Best TWAS P=1.13e-07 · Best GWAS P=2.15e-07 conditioned to 0.551
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Lung | RP11-552F3.10 | 0.12 | 0.02 | lasso | 2 | 0.03 | 4.4e-03 | 5.1 | -5.3 | 1.1e-07 | -0.94 | 0.02 | 0.48 | TRUE |
2 | The Cancer Genome Atlas | Lung Adenocarcinoma | TRIM47 | 0.04 | 0.01 | blup | 30 | 0.03 | 2.7e-04 | 5.1 | -5.3 | 1.2e-07 | -0.86 | 0.01 | 0.71 | FALSE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | TRIM47 | 0.06 | 0.06 | blup | 30 | 0.06 | 1.6e-06 | 5.1 | -5.1 | 2.9e-07 | -0.66 | 0.01 | 0.99 | FALSE |