[Hub]/) : Traits : Arm fat mass (right) :

chr16:2,868,641-5,706,977

Best TWAS P=8.95e-20 · Best GWAS P=3.52e-27 conditioned to 1.8e-09

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta UBN1 0.18 0.15 lasso 4 0.14 6.8e-08 5.9 -5.3 1.0e-07 -0.04 0.11 0.88 FALSE
2 GTEx Brain Cerebellum SLX4 0.33 0.14 lasso 3 0.10 6.8e-04 4.9 -5.2 1.9e-07 -0.01 0.16 0.05 FALSE
3 GTEx Brain Frontal Cortex BA9 NLRC3 0.50 0.18 enet 30 0.33 1.6e-09 3.0 -5.9 4.0e-09 0.03 0.44 0.06 TRUE
4 GTEx Brain Hippocampus CLUAP1 0.37 0.10 lasso 5 0.09 4.9e-03 4.5 5.4 6.8e-08 0.02 0.17 0.06 FALSE
5 GTEx Esophagus Mucosa UBN1 0.12 0.06 lasso 3 0.08 5.1e-06 5.4 -5.7 1.0e-08 -0.05 0.11 0.88 FALSE
6 GTEx Esophagus Muscularis UBN1 0.18 0.19 lasso 4 0.19 9.1e-12 5.9 -5.8 9.0e-09 -0.04 0.20 0.80 FALSE
7 GTEx Nerve Tibial UBN1 0.14 0.12 lasso 4 0.11 5.6e-08 5.9 -5.9 3.8e-09 -0.04 0.20 0.79 TRUE
8 GTEx Skin Sun Exposed Lower leg CLUAP1 0.34 0.25 lasso 6 0.27 1.1e-22 4.9 5.2 1.8e-07 0.04 1.00 0.00 FALSE
9 GTEx Skin Sun Exposed Lower leg PPL 0.10 0.04 lasso 6 0.02 5.7e-03 5.4 5.3 1.2e-07 0.05 0.08 0.71 FALSE
10 GTEx Skin Sun Exposed Lower leg UBN1 0.16 0.15 lasso 5 0.17 9.5e-14 5.9 -5.5 4.5e-08 -0.05 0.22 0.78 FALSE
11 ROSMAP Brain Pre-frontal Cortex RP11-462G12.1 0.11 0.07 enet 18 0.06 1.1e-08 -10.5 -9.1 8.9e-20 0.86 0.00 1.00 TRUE
12 The Cancer Genome Atlas Bladder Urothelial Carcinoma NLRC3 0.05 0.01 blup 39 0.02 9.8e-03 5.1 -5.2 2.2e-07 -0.09 0.00 0.84 FALSE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ROGDI 0.03 0.04 lasso 3 0.03 1.6e-04 5.4 -5.3 1.3e-07 0.01 0.01 0.96 FALSE