Best TWAS P=8.64e-09 · Best GWAS P=5.06e-12 conditioned to 0.000118
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | PKHD1 | 0.04 | 0.05 | lasso | 3 | 0.05 | 1.7e-06 | 5.5 | -5.8 | 8.6e-09 | -0.78 | 0.38 | 0.61 | TRUE |