Best TWAS P=5.28e-13 · Best GWAS P=1.02e-12 conditioned to 0.877
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Cerebellar Hemisphere | BAIAP2 | 0.36 | 0.01 | enet | 22 | 0.02 | 8.5e-02 | 3.7 | -6.4 | 1.4e-10 | 0.43 | 0.04 | 0.14 | TRUE |
2 | GTEx | Muscle Skeletal | RPTOR | 0.14 | 0.05 | enet | 27 | 0.09 | 8.4e-09 | -6.1 | -7.2 | 5.3e-13 | 0.62 | 0.50 | 0.49 | TRUE |
3 | GTEx | Muscle Skeletal | CTD-2561B21.4 | 0.06 | 0.04 | lasso | 7 | 0.03 | 2.3e-04 | -5.9 | -6.6 | 4.4e-11 | 0.64 | 0.14 | 0.78 | FALSE |