Best TWAS P=6.35e-19 · Best GWAS P=7.73e-31 conditioned to 3.56e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Female) | CERS5 | 0.09 | 0.03 | lasso | 3 | 0.05 | 0.01750 | -1.49 | -5.4 | 5.7e-08 | -0.53 | 0.05 | 0.23 | FALSE |
| 2 | GTEx | Testis | FAIM2 | 0.27 | 0.09 | lasso | 5 | 0.06 | 0.00093 | 9.67 | -8.9 | 6.3e-19 | -0.77 | 0.04 | 0.85 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | FAIM2 | 0.02 | 0.00 | blup | 71 | 0.01 | 0.00853 | -0.42 | -5.6 | 1.9e-08 | -0.36 | 0.16 | 0.13 | TRUE |