Best TWAS P=5.63e-09 · Best GWAS P=1.93e-10 conditioned to 1.05e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Frontal Cortex BA9 | TEX29 | 0.45 | 0.10 | lasso | 8 | 0.24 | 4.2e-07 | -4.0 | -5.8 | 5.6e-09 | -0.40 | 0.05 | 0.56 | TRUE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ARHGEF7 | 0.09 | 0.07 | blup | 142 | 0.08 | 3.1e-09 | -4.4 | 5.4 | 6.0e-08 | 0.39 | 0.96 | 0.04 | FALSE |