5	2.1	5.0	1.9	-0.7	1.1	0.9	-2.2	1.5	1.5	1.0
Leg predicted mass (left)	1.5	8.0	25.8	0.6	-3.3	1.9	-5.1	-1.0	0.1	-2.4	4.1
Waist circumference	1.5	5.6	19.3	-0.1	-4.4	1.1	-2.9	-1.8	0.8	-0.9	3.4
Standing height	1.5	14.7	26.0	-2.7	3.2	-3.9	-3.8	4.6	-5.1	-4.3	-1.8
Osteoporosis (self-reported)	1.5	1.9	4.0	-1.6	0.4	-1.3	-0.6	2.0	-1.6	-1.3	-1.5
Tinnitus: Yes, now most or all of the time	1.5	1.8	3.6	1.1	-0.0	1.4	0.2	-1.9	1.3	1.6	1.7
Pain experienced in last month	1.5	2.6	5.4	-0.8	0.5	-1.5	-2.1	2.3	-1.9	-1.9	-0.8
Alzheimer’s Disease (in mother)	1.4	1.7	4.7	2.2	0.4	0.4	-1.7	-0.4	-0.5	-1.3	1.8
LDL Cholesterol	1.4	2.3	5.8	-0.4	2.3	-1.5	-1.0	0.9	-1.5	-2.4	-0.8
Ever used hormone-replacement therapy (HRT)	1.4	1.7	3.7	0.8	1.9	-0.3	1.9	0.3	1.9	1.4	-0.3
Systolic blood pressure, automated reading	1.4	4.2	10.9	1.2	-3.3	2.0	-0.9	-3.0	0.9	0.1	2.4
Fed-up feelings	1.4	2.5	5.5	1.0	-2.3	2.4	0.0	-1.6	1.6	1.5	1.1
Had other major operations	1.4	1.8	8.0	-2.8	1.7	-0.3	0.7	1.4	0.3	0.1	-0.8
Hayfever/allergic rhinitis (self-reported)	1.4	1.8	5.1	-2.3	1.2	-2.2	-0.5	1.0	-1.1	-0.7	-0.5
Hip circumference	1.4	5.9	16.8	0.5	-4.1	1.1	-3.9	-0.7	0.2	-1.9	3.1
Time employed in main current job	1.4	1.6	5.2	-0.8	0.0	0.2	-2.3	-0.3	-0.9	-2.3	0.9
Arm predicted mass (right)	1.4	7.0	22.9	0.6	-3.1	1.9	-4.8	-0.9	-0.1	-2.2	3.7
Illnesses of siblings: Diabetes	1.4	1.7	2.9	1.3	-0.6	1.0	0.6	-1.7	1.7	1.4	1.6
Fasting Glucose	1.3	1.6	5.7	1.8	-2.4	-0.4	-1.6	-0.2	0.6	-0.7	0.6
Had menopause	1.3	1.6	2.5	-1.3	1.5	-1.4	1.2	1.5	-0.7	0.1	-1.6
Lung cancer (father)	1.3	1.5	3.4	1.7	-1.8	1.3	0.1	-1.3	0.2	0.5	1.4
Glaucoma (self-reported)	1.3	1.5	7.0	-0.1	-0.5	-0.1	1.4	-1.3	0.8	2.6	-0.1
Medication: Amlodipine	1.3	1.8	3.8	0.9	-0.8	1.5	1.5	-1.4	1.9	1.3	1.0
Arm fat-free mass (right)	1.3	6.9	20.5	0.6	-2.9	2.0	-4.5	-1.3	0.2	-2.0	4.0
Leg fat-free mass (right)	1.3	6.9	23.8	0.3	-2.8	1.9	-4.9	-0.5	-0.0	-2.2	3.8
Leg predicted mass (right)	1.3	6.7	23.5	0.2	-2.8	1.8	-4.8	-0.5	-0.1	-2.2	3.7
Alcohol drinker status: Never	1.3	1.6	3.8	0.4	-1.8	1.5	-1.2	-1.0	0.3	-0.9	2.0
Basal metabolic rate	1.3	7.4	24.2	0.6	-3.1	1.8	-4.9	-0.9	-0.0	-2.3	3.9
Arm predicted mass (left)	1.3	6.5	18.5	0.8	-3.0	2.0	-4.3	-1.3	0.4	-1.7	3.9
Prostate Cancer	1.2	1.6	4.3	-0.0	-0.1	1.1	2.0	0.1	1.2	2.1	-1.4
HDL Cholesterol	1.2	2.0	7.6	0.4	1.3	0.4	2.8	0.2	0.5	1.9	-1.5
Current tobacco smoking	1.2	2.0	8.2	1.5	-2.9	-0.6	-1.7	-0.2	-0.9	-1.2	0.2
Impedance of leg (left)	1.2	5.9	13.1	-0.9	2.7	-3.4	2.8	1.8	-1.8	0.8	-3.6
Alcohol usually taken with meals	1.2	2.0	5.8	0.8	2.4	-0.8	1.8	1.1	1.0	1.1	-1.4
Illnesses of mother	1.2	1.5	3.5	-0.5	0.6	-1.9	-0.0	1.5	-1.8	-0.5	-1.6
Mouth/teeth dental problems: Loose teeth	1.2	1.4	3.5	1.9	0.1	0.6	1.6	-0.9	1.1	1.4	-0.7
Medication: Allopurinol	1.2	1.6	5.1	0.3	-2.0	2.3	-0.3	-1.1	1.0	0.5	0.9
Heart disease (mother)	1.2	1.5	3.1	-0.1	-0.9	1.3	1.2	-1.5	1.8	1.2	1.0
Whole body fat-free mass	1.2	6.8	24.8	0.3	-2.5	1.7	-5.0	-0.5	-0.4	-2.5	3.7
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.2	3.4	-1.9	1.3	-0.4	0.4	1.7	-0.4	-0.0	-1.2
Arm fat-free mass (left)	1.2	6.2	16.4	0.6	-3.0	2.2	-4.0	-1.3	0.4	-1.5	3.8
Bipolar Disorder or Schizophrenia	1.1	2.7	8.7	0.8	-0.6	0.6	2.4	-1.3	2.1	3.0	-0.3
Height	1.1	22.1	43.0	-2.9	2.7	-4.8	-5.0	5.8	-6.6	-5.5	-2.3
Chronotype (morning person)	1.1	2.6	5.2	-0.4	-1.1	2.2	1.1	-1.7	1.8	2.3	1.5
Medication: Levothyroxine sodium	1.1	1.8	7.1	-2.7	-0.5	-1.1	-1.6	1.5	-0.8	-0.7	0.3
Hearing difficulty/problems with background noise	1.1	1.7	3.3	0.5	1.4	-1.6	-0.2	1.8	-1.5	-0.9	-1.6
Headache pain in last month	1.1	2.0	4.4	-0.6	-0.4	1.8	2.1	-0.8	1.8	1.9	-0.2
Migraine (self-reported)	1.1	1.4	4.9	-0.2	0.6	1.0	2.2	-0.3	1.0	1.8	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.2	3.1	-1.8	0.4	-1.1	-0.8	1.6	-0.5	-0.4	-1.4
Whole body water mass	1.1	6.3	23.4	0.3	-2.4	1.6	-4.8	-0.4	-0.4	-2.5	3.5
Eye problems/disorders: Glaucoma	1.1	1.3	4.6	0.5	-1.5	0.5	0.7	-1.2	1.1	2.1	0.7
Medication: Bendroflumethiazide	1.1	1.7	4.9	0.4	-0.7	1.1	0.1	-2.2	1.3	0.1	2.2
Fractured/broken bones in last 5 years	1.1	1.4	4.4	0.0	-1.2	1.1	0.6	-1.1	1.6	2.1	0.4
Diastolic blood pressure, automated reading	1.1	3.5	12.9	0.6	-3.6	1.9	-2.2	-1.4	-0.1	-1.3	1.6
Heart disease (siblings)	1.1	1.3	3.6	1.4	-0.8	0.9	0.1	-1.4	1.3	0.0	1.9
Smoking Status	1.0	2.4	6.4	1.3	-1.5	-1.0	-2.5	-0.9	-0.8	-2.2	1.4
Lung FVC	1.0	5.3	10.4	0.4	0.0	3.0	3.2	-2.3	3.0	2.7	1.4
Severe depression (siblings)	1.0	1.2	2.9	-0.4	-0.4	1.1	0.9	-1.0	1.7	1.5	0.8
Father’s age at death	1.0	1.3	2.5	0.4	1.3	1.3	1.6	0.9	1.1	1.4	-0.7
Pulse rate	1.0	1.7	6.4	-0.7	0.4	-0.1	2.5	0.8	0.4	1.4	-1.9
Comparative body size at age 10	1.0	2.9	5.9	1.4	-1.8	2.1	-1.9	-1.8	0.1	-0.6	2.4
Number of children fathered	1.0	1.1	1.9	0.5	-0.1	1.4	0.2	-1.3	1.4	1.3	1.1
Emphysema/chronic bronchitis	1.0	1.1	2.7	1.6	0.9	0.9	0.8	-1.2	1.3	0.6	0.9
Financial situation satisfaction	1.0	1.2	3.8	-0.5	1.0	-0.6	1.9	0.4	-0.2	0.9	-1.8
Ever smoked	1.0	1.7	6.0	0.2	1.2	-2.5	-0.5	1.0	-1.0	-1.4	-1.4
Crohns Disease (2017)	0.9	1.9	7.0	1.0	2.7	-0.8	1.8	0.5	-0.1	0.5	-1.7
Blood Eosinophil Count	0.9	6.8	17.2	-0.3	-0.5	-2.0	-3.6	-2.5	-1.8	-3.2	4.2
Impedance of leg (right)	0.9	4.6	10.2	-0.4	2.4	-3.2	2.4	1.2	-1.7	0.3	-3.2
Maternal smoking around birth	0.9	1.2	3.0	1.7	-1.5	0.7	-0.3	-1.2	1.2	0.8	0.8
Supplements: Glucosamine	0.9	1.2	3.1	0.3	1.7	-0.6	1.8	0.9	0.9	1.0	-0.7
Trunk fat-free mass	0.9	5.2	21.1	-0.0	-1.7	1.3	-4.6	-0.1	-0.8	-2.6	3.0
Happiness	0.9	1.1	3.0	-0.4	1.2	-1.1	0.1	1.3	-1.7	-0.6	-1.1
Trunk predicted mass	0.9	5.2	21.0	0.1	-1.7	1.3	-4.6	-0.2	-0.7	-2.5	3.0
Birth weight of first child	0.9	1.7	3.3	-1.4	0.7	-1.3	-1.8	1.4	-1.2	-1.6	-0.6
Eye problems/disorders: None of the above	0.9	1.0	2.3	1.0	0.6	-0.1	-1.3	0.8	-1.5	-1.5	-0.3
Smoking status: Current	0.9	1.4	4.6	1.4	-2.1	-0.7	-1.4	0.1	-1.0	-1.2	-0.2
Commuting to job workplace: Cycle	0.9	1.0	1.9	-0.4	1.3	1.2	0.6	-0.8	1.1	1.4	1.0
Bipolar Disorder (2018)	0.8	1.2	4.3	-1.7	0.4	-0.3	0.9	0.1	2.1	1.3	0.2
Crohns Disease (2012)	0.8	1.2	3.8	1.1	1.2	0.1	1.9	-0.4	0.6	1.6	-0.3
Primary Biliary Cirrhosis	0.8	1.1	2.4	-0.7	0.7	0.4	0.3	1.2	-1.6	-1.5	-1.2
Ulcerative Colitis	0.8	1.2	3.0	0.9	1.3	-1.7	0.1	1.1	-0.6	-0.7	-1.3
Waist Hip Ratio (WHR)	0.8	3.7	12.9	-2.8	1.2	-3.6	0.5	0.9	-2.0	-0.3	-1.3
Ever had hysterectomy (womb removed)	0.8	0.9	1.8	0.0	0.6	-0.4	-1.3	1.3	-1.1	-1.3	0.1
Hayfever, allergic rhinitis or eczema	0.8	1.7	6.3	-1.7	2.5	-0.5	0.2	0.5	-1.5	-1.0	-0.6
Alcohol intake versus 10 years previously	0.8	1.3	4.2	1.9	-2.0	0.9	-0.9	-0.4	0.0	0.5	0.6
Depression (self-reported)	0.8	1.0	3.9	-0.9	-2.0	0.3	-1.1	-0.2	0.8	1.0	0.6
Chest pain or discomfort	0.8	1.2	3.2	1.3	-0.4	0.9	0.8	-1.8	1.0	0.4	1.3
Had major operations	0.8	0.9	2.6	0.9	-0.1	1.6	-0.1	-0.8	1.2	0.3	1.2
Breast cancer (self-reported)	0.8	1.0	2.9	1.7	0.0	-0.1	0.3	-1.2	0.9	0.7	1.4
Osteoarthritis (self-reported)	0.8	1.0	2.2	1.5	-1.0	1.3	0.5	0.0	1.4	0.5	0.8
Mother’s age at death	0.8	1.0	2.5	0.8	0.8	0.8	-0.1	-1.2	1.5	0.1	1.6
Average weekly beer plus cider intake	0.8	1.2	4.7	-2.2	-1.7	0.2	-0.5	-0.2	-1.3	0.1	-0.1
Unable to work because of sickness or disability	0.8	1.1	2.3	0.5	-1.0	1.4	0.6	-1.4	1.5	0.7	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	3.2	1.1	-0.9	0.3	0.8	0.8	0.9	1.8	-1.1
Pulse wave reflection index	0.7	0.9	2.8	-0.1	0.9	-1.7	0.3	1.1	-0.4	0.2	-1.4
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	2.7	-0.7	0.4	-1.6	0.5	1.1	-0.6	1.3	-1.5
Gout (self-reported)	0.7	1.0	2.7	1.3	-1.6	1.2	-0.9	-0.7	0.5	0.2	0.6
Overall health rating	0.7	1.5	7.5	0.0	-2.7	1.6	-0.7	-0.6	0.8	0.7	0.7
Illnesses of father: Heart disease	0.7	0.9	2.2	-0.2	0.9	0.3	1.4	1.0	1.5	1.1	-0.6
Ever had bowel cancer screening	0.7	0.9	2.6	-0.5	-1.1	1.6	0.5	-0.6	0.8	1.0	0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	3.6	-0.8	1.9	-1.3	-0.3	0.2	-0.5	-0.2	-0.3
Guilty feelings	0.7	1.1	4.2	0.4	0.5	0.7	1.3	-0.5	1.1	2.1	-0.3
Number of operations (self-reported)	0.7	1.1	4.7	-0.6	2.2	0.5	-0.1	1.6	0.6	-0.7	-0.1
Cholesterol lowering medication	0.7	1.0	2.0	0.8	-1.4	1.1	-1.1	0.8	-0.4	-1.1	0.8
Schizophrenia vs Biploar Disorder	0.6	0.8	1.6	1.0	-1.1	0.4	1.0	-0.6	-0.7	1.3	-0.7
Systolic Blood Pressure	0.6	2.8	8.0	1.1	-2.8	2.4	-0.1	-2.4	0.6	-0.2	1.4
Number of treatments/medications taken	0.6	1.0	3.1	0.1	-0.6	1.6	0.3	-0.6	1.8	0.4	1.2
Age when periods started (menarche)	0.6	1.5	5.7	-0.6	0.5	-0.2	-2.4	1.0	-0.9	-1.9	0.5
High blood pressure	0.6	1.6	4.9	1.0	-1.1	2.2	-0.2	-1.4	0.6	-0.6	1.8
High blood pressure (mother)	0.6	0.9	2.4	0.5	0.3	1.3	0.7	-1.0	1.5	0.4	1.1
Medication: Ramipril	0.6	0.8	1.9	0.1	-0.4	0.8	-1.4	1.0	-0.6	-1.4	0.7
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	1.9	1.4	-1.0	0.5	-0.4	-0.3	1.1	0.5	1.0
Medication: Cholesterol lowering	0.6	1.0	4.2	0.9	-0.6	2.1	0.5	-0.7	1.1	-0.3	0.6
Prospective memory result	0.6	0.7	2.6	0.6	-1.6	1.4	-0.2	0.1	0.7	0.5	0.3
Loud music exposure frequency	0.6	0.6	2.0	1.4	-0.1	0.2	0.4	-1.3	0.7	0.2	0.8
Medication: Blood pressure	0.6	1.1	3.2	0.7	-0.7	1.8	-0.0	-1.1	1.0	-0.5	1.5
Number of full sisters	0.6	0.7	2.7	-0.2	-0.7	1.6	0.2	0.4	0.8	1.1	0.6
Leg pain on walking	0.6	0.8	3.7	1.9	-0.8	0.4	0.3	-1.2	0.6	-0.1	0.4
Mood swings	0.6	1.0	2.8	1.1	-0.6	1.2	1.2	-0.3	0.7	1.7	-0.7
Back pain experienced in last month	0.6	0.9	1.9	1.4	1.2	0.4	-0.2	-1.0	0.7	0.0	1.4
Mineral and other dietary supplements	0.6	0.9	2.5	-1.6	-1.2	-0.8	-0.5	-0.2	-1.1	-0.5	-0.9
Commuting to job workplace: Public transport	0.6	0.7	2.2	-1.5	1.3	-1.0	0.1	0.1	-0.3	0.3	-0.4
Supplements: Fish oil (including cod liver oil)	0.6	0.8	3.9	0.3	2.0	0.3	1.0	0.5	0.7	0.6	-0.0
Medication: Lisinopril	0.6	0.8	2.7	0.2	-0.5	0.9	-0.9	-1.2	0.4	-0.5	1.6
Ever had prostate specific antigen (PSA) test	0.6	0.6	1.8	-0.4	0.2	0.7	1.2	0.2	0.7	1.3	-0.7
Supplements: Calcium	0.6	0.6	2.0	-0.6	-0.8	0.7	-0.8	1.4	-0.6	0.2	-0.5
Deep venous thrombosis (DVT) (self-reported)	0.6	0.7	2.4	1.6	-0.3	1.0	-0.2	-1.3	0.5	0.1	0.7
Alcohol drinker status: Previous	0.6	0.7	2.2	0.4	-0.8	0.2	-1.5	-0.2	-0.6	-1.2	1.0
Bipolar Disorder (2011)	0.5	0.5	1.7	0.8	0.6	0.0	1.1	-1.3	0.0	0.0	0.0
Lung FEV1/FVC ratio	0.5	2.8	9.0	0.5	-3.0	0.9	-2.1	-1.0	-0.2	-0.8	2.5
Average weekly spirits intake	0.5	0.6	2.0	1.0	-0.6	0.7	-1.1	-0.1	-0.0	-0.4	1.4
Sensitivity / hurt feelings	0.5	0.8	2.2	1.1	-0.5	1.1	0.6	-1.5	0.4	0.6	0.7
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	3.3	-1.8	-0.2	0.6	-0.6	0.5	-0.5	-0.8	-0.4
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.7	3.0	0.2	-1.5	1.7	-0.6	-0.4	-0.1	0.0	0.5
Heart attack	0.5	0.6	2.6	0.8	-0.7	1.6	0.0	-0.2	0.8	-0.2	0.5
Pain all over the body in last month	0.5	0.6	1.6	0.4	-1.3	1.0	-0.7	-0.5	0.1	0.1	1.1
Number of live births	0.5	0.7	1.9	-0.0	0.5	-1.4	1.0	1.0	-0.5	-0.1	-1.1
Mouth/teeth dental problems: Dentures	0.5	0.8	2.3	0.8	-0.5	0.3	0.4	-1.5	0.7	0.0	1.5
Exposure to tobacco smoke at home	0.5	0.5	1.1	-1.0	-1.0	0.1	0.9	0.2	0.5	1.0	-0.3
Peak expiratory flow (PEF)	0.5	1.1	4.5	1.3	-0.1	0.8	-1.0	-1.0	0.0	-0.3	2.1
Medication: Ventolin 100micrograms inhaler	0.5	0.7	2.5	-0.0	0.2	-1.0	0.4	1.2	-0.5	0.2	-1.6
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	1.8	0.4	-0.2	0.0	-1.1	-0.6	-0.1	-0.8	1.4
Medication: Omeprazole	0.5	0.6	2.6	-0.6	-0.1	-1.6	-0.2	0.4	-0.7	-0.7	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.5	1.2	0.5	0.6	1.2	-0.9	0.3	-0.0	-0.4
Pulse rate, automated reading	0.5	1.6	7.2	-0.5	-0.7	0.1	1.8	1.1	-0.1	0.6	-2.7
Family relationship satisfaction	0.5	0.6	1.1	0.9	1.1	-0.4	0.5	1.0	-0.0	0.9	-0.6
Hypertension (Self-reported)	0.5	1.3	4.0	0.9	-0.8	2.0	-0.0	-1.4	0.6	-0.5	1.7
Smoking status: Previous	0.5	0.8	2.5	-0.3	1.2	-1.6	-0.9	0.3	-0.4	-1.1	-0.1
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.1	-1.5	0.1	-1.0	0.8	0.1	-0.1	0.5	-0.7
Medication for cholesterol	0.5	0.8	2.6	-0.1	0.1	-1.6	-0.9	0.5	-1.3	-0.5	-0.8
Number of self-reported non-cancer illnesses	0.5	0.8	2.0	-0.9	-0.4	1.4	0.4	-0.4	1.4	0.2	1.2
Wears glasses or contact lenses	0.5	0.6	1.9	-0.4	-1.4	-0.9	0.1	0.5	0.5	0.8	-0.7
High cholesterol (Self-reported)	0.5	0.9	2.9	0.7	0.4	0.5	-0.8	1.5	-0.7	-1.7	0.3
Myopia	0.5	0.7	2.0	0.4	-1.3	0.5	0.6	0.8	-0.4	0.4	-1.4
Alzheimer’s Disease (including proxy)	0.4	0.6	3.4	1.8	0.9	0.6	-0.0	-0.2	0.2	0.2	0.4
Respiratory disease	0.4	0.9	3.8	-1.3	1.9	0.2	-0.1	0.5	0.2	-1.1	-0.2
Angina	0.4	0.5	1.2	-0.4	-0.9	1.1	0.5	-0.5	0.7	0.6	0.2
Taking other prescription medications	0.4	0.6	2.1	-0.0	-1.4	0.3	0.5	0.2	1.4	0.7	-0.1
Multivitamins +/- minerals	0.4	0.5	2.1	-0.5	0.6	-0.3	0.1	1.5	0.6	0.2	-0.7
Medication: Atenolol	0.4	0.5	2.1	-0.4	-0.2	1.4	1.0	-0.4	0.5	0.4	0.1
Sitting height	0.4	2.7	6.7	-0.1	1.9	-0.3	-2.1	1.1	-2.6	-2.3	0.6
Past tobacco smoking	0.4	0.8	3.0	-0.4	-1.1	1.7	0.6	-0.3	0.4	1.1	0.5
Hair/balding pattern: Pattern 2	0.4	0.5	2.0	0.9	1.4	0.1	0.5	-0.8	0.3	0.3	0.3
Ever unenthusiastic/disinterested for a whole week	0.4	0.4	1.5	-0.2	-1.2	-0.2	-0.7	1.0	-0.5	-0.2	-0.5
Worrier / anxious feelings	0.4	0.8	2.6	-0.3	-1.6	1.5	-0.5	-0.6	0.6	0.6	0.6
Asthma	0.4	0.8	2.7	-0.4	0.3	0.0	-1.6	0.7	-0.3	-1.6	0.1
Chronic bronchitis/emphysema (mother)	0.4	0.4	1.4	-0.6	-1.2	0.3	-0.7	-0.7	0.6	-0.0	0.5
Neck or shoulder pain in last month	0.4	0.6	2.2	-0.3	-0.2	0.3	1.5	-1.3	0.7	0.3	0.3
Angina (self-reported)	0.4	0.5	1.5	-0.3	-1.1	1.2	0.5	-0.4	0.5	0.6	0.1
Supplements: Vitamin C	0.4	0.4	1.5	1.2	0.3	-0.2	0.2	-0.6	0.0	-0.2	1.2
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	1.6	-1.2	0.7	-0.6	-1.2	0.9	-1.3	-0.8	-0.2
Qualifications: nursing, teaching	0.4	0.6	1.7	-0.3	0.3	-0.8	-0.6	1.1	-0.9	-1.3	-0.5
Commuting to job workplace: Walk	0.4	0.4	1.1	1.1	0.3	-0.5	-0.8	0.8	0.4	-0.3	0.7
Eye problems/disorders: Cataract	0.4	0.4	1.2	-0.7	-0.2	-0.5	-0.4	0.6	-0.9	-1.1	-0.3
Medication: Atorvastatin	0.4	0.5	1.7	0.1	0.5	-0.5	0.9	1.3	-0.3	0.2	-1.0
Age started oral contraceptive pill	0.4	0.4	1.3	-0.3	-0.4	-1.0	-1.2	0.6	-0.3	-0.7	0.1
Heart attack/myocardial infarction (self-reported)	0.4	0.5	2.2	0.4	-0.9	1.5	0.1	0.0	0.7	-0.2	0.3
Lupus	0.3	0.4	1.1	-0.6	-0.6	0.8	-0.2	-0.4	-0.6	-1.0	0.7
Neuroticism (2016)	0.3	0.4	1.4	-0.7	0.1	-1.2	0.1	0.7	-0.0	0.5	-0.5
Heel T-Score	0.3	2.3	10.1	1.3	1.1	0.5	0.8	-3.2	0.5	-0.4	2.0
Allergy or Eczema	0.3	0.9	3.0	-1.6	1.7	0.3	0.6	0.1	-0.9	-0.6	-0.5
Cardiovascular Disease	0.3	1.1	2.5	0.8	-0.7	1.6	0.2	-1.1	0.3	-1.2	1.5
Tanning	0.3	3.5	7.9	-0.6	1.4	0.7	2.6	-1.9	2.5	2.8	0.8
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.1	-0.7	-0.3	0.0	-0.4	0.8	-1.0	-0.4	-1.0
Diabetes (father)	0.3	0.4	1.0	-0.1	-0.8	-0.1	-0.1	1.0	-0.4	-0.4	-1.0
Diabetes (mother)	0.3	0.4	1.4	-0.5	-0.5	0.6	0.4	-0.5	0.7	1.2	-0.3
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	1.1	-1.0	1.0	0.1	0.0	-0.5	-0.0	-0.7	0.1
Medication: Lansoprazole	0.3	0.3	1.1	-0.9	0.1	0.6	0.6	-1.0	0.3	0.3	0.1
Hair/balding pattern: Pattern 4	0.3	0.7	2.3	0.2	-1.4	-0.3	-1.5	0.5	-0.1	-0.7	0.3
Birth weight	0.3	0.5	2.5	-0.1	0.1	0.2	1.0	0.1	0.5	1.6	-0.8
Number of full brothers	0.3	0.4	1.7	-0.2	0.2	-0.1	1.3	-0.3	1.0	0.5	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.5	-1.2	-0.3	0.1	0.4	0.3	0.2	0.9	-0.7
Shortness of breath walking on level ground	0.3	0.4	1.0	-0.4	0.6	0.3	1.0	-0.9	0.5	0.6	0.3
Average weekly red wine intake	0.3	0.5	1.1	0.8	1.0	-0.4	-0.3	0.4	-0.7	-1.0	0.2
Loneliness, isolation	0.3	0.4	2.2	0.7	-0.4	0.2	0.4	-0.5	0.5	1.5	-0.1
Illnesses of father: None of the above (group 1)	0.3	0.4	1.3	-0.1	0.5	-0.9	-0.1	0.2	-1.1	-0.5	-0.7
Irritability	0.3	0.5	2.5	0.0	-1.6	-0.4	-0.6	-0.4	0.1	0.8	0.4
Vascular/heart problems diagnosed by doctor	0.3	0.9	3.0	-0.3	1.0	-1.7	0.7	0.6	-0.1	1.1	-1.2
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	1.9	-0.3	-0.4	-1.4	-0.2	-0.1	-0.3	-0.6	-0.2
Basal cell carcinoma (self-reported)	0.3	0.3	0.9	-0.4	0.2	-0.6	0.4	1.0	0.7	0.6	-0.6
Depression (Nagel 2018)	0.2	0.3	1.1	-0.0	-0.4	1.1	-0.2	-0.8	0.4	0.2	0.3
Worry (Nagel 2018)	0.2	0.4	1.4	-0.9	0.5	-0.3	-0.0	1.0	0.0	0.2	-1.2
HbA1C	0.2	0.2	0.4	0.3	-0.6	0.1	-0.4	-0.4	0.6	-0.0	0.6
Rheumatoid Arthritis	0.2	0.2	0.5	0.0	-0.4	0.6	-0.4	-0.7	0.2	-0.5	0.7
Triglycerides	0.2	0.3	0.7	-0.2	-0.7	-0.3	-0.8	0.1	-0.6	-0.8	-0.1
Hearing difficulty/problems: Yes	0.2	0.3	0.9	0.2	-0.8	-0.6	-0.9	-0.4	0.0	-0.5	0.6
Vitamin and mineral supplements	0.2	0.3	1.0	-0.4	0.1	-0.4	-0.3	-0.7	-1.0	-0.4	-0.3
Supplements: Zinc	0.2	0.3	0.8	0.1	-0.2	0.4	0.5	0.6	0.6	0.9	0.3
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	0.4	-0.6	0.3	0.6	0.5	-0.5	0.4	0.6	0.6
Stomach or abdominal pain in last month	0.2	0.3	1.5	-0.7	-1.2	0.2	-0.3	0.1	0.3	-0.3	0.2
Allergy	0.2	0.5	3.2	0.2	-1.8	-0.2	-0.6	0.1	0.4	0.6	0.1
Neuroticism score	0.2	0.3	1.2	-0.3	-0.6	1.1	-0.5	-0.6	0.4	0.5	0.3
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	3.9	-0.6	-0.4	0.7	-0.6	-0.8	-0.1	0.2	2.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	2.8	-0.8	-0.3	0.5	0.1	-0.7	-0.0	0.8	1.7
Tense / ‘highly strung’	0.2	0.4	1.3	-1.1	0.1	0.7	-0.3	0.7	0.1	0.4	-0.5
Blood clot in the leg (DVT)	0.2	0.2	1.0	1.0	-0.0	0.4	-0.3	-0.7	0.1	-0.1	0.2
High blood pressure (siblings)	0.2	0.3	0.7	0.9	-0.7	0.6	0.0	0.1	0.9	-0.5	0.2
Forced vital capacity (FVC), Best measure	0.2	0.8	3.4	-1.8	1.2	-0.7	0.5	0.2	-0.6	0.2	0.5
Health satisfaction	0.2	0.3	1.2	-0.0	1.1	-0.2	0.9	0.1	-0.5	-0.1	-0.3
Commuting to job workplace: Car/motor vehicle	0.2	0.3	0.9	0.1	-0.3	0.8	0.6	-0.9	-0.2	-0.2	0.0
Knee pain experienced in last month	0.2	0.3	0.7	-0.6	-0.7	0.6	-0.0	-0.8	0.4	-0.1	0.4
Asthma (self-reported)	0.2	0.4	1.1	-0.5	0.3	0.2	-1.1	0.6	0.0	-1.1	0.0
Miserableness	0.2	0.4	1.0	0.1	0.9	-0.6	1.0	-0.1	-0.0	0.3	-1.0
Medication: Blood pressure	0.2	0.5	2.0	0.3	-0.9	1.4	0.1	-0.2	0.5	0.2	0.6
Illnesses of father: High blood pressure	0.2	0.2	0.6	0.1	0.1	0.3	-0.8	0.5	0.1	-0.8	0.3
Ever depressed for a whole week	0.2	0.2	0.7	-0.0	0.2	0.7	0.1	0.9	0.2	0.6	-0.5
Depressed Affect (Nagel 2018)	0.1	0.2	0.6	0.7	0.1	-0.3	0.5	-0.4	0.3	0.7	-0.5
Neuroticism (Nagel 2018)	0.1	0.2	0.6	0.5	0.1	-0.1	0.2	-0.2	0.3	0.8	-0.5
Mean Putamen Volume	0.1	0.1	0.4	0.2	0.1	-0.3	-0.2	0.4	-0.1	0.6	-0.6
Neuroticism	0.1	0.3	0.9	0.1	0.3	0.3	0.3	-1.0	0.5	0.9	0.2
Hair Pigment	0.1	2.5	7.8	0.5	-0.5	-0.8	-2.8	-0.5	-1.8	-2.8	0.5
Hand grip strength (left)	0.1	0.4	1.3	0.6	1.1	-0.2	0.0	-0.0	-1.0	-0.3	-0.2
Hand grip strength (right)	0.1	0.3	0.7	0.3	0.7	0.2	-0.5	-0.6	-0.7	-0.2	0.8
Forced vital capacity (FVC)	0.1	0.3	1.7	-0.8	0.2	0.2	-0.2	-0.4	-0.0	0.3	1.3
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.8	0.3	-0.9	0.4	0.4	0.1	0.3	0.1	-0.3
Hair/balding pattern: Pattern 3	0.1	0.2	0.8	0.6	0.6	-0.9	-0.0	0.2	-0.2	-0.1	0.1
Breastfed as a baby	0.1	0.2	0.6	-0.8	0.3	0.3	0.5	-0.0	0.4	0.5	-0.0
Medication: Seretide 50 evohaler	0.1	0.1	0.2	0.2	0.4	0.3	-0.0	0.2	0.4	-0.1	-0.3

Hub : Genes

ZMIZ2

Models

Trait associations