[Hub]/) : Traits : Arm fat mass (right) : ← →

chr6:41,042,590-42,907,327

Best TWAS P=9.95e-11 · Best GWAS P=4.87e-11 conditioned to 0.00337

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts MED20 0.11 0.05 lasso 4 0.08 9.4e-07 -5.4 5.8 6.1e-09 0.46 0.76 0.20 FALSE
2 GTEx Colon Transverse MED20 0.17 0.01 enet 10 0.06 6.0e-04 5.0 5.7 1.4e-08 0.69 0.17 0.62 FALSE
3 GTEx Lung BYSL 0.08 0.03 lasso 4 0.02 4.9e-03 5.8 -5.5 4.1e-08 -0.80 0.16 0.74 FALSE
4 GTEx Thyroid FRS3 0.20 0.16 lasso 4 0.16 5.2e-12 5.8 5.5 3.8e-08 0.67 0.11 0.89 FALSE
5 The Cancer Genome Atlas Colon Adenocarcinoma MED20 0.05 0.00 blup 50 0.04 2.8e-03 4.8 6.5 1.0e-10 0.70 0.06 0.30 TRUE
6 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma MED20 0.04 0.03 lasso 3 0.04 7.3e-05 -5.4 5.4 6.3e-08 0.45 0.48 0.17 FALSE
7 The Cancer Genome Atlas Brain Lower Grade Glioma MED20 0.09 0.08 enet 12 0.09 5.5e-10 5.1 5.5 5.1e-08 0.62 0.94 0.06 FALSE
8 The Cancer Genome Atlas Liver Hepatocellular Carcinoma MED20 0.09 0.07 lasso 5 0.07 3.4e-04 -4.8 5.5 2.8e-08 0.51 0.17 0.56 FALSE
9 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma UBR2 0.10 0.01 blup 77 0.04 9.1e-03 4.5 -5.6 2.4e-08 0.01 0.01 0.58 TRUE
10 The Cancer Genome Atlas Prostate Adenocarcinoma MED20 0.04 0.06 enet 6 0.05 2.6e-06 4.8 5.4 5.5e-08 0.58 0.86 0.07 FALSE
11 The Cancer Genome Atlas Stomach Adenocarcinoma MED20 0.03 0.05 lasso 2 0.04 1.2e-03 -5.4 5.5 4.6e-08 0.44 0.11 0.10 FALSE